부산·울산·경남지역 직업병 감시체계

김정일,김병권,김정원,채창호,이철호,강동묵,김지홍,김진하,김영욱,이영하,이지호,김정호,윤형렬,유철인,정백근,장태원,김운규,윤동영,강진욱,김종은,안진홍,이동준,장준호,이광영,송혜란,최영희,이용환,조병만,최홍렬,고상백,김은아,이유진,홍영습,정갑열,김정만,김준연 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

Objective: Occupational medicine specialists in the Busan, Ulsan and Kyung-Nam areas established an area-based occupational disease surveillance system and used this system to collected case information for the purpose of preventing occupational diseases Methods: l l hospital participated in this system. The authors selected five main diseases, which were hand-arm vibration syndrome (HAVS), work-related musculoskeletal disorder (WRMSD), occupational asthma, occupational skin disease and occupational and occupational lung cancer and established their case definitions. All cases were reported on the web, and real time analysis was conducted. Results: Between April 2001 and April 2003, 192 cases of HAVS, 118 cases of WRMSD, 33 cases of occupational asthma, 17 cases of occupational skin disease and 17 cases of occupational lung cancer (for a total of 377 cases of these five main diseases) were reported. most of the HAVS cases came from shipbuilding, and 172 of them (92.7%) were associated with grinding. Of the four main types of WRMSD, carpal tunnel syndrome (CTS) was the most prevalent with 46 cases and shipbuilding was also the main industry involved (83.9%). The ergonomic risk factors involved mainly associated with the hand. In 19 (57.6%) and 4 (12.1%) cases of occupational asthma, the agents involved. The causative agents of occupational lung cancer included Cr, welding fume, PAH, Ni, etc. 10(58.8%) of the cases were diagnosed as squamous cell carcinoma and 5(29.4%) as adenoma. Conclusion: This result showed that an area-based occupational disease surveillance system might provide an effective method of evaluating the prevalence of such diseases, however the Busan, Ulsan and Kyung-Nam provinces are too large to be treated as individual areas. Therefore, the authors suggest that each province should establish its own surveillance system.

전문비서직에 대한 이대 비서학과 학부학생들의 의식구

구효선,김경화,윤혜정,이지연,정은희,강은정,김윤희,신해정 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

복막투석복막염 환자에서 발생한 창자벽공기증 1예

정선영,나지훈,최윤정,고성애,조규향,박종원,도준영,윤경우 영남대학교 의과대학 2009 Yeungnam University Journal of Medicine Vol.26 No.1

Peritonitis is a serious problem in patients undergoing peritoneal dialysis. Rarely pneumatosis intestinalis can occur as a complication of this infectious process. Pneumatosis intestinalis is a potential life threatening condition with a challenging management. The mortality of peritoneal dialysis patients with pneumatosis intestinalis secondary to mesenteric ischemia is almost 100%. We describe a rare case of pneumatosis intestinalis in a peritoneal dialysis patient who developed Staphylococcus aureus peritonitis which was initially treated with appropriate antibiotics. Since initial response to therapy was not achieved, an abdominal computerized tomography was done which revealed a pneumatosis intestinalis. A laparotomy was performed and small bowel necrosis was seen. A segmented resection with ileostomy, jejunostomy was done. Though surgical treatment was performed, the patient died in 2 weeks after admission. Pneumocystitis intestinalis in peritoneal dialysis peritonitis is a uncommon complication which requires prompt evaluation to rule out mesenteric ischemia as it carries a high mortality and its management will be surgical.

경상북도 영덕 방언의 특징

윤지희,김해정 동국대학교 국어교육과 2000 동국어문학 Vol.12 No.-

대장암 세포주 SNU C2A에서 etoposide처리에 의한 apoptosis 유도

정지연,나윤숙,정호철,오상진 Official Journal of the Korean society for immunol 2001 Immune Network Vol.1 No.3

레티노인산이 배양 각질형성세포의 사이토카인 생성에 미치는 영향

김지윤,정승용,오성민,김수찬 大韓皮膚硏究學會 2003 大韓皮膚硏究學會誌 Vol.10 No.4

교잡종 찰옥수수에 대한 연구 III : Ⅲ. 국내 옥수수 유전자원 수집종에 대한 주요 특성 분포

서정은,주현민,최윤표,홍범용,조양희,주정일,지희정,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

