유아교육실습 지도교사 교육프로그램 개발 연구

윤기영,정현숙,류칠선 서원대학교 교육연구소 2001 敎育發展 Vol.20 No.2

The purpose of this study was to develop a in-service teacher education program for student teaching in early childhood education center in order to reinforce student teacher's educational role for improving their student teaching. In this paper, the sample consisted of 20 early childhood professionals who have experienced at least 3 years in students teaching program. The survey was administered using the Delphi method. The study explored the objectives, contents, administration and method, and evaluation of the developed program. We also attempt to outline the present conditions and problems on student teaching in early childhood education center. As a conclusion, the program have to assist the able kindergarten teacher for understanding student teacher correctly, to consist and administrate a practicum program with systematic support.

충수돌기에 발생한 선암 1예

김칠석(Chil Suk Kim),조남천(Nam Chun Cho),윤광수(Kwang Soo Yoon),김대성(Dae Sung Kim),노병선(Byung Sun Rhoe),조미연(Mee Yoon Cho),양경무(Kyung Moo Yang) 대한외과학회 1995 Annals of Surgical Treatment and Research Vol.48 No.4

경골 천정 골절의 임상적 고찰

서광윤(Gwang Yoon Seo),권칠수(Chil Soo Kwon),김용욱(Young Uck Kim),주석규(Suk Kyu Choo) 대한정형외과학회 1992 대한정형외과학회지 Vol.27 No.1

Colles' 골절 부정 유합의 수술적 치료

고한석,권칠수,서광윤 인제대학교 1984 仁濟醫學 Vol.5 No.3

Most of the Colles' fracture can be achieved a satisfactory clinical result with closed treatment. Eventhough radiographic finding of a malunion and shortening of the radius, the wrist can be expected adequet function with no pain. These result are mainly due to the fact that Collos' fracture occur predominantly in elderly patients who no longer engage in strenous manual activities. Conversely, post-traumatic deformity in young, active patient in less tolerated, especially is those engage in heave manual work. Authors reviewed 12 malunited Collos' fracture treated from January, 1979 to June 1984. Age distribution ranged from 23 to 46. Most frequent cause of injury was a falling from a hight in 11 cases. Corrective osteotomy and iliac bone graft fixing with 2 Kirscher wires was performed in 8 cases including Darrach procedure in 2 cases. The other four cases were performed Darrach procedure only. It took the radiographic bony union after 5 to 10 weeks in corrective osteotomy. Average duration of follow up was 5.2 months. By the modified criteria of clinical evaluation by Fernandez, the result was as follows. In corrective osteotomy there were 3 excellent, 1 good, and 4 fair cases. In Darrach procedure there were 2 fair and 2 poor cases. In young, active patients who engaged in heavy manual work, the malunited Collos' fracture may be cause pain on the wrist due to midcarpal instability. The corrective osteotomy is indicated in selective patient with malunited Colles' fracture who has pain on the wrist. It is mainly for this group of patient that corrective osteotomy of the malunited Colles' fracture should be considered.

Isoniazid에 의한 철적아구성 빈혈 1예

고순희,조미경,윤돈영,박영석,정기석,박근철,류지소,조현찬 대한내과학회 1992 대한내과학회지 Vol.42 No.5

철적아구성 빈혈은 조혈세포의 heme합성의 장애로 저색소성 빈헐, 철적아구 등을 특징으로 하는 질환인데 후천적 원인중 INH는 피리독신 의존성 효소의 길항작용을 하여 철적아구성 빈헐을 일으키는 것으로 알려져 있다. 저자들은 항결핵제로 INH를 사용한 19세 남자 환자에서 이차성 철적아구성 반혈 1예를 경험하였다. 환자는 2주간의 발열을 주소로 입원하였고 늑막삼출 소견이 있어 늑막생검을 하여 결핵성 늑막염 진단하에 INH, pyrazinamide를 포함한 항결핵제 투여를 시작하였다. 4개월후 노작성 호촙곤란과 전신허약을 호소하였고 이학적 소견상 빈혈 소견이 있어 말초혈액 검사및 골수생검을 실시하여 철적아구성 빈혈을 진단하였다. 항결핵제를 끊고 피리독신을 투여하여 철적아구성 빈혈소견은 없었졌고 후에 투여한 pyrazinamide는 철적아구성 빈혈을 일으키지 않았다. 따라서 INH에 의한 철적아구성 빈혈을 진단하였고 국내에서는 첫 예로써 보고하는 바이다. Sideroblastic anemias are diverse hypochromic disorders characterized by hypochromic anemia, ringed sideroblasts in the bone marrow, and ineffective erythropoiesis due to defective iron utilization within erythropoietic cells. Isonicotinic acid hydrazide (isoniazid, INH) is one of the secondary causes of the sideroblastic anemia. We experinced INH-induced sideroblastic anemia in a 19-year old boy with tuberculous pleurisy. The patient was admitted to our hospital because of fever for 2 weeks. The X-ray film of the chest showed pleural effusion on the left side. Tuberculous pleurisy was diagnosed by the pleural biopsy. After four months initiation of antituberculous medications he complained of exertional dyspnea and general weakness. Peripheral blood smear and bone marrow study with iron staining revealed typical sideroblastic anemia. He completely recovered by administration of pyidoxine and withdrawl of INH. Pyrazinamide that is a another possible cause of a sideroblastic anemia did not induce sideroblastic anemia or other hematologic changes in this patient. INH-induced sideroblastic anemia was diagnosed. This is the first case report of INH-induced sideroblastic anemia in Korea.

