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      • KCI등재

        김경욱 소설의 서사 패턴과 리듬

        김원희 ( Kim Won-hee ) 한국문학이론과 비평학회 2008 한국문학이론과 비평 Vol.40 No.-

        The objective of this article is to analyze the distinctive features of narration embodied in Kyeong-Wook Kim's novels focusing on aspects of narrative pattern and rhythm. Characteristics of Kim's narrative pattern and rhythm revealed as a results of the analysis is as follows; First, the narrative pattern of separate angle showed in Kim's novels, such as 「Was an actor GY Jang dead(장국영이 죽었다고)?」, 「Go to meet Betty(베티를 만나러 가다)」, 「Private life of a cat(고양이의 사생활)」, 「Dangerous reading(위험한 독서)」, repeatedly brought out the mutual text into discontinuous rhythm relief. Second, the narrative pattern of image deconstruction appeared in Kim's other novels, such as 「An alibi for butterfly(나비를 위한 알리바이)」, 「My love, Nakasaki(나가사키 내 사랑)」, 「The recent state of you(당신의 근황)」, 「99%」, restored mutual text to an image of chaos and exposed continuous rhythm by concatenating the image of narrative reality. The shift from the narrative pattern of separate angle to image deconstruction reflects the change of Kim's view of the world from transient anonymity to real-name identity. Kim inquired deeply into the root of modern human being living with digital media and culture of post-modern society by playing a variation on the narrative pattern and rhythm in his novels. That is why his novels are crucial for estimating new narrative trends of 21st century Korean novels.

