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김상훈,황락경,진준장,고일규,김용복,윤혜선,백성수 대한배뇨장애요실금학회 2021 International Neurourology Journal Vol.25 No.S2
Purpose: Exercise is a representative noninvasive treatment that can be applied to various diseases. We studied the effect of resistance exercise on motor function and spatial learning ability in Parkinson disease (PD) mice. Methods: The rotarod test and beam walking test were conducted to evaluate the effect of resistance exercise on motor function, and the Morris water maze test was conducted to examine the effect of resistance exercise on spatial learning ability. The effect of resistance exercise on brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) expression and 5’-adenosine monophosphate-activated protein kinase (AMPK) phosphorylation was investigated by Western blot analysis. New cell generation was confirmed by immunohistochemistry for 5-bromo-2’-deoxyuridine. Results: Resistance exercise improved coordination, balance, and spatial learning ability in PD mice. Resistance exercise enhanced new cell production, BDNF and TrkB expression, and AMPK phosphorylation in PD mice. The effect of such resistance exercise was similar to that of levodopa application. Conclusions: In PD-induced mice, resistance exercise enhanced AMPK phosphorylation to increase BDNF expression and new neuron generation, thereby improving spatial learning ability. Resistance exercise is believed to help improve symptoms of PD.
고용 강화 및 결정립 미세화를 통한 마그네슘 합금 주조재의 기계적 물성 향상
김상훈,문병기,유봉선,박성혁 한국주조공학회 2017 한국주조공학회지 Vol.37 No.6
This study investigated the effects of the addition of Zn, Ca, and SiC on the microstructure and mechanical properties of Mg-Al alloys. The tensile properties of homogenized Mg-xAl (x = 6, 7, 8, and 9 wt.%) alloys increased with increasing Zn content by the solid-solution strengthening effect. However, when the added Zn content exceeded the solubility limit, the strength and ductility of the alloys decreased greatly owing to premature fracture caused by undissolved coarse particles or local melting. Among the MgxAl- yZn alloys tested in this study, the AZ74 alloy showed the best tensile properties. However, from the viewpoints of the thermal stability, castability, and tensile properties, the AZ92 alloy was deemed to be the most suitable cast alloy. Moreover, the addition of a small amount (0.17 wt.%) of SiC reduced the average grain size of the AZ91 alloy significantly, from 430 μm to 73 μm. As a result, both the strength and the elongation of the AZ91 alloy increased considerably by the grain-boundary hardening effect and the suppression of twinning behavior, respectively. On the other hand, the addition of Ca (0.5-1.5 wt.%) and a combined addition of Ca (0.5-1.5 wt.%) and SiC (0.17 wt.%) increased the average grain size of the AZ91 alloy, which resulted in a decrease in its tensile properties. The SiC-added AZ92 alloy exhibited excellent tensile properties (YS 125 MPa, UTS 282 MPa, and EL 12.3%), which were much higher than those of commercial AZ91 alloy (YS 93 MPa, UTS 192 MPa, and EL 7.0%). The fluidity of the SiC-added AZ92 alloy was slightly lower than that of the AZ91 alloy because of the expansion of the solid-liquid coexistence region in the former. However, the SiC-added AZ92 alloy showed better hot-tearing resistance than the AZ91 alloy owing to its refined grain structure.
김상훈,김태은,최종수,Kim, Sang-Hoon,Choi, Jong-Soo,Kim, Tae-Eun 한국정보처리학회 2003 정보처리학회논문지B Vol.10 No.5
본 논문에서는 2장의 영상으로부터 카메라 내부 파라미터를 추출하는 교정 방법을 제시한다. 카메라 교정은 2차원 영상으로부터 3차원 정보를 얻기 위해서는 필수 불가결한 기술이다. 기존의 많은 연구들이 수행되어 왔는데, 영상내에 체크 패턴을 포함한 3장의 영상을 이용하는 방법과 연속된 3장의 영상으로부터 Kruppa 방정식을 풀어 카메라 교정하는 방법이 대표적인 예가 되겠다. 본 논문에서는 인간이 만든 조형물에서 쉽게 발견할 수 있는 기하학적인 정보를 이용하여 보다 쉽고 빠르게 내부 파라미터를 추출한다. 이러한 내부 파라미터는 소실점들로부터 추정되며 대응되는 2장의 영상에서 대응점들로부터 외부 파라미터를 추출할 수 있다. 이렇게 교정된 내부, 외부 파라미터를 이용하여 사영 행렬을 유도하고, 유도된 사영행렬로 3차원 정보를 얻게 되고 3차원 재구성을 구현하게 된다. This paper proposes a calibration method from two images. Camera calibration is necessarily required to obtain 3D Information from 2D images. Previous works to accomplish the camera calibration needed the calibration object or required more than three images to calculate the Kruppa equation, however, we use the geometric constraints of parallelism and orthogonality can be easily presented in man-made scenes. The task of it is to obtain intrinsic and extrinsic camera parameters. The intrinsic parameters are evaluated from vanishing points and then the extrinsic parameters which are consisted of rotation matrix and translation vector of the camera are estimated from corresponding points of two views. From the calibrated parameters, we can recover the projection matrices for each view point. These projection matrices are used to recover 3D information of the scene and can be used to visualize new viewpoints.
건설공사의 적정 Lot Size 결정에 의한 효율적인 재고관리 방안에 관한 연구
김상훈,김광희,강경인 한국건축시공학회 2004 한국건축시공학회지 Vol.4 No.2
The purpose of this study was to look up the proper inventory management system in construction industry. it is important for construction company to improve competitiveness and to reduce construction cost. Lot-sizing techniques were applied to rebar procurement in apartment project. The results of this study were as follows; the method of Groff's marginal cost showed the best performance of other techniques and the method of Norman showed a similar result.