FCT 5 : Fractional laser-assisted topical imiquimod 5% cream treatment for recalcitrant common warts in children

( Hyun Chang Ko ),( Jeong Min Kim ),( Hyun Ho Cho1 ),( Won Jeong Kim ),( Je Ho Mun ),( Margaret Song ),( Hoon Soo Kim ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Conventional destructive modalities for warts like cryotherapy or laser ablation have some limitations that are excruciating pain during procedure, in especially pediatric patients. Imiquimod is a topical immune response modifier that was approved for treating genital and perianal warts. But, thick stratum corneum of common warts may act as a barrier against drug permeation via the skin. Objectives: To evaluate efficacy and safety of above treatment. Methods: Eleven pediatric patients (6 female and 5 male, mean age 12.5 years) were included in this study. The lesions were treated by fractional 2940 nm Er:YAG laser for achieving the penetration of stratum corneum with 1 or 2 weeks intervals. Then, imiquimod 5% cream was self-applied once daily for 5 days a week. Assessment of response and adverse effects was performed every 2 weeks until complete clearance or up to maximum of 48 weeks. Pain during procedure was checked by VAS (0-10). Results: 8 out of 11 (72.7%) patients experienced complete clearance of all warts lesions. Mean duration of total treatment was 29.7 (16-48) weeks. Mean number of fractional laser treatment was 17.5 (8-37) times. No significant adverse effect was observed. VAS score of the pain during fractional laser treatment was 2.4 (1-4), comparing with 6.2 (5-8) during cryotherapy. Conclusion: Fractional ErYAG laser-assisted topical 5% imiquimod cream is an effective and safe treatment option for recalcitrant common warts of the children do not tolerate pain well.

두부 사측방 촬영술에 의한 건조하악골의 과두영상고찰

조경수,정현대 전남대학교 치과대학 1992 전남치대논문집 Vol.4 No.1

Transcranial radiography has the benefit of providing low equipment cost, and it does not require additional space. The diagnosis of the internal derangement can be made on the basis of the measurement of the joint space by using transcranial radiograph. Thus transcranial radiography is one of the most commonly used radiographic techniques of the diagnosis of TMJ disorders. It is generally known that the transcranial radiograph delineates the lateral third of the condyle. This article intends to help reader understand the morphology of the condylar bony structures through the transcranial radiography. Four radiopaque wire were placed on the condyla surface at intervals of two millimeter from the lateral pole. Using 20 dry mandibles and an Accurad-200 healholder (Denar Corp. U.S.A.). The transcranial radiographs were taken. The results were as follows: 1. The wires that are attached at the distance of 2㎜ from the lateral pole delineate the anterior partition of the condylar outline in the standard and corrected transcranial radiographs. 2. The anterosuperior partition of the condylar outline consists mainly of the image of the wires that are attached at the distance of 2.4㎜ from the lateral pole. 3. The posterosuperior partition of the condylar outline consists mainly of the image of the wires that are attached at the distance of 4.6㎜ from the lateral pole. 4. The posterior partition of the condylar outline consists mainly of the image of the wires that are attached at the distance of 6, 8㎜ from the lateral pole.

