비전형적 임상증상을 나타낸 환상육아종 1 예

노병인,장진요,노병관,최문섭 대한피부과학회 1982 大韓皮膚科學會誌 Vol.20 No.2

Granuloma annulare is a benign, usually self-limited chronic dermatasia of unknown cause, charaeterized by akin colored papules that may be arranaged in an annular configuration. Histopathologically, it is charicterized by camplete or incomplete foeal degeneration of collagen of chronic infliammatory cells. The authors obaerved an atypical case of granuloma annulare in a 4-year-old girl. She showed multiple papules and nodule on hands and feet. On inital examination, her skin lesions suggested histiacytosis, xanthanulama, rheumatoid nodule, or benign skin tumor. But the skin biopey revealed typica1 findings of granuloma awulare. Focal degeneration of colagen was confirmed by toluictine blue stain. Her skin lesions were almoatly cleared by skin biopsy and intralesional injectian of corticosteroid.

제40차 춘계학술대회 : Symposium 연제 ; 피부질환의 치료 : 항 진균제 ; 경구용 항진균제

노병인 대한피부과학회 1988 초록집 Vol.26 No.20

잊혀지지 않는 환자

노병인 중앙대학교 1979 無影燈 Vol.4 No.1

피부 편평세포암과 기저세포암에서 각질형성세포 성장 인자 mRNA의 발현

노병인,홍창권,황규광,서성준,천태종 대한피부과학회 2000 대한피부과학회지 Vol.38 No.3

Background:Human keratinocyte growth factor(KGF) is an epithelial cell specific mitogen which is secreted by normal stromal fibroblast. In skin, KGF has been shown to stimulate keratinocyte proliferation. Objective:In the present study, we sought to determine whether KGF is expressed in human squamous and basal cell carcinoma. Methods:Using a reverse transcriptase polymerase chain reaction(RT-PCR), we examined the expression of KGF mRNA in normal and cancerous human skin tissues. Results: 1. The 583 bp KGF specific PCR product was observed in normal human cultured fibroblast, but no PCR product was seen in normal human cultured keratinocyte, A431, PAM212, HaCaT, and XB2 cell lines by RT-PCR of KGF mRNA using KGF-specific primer as visualized on an ethidium bromide stained agarose gel. 2. The 583 bp KGF specific PCR product was observed in the normal human dermis, squamous and basal cell carcinoma samples. 3. All three squamous and basal cell carcinoma samples revealed significant overexpression of KGF mRNA transcript in comparison with normal skin tissue. Conclusion:These results suggest that KGF mRNA level may be elevated in squamous and basal cell carcinoma and elevated KGF may enhance cellular proliferation of these skin carcinoma.

자원봉사영역이 정부능력에 미치는 영향

盧炳一(노병일) 서울행정학회 1996 한국사회와 행정연구 Vol.7 No.-

제55차 추계학술대회 및 총회 : 심포지엄 5 ; 모발 : 소아 원형 탈모증의 임상적 고찰

노병인 대한피부과학회 2003 초록집 Vol.41 No.20

탈모증

盧炳寅 대한의사협회 1999 대한의사협회지 Vol.42 No.7

아킬레스 프로젝트 : 계절에 따른 발 질환 발병율과 환자의 복용 순응도 평가를 위한 역학조사 An Epidemiology Survey to Assess the Seasonal Incidence of Foot Diseases and Patient Compliance

