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      • SCOPUSKCI등재

        Which Environmental Factors Caused Lammas Shoot Growth of Korean Red Pine?

        Lee, Chang-Seok,Song, Hye-Gyung,Kim, Hye-Soo,Lee, Bit-Na-Ra,Pi, Jeong-Hoon,Cho, Yong-Chan,Seol, Eun-Sil,Oh, Woo-Seok,Park, Sung-Ae,Lee, Seon-Mi The Ecological Society of Korea 2007 Journal of Ecology and Environment Vol.30 No.1

        Lammas growth, a rare phenomenon for Korean red pine (Pinus densiflora), occurred in 2006. Lammas shoots showed higher frequency and longer length in Seoul's hotter urban center than in urban boundary or suburban forest sites. Frequency and length showed a close correlation with urbanization density and vegetation cover expressed in NDVI. Air temperature in the late summer of 2006 was more than $1^{\circ}C$ higher than an average year. Of the predominant environmental signals that modulate bud flush, only temperature changed significantly during the year. Differences in temperature between the urban centers, urban boundaries and suburban forests correlated with varying land-use density. The rise in temperature likely spurred lammas growth of the Korean red pine. Symptoms of climate change are being detected throughout the world, and its consequences will be clearer in the future. Considerate interest in the responses of ecological systems to the variable changes is required to prepare for unforeseeable crises. Monitoring of diverse ecological phenomena at Long Term Ecological Research sites could offer harbingers of change.

      • KCI등재

        Image Contrast Enhancement by Illumination Change Detection

        Bayanmunkh Odgerel(바잉뭉흐 어드게렐),Chang Hoon Lee(이창훈) 한국지능시스템학회 2014 한국지능시스템학회논문지 Vol.24 No.2

        영상처리를 통한 이동 물체 인식과 화질 개선 등의 연구에서 조명 변화가 성능에 큰 영향을 미치기 때문에 조명 변환에 대한 대응은 컴퓨터 비전 응용 분야에서의 중요한 관심사 중 하나이다. 조명 변화를 감지할 수 있게 되면 변화가 있는 시점에서부터 적절한 개선 알고리즘을 적용함으로써 인식률 향상 및 화질 개선 효과를 증대시킬 수 있다. 이에 본 연구에서는 급격한 조명 변화를 감지함에 있어 실시간성을 얻기 위하여 지역 정보를 이요하고 퍼지 논리를 도입하여 이를 효과적으로 감지하는 방법을 제안한다. 급격한 조명 변화를 감지하는 효과적인 방법으로 모서리 영역과 가운데 영역에 대한 각각의 히스토그램의 평균과 편차, 그리고 변화 추이를 반영하기 위하여 이전 프레임의 각 영역에 대한 히스토그램의 평균과 편차와의 변화량을 입력으로 급격한 조명 변화가 있을 때 입력 값의 변화 패턴을 퍼지 규칙으로 만들어 조명 변화를 감지 하도록 하였다. 또한 움직이는 물체에 가려 발생하는 변화와 구별하기 위하여 전체 영역에 대한 평균과 편차 변화량을 도입하여 논리적으로 추론하여 차이를 구별할 수 있도록 하였고 점진적으로 조명이 변화하는 것을 감지할 수 있도록 하였다. 다양한 테스트 데이터에 대해 객관적인 정확도 측정 기법을 이용하여 민감도와 특이도를 계산하여 제안한 방법의 효용성을 보였다. 적응형 뉴로-퍼지 추론시스템을 도입하여 대비제한 적응 히스토그램 평활화 (CLAHE)의 매개 변수를 자동으로 선택할 수 있는 방법을 제안하여 급격한 조명의 변화를 감지한 결과를 바탕으로 화질을 개선할 수 있음을 보였다. There are many image processing based algorithms and applications that fail when illumination change occurs. Therefore, the illumination change has to be detected then the illumination change occurred images need to be enhanced in order to keep the appropriate algorithm processing in a reality. In this paper, a new method for detecting illumination changes efficiently in a real time by using local region information and fuzzy logic is introduced. The effective way for detecting illumination changes in lighting area and the edge of the area was selected to analyze the mean and variance of the histogram of each area and to reflect the changing trends on previous frame’s mean and variance for each area of the histogram. The ways are used as an input. The changes of mean and variance make different patterns when illumination change occurs. Fuzzy rules were defined based on the patterns of the input for detecting illumination changes. Proposed method was tested with different dataset through the evaluation metrics; in particular, the specificity, recall and precision showed high rates. An automatic parameter selection method was proposed for contrast limited adaptive histogram equalization method by using entropy of image through adaptive neural fuzzy inference system. The results showed that the contrast of images could be enhanced. The proposed algorithm is robust to detect global illumination change ,and it is also computationally efficient in real applications.