2006년 국내 각 지역으로부터 수집된 재래종옥수수 유전자원을 관행방법에 의해 파종하고 주요특성별로 분포도를 살펴본 결과는 다음과 같다. 1. 수집된 유전자원에 대한 발아율은 대부분 80∼100%이상의 분포를 보였으나, 일부 수집계통에는 30% 미만의 극히 저조한 발아율을 보였다. 2. 수집자원에 대한 초기생육을 살펴보면 극히 생육이 저조한 것이 40% 정도를 보였고, 극히 우수한 자원은 3%미만으로 나타났다. 3. 간장은 대부분이 150∼199cm범위에 55%가 분포하고 있었으나, l00cm이하가 5%, 250cm이상이 8%로 나타나 수집종간에 큰 차이를 보였다. 4. 주당 분얼수는 1개 미만이 40%의 분포를 보였으나, 일부 수집종에서 2 내지 3개의 분얼수를 보이는 계통이 확인되었다. 5. 개화소요일수는 61∼64일의 범위에서 40%, 57∼60일의 범위에서 30%의 분포를 보였으며, 특히 일부 수집종의 경우 55일 이하의 극조생종도 10% 정도의 분포를 보였다. 6. 이삭길이는 대부분 11∼15cm범위에 60%가 포함되어 있으나, 일부계통에서 5cm미만이 2%, 16∼20cm의 이삭길이도 10%가 분포하였다. Germination ratio on the 300 collected genetic resources showed 80 to 100 percentage, but those of some accessions were very low as below 30 percentage. Early growth phase of most of these lines were very poor while some collected lines were very vigor. Range of stem height showed from 150 to 199cm, but that of some accessions showed below 100cm as five percentage and some of them was over 250cm as eight percentage. Number of tillers per plant appeared less one but some collected lines have two to three tillers per plant. In days to tasseling, some accessions showed more four per plant. Ear length of these accession showed above 60 percentage as 11 to 15cm, while that of some collected lines showed over 10 percentage as 16 to 20cm.

석류 과피 추출물의 라디칼 소거활성

최윤정,오영지,정동선 서울여자대학교 2010 자연과학연구논문집 Vol.22 No.-

Antioxidant activity and total phenolic contents of Punica granatum peels were investigated. The pomegranate peels were extracted with 70% methanol (ME) and then partitioned to hexane (HF), ethyl acetate (EAF) and water (WF) fractions. Total phenolic contents and radical scavenging activities of each extract and fraction from Punica granatum peels were measured. The ethyl acetate fraction showed the highest radical scavenging activity, followed by methanol extract, water fraction and hexane fraction. The IC50 values of EAF were 0.144 ㎍./mL and 0.50 ㎍./mL for DPPH and ABTS radicals scavenging activities, respectively. A strong antioxidant activity of the EAF from pomegranate peels was correlated with its high level of total phenolic contents (740.0 mg of tannic acid equivalent/g). ME and WF also exhibited relatively strong radical scavenging activities with IC50 values of 6.70 ㎍./mL and 7.25 ㎍./mL for DPPH radical, and 17.4 ㎍./mL and 18.33 ㎍./mL for ABTS radical, respectively. These results suggest that the pomegranate peels possess strong antioxidant activity, and can be a useful source of natural antioxidant.

