유사성과 인접성을 이용한 연결주의적 의미망에서의 설명 메카니즘

민창우,김명원,김영분 崇實大學校 生産技術硏究所 1996 論文集 Vol.26 No.1

기존의 기호주의적 인공지능 시스템이 추론을 하는데 있어서 유연성이 부족하다는 것은 잘 알려진 사실이다. 이러한 문제점을 해결하기 위해 신경망을 이용한 추론시스템들이 제안되었다. 그러나 이러한 시스템들은 추론한 결과를 설명하는 기능이 없다는 단점을 가지고 있다. 본 논문에서는 유연한 지식 표현과 추론을 위한 연결주의적 모텔로 이미 제안된 연결주의적 의미망 즉, CSN(Connectionist Semantic Network)을 기반으로 하여 추론결과를 설명할 수 있는 설명 알고리즘(justification algorithm)을 제안한다. 이 설명 알고리즘은 추론에 중요하게 영향을 미친 개념들을 설명하고, 개념들 사이의 유사도와 인접도를 계산함으로써 유사성과 인접성에 의한 추론을 설명할 수 있다. 본 논문에서는 실험을 통하여 제안된 설명 알고리즘의 수행과정을 보이고 타당성을 검토한다. We have recently proposed the Connectionist Semantic Network(CSN) as a model for flexible knowledge representation and inference based on neural networks. However, it is the case that netural networks lack transparency in knowledge representation adn reasoning, which causes difficulties in understanding and explaining reasoning process. In this paper, we preopose a justification algorithm for CSN using conceptual similarity adn contiguity. Our method, first, extracts important concepts relevant to the inference results and then computes similarity and contiguity among those concepts, from which a justificatio can be constructed. Simulation results show that our method is sufficiently powerful and flexible in justifying connectionist inference.

홍도항의 방파제 배치에 따른 정온도에 관한 실험적 연구

민일규,박한기,민병형,이명우 東亞大學校 海洋資源硏究所 1998 硏究論文集 Vol.11 No.1

Through a study as hydraulic model test that applied a calmness test to the coast of Hongdo harbor as an optimal surface arrangement we could reach the following conclusion 1. In case of proposal 1, if an invaded wave is H₁/₃=8.46m, T₁/₃=13.0sec of an each wave direction the harbor calmness is as follows. The wave height ratio is about 0.6 at the entrance of a harbor 0.2∼0.3 anchor area in general and the value under 0.1 when the wave(H₁/₃=2.0m) is invaded as usual. 2. The calmness effect is more favorable by breakwater extension as proposal 2 & 3, but if the high wave is assaulted the wave height ratio of anchor area is 0.1∼0.2 owing to the diffraction wave at a SSE, SE direction. 3. In case of proposal 4 the harbor calmness is considerable satisfactory at ail direction and the wave height ratio of harbor under 0.1 when the high wave is invaded. Thereafter, a study that analyze and compare with the hydraulic model test by numerical analysis about the problem of harbor calmness that a short period wave has superiority will be continued

구개 접근법에 의한 협골 축소 성형술

우순섭,민병일,김명진 大韓顎顔面成形再建外科學會 1993 Maxillofacial Plastic Reconstructive Surgery Vol.15 No.3

The prominent malar region has been recognized a sign of youth and beauty in caucasian who generally have a dolichocephalic and long face. But in the orients, especially Koreans who generally have a mesocephalic or brachycephalic face, it is considered an agressive, unesthetic facial appearance. So many patients require the shaving of prominent malar eminence and arch, and many methods of its reduction have been devised. For the exposure of malar complex, infraorbital skin incision, intraoral approach, preauricular approach, supraauricular scalp incision, and coronal approach have been used. And for the reduction of bony structure, direct shaving, contouring and repositioning of the malar complex after extirpation, and medially fracture of zygomatic arch have been used with its own merits. We performed the reduction malarplasty through intraoral approach. After two parallel oeteotomy at medial part of the zygomatic bone, the midsegment is removed. The posterior arch of zygoma was bended or green stick fractured. When more correction was required, the posterior arch was fractured medially through the step incision at skin. This method has a some advantages. Compared with the method for extirpation of malar complex, the infection rate is diminished, the resorption is small because of no free bone graft. And cheek drooping is prevented. Compared with the method of coronal approach, the surgical trauma is minimal. Now we report some cases of reduction malarplasty performed through intraoral approach and disscus the surgical technique and results.

