Repellent efficacy of essential oils and plant extracts against Tribolium castaneum and Plodia interpunctella

Lee Hwa‐Eun,Hong Su Jung,Hasan Najmul,Baek Eun Joo,Kim Jun Tae,Kim Young‐Duk,Park Mi‐Kyung 한국곤충학회 2020 Entomological Research Vol.50 No.9

This study was conducted to investigate the repellent efficacy of essential oils (Origanum vulgare, Pimpinella anisum, and Tanacetum cinerariifolium) and four plant extracts (Agastache rugosa, Capsicum annuum, Citrus reticulata, and Ginkgo biloba) against Tribolium castaneum (adults and larvae) and Plodia interpunctella (larvae). Gas chromatography/mass spectrometry analysis revealed the presence of carvacrol, anethole, and jasmolin I as the predominant constituent in O. vulgare, P. anisum, and T. cinerariifolium, respectively. Furthermore, ethyl hexopyranoside, 9,12‐octadecadienoic acid, cyclopentanol, and 2‐cresol were identified in A. rugosa, C. annuum, C. reticulata, and G. biloba, respectively. The repellent efficacy of each essential oil, plant extract, and the combination of oils was evaluated using a specially designed cylinder trap for 120 h. Among the three oils, O. vulgare and T. cinerariifolium had greatest repellent efficacy against P. interpunctella larvae. T. cinerariifolium exhibited effective repellence against the adults and larvae of T. castaneum. Therefore, O. vulgare (O) and T. cinerariifolium (T) were selected for further investigation of combined effects. Two essential oils were mixed in three different ratios of OT1 (1:3), OT2 (1:1), and OT3 (3:1). The repellent efficacies of OT1 and OT2 against the adults of T. castaneum were significantly greater than that of OT3. OT1 was effective against the larvae of T. castaneum, whereas OT2 was effective against the larvae of P. interpunctella. OT1 enhanced the repellent efficacy by approximately five times against larvae of T. castaneum, compared with that of T. cinerariifolium. Overall, OT1 was selected as the best repellent substance against all the tested insects.

위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

농작물 해충 및 진균류 방제를 위한 방선균의 분리 및 동정

이은정,강경돈,황교열,김두호,김신덕,성수일 한국잠사학회 1998 한국잠사곤충학회지 Vol.40 No.1

Twenty seven out of ca. 5,000 actinomycete strains, which were isolated from soil collected throughout the country, showed antimicrobial effects against fungi, Rhizopus stronifer (ATCC6227a), Rhizoctonia solani (KCCM 11271) and yeast, Candida albicans(ATCC10231). From these antifungal microorganisms, we further selected seven strains which seemed to produce insecticidal substances with in vivo test, using silkworm, Bombyx mori and beet armyworm, Spodoptera exigua. Morphological and biochemical experiments revealed that three strains out of seven were streptomyces. Further investigations on the physical and chemical properties of these antifungal and insecticidal substances are now in progress.

