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Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea
공동주택의 장수명화 및 재생을 위한 IHCS 표준모델 개발 : 개념 및 특성을 중심으로 With a focus of Concept and Character
최경석,강재식,양관섭,이승언 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
Recently Excessive national resources, energy losses and social·economical problems are induced by reconstruction apartment housing which was constructed about 20 years and is enough to keep one's residence structurally. Especially, the greatest obstruction in longevity & recycling technology of apartment housing is the current Ondol system of wet process integrated structures. Also the current Ondol system is difficult to improve due to its character of material and process. The object of this study is to develop IHCS(Infill Heating & Cooling System) standard model with prefabricated & dry process that shall be the substitution for the current wet Ondol system.
아동의 사회적 문제해결능력과 어머니의 대화형태와의 관계연구
김재림,백은주,신유림,심미경,이혜경 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-
The present study investigated the relationship between the social problem solving ability of children and the language patterns of their mothers. The subjects included 193 nine yearolds (185 girls, 108 boys), and 230 twelve yearolds (115 girls, 115 boys). The instruments used were a language patterns test for the mother and IPA (Interpersonal Problem Solving Ability Test) for children. Major finding from this study were: ⑴ the correlation between the social problem solving ability of children and the language patterns of their mothers was not statistically significant, ⑵ the language patterns of the mothers were significantly different by child's sex; for boys, mother used more ordered language patterns and for girls, mothers used more ordered language patterns and for girls, mothers used more humanoriented language patterns, ⑶ the social problem solving ability of children were significantly different by child's age; 12yearolds exhibited higher ability than 9yearolds.
견/합성섬유 혼방품의 1욕염색(Ⅶ) : 견/아크릴로니트릴 섬유 혼방품의 염색거동 Adsorption Behavior of Silk/Acrylonitrile Fiber
金公朱,김경수,전재홍,이화선 全北大學校 1995 論文集 Vol.40 No.-
In one bath dyeing system of silk/acrylonitrile(acryl) fabric with acid/disperse dyes and acid/cation dyes, adsorption behavior of acid dyes, disperse dyes and cation dyes on silk and acryl fabrics were examined. In the dyeing of acryl with the C. I. Disperse Red 19(Red 19) and The C. I. Disperse Red 60(Red 60), dye uptake with Red 19 was higher than that with Red 60. When the silk and acryl fabric were dyed with C. I. Basic Red 27(Red 27), dye uptake on the acryl was higher than that on the silk. When the silk/acryl fabric was dyed with Red 19 and Basic 27, solid shade could be obtained with Red 19 but could not be obtained with Basic 27. In the dyeing of silk/acryl fabric dyed with Blue 80/Red 27 and C. I. Acid Blue 113(Blue 113)/C. I. Basic Blue 116(Blue 116), compatibility could be obtained with Blue 80/Red 27 but that could not be obtained with Blue 113/Blue 116.

( Jae-gyoung Gwon ),( Dan-bee Lee ),( Hye-jung Cho ),( Sun-young Lee ) 한국목재공학회 2018 목재공학 Vol.46 No.5
Cellulose acetate (CA) has been widely utilized for composite materials due to its high transparency and thermal resistance. In this study, CNCs (cellulose nanocrystals) were reinforced in CA nanocomposites for fortifying mechanical properties of the composites. In addition, CA nanocomposites reinforced with CNCs were manufactured by extrusion/ injection processes applied with CNC-predispersion method for achieving a high dispersion level of CNCs in the CA matrix. According to the analysis of mechanical properties, the CA nanocomposite with 3 wt% CNCs has the highest tensile and flexural strengths due to the reinforcing effect of CNC nanoparticles. Thermogravimetric analysis (TGA) showed that the addition of acid hydrolyzed CNCs slightly lowered the initial pyrolysis temperature of CA nanocomposite.