      • KCI등재후보

        김유정 단편소설의 크로노토프와 식민지 외상의 은유

        김원희(Kim, Won-Hee) 부경대학교 인문사회과학연구소 2011 인문사회과학연구 Vol.12 No.2

        이 글은 김유정의 단편소설「산ㅅ골나그내」와「만무방」의 크로노토프를 파악하는 방식으로 작가의 현실인식을 구명하였다. 김유정의 단편소설에서 식민지 외상의 징후를 내포하는 크로노토프는 식민지 현실의 시간성과 공간성의 다층적 연관으로 작중 인물의 궁핍한 삶과 애환을 입체적으로 보여준 작가의 세계관과 소통할 수 있는 통로이다. 이러한 접근 방법으로 팔지는 「산ㅅ골나그내」, 「만무방」등의 텍스트에 내재된 식민지 크로노토프를 통하여 다음과 같이 작가의 탈식민주의 의식과 소통하였다. 먼저, 「산ㅅ골나그내」텍스트의 식민지 크로노토프를 통하여서는 쇠돌이와 거지아낙의 결혼과 배반으로 구체화된 산골 나그네의 식민지 외상으로서 민초들의 삶의 애환과 절망을 산간 농촌, 주막, 의복, 물방앗간, 길 등의 은유로 보여주는 작가의 연대의식과 소통하였다. 거지 아낙이 쇠돌이를 배반하고 그의 옷을 훔쳐 도망 갈 수밖에 없는 사정은 식민지 궁핍한 민초들의 절망적인 삶의 은유라면, 거지 아낙과 그의 남편이 머무른 물방앗간에 대한 과거와 현재의 시공간적 대비는 식민지 주권을 상실한 민족 정체성의 은유로 읽혀진다. 산골 나그네의 정체성과 ‘물방울이 벽에 부딪치는 소리’와 ‘늑대의 성난 소리’ 등의 자연 묘사로 식민지 외상의 징후를 내포하는 은유는 식민지 민초들의 분노와 절규에 대한 독자의 연대의식을 증폭시키는 효과를 갖는다. 다음으로, 「만무방」 텍스트의 식민지 크로노토프를 통하여서는 무능한 응칠과 성실한 응오의 상반된 삶의 태도가 결국 주권 잃은 민초들의 삶의 당위성으로 만무방의 의미가 극적 반전되는 식민지 역사의 구조적 모순을 만무방, 산골 농촌, 집, 추수, 때, 천, 길 등의 은유로 보여주는 작가의 비판의식과 소통하였다. 30년 전과 현재를 바라보는 응칠이의 시점에는 식민지 이전과 이후 현실의 대비로 식민지지 역사들 비판하는 작가의 세계관이 반영되어 있다. 만무방으로 포착된 식민지 외상으로서 은유는 식민지 현실의 구조적 모순이 한 개인의 삶의 가치와 태도에 따라 개선될 수 있는 것이 아니라, 국권을 잃은 민초들의 비극적 삶의 당위성임을 강조하는 식민지 역사 비판의식으로 이해된다. 만무방의 정체성과 ‘철(때)이 나지 않은 딱한’ 현실로 식민지 외상의 징후를 내포하는 은유는 식민지 역사에 대한 독자의 비판의식을 확대하는 효과를 거둔다. 이와 같이 김유정의 단편소설에 내재된 크로노토프는 식민지 외상의 징후를 보여주는 작가의 세계관적 은유로 독자의 연대의식 내지는 비판의식을 끌어낸다. 결과적으로 필자는 김유정 소설의 식민지 크로노토프를 통하여 식민지 민초들의 피폐한 삶과 애환을 입체적으로 보여준 작가의 역사의식이 리얼리즘 문학이 추구하는 비판적 현실인식과 닮아 있을 뿐만 아니라, 궁극적으로는 작가의 세계관이 탈식민주의 의식과 닿아 있음을 밝힐 수 있었다. The object of this article is to discuss the chronotope and prospect reflected on Yujcong Kim’s short stories, such as “A Mountain Vagabond”, “Man-Mu-Bang”. This analysis is crucial because it make deep meaning of Kim’s short stories enable to interpret on the side of writer’s intention by analysing the metaphor of colonial trauma. The name of Kim’s short stories, such as “A Mountain Vagabond”, “Man-Mu-Bang”, itself construct a metaphor system. The interpretation of the chronotope and prospect reflected on Kim’s short stories is as follows. First, “A Mountain Vagabond” shows the chronotope of colonial symptoms through the metaphor of ‘sparrow’ and ‘mill house’ while expecting ‘solitude’ and ‘oddness’. Poverty of peoples betrayed because of ‘clothes’ are enforced by ‘sound of water fronting wall’ and ‘sound of wolves’ and is felt with compassion and solidarity by readers. Second, “Man-Mu-Bang” install a metaphor of the hope of overcoming colonial trauma by comparing before and after the colonial periods. This reflects colonial trauma by awakening criticism that the life of peoples losing their sovereignty is contradicted one. The figuring of chronotope and prospect constructing a metaphor in Kim’s short stories awaken overall criticism of readers by prospecting colonial trauma and diagnosis, not merely describing the folkway of his home country. This work will prove that Kim’s short stories is highly contributed to the enlargement of the realism of Korean modem history of literature.

      • KCI등재

        정신분열병에 대한 리스페리돈의 효과 및 안정성

        이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

        연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

      • KCI등재후보

        조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

        김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

        Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

      • DATA BASE SYSTEM DEVELOPMENT AND STATISTICAL ANALYSIS OF EIR3 ACCIDENTS OF SEVERAL COUNTRIES

        Kim,In-Tae,Kim,In-Won,Song,Hee-Oeul 한국화재소방학회 1997 한국화재소방학회 학술대회 논문집 Vol.1997 No.-

        The fire accident cases of several countries such as Korea, Japan, United States, etc., were collected and compared statistically. The trends of fire accidents in several countries will help us establish detailed plans for fire protection and reduce the possible fire accidents in the future. For construction of data base system, the program FADS was developed, which is operable in Windows environment.