간호 학생의 임상실습 효율을 위한 기초 조사 연구

이애경,김정애,주미경,정안순,배경진,김정수,이정애,장은정 경복대학 2000 京福論叢 Vol.4 No.-

임상실습 교육은 간호이론을 실무에 적용하는 기회를 제공하는 과정으로서 임상실습이 간호교육의 중요한비중을 차지하고 있다는 것은 주지의 사실이다. 이러한 중요성에도 불구하고, 임상실습 교육에 즉각적인 해결이 어려운 많은 문제점이 있음도 이미 알고 있는 사실이다 이에 임상실습 교육의 기초 자료로 활용되고 있는 실습목록표에 대한 간호 학생들의 실습목표의 명확한 이해와 더불어 이론과 실습의 연계성을 강화시키고자 하였다. 성인간호, 모성간호, 이동간호 3개 영역 모두에서 공통적으로 기본임상간호 항목이나 기본간호술과 관련된 항목에서 직접수행의 빈도가 높았고 숙련된 기술적인 처치나 전문성을 필요로 하는 항목에서는 관찰과 수행경험이 부족한 것으로 나타났다. Clinical performance is not only the process of providing the opportunity for applying nursing theory into practice but also it is a well-known fact that clinical performance is an important part in nursing education. lnspite of this importance, it is also true that many problem with no immediate solution exist in clinical performance of nursing students. thus, through measuring and analyzing the degree of clinical experience of the nursing students, on the nursing checklist that is being used as the basic guide in clinical education, we tried to clearly understand the objectives of clinical performance and to emphasize the connection between theory and clinical performance. The results of the study showed that the frequency of directly performing tasks was high in all areas of adult health nursing, maternity nursing, and child nursing for the items of basics clinical nursing and items related with basic nursing techniques, and that the experiences of observation and execution were lacking in the items needing skilled treatment or speciality.

건식과 습식 반탄화 바이오매스의 화학적 구조적 특성

이은주,정수아,정예진,형세진,이재원 전남대학교 농업과학기술연구소 2022 농업생명과학연구동향 Vol.60 No.-

The study analyzed the physical and chemical properties of dry-torrefied (DT) and wet-torrefied (WT) biomass. Hemicellulose was mainly degraded by torrefaction, and the contents of glucan and lignin were relatively increased. The degradation rate of biomass was higher in WT (18.25%–23.13%) than in DT biomass (3.12%–3.83%), and it increased with increasing reaction time. Torrefaction improved the crystallinity of the biomass from 36.88% in the raw material to a maximum value of 60.97% in the biomass subjected to wet torrefaction for 30 min (WT-30). The thermal stability of torrefied biomass was improved in WT-10 (17.21%), WT-60 (15.38%), and DT-60 (8.74%) compared to that of the raw material (2.35%). The hydrophobicity and fine particle distribution of biomass were increa- sed by torrefaction, with the lowest water absorption (3.08%) and the highest distribution of fine particles (8.20%) being observed in WT-60 biomass.

태아의 하악에서 발견된 이상결절 1례의 연구

이치연,이동주,조이수,김승인,이지연,김은철 원광대학교 생체재료·매식연구소 1996 원광생체재료·매식 Vol.5 No.2

Dens evaginatus is a rare developmental anomaly in which an enamel-covered tubercle projects from the occlusal surface of a tooth. usually lower second premolar. When the tubercle fractures, the pulpal extension into the tubercle may be exposed, which results in early pulpal necrosis, periapical infection and even osteomyelitis. We found the dens evaginatus in 16-week-old fetal mandible. Microscopically, we observed the protrusion of dental papilla into the dental organ and hard tissue formation which will be the tubercle by serial section. This anomaly was reported to be very rare in tooth development of fetus, so we reported this finding with brief review of literatures.

악교정 수술 후 발생하는 신경회복에 대한 연구Ⅰ

이동근,조이수,민승기,오승환,정창주,이은택 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2

Dysfunction of the inferior alveolar nerve indicated by various degree of numbness of the lower lip and chin is one of the few drawbacks of mandibular osteotomy, especially Bilateral Sagittal Split Ramus Osteotomy(BSSRO) and genioplasty. Although it has been recorded throughout the history of this techniques, it is true etiology poorly understood. In this study, 22 consecutive patients under class III malocclusiion impression and undergoing orthognathic surgery(BSSRO only 11 case, BSSRO with genioplasty 11 case) were studied using 4 neurosensory test(static light touch, directional discrimination, two-point discrimination, pin pressure nociception) with post OP 1 week, 2 weeks,4 weeks, 8 weeks, 12 weeks, 24 weeks, On control group, 10 members without trauma and nerve damage history, nerve test was accomplished. We concluded majority of patients return of sensation during post operative 24 weeks. Althought immediate nerve deficit are 92.2%, 97.2% 88.9% these are recovered to 25%, 35.72%, 10.71% at 24 weeks. Nerve recovery rate increased prominently between post 4 weeks and 8 weeks. There is no statistically difference about neurosensory deficit among the chin area. Neurosensory deficit more severe when the BSSRO with genioplasty group than the only BSSRO group. Immediate neurosensory deficit is larger left side than right side but after 6 months, there is no significantly difference between left side and right side. Static light touch and pin pressure nociception are more sensitive method of neurosensory deficit than two point discrimination.