      • Long second toe: its nail and skin changes

        ( Geun-hwi Park ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

        Background: Nail can be affected by trauma, infection, and systematic disorders. In particular, the toe nails are exposed to the repeated and cumulative minor traumas, which usually result in thickened, splitted, and discolorated nails. Considering these, it can be inferred that the long second toe can be related to various nail and skin changes by repeated minor traumas such as friction in shoes, but the study or report on this topic hasn’t been done yet. Objectives: The purpose of this study was to introduce various nail and skin changes on long second toe. Methods: We analyzed the kinds of nail/skin changes of 50 patients with long second toe, enrolled at Pusan National University Hospitals (Busan and Yangsan) from 2013 to 2018. Results: There was no significant difference in the incidence of left and right toe and toenail, and 7 (14%) patients presented bilateral distribution. The most common nail change on long second toe was melanonychia (23, 46%), followed by subungual hematoma (15, 30%), onycholysis (2, 4%), subungual hyperkeratosis (2, 4%), onychomadesis (1, 2%), and retronychia (1, 2%). The most common skin change was corn (9, 18%), followed by paronychia (2, 4%). Twenty (20/50, 40%) patients also had other toe or toenail changes. Among them, the most common site was big toe/nail (13, 62%), and the most common change was subungual hematoma (8, 42%). Conclusion: Through this study, the dermatologists can recognize and diagnose the nail and skin changes of long second toe.

      • Optically isotropic switchable microlens arrays based on liquid crystal

        Lee, You-Jin,Yu, Chang-Jae,Lee, Jae-Ho,Baek, Ji-Ho,Kim, Youngsik,Kim, Jae-Hoon The Optical Society 2014 Applied optics Vol.53 No.17

        <P>We present an optically isotropic switchable microlens array (MLA) based on liquid crystals (LCs) using the Joule heating electrode structure. The LC molecules were initially aligned vertically on the lens and electrode surfaces. By applying voltage to the transparent electrodes, the temperature of the LC layer could be changed. Above the clearing point temperature of LCs, the LC layer shows an averaged refractive index that differs from the nematic state refractive index. The MLA could have switching characteristics by index matching between the LC layer and polymer lens structure. The proposed switchable MLA shows high light efficiency with truly optically isotropic properties.</P>

      • KCI등재
      • 흰쥐에서 알코홀의 전투여가 halothane 마취시 간에 미치는 영향

        이상동,공명훈,장성호 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.3

        Fifty nine male Sprague-Dawley rats were used to investigate the hepatic effects of halothane anesthesia in alcohol-treated rats. Sampling was done before intravenous injection of ethyl alcohol(400mg/kg) or saline(5m1/kg) through tail vein. And 24 hours laterall rats were exposed to halothane-N_(2)/O_(2) (1%-2ℓ/2ℓ) for two hours. Intracardiac puncture for blood sampling was done after intraperitioneal injection of pentobarbital (50mg/kg) and hepatectomy was done to get the tissue sample for microscopic examination 24hours or 96 hours after halothane anesthesia. Biochemical studies including liver and renal function variables (protein, albumin, total bilirubln, direct bilirubin, aspartate aminotransferase, alanine aminotransferse, alkaline phosphatase, BUN, creatinine) were done and the hepatic tissue was examined with light microscopy. The results are summarized as follows: 1) Twenty four hours after halothane anesthesia. protein albumin. total bilirubin. and alkaline phosphatase were significantly changed in both saline- and alcohol-treated rats. Serum transaminases level were not significantly changed in alcohol-treated group compared with saline-treated group (i.e. aspartate aminotransferase. alanine aminotransferase). Other parameters indicative of hepatic and renal function such as cholesterol. BUN and creatinine were not significantly changed. 2) There is no significant difference of histologic evidence of hepatic damage between alcohol- and saline-treated rats 24 hours after halothane anesthesia. 3) Ninety six hours after halothane anesthesia. protein. albumin and total bilirubin were significantly changed in both saline- and alcohol-treated rats. Serum transaminases and alkaline phosphatase level were not significantly changed in alcohol-treated group compared with saline-treated group (i.e., aspartate aminotransferase. alanine aminotransferase). Other parameters indicative of hepatic and renal function such as cholesterol. BUN, and creatinine were not significantly changed. 4) There is no significant difference of histologic evidence of hepatic damage between alcohol-and saline-treated rats 96 hours after halothand anesthesia.

