젊은 성인에서 흡연에 의한 상완동맥 내피기능의 부전에 관한 연구

이상철,권영주,방덕원,이선해,이보영,김지욱,김영훈,온영근,현민수,김성구 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Background and Objectives : Cigarette smoking is a major factor and the most modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherosclerosis, before the structural change of the systemic arteries. We hypothesized that endothelial dysfunction might be present in the systemic arteries of young adult smokers and that this might be dose-dependent phenomenon. Therefore, we try to certify that smoking is associated with endothelial dysfunction in healthy young adults without other risk factor of atherosclerosis. Subjects and Methods : we studied noninvasively 29 subjects aged 3 to 4 decades without other risk factor of atherosclerosis, they were composed of the two groups, current smokers(n=15) and nonsmokers(n=14). Smoking history varied from 3 to 20 pack years. Using high-resolution ultrasound, vessel diameter and mean flow rate were measured at rest, during reactive hyperemia(with flow-mediated endothelium-dependent dilation), and after sublingual nitroglycerin(NG-induced endothelium-independent vasodilation). Result : Flow mediated endothelium dependent dilation was observed in the control subjects (9.4±3.44%) but was impaired in the smokers(5.8±2.51%)(p=0.004). NG-induced endothelium independent dilation is no difference in all subjects. Conclusion : Cigarette smoking is associated with endothelial dysfunction in healthy young adults.

Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

청소년 인터넷 중독 검사 방법의 통계적 고찰 및 개선 -Young의 척도를 중심으로

박찬정 ( Chan Jung Park ),김형철 ( Hyung Chul Kim ),고영민 ( Young Min Ko ),현정석 ( Jung Suk Hyun ),김철민 ( Cheol Min Kim ) 한국컴퓨터교육학회 2010 컴퓨터교육학회 논문지 Vol.13 No.4

국내외에서 이루어진 기존의 인터넷 중독 검사에 대한 연구는 다양하며 방대하지만, 대부분의 연구가 중독도 검사를 위한 항목추출이거나 항목들을 이용한 중독도 분석이었지 항목간의 분석을 통한 차별화는 이루어지지 않았다. 본 논문에서는 리즈렐과 데이터마이닝 기법을 이용하여 Young의 인터넷 중독 검사방법을 고찰하고 문제점을 지적한 후, 검사 방법에 대한 대안을 제안한다. 이를 위해 Young의 척도를 이용하여 청소년 440명을 대상으로 설문을 실시하고, 요인분석을 통해 Young 척도의 문제점을 분석한다. 또한, 데이터 마이닝 알고리즘인 J48 및 PART를 이용하여 설문문항들 중에서 인터넷 중독도를 구분 지을 수 있는 항목들을 선별하고 이를 기반으로 인터넷 중독 학생들을 진단하고 처방하는데 활용하는 방법을 제안한다. So far, the researches about the Internet addiction testing are diverse and enormous. However, since the testing factors have the same importance, there is no discrimination among the factors. In our paper, we analyze the problems of the existing researches by using Lisrel and data mining algorithms. Next, we propose an alternative for the Internet addiction testing. In order to accomplish these, we make an questionnaire consisted of Young`s test and then, we asked to 440 primary and secondary school students. In addition, we analyzed the problems of Young`s test with factor analysis and then, we distinguish more important items from others with J48 and PART. Finally, based on this analysis, we propose a method to diagnose addicted students and prescribe them.

부산·울산·경남지역 직업병 감시체계

김정일,김병권,김정원,채창호,이철호,강동묵,김지홍,김진하,김영욱,이영하,이지호,김정호,윤형렬,유철인,정백근,장태원,김운규,윤동영,강진욱,김종은,안진홍,이동준,장준호,이광영,송혜란,최영희,이용환,조병만,최홍렬,고상백,김은아,이유진,홍영습,정갑열,김정만,김준연 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

Objective: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases Methods: l l hospital participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted. Results: Between April 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. most of the HAVS cases came from shipbuilding, and 172 of them (92.7%) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9%). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6%) and 4 (12.1%) cases of occupational asthma, the agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10(58.8%) of the cases were diagnosed as squamous cell carcinoma and 5(29.4%) as adenoma. Conclusion: This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.

A simple approach to estimate the mechanical properties of collagen-like microfibrils surrounded by water

Young-june Yoon,Cheol-soo Bae,Ho-sik Park 한국멀티미디어학회 2010 한국멀티미디어학회 국제학술대회 Vol.2010 No.-

The effective Young's modulus of a microfibril surrounded by water may be simply calculated by using the upper (Voigt) and lower (Reuss) bounds. The result is compared to the Young's modulus estimated by using the Steered Molecular Dynamics (SMD) (Zhang et al. 2007). Our result shows 9.2% difference from the result estimated by SMD, but the steps using these bounds are much simpler than SMD..