독성 물질 측정을 위한 Photobacterium phosphoreum의 고정화에 관한 연구

이은수,이홍주,전억한 경희대학교 생명자원과학연구원 1998 硏究論文集 Vol.19 No.-

독성 물질 측정용 P phosphoreum의 고정화 물질 선택을위하여 고정화 방법을 크게 4가지로 나누어서 그 방법에 따라 각각 고정화 물질 한가지씩을 선택하여 P phosphoreum의 bioluminescence 안정성을 알아보았다. Polyacrylamide나 collagen에서는 bioluminescence가 유지를 못하고 20분 안에 급격히 떨어졌으나, alginate와 k-carrageenan은 온도를 높여야 gel이 형성되는 성질을 갖고 있기 때문에 저온성 발광 미생물인 P phosphoreum에 적합한 matrix가 되지 못한다. 따라서 P phosphoreum의 biluminescence를 안정되게 유지하면서 고정화가 용이한 polymer로는 alginate가 적합한 고정화 물질로 선정되었고 독성물질에 대한 P phosphoreum의 민감성을 bioluminescence의 변화로 살펴본 결과 각각의 독성 물질마다 특이한 linearity한 관계식이 설정되었고 EC_(50)를 쉽게 구할 수 있었다. The bacterial bioluminescence has been studied to detect toxic materials m foods and environment. A monitonng system can be developed with a fact that the bioluminescence is mhibited sensitively when the bioluminescent bacteria are exposed to toxic substances. However, a stability of bioluminescence must be improved for the purpose of developing continuous monitoring system. The mmobilization of Photobacterium phosphoreum, therefore, was investigated m view of long term of bioluminescence stability. Various matrixes, sodium algmate, k-carrageenan, collagen and polyacrylamide were studied for proper immobilization matnx of P. phosphoreum, in order to improve stability of bioluminescence. Collagen and polyacrylamide were shown to be madequate matenals for immobilization of P. phosphoreum since the bioluminescence decreased when cells were mixed with such matnx due to toxic effect of free radicals of matnx. In case of k-carrageenan, the biolumexence was stable compared with collagen and polyacrylamide. However, the k-carrageenan was not also a suitable matnx because cells were not able to mix with the matnx properly m low temperature at which gel is formed and, especially, cells of P. phosphoreum are psychrophilic luminescent bacteria. With a sodium algmate, the bioluminescence was stably maintained for 20 minutes and, in addition to that, a process of immobilization was simple for bioluminescent bacteria. Therefore, by using a sodium algmate as an mobduahon matrix, the relationship between biolummescence of immobilized P. phosphoreum and each toxic substance was shown linearity and could calculate EC_(50).

복합식 히트펌프 설계를 위한 액체건조제 제습기의 성능 특성에 관한 실험적 연구

이수동,정진은,박문수 한국기술교육대학교 2004 論文集 Vol.10 No.2

A liquid desiccant for hybrid heat pump system undergoes various influences by several working factor. This paper presents the study of six options in related with the dehumidification rate and efficiency absorption in the dehumidification system. The effect of operating variables such as inlet solution concentration, inlet solution flow rate, inlet solution temperature, inlet air flow rate, inlet air temperature, and brine temperature was analyzed. The experimental dehumidifier has been designed to study the dehumidi- fication characteristics of the aqueous triethylene glycol(TEG) system. The performance characteristics of the absorption dehumidification system can be used effectively to save energy by reducing latent heat load. The result of this experiment can provide useful data for hybrid air conditioning system.