      • KCI등재후보

        2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

        이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

        목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

      • Effects of aerosol on evaporation, freezing and precipitation in a multiple cloud system

        Lee, Seoung Soo,Kim, Byung-Gon,Yum, Seong Soo,Seo, Kyong-Hwan,Jung, Chang-Hoon,Um, Jun Shik,Li, Zhanqing,Hong, JinKyu,Chang, Ki-Ho,Jeong, Jin-Yim Springer-Verlag 2017 Climate dynamics Vol.48 No.3

        <P>Aerosol effects on clouds and precipitation account for a large portion of uncertainties in the prediction of the future course of global hydrologic circulations and climate. As a process of a better understanding of interactions between aerosol, clouds and precipitation, simulations are performed for a mixed-phase convective multiple-cloud system over the tropics. Studies on single-cloud systems have shown that aerosol-induced increases in freezing, associated increases in parcel buoyancy and thus the intensity of clouds (or updrafts) are a main mechanism which controls aerosol-cloud-precipitation interactions in convective clouds. However, in the multiple-cloud system that plays much more important roles in global hydrologic circulations and thus climate than single-cloud systems, aerosol effects on condensation play the most important role in aerosol-induced changes in the intensity of clouds and the effects on freezing play a negligible role in those changes. Aerosol-induced enhancement in evaporation intensifies gust fronts and increases the number of subsequently developing clouds, which leads to the substantial increases in condensation and associated intensity of convection. Although aerosol-induced enhancement in freezing takes part in the increases in condensation by inducing stronger convergence around cloud bottom, the increases in condensation are similar to one order of magnitude larger than those in freezing. It is found that while aerosol-induced increases in freezing create intermittent extremely heavy precipitation, aerosol-induced increases in evaporation enhance light and medium precipitation in the multiple-cloud system here. This increase in light and medium precipitation makes it possible that cumulative precipitation increases with increasing aerosol concentration, although the increase is small. It is interesting that the altitude of the maximum of the time- and domain-averaged hydrometeor mass densities is quite robust to increases in aerosol concentration. This is because locations of gust fronts and homogeneous freezing do not vary significantly with changing aerosol concentration and this outweighs aerosol effects on hydrometeor size.</P>

      • Pulmonary Inflammatory Pseudotumor with Solitary Plasmacytoma of Bone Mimicking Advanced Lung Cancer

        ( Chang Hoon Kim ),( Jae Seok Jeong ),( Yong Chul Lee ),( So Ri Kim ),( Yeong Hun Choe ),( Seung Yong Park ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-

        Lung cancer has been the most commonly diagnosed type of cancer and the leading cause of cancer related mortality in Korea and worldwide. Although it is fatal, most of the lung cancer patient are asymptomatic at the time of diagnosis. Therefore, radiologic screening by chest low-dose computerized tomography (LDCT) has been recommended by lung cancer specialists for early detection and improving survival. However, clinical suspicion of lung cancer by radiologic screening is quite challenging because of its high false positive rate. A wide range of benign pulmonary diseases could be misinterpreted as lung malignancy on LDCT, including infection, benign mass-forming lesion, and inflammatory changes. Therefore, physician should consider the possibility of the benign disease entities when radiologic features suggest lung malignancy. Herein, we report a case of a 50-year-old man presenting a 4.5-cm lung mass in the right upper lobe with solitary osteolytic lesion of the right 8th rib. Under the suspicion of metastatic lung cancer, the lung mass and the right 8th rib were surgically resected for the diagnostic and curative purpose. After the tissue biopsy, unexpectedly, the lung mass was diagnosed as inflammatory pseudotumor. Furthermore, histopathology of the resected rib showed solitary plasmacytoma of the bone. Our experience highlights the importance of clinical suspicion that in patients with radiologic features compatible to advanced lung cancer could be caused by coexistence of unrelated two uncommon disease entities, which can be completely treatable with surgical resection.

