주폐자충 폐렴으로 발현된 Felty 증후군 1예

김성호,남대근,문재현,김지홍,김보석,안진광,문태건,안병재,김성일 全南大醫大 2001 전남의대학술지 Vol.37 No.3

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

國內飼育 犬에 있어서 心臟絲狀蟲의 感染率에 관한 調査 硏究

Ji Hee Seong(成知禧),Hwa Joong Yoon(尹和重),Won Chang Lee(李元暢),Kwang Ho Kim(金光浩),Seung Won Kang(姜承遠) 한국예방수의학회 1996 예방수의학회지 Vol.20 No.2

The purpose of this study was carried out an epidemiological survey on the prevalence rate of the canine heartworms in Seoul City and the districts of Pa-Ju, Seong-Nam and Po-Chon in Kyonggi province of Korea from September 1994 to the end of September 1995. The blood samples from 292 male and 193 female dogs (pet, 363 ; fighting dogs, 60 ; working dogs, 62) were examined for the adult heartworms cuticle antibodies using the enzyme-linked immunosorbent assay (ELSA) kits. The test was designed to detect the antibodies of the host against the specific cuticle antigens produced with the adult heartworms.

Prediction of Retained Austenite Fraction in Quenching-and-Partitioning (Q&P) Steels Using the Gibbs Energy Balance Approach

Seong Hoon Kim,Ji Hoon Kim,Jae Hoon Lee,Dong‑Woo Suh,Jae Sang Lee 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

Prediction of retained austenite fraction is quite important in designing advanced high strength steels since retained austeniteis the source of transformation-induced plasticity. The present study investigates the phase constitution of a medium-carbonQ&P steel by comparing various approaches to the transformation stasis of bainitic ferrite and applying them to the partitioningprocess. Among them, the modified GEB approach gave the best agreement with the experimental observation, includingthe effects of heat-treatment condition and chemical composition on phase constitution. This indicates phase transformationduring partitioning can be effectively described by the physics of Gibbs energy balance approach.

난소절제후 Estrogen을 투여한 흰쥐 대동맥에서 Protein Kinase C-α와 Fas 발현의 변화

이왕수,이상엽,안지현,송영빈,김학진,이광재,유재격,김상욱,김태호,김치정,류왕성 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3

Estrogen is believed to decrease coronary artery disease. Protein kinase C-α(PKCα)appear to be important in signal conduction pathways. Estrogen treatment increases catalytic activity of PKCα,and activation of PKCαcan modulate estrogen receptor levels and responsiveness. And it was reported that activation of PKC can protect cells from apoptosis induced by Fas ligation. But the beneficial effect of estrogen on PKCαwas not clearly demonstrated. The objective of this study was to evaluate the role of PKCαafter ovariectomy and estrogen therapy in rat aorta. The results were summarized as below: 1. The significant pathological changes were not observed in the rat aorta irrelevant to ovariectomy and estrogen therapy. 2. The expression of Fas was decreased in the aorta of estrogen-treated rats than that of ovariectomized rats without estrogen therapy. 3. Increased expression of PKCαwas more marked in the aprta of estrogen-treated rats than that of ovariectomized rat without estrogen therapy. In conclusion,PKCαmay be important in signal conduation pathway on the effect of estrogen. Activation of PKCαby estrogen reduced Fas expression, suggesting that PKCαactivation may play a role in protection against atherasclerosis. Further studies are needed to elucidate the role of PKCαafter estrogen therapy.

계승치 결손을 동반한 다발성 저위교합 유착 유구치의 관리

박지현,송제선,김성오,손흥규,이제호 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

The infraocclusion usually occurs in the mixed-dentition stage, and it is commonly accepted that the cause of the infraocclusion is ankylosis. The treatment options for patient with infraocclusion of primary molars are observation, restoration or surgical removal of the affected teeth. If the successors are present, most of the infraoccluded and ankylosed primary molars may occur normally. However, when the permanent successors are absent and the progression of infraocclusion is found, affected teeth may need to be extracted. In the case of infraocclusion which can cause vertical alveolar defect due to ankylosis, extraction before growth spurt should be performed for the future prosthetic treatment. A six-year-old female had the ankylosis and infraocclusion of multiple primary molars and congenital missing of premolars. The affected primary molars were extracted before growth spurt to avoid a significant vertical ridge defect and to promote the vertical development of alveolar bone, and the result was observed for many years. The purpose of this report is to report the management of multiple infraoccluded primary molars without permanent successors in a young patient. 저위교합(infraocclusion)은 혼합치열기에 유구치에서 호발하며, 이것은 대부분 이환된 치아의 유착에 의해서 발생하는 것 으로 여겨지고 있다. 유착된 저위교합 유구치의 치료 방법은 크게 치아의 보존 및 관찰, 수복, 발거로 나눌 수 있다. 계승치가 존재하고 경도의 저위교합을 가진 유구치의 경우 자연탈락을 기대할 수 있으나, 계승치가 결손되어 있고 저위교합도 점차 진 행될 경우 이환된 치아의 발거가 필요할 수 있다. 특히 유착으로 인한 수직적인 치조골 소실이 염려될 경우, 추후 보철치료를 위해 환아의 최대성장기 이전에 유착치의 발거를 시행하여야 한다. 본 증례에서는 만 6세의 다발성 유착 유구치 및 저위교합과 계승치 결손을 보이는 환자에서 인접부의 성장에 따른 치조골 의 수직적 결손이 심화되는 것을 막고 정상적인 치조골 성장을 도모하기 위해 최대성장기 이전에 유착치를 발거 후, 장기간에 걸쳐 추적 관찰하였기에 보고하는 바이다.