면양에서 짚 - 계분싸일레지의 영양소 이용율과 무기물의 균형에 관한 연구

이남형,윤칠석,김창원,김춘수 ( Nam Hyung Lee,Chil Suk Yoon,Chang Won Kim,Chun Su Kim ) 한국축산학회 1983 한국축산학회지 Vol.25 No.3

This experiment was carried out to study on the nutrient utilization and mineral balance of straw-manure silage in sheep. Four sheep averaging 40 ㎏ were used in a digestibility and mineral (Ca, P, Na, K, S, Fe, Mg, Cu, Zn) balance trial by 4x4 Latin square design. The four rations tested contained; 1) 4% NaOH treated rice straw-wet layer`s manure silage; 2) 4% NaOH treated barley husk-wet layer`s manure silage; 3) formula feed plus chopped rice straw (50:50 W/W); 4) formula feed plus 4% NaOH treated rice straw-layer`s manure silage (50:50 W/W on the ADM basis). The content of calcium, phosphorus, sodium, potassium, sulfur, magnesium, iron, copper and zinc of layer`s manure were 9.62%, 2.63%, 0.57%, 3.43%, 0.52%, 1.38%, 1300 ppm, 26 ppm and 270 ppm on the dry matter basis, respectively. The content of crude fiber, crude protein, neutral detergent fiber (NDF), acid detergent fiber (ADF), mineral content except calcium in the rice straw-layer`s manure silage and barley husk-layer`s manure silage were similar. Daily dry matter intake, apparent digestibility of organic matter, total digestible nutrients (TDN), digestible energy (DE) or metabolizable energy (ME) in formula feed plus rice straw-manure silage feeding group were significantly improved as compared with other ration feeding group (P$lt;0.01). Digestible crude protein, TDN value, DE and ME of barley husk-:manure silage were determined as 7.46%, 58.21%, 1776 Kcal/ ㎏ and 1456 Kcal/㎏, respectively, while those of rice straw-manure silage were determined as 5.44%, 55.27%, 1356 Kcal/㎏ and 1112 Kcal/ ㎏, respectively. The nutrient availability in formula feed plus chopped rice straw feeding group was significantly decreased as compared with other feeding group (P$lt;0.01). It was observed that positive mineral balance was shown with addition of formula feed to rice straw-manure silage (50:50 W/VW) except of sulfur balance. The formula feed plus chopped rice straw feeding group was in negative mineral balance on essential elements such as phosphorus, calcium, potassium and magnesium. The balance of P, Na, K, Fe, Mg, Cu between rice straw-manure silage feeding group and barley husk-manure silage feeding group was shown similar trend except calcium, sulfur and zinc. Especially, sodium and potassium in both silage was negative balance in spite of higher intake of sodium and potassium due to increase urinary excretion. S/N ratio in rice straw-manure silage, barley husk-manure silage, formula feed plus chopped rice straw or formula feed plus rice straw-manure silage were calculated as 0.09, 0.07, 0.04 and 0.02, respectively. The interaction of sulfur and nitrogen on the utilization of nutrient in this balance trial was not clear but it may be explained a negative balance of sulfur in barley husk-manure silage and formula feed plus rice straw-manure silage feeding group due to the lower S/N ratio as compared with rice straw-manure silage and formula feed plus chopped rice straw feeding group.