蒼耳子의 IC - 2 細胞에 대한 抗알러지 效果에 關한 硏究 ( 2 )

徐榮培,崔永奉,李龍求,李永喆 대한본초학회 2002 大韓本草學會誌 Vol.17 No.1

This study was carried out for the purpose of knowing the effect from anti-allergic action of B cells and the IC-2 mast cells the extraction from Xanthii Fructus(EXF). In order to know the effect of the cytotoxicity from extraction of Xanthii Fructus, we had to examine the safe density of EXF on lung fibroblast cells of the mouse (mLPCs). We also attempted to resolve the relationship cytotoxicity. The effect was on the organization of cytokine gene expression from the increas and divorce of the B cells and allergic acting by EXF, we found it necessary to examine the IC-2 cells and B cells. We examined the histamine release of IC-2 cells by ELISA method, we also examined the effect of EXF on the increase and divorce of the B cells by ^3H-thymidine uptake method. We then analyzed the release of IL-4, IgE and nitric oxide (NO). The results are as follows : 1. EXF did not show cytotoxicity against mLFCs. 2. According to the inspection on the effect on IC-2 cells gene expression by EXF, we found out the following results: EXF reduced IL-4, IL-6, GM-CSF, TNF-α gene expression and histamine release of IC-2 cells. The EXF inhibited signs of inflammation IC-2 cells.

POSCO Smart Factory의 핵심역량 분석: VRIO 모형을 중심으로

최영철(Choi, Young-Cheol),박현준(Park, Hyunjun) 한국경영교육학회 2020 경영교육연구 Vol.35 No.6

[연구목적] 본 연구에서는 제조환경의 패러다임 변화 속에 새로운 성장동력으로 스마트 팩토리를 도입한 기업의 경영자원을 분석하여 핵심역량을 파악하고 기업 전반에 미치는 영향을 진단, 시사점을 제공하고자 하였다. [연구방법] 2015년 이후 스마트팩토리를 도입한 포스코를 연구대상으로 선정하고, 자원기반관점에 의거 기업 내부역량 분석에 유용한 VRIO Framework를 통해 스마트팩토리에 영향을 받은 경영자원 분석과 핵심역량을 도출하였다. 또한, 이 핵심역량이 경영성과에 어떠한 영향을 미치는지에 대한 부분도 검토하였다. [연구결과] 포스코 스마트팩토리의 영향을 받은 경영자원을 VRIO 분석한 결과 7개 핵심역량을 도출하였고, 이 핵심역량의 효과로 생산성 향상, 설비고장 비가동율 최소화, 불량률 및 품질 실패비용 감소, 납기준수율, 생산계획 증대로 인한 에너지 비용 절약 등을 통해 재고비용 합리화, 매출액 증대, 비용 절감을 통한 이익 증대, 부가가치 창출, 기업의 가치 극대화 등의 재무적 성과도 거두고 있음을 확인하였다. [연구의 시사점] 스마트팩토리의 도입은 기업이 지속 가능한 경쟁우위를 갖게 하여 핵심역량으로 발전시키며 기업의 성과에 큰 역할을 하지만, 각 기업만의 고유 특성을 고려하여 기업의 대내외자원과 기업의 주변 환경을 결합한 실증연구도 필요하다. [Purpose] In this study, we tried to analyze the management resources of companies that introduced smart factories as new growth engines amid a paradigm shift in the manufacturing environment to identify core competencies, diagnose their impact on the enterprise as a whole, and provide implications. [Methodology] Through VRIO Framework, management resource analysis and core competencies affected by POSCO Smart Factory were derived. It also considered how these core competencies affect management performance. [Findings] The analysis of the management resources affected by POSCO Smart Factory resulted in seven core competencies. It confirmed that the effects of these core competencies have also resulted in financial performance, such as rationalizing inventory costs, increasing sales, creating value-added, and maximizing corporate value. [Implications] The introduction of smart factories plays a significant role in companies’ performance by making them have a sustainable competitive advantage and developing them into core competencies. Still, it is also necessary to conduct empirical studies that combine the companies’ internal and external resources with the environment surrounding.

圓光醫大 附屬 第2病院 神經精神科 患者에 對한 統計的 考察(Ⅱ)

박민철,장광철,김상원,김한주,유미경,김훈,유용진,김현정,박남진,오상우,이귀행,노승호,백영석 圓光大學校 醫科大學 神經精神科學敎室 1992 圓光精神醫學 Vol.8 No.1