      • 소아ㆍ청소년기에 발병한 탈모증의 정신의학적 특성

        이길홍,이헌재,이창훈 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.2

        연구목적: 소아 청소년기에 조기 발병한 탈모증과 성인기에 발병한 탈모증 환자들의 개인적 특성이나 탈모 양상, 정신의학적특성, 동반신체질환 및 치료 방법에 관한 비교 분석을 통해 조기 발병탈모증의 치료 및 예방지침을 수립하기 위해 본 연구를 시도하였다. 방법: 1998년 1월부터 1999년 6월까지 중앙대학교 용산병언 피부과에 내원하여 정신과로 의뢰된 탈모증 환자 93명(남 40명, 여 53명) 중에서 소아 청소년기에 발병한 31명(남 14명, 여 17명)을 연구대상 집단으로 선정하였고, 성인기에 발병한 탈모증 환자 62명(남 26명, 여 36명)을 대조군으로 선정하여 양군간의 임상 양상의 차이를 비교 분석하였다. 수집된 자료는 SPSSWIN 9.0V 프로그램을 통해 자료 처리를 하였고, 집단간의 차이는 교차 분석 및 t-검정을 통해 비교 분석 하였다. 결과: 1) 조기에 발병할수록 가을에 출생하고, 환자나 부모의 사회 경제 수준의 높으며, 형제수가 적다. 2) 조기에 발병할수록 전신성 탈모가 많고, 탈모 과거력이 있으며, 3회이상 재발하고, 탈모 정도가 심하며, 탈모기간이 2년 이상 장기간이고, 첫 탈모부위가 두정부이며, 탈모부위가 두군데 이상이고, 치료를 해도 변화가 없거나 악화되고, 치료를 자의 중단하거나 효과가 없어 중단한 경우가 많다. 3) 조기에 발병할수록 가정내 적응이나 인간관계에서 적응상의 어려움을 겪으며, 입시 부담이나 학교생활에서의 변화로 인해 학교 스트레스를 경험한 비율이 높다. 4) 조기에 발병할수록 불안장애가 많고, 불안증상과 우울증상을 많이 호소하며, 인격장애가 있을 때 탈모가 촉진되고, 특히 히스테리성인격이나 의존성인격을 지닐수록 조기에 탈모가 발생한다. 5) 조기에 발병할수록 지루성피부염등 동반 피부질환이 많고, 정신과약물인 alprazolam을 복용하고 있으며, polytar나 tretinoin을 처방한 비율이 높다. 결론: 일차 진료의사인 피부과 의사들은 공존하는 정신장애에 대해 깊은 관심을 갖고, 청소년기 이전부터 조기에 탈모증의 공동 치료 계획을 세워야 한다. Objectives: There have been growing interests about alopecia occured during childhood and adolescence in clinical practice. The purpose of this paper is to explore the clinical characteristics of early onset alopecia in order to establish effective psychiatric intervention strategy. Method: The subjects were 31 early onset alopecia patients(14 males, 17 females) and 62 late onset control patients(26 males, 36 females). These patients had visited psychiatric outpatient clinic consulted from the department of dermatology, Yongsan hopital, Chung Ang University, Seoul, Korea, from January 1998 to june 1999. The sociodemographic data, clinical pattern of alopecia, psychiatic characteristics, comorbid physical illnesses and treatment variables were assesed. The data was statistically analyzed using chi-squre test and t-test through SPSSWIN 9.0V. Results: 1) Early onset alopecia patients were more likly born in autum, had fewer siblings, and showed higher economical level of both patient and their parents than late onset patients. 2) Early onset alopecia patients were more likely to show diffuse hair loss, had more experienced past history of alopecia, more frequently had recurrence more than 3 times, were more severely damaged, had longer duration of hair loss had more loss of hairs on the vertex area at onset of alopecia, had more loss of hairs more than 2 areas, and had poorer prognosis such as no change or exacerbation in spite of treatment, spontaneous withdrawal of tratment and lack of efficacy to treatment than late onset patients. 3) Early onset alopecia patients were poorer in their adjustment in family life, or interpersonal relations, and more suffered from school stress such as changes of school life or test stress related with school entrance examination than late onset patients. 4) Early onset alopecia patients were more likely to show erious psychopathlology such as increased rate of the anxiety disorders, of anxiety symptoms or depressive symptoms, and of personality disorders including the hitrionic or the passive traits than late onset patients. 5) Early onset alopecia patients were more likely showed dermatits including seborrheic dermatits, and more significantly responding to the tratment with anti-anxiety drug, such as alprazolam, and dermatological therapies including polytar or tretinin than late onset patients. Conclusions: These findings suggest that dermatologists, as primary care physicians, are in unique position to recognize psychiatric comorbidity and to execute earlier intervention, in collaboration with psychiatrists, of early onset alopecia patients.

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