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함정희 梨花女子大學校 韓國生活科學硏究院 1992 韓國生活科學硏究院 論叢 Vol.50 No.-
Psoriasis, which affects 3% of the outpatients in Republic of Korea, is a common, chronic, recurrent, inflammatory disease of the skin characterized by rounded, circumscribed, erythematous dry scaling patches of various sizes, covered by grayish white or silvery white, imbricated and lamellar scales. The lesion in ordinary cases have predilectin for the scalp, nails, extensor surfaces of the limbs(especially the shins), the elbows, the knee, and the sacral region. The histologic picture of psoriasis vulgaris varies considerably with the stage of the lesion and near the margin of advancing plaques. In the fully developed lesions of psoriasis, as best seen at the margin of enlarging plaques, the histologic picture is characterized by (1) regular elongation of the rete ridges with thickening in their lower portion (2) elongation and edema of the papillae (3) thining of the suprapapillary portions of the stratum malpighii, with the occasional presence of granular cells (4) the absence of granular cells (5) parakeratosis (6) the presence of Munro microabscesses The purpose of this study is to evaluate pathophysiology of psoriasis observing the morphological changes of corneocytes in the epidermis by scanning electron microscope(SEM). All materials were taken from involved skin of six psoriatic patients, uninvolved skin of six psoriatic patients, six normal persons and treated psoriatic lesions by skin surface biopsy. The results were as follows : 1. There were no folding lines or microplications in the involved skin of psoriatic patients compared with stratum corneum of normal person. 2. There were more profuse villi and more prominent villous projections in the involved skin than uninvolved skin of psoriatic patients. 3. There were no villi in the corneocytes except a few in normal person. 4. Profuse villi and less prominent villous projections were seen on the treated psoriatic lesions without scales.
항암요법을 받는 간암환자의 불안, 오심, 구토에 대한 발반사마사지 효과 : 간동맥화학색전술 중심으로
함정희,이중분,김복희,강종순,오윤주,권은자,진영경,성숙경,강유경,주명순 병원간호사회 2003 임상간호연구 Vol.8 No.2
The purpose of this study was to examine the effects of foot reflexology on anxiety, nausea and vomiting in patients with hepatocellular carcinoma transarterial chemoembolization. Sixty patients with hepatocellular carcinoma transarterial chemoembolization participated in the study. Two groups consisted of subjects assigned : one experimental group(30 patients), and the other the control group(30 patients). All subjects were admitted for inpatients transarterial chemoembolization at the A medical center between May 10 to July 20 in 2002. A research study in which a twenty- minutes foot reflexology was offered on three-consecutive to 30 patients with hepatocellular carcinoma chemotherapy as a anxiety, nausea and vomiting reduction in intervention described. A quasi-experimental control- group pretest- posttest design was used to collect data before and after the intervention. The method for assessing nausea and vomiting was the Index of Nausea and Vomiting by Rhodes et al and that for anxiety was State-Trait Anxiety Inventory by Spielberger. The objective physiologic measures of blood pressure and pulse rate were obtained before and after intervention. Analysis was done by a real number and percentage, chi-square test, Chronbach's α, t-test and peason's correlation coefficients. The results of this study were as follow : 1. Experimental group will reduce a state- trait anxiety the administration of foot reflexology than control group. The research hypothesis was supported(p=.000). Experimental group will be lower a VAS the administration of foot reflexology than control group. The research hypothesis was supported(p=.000). Experimental group will be lower a Systolic blood pressure the administration of foot reflexology than control group. The research hypothesis was supported(p=.004). Experimental group will be lower a diastolic blood pressure the administration of foot reflexology than control group. The research hypothesis was supported(p=.031). Experimental group will be lower a pulse rate the administration of foot reflexology than control group. The research hypothesis was supported(p=.050). All of the first research hypothesis was supported. 2. Experimental group will reduce a nausea and vomiting the administration of foot reflexology than control group. The second research hypothesis was supported(p=.000). In condition, foot reflexology is a effective intervention that reduces anxiety, nausea and vomiting in patients with hepatocellular carcinoma transarterial chemoembolization.