본 연구는 1986년 7월 11일부터 1991년 7월 10일까지 원광의대 부속 제2병원 신경정신과에서 의래 및 입원치료를 받았던 6,072명의 환자를 대상으로 병원 역학조사를 실시하고 그 결과를 1차조사 (박민철 등1986)와 비교했다. 1.전체 환자 중 남자가 54.4%로 여자보다 많았고, 이리와 이리 인접지역이 84.0%로 대부분의 지역을 나타났다. 의료보장상태는 보험환자가 57.1%, 의료보호환자21.8%, 일반환자 21.1%였으며 연령별로는 20대 24.6%, 30대 22.8%로 20대 30대가 절반정도를 차지했다. 2.외래환자에서는 신경중성장애가 46.0%로 가장 많고 정동장애, 경련성장애 순이며, 입원환자에서는 정신분열증이 30.5%로 가장 많고 기질성정신장애, 정동장애의 순이었다. 3.남자는 신경증성쟝애(23.4%), 정신분열증, 기질성정신장애 순이고 여자는 신경증성장애(39.9%), 정동장애, 정신분열증의 순이었다. 남자가 여자보다 많은 진단은 알코올정신장애(94.6%), 기질성정신장애, 소아정신장애 순이고, 여자가 남자보다 많은 진단은 정동장애(64.5%), 신경증성장애였다. 4.진단별 연령분포에서 신경증성장에는 30대(25.3%), 20대, 40대 순이고, 정신분열증은 20대(40.5%), 30대, 40대 순이며, 정동장애는 20대, 30대, 50대 순이나 비교적 비슷한 융이었다. 5.진단별 발병연령에서 신경증성장에는 20대, 30대가 절반이고,정신분열증은 20대(51.3%), 10대, 30대 순이며 정동장애는 20대(30.7%), 30대, 50대 순이었다. 진단별 평균 발병연령은 신경증성장애 32.7세, 정동장애 36.1세, 정신분열증 23.6세였다. 6.진단별 이병기간은 2년이상이 신경증성장에 28.3%, 정신분열증 68.5% 정동장애 43.9%인데 전체적으로 41.0%였다. 진단별 평균 이병기간은 정신분열증 73.2개월, 정동장애 45.5개월, 신경증성장애 29.5개월이었다. We examined epidemiologic study of 6,072 patients who visited Wonkwang Neuropsychiatric hospital since July 11 of 1986 until July 10 of 1991 and compared this results with previous study(Park et al 1986). The study revealed as follows:1. Of total patients males visited this hosptial more than females as 57.1%, Most of them(84.0%) resided Iri and neighbouring Iri. In the point of insurance, insured patients, medicaid patients and uninsured patients were 57.1%, 21.8% and 21.1% respectively. On the distribution of age, the twenties, the thirties were 24.6%, 22.8% respectively and twenties and thirties were about half of total patients. 2. Of outpatients neurotic disorder was the most as 46.0%, secondly mood disorder and thirdly convulsive disorder, but of inpatients schizophrenia was the most as 30.5%, secondly organic mental disorder and thirdly mood disorder. 3. Of males neurotic disorder was the most as 23.4%, secondly schizophrenia, and thirdly organic mental disorder, but of females neurotic disorder was the most as 39.9%, secondly mood disorder and thirdly schizophrenia. alcoholic mental disorder(94.6%), organic mental disorder, child mental disorder were mostly found in males,but mood disorder(64.5%) and neurotic disorder were mostly found in females. 4. On the distribution of age neurotic disorder was found the most in the thirties(25.3%), next in the twenties and in the forties, and schizophrenia was found the most in the twenties(40.5%), next in the thirties and in the forties, but mood disorder was found the most in the twenties, next in the thirties and in the forties but revealed similar rates relatively. 5. On the distribution of age of onset neurotic disorder developed nearly half during the twrnties and the thirties, schizophrenia developed mostly during the twenties (51.3%), secondly the teens and thirdly the thirties, but mood disorder developed firstly the twenties(30.7%), secondly the thirties and thirdly the fifties. on the average age of onset of illness neurotic disorder, mood disorder and schizophrenia were 32.7 years, 36.1 years and 23.6 years respectively. 6. On the duration of illness more than two years was 28.3% in neurotic disorder, 68.5% in schizophrenia and 3.9% in mood disorder and on the average duration of illness schizophrenia, mood disorder and neurotic disorder were 73.2 months, 45.5 months and 29.5 months respectively.

울산 지리정보 시스템

옥철영,김영철,조정관 울산대학교 1997 공학연구논문집 Vol.28 No.2

지리정보 시스템은 수치화된 지리데이타를 화면으로 mapping시키고, 지리테이타와 그의 속성정보를 연계시킬 수 있는 초보적인 기능이 필요하다. 본 논문에서는 이러한 기능을 가진 지리정보 시스템을 구현하기 위한 방법을 제안하였다. 그리고 실제 울산시의 수치지도를 제작하고 업종별 전화번호부를 데이타베이스화하여 울산 지리정보 시스템을 구현하였다. 울산 지리정보 시스템은 수치화된 지번데이타와 업종별 전화번호부의 주소를 연계시켜, 질의된 해당 시설물이나 상호의 주소 위치를 지리테이타와 함께 화면으로 mapping시키는 지리정보 시스템의 응용 프로그램이다. GIS(Geographic Information System) needs two fundamental functions : a mapping function which maps a vetorized geographic data to screen and a relating function which associates the geographic data with their attribute information. This paper proposes a method to design the GIS which has the fundamental functions and implements an Ulsan GIS(UGIS). The UGIS consists of a vectorized Ulsan geographic data and a telephone database of business category. The UGIS associates a lot number in the Ulsan geographic data with an address in the telephone database, and maps an address of major building or a name of business queried to screen with the Ulsan geographic data.

심부전 백서의 대동맥과 폐동맥에서 보이는 C형 이뇨단백에 대한 이완반응의 이상

김철호,김광일,조영석,조주희,오병희,이명묵,박영배,최윤식,이영우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8