노병인,양경미 대한의진균학회 1999 대한의진균학회지 Vol.4 No.1

Background: Dermatological diseases affecting the feet, e.g. fungal infections and nail infections, are often not fully perceived as real medical problems even when they experience great discomfort, including pain. These misperception often prevents from seeking timely treatment, which can result in very severe conditions. This survey, so called "ACILLES PROJECT" was a "foot screening” project that would be focused on all parts of the body below the Achilles heel: foot, toe and toenails. Objective: This study was undertaken for both medical doctors and patients to raise the awareness of foot diseases and additional insights into disease that could affect foot. And also, in seasonal variation, we tried to compare the epidemiological data and to look over the relationship of dermatophytosis in other parts with fungal infections in foot and to analyze the compliance and efficacy of antifungal agents in the treatment of patients who were diagnosed as dermatophytosis in their feet in the treatment of antifungal agents. Methods: Achilles survey was conducted for one week from 7^th July to 13^th July, 1997 and 16^th March to 17^th April, 1998 co-worked by the Korean Society for Medical Mycology and Janssen Korea. In 1997, 19,298 patients, who visited dermatology and urology, and 353 investigators participated in this survey. And Achilles 98, in 1998, was composed of two parts, Unit I and Unit ll. Unit I survey was a foot disease consult program and Unit Ⅱ was a patient compliance survey. 29,922 patients, 391 investigators and 16,383 patients, 350 investigators were involved in Unit I and Unit Ⅱ respectively. Results: Among total 29,922 patients who responded to the survey, 57.7% of them had more than one foot disease. There was no big difference comparing with the number (67%) in the survey of last summer. And it was observed that fungal infection was the most dominant disease (79.8%) regardless of seasons (83.7% in July, 1997). Furthermore, there were no significant differences in the prevalence of other foot diseases for each season (eczema 11.1%, corns 5.1%, warts 2.7%, 2.1%). Oral antifungal agents were prescribed to the patients who were diagnosed as having fungal infections in their feet in order to survey drug compliance by filling out the patients' diary. In compliance, only 24% of patients in itraconazole pulse therapy for 7 days and 16% of patients in itraconazole continuous therapy for 28 days compiled with their dosage guideline exactly. It is observed that the longer the duration of drug therapy is, the worse the patients' compliance is. Conclusion: According to the epidemiological survey in 1997 and 1998, the prevalence of foot disease was not significantly different seasonally, and it was reported that the awareness of and the intention for the treatment of foot diseases were not high enough based on the compliance data of patients.

우췌상 피부결핵 1예

노병인,홍창권,서성준,전병환 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.1

Tuberculosis verrucosa cutis is caused by the external inoculation of Mycobacterium tuberculosis into the skin of a person who already has a significant degree of cell mediated immunity to this organism. This form of cutaneous tuberculosis is less common. A 29-year-old male had a solitary adult palm sized, verrucous surfaced scaly plaque for about 10 years. The lesion was excised about 10 years ago but gradually increased in size. At first we suspected a deep mycosis and treated him with anti-fungal medication for 3 months. However, the skin lesion did not improve. He was then treated with anti-tuberculosis medication for 9 months under the impression of tuberculosis verrucosa cutis. The skin lesion was almost healed and no recurrence has been observed for 8 months after the treatment.

저비용 초소형위성 개발 위한 시스템 엔지니어링 프로세스의 최적화 방법

노병인,소승섭,최종권,유동서,장영근 한국항공우주학회 2011 한국항공우주학회 학술발표회 논문집 Vol.2011 No.4

초소형위성은 기존의 대형위성과 다르게 저비용으로 단기간에 개발이 가능한 장점이 있어, 세계 여러 대학에서도 정보를 공유하며 연구가 활발히 진행되고 있다. 하지만 초소형위성에 최적화된 시스템 엔지니어링 프로세스가 없어 대형위성의 시스템 엔지니어링 프로세스를 적용하다 보니 불필요한 과정으로 인해 개발기간과 비용이 증가되어 대학에서 연구하기에는 위험 부담이 클 수밖에 없다. 따라서 초소형 위성에 맞도록 위성 시스템 엔지니어링 프로세스를 최적화함으로써 대학에서도 자체 프로그램으로 진행하기에 적합하고, 학생들에게도 시스템 개발과정을 직접적으로 경험을 할 수 있게 하여 실질적인 경험을 가진 위성 전문가를 양성하기에 적합하다. 그리고 최근 들어 각광을 받고 있는 다학제간 시스템 교육의 활성화를 이룰 수 있다. Ultra-small satellite, unlike Large-satellite used previously, has a strong point in case of low-cost and short period when developing. So many universities around the world are now sharing their information and doing their research. However, we use system engineering process of large satellite because there is no proper system engineering for ultra-small satellite, That makes the university burden on the increase in cost and period. However, we optimize satellite system engineering for ultra-small satellite so that university can develop their own program and students can experience the process of system development both directly and indirectly. It is appropriate that we can train the satellite experts who have the real experience and make the multidisciplinary system activated which is recently focused on.