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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
저혈청 배지에서 인간 전골수세포(HL-60)를 이용한 tPA 생산과 세포사멸기작에 관한 연구
김현구,성기돈,김태호,안주희,함문선,박진서,이현용 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1
tPA 생산과 세포 사멸의 연구를 하기 위해서 인간 전골수세포가 배양되었다. 연속 관류 배양하에서 최대 tPA 생산량은 324 ng/ml이며 최대 세포 농도는 5.27×10 exp (6) cells/ml였다. Phorbol ester를 넣었을 때 tPA 생산량은 420 ng/ml까지 향상되었다. 형광 현미경으로 관찰했을 때, apoptosis는 세포 배양 초기부터 중반까지 우세했고 빠른 교반 속도에서도 우세했다. 그러나 necrosis는 세포배양 말기와 동결된 세포가 해동 되었을 때 우세했다. HL-60 was cultivated to produce tPA (tissue-type plasminogen activator) and study the mechanism of cell death. Maximum cell density and tPA production were obtained as 5.27×10 exp (6) cells/ml and 324 ng/ml, respectively under perfusion cultivation. tPA production was enhanced to 420 ng/ml in adding 160 nM of phorbol ester. The cells were gradually differentiated to granulocytes rather than proliferation. By Fluorescent microscope, apoptosis was prevailed except the death phase and in high agitation speed, but necrosis was prevailed in thawed cells and during the latter periods of the cultivation. It was also proved that tPA was most produced in apoptosis. To obtain higher tPA productivity, the cells must be maintained in apoptosis, not necrosis phase when the cells were dying.
김관태,고현송 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2
Ten patients, who had once lumbar disc surgery, underwent reoperation at the same level because of recurred disc herniation. Most symptoms and signs are the recurrence of pain, sensory and motor deficit, limitation of straight leg raising. All patients proved to have no psychological or compensation problems. The favorable results were presented in patients with snapping or lifting injury. No significant association was found, at any stage of the anlysis, between the outcome and symptom-free-interval after the first operation. The clinical results were affected predominently by the extracted disc amount and cause of injury. Microsurgery is advisable in reoperation because it can fasciltate the dissection between fibrous scar and nerve root.
모래의 입도분포가 모르터의 물성에 미치는 영향에 관한 연구
김경원,김문희,김유진,안흥난,허태경,현철 경성대학교 공학기술연구소 2010 공학기술연구지 Vol.16 No.-
Fineness Modulus is a term used as an index to the fineness of sand. It is well - known that the modulus distribution of sand plays an important role in achieving the desired properties of mortar. The maximum size of sand is also important parameter in mortar. These parameters affect workability, strength and unitweight of mortar. In tills study, different sand gradings were used to investigate effects of fineness moduli of sand for examination about the workability, strength and unit weight characteristics of cement mortar. Two kinds of sands with various size distribution and three kinds of fine aggregates with the similar particle size distribution (Sieve No.16~30, No.30~50, No.50~100) were used. Water-cement ratio (W/C) of mortar mix was kept constant for all the trial mixes with sand of different fineness modulus. Major findings of tills study are: (a) Fine sand with the similar size distribution reduces the workability and unit weight of cement mortar. (b) The compressive strength of mortar is not sensitive to sand grading variations. (c) The compressive strengths at the age of 28 days range from 32.1 to 54.1 MPa. (d) The sand with standard modulus distribution has better positive effects on the properties of the mortar.
김현태,이상무,어수택,박춘식,정성환,허승재,남충희,강창희,김용훈 순천향대학교 1994 논문집 Vol.17 No.4
We analysed 404 patients with primary lung carcinoma who were treated at Soonchunhyang University Hospital from July, 1985 to september, 1993 in order to investigate the survival rate and epidemiolgical properties of primary lung cancer. They were 330 males and 74 females. The most prevalent decade was seventh. In terms of cell type, the squamous cell was 225 patients (55%), and adenocarcinoma, small cell, mixed type was 21%, 19%, 4%, respectively. Among non-small cell lung carcinoma, stage Ⅲa was the most prevalent one(92%). In case of small cell carcinoma, the limited stage was 64%. The 12-, 24-, 36- month survival rate of total patients was 57%, 31%, 22%, respectivley and median sruvival time was 15 months. The 36-month survival rate tended to be longer in non-small cell lung carcinoma than that of small cell lung cancer, but there was no difference between two groups, statistically. In non-small cell carcinoma, The 36-month survival rate and meidan survival time were longer in the stage Ⅰ and Ⅱ than those of Ⅲa, Ⅲb, Ⅳ (80% versus 38%, 22%, 0%, p<0.05). According to involvement of lymph node, the 36-month survival rate was longer in NO and N1 than those of N2, N3 (61.9%, 48.7% versus 17.7%, 17.3%, p<0.05). In small cell carcinoma, The 36-month survival rate and median survival rate were higher and longer in limited stage than those of extensive stage(16.1% and 13 month vs 10% and 8 month, p<0.05). In conclusion, we report here the incidence of primary lung carcinoma and the survival rate of paients with primary lung carcinoma who were treated in Soonchunhyang University Hospital.
김기동,전인우,김태현 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.B
The shipbuilding scheduling has many possible alternatives because of its long time horizon and a lot of jobs, so it is required that the scheduling system can generate and search feasible alternatives rapidly. The scheduling in the assembly shop is initiated by allocating, namely loading, the assembly blocks to each shop. In this step, the resource capacities (such as available man/hour, available crane) of each shop must be considered. The result of loading without above consideration can make the scheduling result based on that infeasible or worse one. In this paper, we developed the optimal scheduling system of shipbuilding, specifically for loading and scheduling of assembly block, using ILOG Solver/Scheduler. ILOG Solver/Scheduler is a general-purposed commercial software which supports to find a feasible or optimal solution using object oriented technique and constraints satisfaction programming, given constraints and objectives. Also, in order to enhance the system performance, we conducted various experiments of ILOG search strategies. The experimental results showed that the impact of search strategies is significant.