서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

강우시 채수빈도가 논 오염부하량 산정에 미치는 영향

한국헌,김진호,이종식,이정택,조재영,윤광식 한국환경농학회 2005 한국환경농학회지 Vol.24 No.1

한정된 수질자료를 이용 오염부하 산정시 집중적으로 많은 샘플을 채취한 경우에 비해 어느 정도 차이를 갖는지를 규명하는 것은 모니터링에 따른 오염부하량 산정결과의 신뢰 범위 파악뿐만 아니라 경제적인 수질 샘플 채수빈도 수립에 곡 필요한 것으로 사료된다. 그 결과를 요약하면 다음과 같다. 논에서의 강우-유출시 채수 빈도가 오염부하 산정에 미치는 영향을 파악하기 위해 9개의 강우사상에 대해 2시간 간격으로 연속 수질샘플을 실시하여 분석한 결과 전체적으로 강우-유출과정 중 T-N, T-P, SS 농도는 시간별로 증·감변동을 하였으나 유량과의 상관성은 나타나지 않았다. 수질샘플 횟수에 의한 영향은 강우-유출과정 중 5회 정도 샘플을 실시하면 많은 수의 샘플을 채수한 경우에 비해 T-N ±15.2%, T-P는 -20.0~26.2%, SS는 -28.6~35.7% 범위안에서 오염부하를 추정할 수 있는 것으로 나타났으며, 차이범위가 ±10% 내에 들어가기 위한 샘플수는 일주기 조사시 T-N, T-P의 경우는 6회, SS의 경우는 단기유출시는 4회 정도 실시하면 되고, 장기 유출시에는 11회 정도 실시하면 되는 것으로 조사되었다. 유량-유하부하량 관계식으로 ±10%내의 차이를 보일 샘플횟수는 T-N의 경우는 6회 이상, T-P와 SS는 9회 이상 정도 실시하면 되는 것으로 조사되었다. In order to examine effects of sampling frequency during rainfall-runoff process from paddy field on the estimation of pollution load, EMCs of several water sampling frequencies were examined. Water quality samples were conducted by every two hours interval for each event. It was found that difference of load estimation between five times sampling and two hours consecutive sampling during rainfall-runoff showed 15.2~-15.2% for T-N, 20.0~-26.2% for T-P, 28.6~-35.7% for the SS, respectively. In the same way, the effects of number of sampling data on estimation of pollution load using runoff-mass load(L-Q) method were investigated. L-Q equation made of five times sampling data provided 10% differences in estimation of mass loads of T-N, T-P, and SS when compared to those by L-Q equation using entire two hours consecutive sampling data during runoff process.

Acriflavine-Guanosine 복합제 (AG60)의 조직내 분포에 대한 형광현미경적 연구

고정식,임수재,안의태,김진국,김상건,이경영,강종구,홍은경,정영신,유보림,한영복 대한해부학회 1999 Anatomy & Cell Biology Vol.32 No.1

저분자량 폴리에틸렌이민을 이용한 유전자 송달 및 발현 유효성 연구

정길재,박귀례,신지영,최한곤,오유경 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.4

Branched and linear polyethylenimines (PEIs) have been studied as efficient and versatile agents for gene delivery in vitro and in vivo. PEIs exist in a linear or branched topology and are available in a wide range of molecular weight (Mw). Most studies have been done using PEIs with Mw higher than 10Kd. This study was aimed to test the transfection efficiency and the cell viability following gene delivery using PEI of Mw 2Kd, a relatively lower Mw cationic polymer. We used murine interleukin-2(mIL-2) plasmid DNA complexed with branched PEI 2Kd or 25Kd, and transfected them into a myoblast muscle cell line, C2C12. The cellular uptake of mIL-2 plasmid DNA was determined using quantitative polymerase chain reaction. RNA transcript levels were studied in the myoblast cells. Our results show that PEI 2Kd was as effective as PEI 25Kd in celluar gene delivery and transfection efficiency in C2C12 cells. Moreover, MTT assay indicated that PEI 2Kd/DNA complexes did not significantly reduce the cell viability regardless of N/P ratios. These results suggest that PEI of Mw 2Kd might play a role as effective and low toxic nonviral vector systems for muscular cell lines.