21세기를 향한 국가기술자격제도의 발전방안 연구 : New Directions Towards the 21st Century

조정윤,박종성,김현수 한국산업교육학회 1999 산업교육연구 Vol.6 No.-

21세기를 대비한 국가기술자격제도의 발전 방안을 국가 경쟁력 확보 측면에서 모색하기 위해 이 연구에서는 국제 경제 환경 변화에 따른 주요국의 자책제도 대응 방향을 살펴봄으로써 우리나라 국가기술자격제도에 반영해야 할 시사점을 도출하였다. 이와 함께 국가기술자격제도의 운영 실태를 파악하고 자격제도에 관한 요구를 파악하기 위해서 39개 기관을 방문하여 넓은 의미의 국가기술자격 관리자들을 대상으로 면담조사를 수행하였고, 기 국가기술자격 취득자 480명을 대상으로 설문조사를 실시하여 의견을 수렴하였다. 이상의 연구를 통해 21세기를 향한 국가기술자격제도의 발전 방향을 기술·기능 분야의 합리화 방안, 서비스 분야의 합리화 방안, 자격 취득자의 사회적 우대 방안, 자격 정보체제구축 방안, 기초직업능력과의 연계 방안, 민간자격으로 관리·운영의 전환 방안, 국제적 통용성 확보 방안, 통합 국가자격체제 구축 방안으로 나누어서 제시하였다. There are strong links between a nation's economic prosperity, its international competitiveness, and the competency of its population. As international competition intensifies and the rate of economic and technological change accelerates, advanced countries increasingly strive to improve their competitiveness by reforming their national qualification systems. With the advent of the information age and the knowledge- based society, human resource development has become a key factor in determining a nation's competitiveness. And technological qualificatior systems have a direct and significant influence on human resource development. In order to guarantee Korea's continued development as a competitive member of the international community, it is demanded that a Korean Technology Qualification System(KTQS) be established to set Ae nation's future course for the 21st century. Extensive and concrete development plans for KTQS in 21st centry are as follows: First of all, it is essential tc prepare policies for improving the effectiveness and suitability of KTQS and its operations as they apply to the domains of technology and craft. Second, in terms of the service fields, policy measures should be taken to improve and guarantee the diversity of qualification items. Third, appropriate policy measures should be taken in order to raise the general social status of NTQ holders. Fourth, policies should be introduced which will allow for the enhancement of generic competency under the qualification system. Fifth, appropriate policies should be prepared to facilitate a partial transition from a state-run qualification system to a private system. Sixth, with the recent development of international agreements on profession qualifications, it is important to guarantee that Korean qualifications have a common, international currency. Finally, it is imperative that policies be prepared which can establish the necessary foundations for the unification of national qualifications under a single NQ.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

연쇄상구균을 실험감염시킨 넙치치어의 병리조직학적 관찰

조성환,류시윤,김현수,박배근,김덕환,손화영,윤원기,신창호 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

Pathological observations were examined after abdominal inoculation in 7∼8㎝ sized flounder (Paralichthys olivaceus) with 1X10^7 cfu/㎖ of Streptococcus faecalis. The infected flounder were clinically observed and weighed a fish body at 0, 5, 10, 15, 20, 25, 30 days post inoculation. In infected group, mortality were 70% and feed efficiency were 7.2%. In non-infected group, mortality were 10% and feed efficiency were 18.2%. Macroscopically, the significant lesions were characterized by protrusions and opacity of the eyes and ulcer of the caudal pecuncle. Histopathologically, the lesions were observed a degeneration. necrosis and inflammatory cells in muscle of the caudal peduncle and a degeneration and necrosis of the rod cells and detached retina from the black pigmented layer

최근 10년간 마취에 관한 임상적 고찰 (Ⅲ)

조현숙,김윤희,손수창,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the specificity and the historical trends of the anesthetic agents and anesthetic methods used in Chungnam national university hospital, anesthetic experiences of 53,291 in total performed at Chungnam national university hospital from January 1987 to December 1996 were analized statistically and clinically according to age, sex, surgical department, physical status, elective to emergency surgery, premedicants, induction agents, anesthetic methods, main anesthetic agent, anesthetic technique and muscle relaxants. The results were as follows : L The number of cases has been steadily increased in annually. 2. The distribution of the number of patients according to the age were cases 37,309(70.02%) in the group of 13-60 years. 3. There were 27,448 male (51.5%) and 25,843 female (48.5%) cases. 4. 9,208 cases (17.27%) were OB-GY, 9,162 cases (17.19%) in general surgery, 7,936 cases(14.89%) in orthopedic surgery, and 6,079 cases (11.4%) in ENT in order of numbers. 5. According to the ASA classification of physical status , most of the cases were belonged to the class 1 (38.69%) class 2 (40.33%) class 1E (5.52%) class 2E (5.71%). Almost cases were relatively in good physical status. 6. The number of elective to emergency was 7,833 (89.76%), to 5,458 (10.24%) cases. 7. As premedicants, a group of glycopyrrolate (35.20%) was given most frequently. 8. Thiopental sodium has been mainly used for intravenous induction agent. 9. General anesthesia has been used as main method of anesthesia. 10. Enflurane was the most commonly used anesthetic agent. 11. Vecuronium was the most commonly used non-depolarizing muscle relaxant.