응고제가 우유두부의 물성 및 관능적 특성에 미치는 영향

우나리야,이민선,박수진,강명화 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.5

Different types of coagulant and characteristics of its concentration added in the process of making milk curd were compared in this study. The pH of whey decreased when the amount of coagulant increased. The turbidity of whey was decreased when 5% of acetic acid and lemon juice were put into as coagulants. The texture of milk curd made with cow's milk and skim milk was measured the highest when acetic acid and lemon juice were added at 3, 5% of their concentration. The fracturability of milk curd made only with cow's milk decreased as the concentration of each coagulant increased. The cohesiveness was decreased as concentration of coagulant increased. The springiness was slightly changed depending on its coagulant but didn't show much of difference. The gummminess of milk curd made with cow's milk was increased when 3, 5% of coagulant was added. The result of sensory evaluation of milk curd showed that preference of milk curd wasn't depending on types of milk nor its coagulant. Also, flavor preference showed better when lemon juice was added. Preference in texture of milk curd was the highest made with cow's milk and skim milk. Preference in taste was high when 10% of lemon juice was added to skim milk and preference in its appearance showed higher when the alum was added as a coagulant to both cow's milk and skim milk than other coagulants.

운동분류에 따른 체구성 성분 및 BMI의 비교

최명화,권영우,김진해,민경선,민진아 한국스포츠리서치 2001 한국 스포츠 리서치 Vol.12 No.4

The purpose of the present was to investigate the body composition and BMI in different sports groups with classification of sports. 121 male collegiate athletes were recruited from varsity team of golf(n=10), field hokey(n=18), tennis(n=8), judo(n=17), weight lifting(n=27), boxing(n=19) and bicycle(n=22). Sports event can be classified as low static/low dynamic such as golf(LSLD), low static/high dynamic such as hokey and tennis(LSHD), high static/low dynamic such as judo and weight lifting(HSLD), high static/high dynamic(HSHD) such as boxing and bicycle. With classification of sports events, percentage of body fat was significantly higher with HSLD group compared to HSHD group, but no measurable difference was LSLD and LSHD groups. LBM was significantly greater with HSLD group compared to LSHD and HSHD groups. Furthermore BMI of the HSLD group was higher than the other groups(p<.05). In conclusion, high static/low dynamic group were greater in %fat, LBM, BMI than other groups. The differences observed between different sports groups and classification of sports are related to metabolic and dynamic properties in different sports events.

구강외과 수술용 스텐트 기반 영상유도 수술 시스템의 개발

이우진,김대승,이원진,이삼선,최순철,허민석,허경회,김명진,이지호 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.3

Purpose : The purpose of this study was to develop a stent-based image guided surgery system and to apply it to oral and maxillofacial surgeries for anatomically complex sites. Materials and Methods : We devised a patient-specific stent for patient-to-image registration and navigation. Threedimensional positions of the reference probe and the tool probe were tracked by an optical camera system and the relative position of the handpiece drill tip to the reference probe was monitored continuously on the monitor of a PC. Using 8 landmarks for measuring accuracy, the spatial discrepancy between CT image coordinate and physical coordinate was calculated for testing the normality. Results : The accuracy over 8 anatomical landmarks showed an overall mean of 0.56±0.16 mm. The developed system was applied to a surgery for a vertical alveolar bone augmentation in right mandibular posterior area and possible interior alveolar nerve injury case of an impacted third molar. The developed system provided continuous monitoring of invisible anatomical structures during operation and 3D information for operation sites. The clinical challenge showed sufficient accuracy and availability of anatomically complex operation sites. Conclusion : The developed system showed sufficient accuracy and availability in oral and maxillofacial surgeries for anatomically complex sites. (Korean J Oral Maxillofac Radiol 2009; 39 : 149-56)