자가 슬괵건을 이용한 전방 십자인대 재건술시 경골측 골 터널내 고정의 의의 (이차관절경 검사의 평가)

김영창,서승석,정경칠,곽희철,김윤준,김진석,Kim, Young-Chang,Seo, Seung-Suk,Jung, Kyung-Chil,Gwak, Hey-Chul,Kim, Yoon-Jun,Kim, Jin-Seok 대한관절경학회 2006 대한관절경학회지 Vol.10 No.2

목적: 자가 슬괵건을 이용한 관절경하 전방십자인대 재건술시 이식건의 경골측 골 터널내 고정의 유용성을 이차 관절경 검사의 추시 관찰을 통하여 평가 하고자 하였다. 대상 및 방법: 1999년 12월부터 2005년 5월까지 자가 슬괵건을 이용한 전방 십자인대 재건술을 시행한 환자 중 이차 관절경 검사를 시행한 32례를 대상으로 하였다. 경골측의 고정방법에 따라 나사못 실고정만을 시행한 군(제 1군)과 나사못 실고정과 간섭나사를 이용한 경골측 골 터널내 고정을 함께 시행한 군(제 2군)으로 구분하였다. 이차 내시경 추시 관찰시의 평균 나이는 30세였으며 남자가 30례, 여자가 2례였고 전방십자인대 재건술 후 이차 관절경 검사를 시행한 기간은 평균 21.3개월이었다. 결과는 마취하의 KT-1000 관절계와 IKDC 분석 및 경골측 골 터널의 크기와 Telos 스트레스 부하 검사를 방사선학적으로 평가하였으며, 이차 관절경 소견의 평가 또한 시행하였다. 결과: 평가한 IKDC분석 및 Telos스트레스 부하 방사선 검사상의 전이 정도와 KT-1000 관절계상의 전이정도는 제2군에서 우수한 소견을 보였으나, 통계적으로 의미 있는 차이를 보이진 않았다. 관절 내시경상의 이식건의 긴장도, 이식건의 육안 소견, 이식건의 활액막 증식 정도도 제2군에서 우수한 소견을 보였으나, 통계적으로 의미 있는 차이를 보이진 않았다. 전후면 방사선 사진상 경골측의 골터널의 확장은 제1군에서 2.3 mm 및 제2군에서 1.7 mm로 측정되어 통계적으로 의미 있는 차이를 보였다(P=0.042). 결론: 자가 슬괵건을 이용한 십자 인대 재건술에서 경골측 골 터널내 고정의 부가하는 시술은 경골측 골터널의 확대를 의미 있게 감소 시켰으나 수술 후의 임상적 결과, 관절의 동요 정도, 관절경적 소견에 있어 유의한 차이는 보이지 않았다. 본 연구에서 경골측 고정을 위해 나사못 실고정 단독으로 사용하여도 만족스러운 임상적 결과, 관절의 안정도, 이식건의 성숙을 얻을 수 있었고 경골측 골터널의 확대는 결과에 영향을 미치지 않는다는 것을 알 수 있었다. Purpose: The purpose of this study is to evaluate the effects of intratunnel fixation in the tibial side on the arthroscopic ACL reconstruction with quadruple hamstring tendon at the second look arthroscopy. Materials and Method: From Dec 1999 to May 2005, we arthroscopically reexamined 32 cases who had been done arthroscopic ACL reconstruction with quadruple hamstring tendons. Hamstring tendons of all cases were fixed at femoral side with RigidfixTM. At the tibial side hamstring tendons were fixed only Post-tie (Group I) or Post-tie combined with IntrafixTM (Group II). At the time of second look arthroscopy mean age of cases was 30 years and mean duration for second look arthroscopy was 21.3 months. We analyzed the results with IKDC score, KT-1000 arthrometer under anesthesia, Telos stress radiography, tibial tunnel widening on the radiography and second look arthroscopic findings. Results: Group II had more superior than group I at side to side differences with KT-1000 and Telos stress radiograph, IKDC score, but the differences were insignificant. At arthroscopic evaluation, Group ll also had more superior than group I at graft tension and graft appearance, graft synovialization, but the differences were insignificant. Tibial tunnel widening in the knee AP radiograph was 2.3 mm in Group I and 1.7 mm in Group II and the difference was significant. (P=0.042) Conclusions: Additional procedure of tibial intratunnel fixation in arthroscopic ACL reconstruction with autogenous hamstring tendon significantly prohibited from tibial tunnel widening but clinical results, radiologic joint stability, findings in second look arthroscopy were insignificantly different. We concluded that Post-tie itself induced satisfactory clinical results, joint stability and graft maturation and that tibial tunnel widening did not affect the results.