有機製品의 物性改質에 必要한 Silicone 架橋劑開發에 관한 硏究

韓貞璉,梁在乾,鄭一鉉,裵長淳 단국대학교 1985 論文集 Vol.19 No.-

Alkoxysilanes were synthesized by me alcoholysis of trichbromethyhilanc having trifunctional group with corresponding alcohols under sodium alkoxide or HCl acceptor. The yields of the products were more than 80%. It was found that the rate of the hydrolysis of ethoxysilane was faster than methoxysilane. Hexamethyldisilazanes were synthesized by the reaction of chlorotrimethylsilane with ammonia gas or ammonium liquid solution. The yields of the products were 86% and 26% respectively. As the results of hydrolysis of disilazanes prepared under acidic, neutral, and alkali solutions, the rate of the hydrolysis was increased with the order of alkali, neutral, and acidic solution. After synthesizing α,ω-dichloromethylsiloxane by the reaction of diethoxydimethylsilane with dimethyldichlorosilane, α,ω-dichloromethylsiloxanol with terminal hydroxyl group was prepared by the hydrolysis of the product. p-Phenylene-bis-dimethylchlorosilane was prepared through Grignard reaction of p-dibromobenzene with dimethyldichlorosilane, and then p-phenylene-bis-dimethyltydroxysilane was synthesized by the hydrolysis of p-phenylene-bis-dimethylchlorosilane. α,ω-dichloromethylsiloxane

Horseshoe Appliance를 이용한 Ⅲ급 부정교합의 교정적 접근

한지혜,김재곤,,백병주,양연미,서정아 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

성장기 아동의 Ⅲ급 부정교합의 치료에는 많은 악기능 정형장치가 사용되어 왔으며 다양한 형태로 변화하여 발전되어 왔다. Horseshoe appliance는 Schwarz에 의해 소개된 장치로서 elastic의 견인력으로 장치의 free sliding 효과를 통해, 하악와와 과두의 관계를 재정립시켜, 악골 주위의 연조직이나 muscle matrix와 조화되는 새로운 위치에 하악골을 repositioning시켜 악골관계를 개선시킬 수 있다. 또한 하악의 후하방 회전 효과를 극소화시켜 전안면고경의 증가를 방지할 수 있고, 구외 장치에 비해 환자의 협조도가 좋다. 저자들은 전치부 반대교합을 주소로 전북대학교 치과병원 소아치과에 내원한 Ⅲ급 부정교합 환자에게 Horseshoe appliance를 사용한 결과 하악골에 대한 상대적인 상악골의 전방 성장과 교합평면의 반시계방향 회전, 상악 전치의 순측 경사와 하악 전치의 설측 경사로. 3개월 내에 전치부 반대교합이 해소되는 효과를 얻었다. The Horseshoe appliance was introduced by Dr. Schwarz, and it is used to correct sagittal relationships by elastic force in class Ⅲmalocclusion.It minimizes the increment of lower anterior facial height and allows the mandible to be repositioned harmoniously with the soft tissue and muscle matrix of the jaw. It has the advantages of better patient cooperation, easier construction, and more effective modification. In the patients who were treated with Horseshoe appliance, forward growth of maxilla and counterclockwise rotation of occlusal plane with labioversion of maxillary incisors and linguoversion of mandibular incisors were obtained Minimum downward and backward rotation of mandible was accepted, so increasing of lower anterior facial height was minimized.