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

알코올사용장애의 유형별 특징

임명호,백기청,이경규,홍성도,김현우,이민규 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.5

대체적으로 알코올성 장애는 이질적인 집단으로 이해되어지고 있으며, 이는 알코올성 장애의 예후와 치료가 유형에 따라 다르다고 보기 때문이다. 이러한 알코올성 장애는 음주 형태, 의존유형, 유전적 취약성(genetic vulnerability), 성격유형, 정신병리적 측면에 따라 여러 유형으로 나눌 수 있다. 본 논문은 Babor등(1992)이 분류한 A형, B형의 아형분류가 우리나라에서도 이용가능한 지를 알아보는 예비적 조사논문으로써 알코올리즘의 진단 및 이해를 기하고자 하였다. 만 18세 이상부터 만 65세 이하의 알코올중독 남자 환자 94명을 대상으로 15개의 변인에 따라 군집분석을 시행하였으며, A형과 B형의 두 아형군 및 정상대조군과의 인구학적 특성, 임상양태의 차이를 비교하였다. 결과는 다음과 같다. 1) A형, B형, 그리고 정상대조군간의 연령, 학력, 결혼상태, 종교 등의 인구학적 특성의 차이는 없었다. 2) B형은 음주시작연령, 과다한 음주를 시작한 연령, 문제를 일으킨 연령에서 A형에 비해 세 항목 모두에서 일찍 발현하는 것으로 나타났다. 또한 B형에서 A형보다 의존 정도가 더 심하며, 평균음주량 및 가장 많이 과음한 양에 있어서도 A형보다 많이 마시는 것으로 나타났다. 3) A형보다 B형에서 좀 더 1차가족 중에 알코올로 인한 문제가 있는 사람이 많이 있는 것으로 나타났다. 4) B형은 A형보다 소아청소년기에 있어서 좀 더 많은 행동문제가 있음을 나타냈다. 5) 내과적 합병증, 신체생리적 후유증 및 사회적 후유증 및 생활사 후유증 또한 B형에서 좀 더 심한 분포를 보이고 있었다. 6) 정신병리요소에서 B형은 우울, 불안, 적대감에 있어서 A형보다 모두 유의하게 심한 증상을 보였다. 7) A형, B형, 정상대조군의 세 군간에서 모두 유의한 차이를 보이는 신뢰성있는 척도는 음주일수, 의존정도척도, 생활사정도 척도, 내과적 합병증, 사회적 후유증등이었다. 8) 음주 사용척도는 두 아형군과 정상대조군을 구분하는데 매우 신뢰성이 있는 척도로 나타났다. 상기의 결과를 종합해보면, 알코올사용장애에 대하여 Babor등(1992)이 분류한 A형, B형의 아형분류는 우리나라에서도 비슷한 양상을 보였으며, 이의 적용은 향후 알코올사용장애의 진단 및 이해에 이용가능할 것으로 평가한다. Objective : Multiple typologies of alcoholics have been studied, such as Jellineck's disease concept classification, Cloninger's neurobiological learning model, Zucker's developmental model, DSM Ⅲ-R and DSM Ⅳ classification, and Babor's multidimensional typology. To study if Babor's typology modification could be used to classify Korean alcoholics, we grouped 95 male inpatient alcoholics into Babor's typology modification. Methods : This study employed cluster analysis of measures representing several dimensions : premorbid risk and vulnerability dependence severity and alcohol-related problems, chronicity and alcohol-related consequences, and comorbid psychopathology. We compared demographic and clinical characteristics among Babor's type A and type B alcoholics and normal control group. Results : Type B alcoholics showed more characteristic symptoms in family history, more childhood behavior problems, earlier onset, more drinking amount, and more dependence severity, more medical, social, physical problems, more life time severity, more depressive, anxiety, hostility, compared with type A alcoholics. The statistically significant variables differentiating three groups(type A, type B, normal control group) were drinking days, dependence severity, lifetime severity, medical, social consequence. Alcohol Use Inventory to Babor's typology of alcoholism was very useful scale differentiating three groups. Conclusion : Babor's typology of alcoholism was useful for classification of inpatient alcoholics of Korea. It can be helpful and applicable to clinical diagnosis and research in Korean alcoholic patients.