분화중인 흰쥐 콩팥의 요세관에서 nNOS의 발현

송지현,류시윤,김진,정주영 韓國電子顯微鏡學會 2008 Applied microscopy Vol.38 No.2

Nitric oxide는 콩팥에서 혈류의 조절, 사구체 혈액역동학 및 요세관의 운반에 중요한 역할을 하는 인자로서 최근 세포의 주기조절, 유사분열에도 관여하는 것으로 알려져 있다. 최근 연구결과에 의하면 발생중인 콩팥에서의 nNOS의 발현은 성체와는 다른 것으로 알려져 있으나, 발생중인 콩팥에서의 발현 양상 및 발현시기 등에 대해서 알려진 바 없다. 따라서 본 연구에서는 발생중인 콩팥을 이용하여 분화중인 요세관에서 nNOS의 발현양상을 관찰하고자 하였다. 성체에서 nNOS의 면역반응성은 사구체 보우만주머니의 벽측상피와 치밀반, 내림가는부분 및 수질집합관에 발현되었다. 발생중인 콩팥에서는 임신 15일에 처음 발현하기 시작하였으며, 그 부위는 원위세관의 굵은오름부분이었다. 임신 20일에서 출산후 14일까지 새로이 형성되는 요세관의 굵은오름부분에서 관찰되었으나, 분화를 마친 요세관에서는 그 발현 양상이 감소하였다. 출생후 21일경에는 최종적으로 치밀반에만 국한되어 발현되었다. 속수질에서는 내림가는 부분과 속수질 집합관에서 발현되었으며 그 양상은 수질 중간부위에서 강하게 발현되었으며 시작부위와 말단부위에서는 약하게 발현되었다. 이상의 결과로 보아 굵은오름부분에서의 nNOS의 발현은 요세관의 분화정도와 일치하며 특히 그 발현양상이 분화가 활발한 시기에 강하게 발현되고 분화가 저하된 후에는 발현이 감소하는 것으로 보아 발생중인 콩팥의 성장에 중요한 역할을 할 것으로 생각된다. Nitric oxide (NO) is an important regulator of renal blood flow, glomerular hemodynamics, and tubule transport processes in the kidney. There is also evidence that NO is involved in cell cycle regulation and mitotic division. During development the nNOS expression pattern differs from that observed in adult animals. However, little is known about temporal and spatial patterns of nNOS expression in the developing kidney. The purpose of this study was to establish the time of expression and the distribution of nNOS in the developing rat kidney. Kidneys from 14-, 16-, 17-, 18-, and 20-day-old fetuses, 1-, 4-, 7-, 14-, and 21-day-old pups, and adult animals were preserved and processed for immunohistochemistry. In the adult kidney, nNOS was detected in the parietal epithelium of Bowman’s capsule, macula densa, descending thin limb and inner medullary collecting duct. nNOS immunoreactivity appeared first in the distal tubule anlage at 15 days of gestation, and in all epithelial cells of developing thick ascending limbs (TAL) as well as macula densa of 17- and 18-day-old fetuses. From 20 days of gestation to 14 days after birth, nNOS was expressed in the newly formed cortical TAL, which are located in the medullary ray, whereas in mature TAL of juxtamedullary nephrons, nNOS immunolabeling gradually decreased in intensity and became restricted to the macula densa. In inner medullary collecting ducts, nNOS immunoreactivity appeared first at 7 days after birth in the papillary tip and gradually ascended to the border between outer and inner medulla. In the descending thin limb and parietal epithelium of Bowman’s capsule, weak nNOS immunoreactivity was observed at 14 days after birth and labeling gradually increased to adult levels at 21 days after birth. These results suggest that differential expression of nNOS in the developing kidney is an important physiological regulator of renal function during kidney maturation.

발치 및 비발치 치료 전후 악궁 폭경의 변화

전지윤,김수정,강승구,박영국 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.1

일반적으로 네 개의 소구치 발치를 동반한 교정치료는 비발치 치료에 비하여 치열궁 폭경을 더 좁게 만들어, 미소 시 구각 부위에 어두운 구강 내 공간, 소위 buccal corridor를 형성함으로써 비심미적인 결과를 낳는다는 견해가 있다. 한편 발치 치료는 오히려 하악의 견치간 폭경을 증가시키며, 비발치 치료와 비교하여 악궁 폭경의 변화에 있어 유의한 차이를 보이지 않는다는 상반된 연구결과가 존재한다. 이 연구는 발치 치료와 비발치 치료 시 악궁 폭경의 변화를 관찰하여 실제적으로 발치 치료가 미소 시 협측 분절에 미치는 영향을 규명하고자 시행되었다. 경희대학교 치과병원 교정과에서 치료받은 환자 중 전악에 고정식 장치를 사용하여 네 개의 제1소구치 발치 치료를 받은 30명과 비발치로 치료한 30명의 치료 전후 연구 모형을 비교 분석한 결과 악궁 폭경의 변화는 다음과 같다. 네 개의 제1소구치 발치 치료 시 비발치 치료와 비교하여 상악의 견치간 폭경 변화는 유의한 차이가 없었으나, 하악의 견치간 폭경은 유의하게 더 많이 증가하였다. 구치간 폭경 변화는 상악과 하악 치열궁 모두에서 두 군 간에 유의한 차이가 나타났는데, 발치군에서 구치간 폭경이 감소한 반면에 비발치군에서는 구치간 폭경이 증가하였다. 미소 시 노출되는 악궁 폭경은 비발치군보다 발치군에서 더 크게 나타났으며, 이는 치열궁 폭경의 축소가 발치 치료 시 당연히 예상되는 결과가 아님을 시사한다. Objective: This study was performed to investigate the influences of extraction and nonextraction treatment on smile esthetics by measuring dental arch width changes. Methods: Pretreatment and posttreatment study models of 30 first premolar extraction cases and 30 nonextraction cases were randomly selected to determine whether extraction treatment results in narrow dental arches, and a consequent unaesthetic smile. Arch widths were measured from the cusp tips of the canines and the first molars. Posterior arch widths were also measured at a constant arch depth derived by averaging randomly chosen nonextraction models. Results: The intercanine widths increased significantly in the extraction sample, whereas the intermolar widths decreased significantly. The arch width at a standardized arch depth was significantly wider in the extraction subjects. Conclusion: These results elucidate that constriction in arch width is not a materialized consequence of extraction treatment. It leads to postulate that an esthetically compromising effect from narrow dental arches on smile is hardly anticipated with extraction treatment.