면역억제제를 사용치 않은 동소성 간이식 실험견의 조직병리소견

조원현,최순옥,김인호,임태진,김성수,박준희,김우석,김현철,최규택,김진모,권건영 大韓移植學會 1994 Korean Journal of Transplantation Vol.8 No.1

수산물채취 잠수부에서 발생한 중증감압병 37예 분석

조수헌,양대현,최헌 大韓産業醫學會 1989 대한직업환경의학회지 Vol.1 No.1

1986년 12월부터 1988년 11월까지 2년간 지방공사 강남병원 고압산소치료센타에 내원하였던 489명의 감압병환자중 신경계증상 등 중증증상을 보인예는 39명이었다. 이중 수산물채취 잠수작업중 중증감압병에 이환되어 미해군 재가압치료표에 따라 치료가 끝난 37명에 대하여 일반적 특성 및 잠수의학적 특성에 관한 자료를 조사하였다. 중증감압병환자의 67.5%가 25∼34세 연령층에 있었으나 10.8%는 45∼49세의 고연령층 이었다. 1년 미만의 잠수경력을 가진 예가 21.6%이었으며, 잠수기술은 70%가 체계적인 교육보다는 현장에서 잠수작업을 거들면서 기술을 습득하였다. 감압병 발병당일의 잠수형태에서는 31∼50m의 수심에서 2∼8회의 반복잠수 후에 흉부통증 또는 하지감각장애 등의 증상이 나타났는데, 증상발현은 수면부상후 30분이내에 83.7 %가 그리고 3시간이내에 100% 나타났다. 증상발현후 재가압치료를 받기까지의 경과시간은 평균 18시간으로, 재가압치료를 받아 완치된 경우에 있어서는 평균 12일의 입원기간중 11.3회의 고압산소요법을 실시하였다. 중증감압병의 경과 및 회복에는 발생전날의 반복잠수와 주증상발현후 재가압 치료까지의 경과시간이 지연되는 경향을 보였다. Hospital records were reviewed for 486 divers who have been diagnosed as decompression sickness(DCS) at Kangnam General Hospital between December 1986 and November 1988. Among 39 cases classified as serious DCS(type II), the patients had been fishery diving in 97.4% of the cases. The ages of the afflicted divers ranged from 22 to 47 years, with a mean of 31.5% years. The divers were experienced being less than one year in 21.6% and 70% of them learned diving skill by self-taught. In 86.5% of the cases the divers had made multiple divies ranged in depth from 31 to 50 meters. Thirty-one(83.7%) of the patients noted their symptoms within 30 minutes of surfacing. The spinal cord was most often affected, and the most common symptoms were 'numbness' or 'tingling' in one or more extremities and discomfort or pain on the chest. Recompression treatment was delayed for 18 hours in average after the onset of dysbaric symptoms and this treatment is more likely to be effective the sooner that it commences after the onset of dysbaric symptoms.

연마 다듬질 가공면의 표면 미세형상 평가에 관한 연구

조남규,김현국,권기환,한창수,안유민,이성환,박균명 한국공작기계학회 2000 한국공작기계학회 추계학술대회논문집 Vol.2000 No.-

This paper describes the statistical analysis techniques for the surface roughness assessment of polished surfaces. In experiments, the polishing process of the sample surfaces which are manufactured by ball end mill is consist of two steps; the cusp removal process and the surface finishing process. For the cusp removal process, the criterion of cusp removal was established from the power spectrum analysis to assess the change of the cusp removal rate. For the finishing process, the surface was polished by the rotational CBN tool and vibration wood tool. And the surface quality of polished surface was assessed using the functional parameters based on the statistical values of surface profiles. Consequently, the surface finish performance of the polished surface using the vibration wood tool was improved.

Renca 마우스 종양모델에서 지구성운동이 종양형성에 미치는 영향

조정제,안현종,김성수,김창주 대한스포츠의학회 2003 대한스포츠의학회지 Vol.21 No.1

Subcutaneous injection of cells from renal adenocarcinoma line, renca, into Balb/c mice induces fast growing solid tumors. This method has been used to speculate the efficacy of cytokine treatment for tumor regression. The present study was designed to investigate the effect of treadmill exercise on tumor growth using renca mouse tumor model. We also examined the expression pattern of several genes related to immune response after exercise training for 4 weeks. Exercise training reduced the size of tumor mass compared to that of non-exercised group in tumor cell recipient mice. Natural killer(NK) cell activity showed no significant difference between exercised and non-exercised groups in tumor cell non-recipient mice. Although NK cell activity of non-recipients was higher than tumor cell recipients, NK cell activity of exercised group was significantly lower than non-exercised group among tumor cell recipients. There were no significant differences in mRNA expressions of cytokines. scavenger receptors, and neuropeptieds which are related to immune response, while mRNA expression of TGF-beta was significantly reduced both in spleen and in tumor mass by treadmill exercise. Based on the results presented in this study, endurance exercise has shown the possibility to suppress tumor formation.