성인 지역사회 폐렴의 원인 미생물에 대한 전향적 다기관 연구 : Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

김민자,정희진,손장욱,심희선,박대원,박승철,우준희,강재명,김유겸,신완식,김양리,이환종,김지희 대한감염학회 2001 감염 Vol.33 No.1

Background : Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical as number of newer pathogens have been recognized in recent years. In the 3-year period prospective study we investigated adult patients with community-acquired pneumonia for Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi as potential etiologic agents. Methods : A prospective multicenter study was performed from May 1997 to April 2000. A total of 431 patients with community-acquired pneumonia under the inclusion criteria were examined for specific microbial diagnosis; sputum culture and PCR, and serologic teats including indirect immunofluorescence antibody (IFA) test for Legionella, and hemagglutination tests for Leptosoira, Hantaan virus and O. tsutsugamushi. Etiologic diagnosis was determined on the basis of the review of case record forms and specific laboratory diagnostic criteria. Results : During the study period a total of 385 sputum and 283 serum samples were examined. Legionella pneumonia was diagnosed in 2.3% (10/431) of the cases examined : 1.4% cases with PCR-positive (5/367) and 2.1% with positive IFA test (6/283). Leptospirosis and scrub typhus were diagnosed in 0.4% (1/252) and 2.0% (5/252), respectively. All 5 cases with scrub typhus occurred in late fall, and rash or eschar was not found. None of cases was Hantaan virus infection. Conclusion : The results suggest that Legionella, Leptospira, and O. tsutsugamushi should be considered in the etiologic diagnosis and empirical antibiotic therapy of community-acquired pneumonia. (Korean J Infect Dis 32:24∼31, 2001)

양수 다발성 수지 재접합수의 치험례 : 4 cases report

차진한,박명철,김우경,한근태,김수신,백세민 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.2

Since the first successful replantation operation, several reports have been recorded replantated finger survival with high success rates. But ten and nine digits amputations are not common. It is even more unusual to have all digits suitable for replantation. 4 cases are presented where replantation of ten and nine digits were done at the department of PRS. Guro Hospital, Korea University from March 1987 to Jun 1988. In these cases, the patients were young and healthy, all of ten and nine digits were sharply amputed near the proximal phalanx, so a replantation team of 8 surgeons in alternating fashion replanted all ten and nine digits over 30 hours and each patient received 28 pints of whole blood during the procedure. Under general anesthesia, replantatin of both started simultaneously. All digits survived completely except partial necosis of right little finger in case 1. The ischemic time of each digit ranged from 4 hours and 45 minutes to 31 hours as shown in table 5. The long ischemic time did not criticaly affected the survival of amputated digit. Follow-up was from 12 months to 20 months postoperatively. The functional evaluation revealed as follows: 1. The grasping power ranged 13 lb to 65 lb(average;39.7lb) 2. The pinching power with index finger ranged 5 lb to 15 lb(average:10.2 lb) 3. The palm to pulp distance ranged 0 cm to 6 cm.(average;2.2cm) 4. The two point discrimination ranged 2.5mm to 22mm.(average;7.8mm) 5. The shape of digits were acceptable aesthetically. 6. All 4 patients were able to use both hands well in all activities of daily living.