수종 한약제의 위암세포에 대한 항암작용 효능 검색 및 약리작용에 관한 분자생물학적 연구

김진성,이지향,류봉하,박재훈,지성길,유진화 대한한방종양학회 1999 대한한방종양학회지 Vol.5 No.1

Traditional oriental medicines have ken used for tmament of various kinds of human cancers for long times and some of mem proven to k effective clinical-. However, the pItarmacologica1 actions ad mechanisms related to cancer treatment are generally unknown. In an effort to clarify the action mechanisms of several oriental medicines used for cancer treatments. we planned this experimental praedura. We selected Cadyceps sinensis (동충하초), Punellae Herba (夏柱草), Rehmanniae Radix (熟地黃), Paeoniae Radix (白均案), Oldedamar Herba (白花批告草), Partulaceae Herba (馬首算), Scdopendrasubspinipes mudans (蜈松), Mylabris Phalerara (班藝), Phellinus igniarius(蔡黃), Ganodermae Lignum(靈芝) for evaluation, which have ken used for patients of gastric cancers. The twenty grams of medicines were boiled in 100㎖ of water for 1 hour and filtered with O.2㎛ pore-sized filter unit to remove insoluble particles. Initially we evaluated the effects oriental medicines on growth inhibition in stomach cancer cells. The gastric cancer cell line, AGS, was cultured in RPMI l640 supplemented with lO% heat-inactivated fetal bovine serum and Heated with lO㎕ oriental medicines per l㎖ of medium up to 48 hours. The specimens were subjected to MTT assay for evaluation of growth inhibition. We found mat Mylabris piulema (班 察) markedly supmessed the growth of cancer cells as shown in results. Next, we checked the effects of orielntl medicines on cancer on cell cycles and apMonsis. Mylabrls phalerata (반모) inhibited cell cycle progression of Canea cells a compared with connol cells and cells treated with other medicines. In addition, Mylabri phalerata (반모) induced apptosis in 30-40% of stomch cancer cells within 24 hours. Other oriental medicines used for this experiments did not show apoptosis-inducing effects on cancer cells. Finally, we determined the expmSSion levels of genes associated with cell cycle Md apoptosis. The expressions of bcl-2 and bcl-XL were downregulated by the treamerm of Mylabris phalerata (반모). However, the expression levels of genes related to cell cycles were not altered significantly. In conclusion, we found that Mylams phalerata (반모) has in vivo gowth-inhibiting ad apptosis- inducing effects on stomach cancer cells. However, we think that at least animal experiments are necessay for evduations.

열처리가 Teflon^(??) FEP film의 전하보존특성에미치는 영향

김성준,이현석,김지균,권정열,이헌용 명지대학교 산업기술연구소 2007 産業技術硏究所論文集 Vol.26 No.-

In this paper, we studied the method of electrets electrode which formed to accumulate negative electric charges by corona discharges. The breakdown voltage samples and damaged samples by various corona discharges have made material stabilization and improved characteristics of electric charge storage throughout the annealing processes. After the experiment made material stabilization nearly melting point by many kinds of annealing conditions, we did the corona discharge again by the charged high voltages, a discharge electrode gap, and a discharged time. As we compared it with the best condition, we confirmed that characteristics of electric charge storages were improved.

제7학년 과학의 조석현상 학습을 위한 교재개발과 적용

김은지,임성규 慶北大學校 師範大學 科學敎育硏究所 2007 科學敎育硏究誌 Vol.31 No.-

To help middle school students understand concept of tide, we developed a model of tide, and applied it to students in a middle school in Daegu city to find its effectiveness. The subjects consisted of 136 students of the 7th grade, divided into the experimental group and the control group. The experimental group (N=68) were given a learning cycle model, and the control group (N=68) were given a traditional lecture. The formative evaluation of the experiment was as follows: the average score of the experimental group was 6.43, and that of the control group was 5.68 (its full score 9), The result shows that the teaching method using the tidal model is more effective than the lecture-centered traditional one in helping the students understand the concept of tide. 이 연구는 조석개념에 대한 중학생들의 이해를 돕기 위해 수업에 사용할 조석모형을 개발하였다. 이 조석 모형을 활용한 수업이 중학생들의 조석의 이해에 얼마나 효과적인지 현장에 적용해 보았다. 이 연구의 적용은 대구 시내에 있는 한 중학교의 7학년 136명을 실험집단과 통제집단 의 두 집단으로 나누어 실시하였다 실험 집단(N=68)은 조석 모형을 순환학습 모형의 수업으로 실시하고 통제 집단(N=68)은 전통적 강의식 수업으로 실시하였다. 수업 후에 실시한 형성평가의 결과는,조석모형을 적용한 실험 집단의 평균점수는 6.43점(9점 만점),전통적 강의식으로 수업한 통제집단 은 5.68점으로 실험집단의 평균점수가 더 높았다. 그러므로 조석모형이 7학년 중학생 들의 조석현상의 개념이해에 효과적이었음을 보여준다.

몬도씨병 (Mondor's Disease) 1예

김지은,김유진,서성준,홍창권 중앙대학교 의과대학 의과학연구소 2003 中央醫大誌 Vol.28 No.2-3

Mondor's disease is a rare disorder characterized by superficial thrombophlebitis and usually develop in thoracoabdominal wall. It has clinical feature of sudden development of painful cordlike structure. The cause is not determined in about 50-60% but it is suggested that trauma, surgery, exercise, drug abuse are often associated. A 44-year-old woman presented cordlike linear tender lesion on right thoracoabdominal wall and histopathologic examination revealed thrombophlebitis with organized thrombus.