VDUP1 Is Required for the Development of Natural Killer Cells

Lee, Kee Nyung,Kang, Hyung-Sik,Jeon, Jun-Ho,Kim, Eun-Mi,Yoon, Suk-Ran,Song, Hyunkeun,Lyu, Chil-Youl,Piao, Zheng-Hao,Kim, Sun-Uk,Han, Ying-Hao,Song, Su-Sung,Lee, Young-Ho,Song, Kyu-Sang,Kim, Yong-Man,Y Elsevier 2005 Immunity Vol.22 No.2

<P><B>Summary</B></P><P>Vitamin D<SUB>3</SUB> upregulated protein 1 (VDUP1) is a stress-response gene that is upregulated by 1,25(OH)<SUB>2</SUB>D<SUB>3</SUB> in tumor cells. The in vivo roles of VDUP1 were investigated by producing mice lacking VDUP1 (VDUP1<SUP>−/−</SUP> mice). VDUP1<SUP>−/−</SUP> mice showed minimal changes in the development of T and B cells, but there was a profound reduction in the numbers of natural killer (NK) cells. As well, these mice showed decreased NK activity. In the VDUP1<SUP>−/−</SUP> mice, the expression of CD122 was reduced, demonstrating that VDUP1 is required for CD122 expression and NK maturation. In addition, severe lymphoid hyperplasia in the small intestine was observed in VDUP1<SUP>−/−</SUP> mice. Taken together, these results suggest that VDUP1 is a critical factor for the development and function of NK cells in vivo.</P>

아이트랙킹을 통한 효과적 스토리텔링

임찬(Lim Chan),최규호(Choi Kyu-ho),김완석(Kim Wan-suk),윤재선(Yoon Jae-sun),민병철(Min Byung-chil),백로라(Baek Ro-ra) 한국디자인학회 2010 디자인학연구 Vol.23 No.4

한국의 발톱진균증 환자의 삶의 질에 관한 연구

조백기,박종갑,김형옥,김성욱,백승철,김진우,김시용,안규중,전재복,오지원,김낙인,이규석,오칠환,김수남,김상태,손숙자,신용우,김동석,이원우,권경술,서대헌,황규왕,이종석,고재경,강원형,정기양,최응호,김기홍,박석돈,강승주,함정희,명기범,김방순,구상완,김병수,원영호,김한욱,송은섭,정병수,노병인,홍창권,박장규,한지윤,김광중,구대원,김종민,김재홍,유희준,양경미 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2

Background: Onychomycosis, especially toenail onychomycosis has become one of the common fungal infection and has historically been regarded as a cosmetic rather than medical problem by many patients, even by physicians. Recently, however, there are several reports that is a refractory disease which may cause a deleterious effect on patiets quality of life (QOL). Objective: The purpose of this study was to investigate the impact of toenail onychomycosis on QOL in Korea and to assess the chandes of QOL after treatment. Methods: Total 1004 patients with toenail onychomycosis which was confirmed by clinical findings and KOH preparation were were enrolled at 47 dermatologic centers in Korea, and interviewed with standardized QOL questionnaire before and after sytemic antifungal treatment. Responses to the questionnaire were scored by 5-point scale (1∼4) and averaged, and were analyzed for 5 dimensions of emotional impact, social impact, symptorn and functional impact, patients views concerning treatment, and relationship with doctor. Results: 1. Before and after treatment, the most serious impact was emotional dimension showing 1.90 and 1.30 in average score (AS), and social (AS: 1.14 and 0.83) and symptom and functional impact (AS: 1.05 and 0.92) was also affected. 2. In female rather than male, statistically more significant impact on patients QOL was observed in all dimensions. 3. After treatment, 3 of 5 dimensions were improved significantly - emotional dimension (AS : from 1.90 to 1.30), social dimension (AS: from 1.14 to 0.83), patients view concerning treatment (AS: from 1.34 to 1.02). 4. The drgree of patients satisfaction at the therapeutic effect was very high- 62.4% (immediately after treatment) and 65.8% (9 months affer initiation of treatment) of patients answered excellent or good. Conclusion: This study confirms that toenail onychomycosis has significant impact on the overall QOL of patients. Also the effect of antifungal therapy on patients QOL were watisfactory. Therefore, both doctor and patient should pay more attention to the treatment of onychomycosis. [Kor J Med Mycol 3(1): 115∼124]