      • SCOPUSSCIEKCI등재

        측뇌실내 종괴의 감별진단 및 수술적 치료

        김동규,김봉수,이상형,심기범,왕규창,정희원,김현집,조병규,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.2

        We present a series of 42 patients with the lateral ventricular mass lesions who underwent operative removal between 1979 and 1992 at the Seoul National University Hospital. These lesions included 29 tumors, 10 benign cysts and 3 arteriovenous malformations. There were 20 lesions in the trigone, 14 in the frontal horn, 6 in the body, and 2 in the temporal horn. Together with the age of the patient, the location in the lateral ventricle and the CT or MR patterns, the range of the differential diagnosis of the lesions can be narrowed. The mass were removed by various surgical approaches ; 11 by the middle frontal gyrus, 10 by the superior parieto-occipital, 13 by the middle temporal gyrus, 4 by the anterior transcallosal, 2 by the posterior transcallosal and 3 by the combined approaches. The superior parieto-occipital approach left postoperative morbidities in 64% and other approaches in 20 to 25% of the cases. These morbidities included hemiparesis, hemianopsia, aphasia, memory distubance and seizure. Most hydrocephalus disappeared without the shunting procedure after removal of the lateral ventricular mass. The high frequency of postoperative complications in the superior parieto-occpital approach require meticulous consideration in the selection of this approach.

      • KCI등재

        피질하 혈관성 치매와 호모시스테인 및 MTHFR C677T 유전자 다형성의 상관관계

        김희진,김지영,김숙희,김원기,김용성,최병옥 대한치매학회 2004 Dementia and Neurocognitive Disorders Vol.3 No.2

        Background: Subcortical ischemic vascular dementia (SIVD) frequently causes dementia in elderly people, and elevated plasma homocysteine concentrations have been reported to be associated with vascular dementia. Although the homozygous C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene can induce hyperhomocysteinemia, the association between MTHFR C677T polymorphism and SIVD has not been studied. Therefore, we examined the association of SIVD with plasma homocysteine concentration and MTHFR C677T polymorphism. Methods: We enrolled 58 patients with vascular dementia (VaD), 43 patients with SIVD, 69 lacunar infarct patients without vascualr dementia (LOD), and 232 healthy individuals and checked their fasting plasma homocysteine levels and analyzed the C677T polymorphism in the MTHFR gene. Results: The mean plasma homocysteine level in VaD, SIVD, and LOD patients were significantly higher than that in healthy controls (p;0.01). The odds ratio adjusted with age, sex, hypertension, diabetes mellitus, and smoling were significantly higher in VaD (OR, 2.74; 95% CI, 1.04 to 7.23) and SIVD (OR, 3.12; 95% CI, 1.09 to 8.96) than that in controls. Compared with LOD, it was significantly higher in SIVD, but not in VaD (OR, 4.50; 95% CI, 1.05 to 19.26). In SIVD patients, the OR of plasma homocysteine level was higher in the TT genotype than those in the CC genotype (OR, 1.59; 95% CI, 1.01 to 2.49). Conclusions: Our findings suggest that elevated plasma homocysteine concentration and the MTHFR 6777 genotype are associated with SIVD.

      • 정신훈련 프로그램의 실시에 따른 체육수업 참여유형 비교연구

        김원배,김정수,정청희,노희덕,홍준희 師範大學 體育硏究所 1998 서울大學校 體育硏究所論集 Vol.19 No.1

        The purpose of this study was to identify the student participation styles in elementary school physical education classes. To identify the student participation styles, the factors such as subject, teacher, parents, the level of family economy and classroom environments were investigated. To achieve the purpose of this study was observed during 3 months in 1997. Educational ethnography was used in order to collect qualitative date. The subjects were 40 students on grade 4 in Chang Soe elementary school. Student participation styles were categorized six domains based on classroom teacher's observation and evaluation about them for 4 months. This styles included 'enthusiastic students', 'officious helpers', 'modifiers', 'ball girl-ball boys', 'timid paragons', and 'halfway students' Enthusiastic student was characterised by learning ability and attitude in his classroom, Officious helper by interference in other students in classes, Modifiers by the his tendency of exchange and execuse about the teacher-assigned-task, Ball girls-ball boys by yield their opportunity to participation in games and took peripherial position as by-hnaders, Timid paragons by work his task only when the teacher let him ordered and listen to teacher's explanation attentively, Halfway students by very bad learning attitude and made distribute the learning circumstances by their mischief. The result of this study were as follows;

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