Gene Expression Analysis of Anticancer Drug Induced Hepatotoxicity Using cDNA Microarray
Lee, Gyoung-Jae,Kim, Yang-Suk,Jung, Jin-Wook,Hwang, Seung-Yong,Park, Joon-Suk,Kang, Kyung-Sun,Lee, Yong-Soon,Chon, Man-Suk,Chon, Kum-Jin,Kang, Jong-Soo,Kim, Dong-Hyean,Park, Young-Keun The Korean Society of Toxicogenomics and Toxicopro 2006 Molecular & cellular toxicology Vol.2 No.2
Tamoxifen (TAM), a non-steroidal anti estrogen anticancer drug and chemopreventive agent for breast cancer, have caused cholestasis in liver. The potent hepatocarcinogenicity of this drug has been reported. Methotrexate (MTX) is dihydrofolate reductase inhibitor which interfaces with the synthesis for urine nucleotide and dTMP. And it may cause atrophy, necrosis and steatosis in liver. These two anticancer drug have well-known hepatotoxicity. So, in this study we compare the gene expression pattern of antitumor agent TAM and MTX, using the cDNA microarray. We have used 4.8 K cDNA microarray to identify hepatotoxicity-related genes in 5-week-old male Sprague-Dawley (SD) rats. Confirm the pattern of gene expression, we have used Real time PCR for targeted gene. In the case of MTX, Protease related gene (Ctse, Ctsk) and Protein kinase (Pctk 1) have shown specific expression pattern. And in the case of TAM, apoptosis related gene (Pdcd 8) and signal transduction related gene (kdr) have significantly up regulated during treatment time. Gene related with growth factor, lipid synthesis, chemokins were significantly changed. From the result of this study, the information about influence of TAM and MTX to hepatoxicity will provide.
Lee, Won Kee,Lee, Shin Yup,Choi, Jin Eun,Seok, Yangki,Lee, Eung Bae,Lee, Hyun Cheol,Kang, Hyo‐,Gyoung,Yoo, Seung Soo,Lee, Myung Hoon,Cho, Sukki,Jheon, Sanghoon,Kim, Young Chul,Oh, In Jae,Na, Koo John WileySons Australia, Ltd 2017 Thoracic cancer Vol.8 No.3
<P><B>Background</B></P><P>This multicenter study was performed to develop a prognosis‐prediction model incorporating genetic polymorphism with pathologic stage for surgically treated non‐small cell lung cancer (NSCLC) patients.</P><P><B>Methods</B></P><P>A replication study including 720 patients and a panel of eight single nucleotide polymorphisms (SNPs), which predicted the prognosis of surgically treated NSCLC in our previous study, was conducted. Using the combined cohort of current and previous studies including 1534 patients, a nomogram for predicting overall survival was made using Cox proportional hazards regression.</P><P><B>Results</B></P><P>Among the eight SNPs, C3 rs2287845, GNB2L1 (alias RACK1), and rs3756585 were significantly associated with overall survival. A nomogram was constructed based on pathologic stage and the genotypes of the two SNPs, and the risk score was calculated for each patient in the combined cohort. Using the prognosis‐prediction model, we categorized patients into low, intermediate, and high‐risk groups, which had greater accuracy in predictive ability (log‐rank statistics = 54.66) than the conventional tumor node metastasis staging (log‐rank statistics = 39.56). Next, we generated a prognosis‐prediction model for stage I to identify a subgroup of potential candidates for adjuvant chemotherapy. Notably, 97 out of 499 stage IB patients were classified as high‐risk patients with a similar prognosis to stage II patients, suggesting the benefit of adjuvant chemotherapy.</P><P><B>Conclusions</B></P><P>This prognosis‐prediction model incorporating genetic polymorphism with pathologic stage may lead to more precise prognostication in surgically resected NSCLC patients. In particular, this model may be useful in selecting a subgroup of stage IB patients who may benefit from adjuvant chemotherapy.</P>
Lee, Jae Yeon,Yoo, Seung Soo,Kang, Hyo-Gyoung,Jin, Guang,Bae, Eun Young,Choi, Yi Young,Choi, Jin Eun,Jeon, Hyo-Sung,Lee, Jaehee,Lee, Shin Yup,Cha, Seung-Ick,Kim, Chang Ho,Park, Jae Yong The Korean Academy of Medical Sciences 2012 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.27 No.12
<P>A genome-wide association study has identified the 15q25 region as being associated with the risk of chronic obstructive pulmonary disease (COPD) in Caucasians. This study intended as a confirmatory assessment of this association in a Korean population. The rs6495309C > T polymorphism in the promoter of nicotinic acetylcholine receptor alpha subunit 3 (<I>CHRNA3</I>) gene was investigated in a case-control study that consisted of 406 patients with COPD and 394 healthy control subjects. The rs6495309 CT or TT genotype was associated with a significantly decreased risk of COPD when compared to the rs6495309 CC genotype (adjusted odds ratio = 0.69, 95% confidence interval = 0.50-0.95, <I>P</I> = 0.023). The effect of the rs6495309C > T on the risk of COPD was more evident in moderate to very severe COPD than in mild COPD under a dominant model for the variant T allele (<I>P</I> = 0.024 for homogeneity). The <I>CHRNA3</I> rs6495309C > T polymorphism on chromosome 15q25 is associated with the risk of COPD in a Korean population.</P>