비강 및 비인두에 발생한 도립유두종과 편평상피암종의 p53단백 및 세포증식능에 관한 연구

한주호,윤기중,이재규,신대균,박근호,조향정,문형배 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

The inverted papilloma and squamous cell carcinoma are common neoplasia in the sinonasal cavity and nasopharynx, but the incidence of these tumors are very low and the study on the oncogenesis or biological activity of the tumor cells are not well known. This study was designed to evaluate the oncogenic roles of the p53 gene and the proliferative activity of the tumor cells in the inflammatory polyp, inverted papilloma and squamous cell carcinoma. The experiment was carried by the immunohistochemical stains about the p53 protein, PCNA and Ki-67, histochemical stain about the AgNORs. and flow cytometric analysis about the DNA ploidy using the formalin fixed paraffin embedded tissues. The frequency of the expression of p53 protein was 0%(0/16 cases) in the inflammatory polyps, 18.8% (3/16 cases) in the inverted papillomas, and 87.5%(14/16 cases) in the squamous cell carcinomas. The labelling index(%) of the PCNA and Ki-67 was 5.3% and 3.3% in the inflammatoy polyps, 29.6% and 25.2% in the inverted papillomas, and 51.9% and 36.8% in the squamous cell carcinoma. The expression of the PCNA and Ki-67 was distributed in the periphery of the tumor islands of the inverted papilloma and was distributed in the both of center and periphery of the tumor islands of the squamous cell carcinoma. The number of nuclear AgNORs was increased in the order of inflammatory polyps (0.96), inverted papillomas(1.34) and squamous cell carcinoma(2.09). The frequency of the DNA aneuploidy was 0%(0/16 cases) in the inflammatory polyps, 18.8%(3/16 cases) in the inverted papillomas. and 12.5%(2/16 cases) in the squamous cell carcinomas. Above results indicates that the changes of the p53 gene and proliferative activity of the tumor cells are involved on the oncogenesis and the biological activity of the inverted papilloma or squamous cell carcinoma in the nasopharynx and sinonasa cavity.

R.M. Rilke의〈Die aufzeichnungen des malte laurids brigge〉에 나타난 사랑의 意味

韓在弘,鄭仁模 부산대학교 과학교육연구소 1986 교사교육연구 Vol.13 No.-

Hier wird 》das Mysterium der Liebe《 in Rilkes "Die Aufzeichnungen des Malte Laurids Brigge" untersucht, das als Raum der Erkenntnis der menschlichen Existenz bezeichnet werden kann. Malte erfa··hrtsein Leben in Paris von Furcht und Angst erfu··llt. Er fa··lltzuerst in Verzweiflung und findet keinen Ausweg. Aber allma··hnlichversucht er diese Angst vor dem Tod und seinem Leben durch die Liebe zuu··berwinden. Malte sieht die Liebe nicht so, wie sie allgemein verstanden wird, sondern als die Erkenntnis der menschlichen Existenz. In dieser Arbeit habe ich zuerst das Angstmotiv und das Todesmotiv erforscht, die Malte immer in sich tra··gt. Dann habe ich das Liebesmotiv nach drei Gesichtpunkten untersucht: Liebe ohne Erwiderung, Liebe aus der Hingegebenheit des Elends und Liebe zu Gott. Schließlich wird 》das Mysterium der Liebe《 als der Weg der Erkenntnis der eigenen u·· berzeitlichen Existenz aufgezeigt.

주부의 토종닭에 대한 인식 및 이용실태에 관한 조사

한재숙,한경필,김정숙,김미향 동아시아식생활학회 1996 동아시아식생활학회지 Vol.6 No.3

This survey was carried out as part of a basic works to improve the extention of native chicken uses. A sample of 282 housewives living in the downtown area of Taegu city were examined using an original questionnaire about their awareness and uses of a native chicken. The results were as follows : The awareness for a chicken dish is significantly different according to the housewives' ages and many respondents evaluated the nutritive value of a native chicken. The housewives preferred chicken boiled plain, spice fried chicken and stewed chicken, in the order. But family members preferred chicken boiled plain, spice fried chicken and french fried chicken, in the order. The frequencies of chicken cooking and buying chicken dishes of the housewives were once per month and they regarded a native chicken as one of traditional, health and natural foods. They appreciate the taste of a native chicken highly and recognized the price of a native chicken expensive. Also 52.5% of housewives could distinguish a native chicken from the others.