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      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • SCOPUS

        Critical Temperatures for Initiating and Arresting Delayed Hydride Cracking in a Zr-2.5Nb Pressure Tube

        Kim, Young Suk,Im, Kyung Soo,Cheong, Yong Moo Trans Tech Publications, Ltd. 2005 Key Engineering Materials Vol.297 No.-

        <P>The hydrogen concentration limit and critical temperatures for a delayed hydride cracking (DHC) in zirconium alloys have been reanalyzed using Kim’s DHC model that a driving force for DHC is not the stress gradient but the supersaturated hydrogen concentration or ∆C arising from a hysteresis of the terminal solid solubility on a heating and on a cooling. The DHC initiation occurs generally at the temperatures corresponding to the terminal solid solubility for precipititation (TSSP), demonstrating that the supercooling from the terminal solid solubility for dissolution (TSSD) is required to initiate the DHC. The DHC arrest temperatures correspond to the temperatures where the ∆C is reduced to zero. Therefore, we conclude that the ∆C is the driving force for the DHC and that the Kim’s DHC model is feasible.</P>

      • KCI등재

        독일어 영어 동사구조 및 형태의 통계적 비교

        김순임,송경안 한국독일어교육학회 1998 외국어로서의 독일어 Vol.3 No.-

        Beim Lernen der Fremdsprache wird der Transfer der schon erwor-benen oder erlernten Sprache vorausgesetzt. Um Deutsch als zweite Fremdsprache effektiv zu lernen und zu lehren ist es notwendig, die lexikalische Struktur des Englischen, das bei uns als erste Fremd-sprache fungiert, zu kennen. Denn normalerweise denkt man, daβ die lexikalische Struktur der beiden Sprachen sehr ahnlich waren, weil sie historisch gesehen aus der gleichen Sprachfamilie, dem Germanischen, stammen. Aber durch den Vergleich der Lexik im Deutschen und Englischen wrid gezeigt, daβ die Struktur der englischen Worter eher dem Franzosischen, einer der romanischen Sprachen, nahesteht als dem Deutschen. In dieser Arbeit wird untersucht, wieweit die Verben der beiden Sprache in der morphologischen Struktur gleich oder unterschiedlich sind. Aus de statistischen vergleichsanalyse einer bestimmten Quantitat von deutschen und englischen Verben Verben stellen sich einige Phanomene Heraus: 1. In der Frequenz des wiederholten Auftretens der Verben zeigne die beiden Sprachen keinen groβen Unterschied und diesbezuglich tritt die durchschnittliche Produktivitat der Verben beider Sprachen fast gleich auf. 2. Im Englischen kommen die zweigliedrigen Verben haufig vor, die den zusammengesetzen Verben des Deutschen entsprechen. 3. In der analyse der zusammengesetzen Verben der beiden Sprachen ergibt sich, daβ die Durchschnittsproduktivtat der Morpheme der englischen Verben niedriger ist als die der deutschen Verben. Das bedeutet, daβ das Deutsche im Vergleich mit dem Englischen aus den relativ wenigen Morphemen viele Verben gestalten kann. 4. Die Morphemkombinationsmoglichkeit der deutchen Verben ist groβer als im Englischen. Das beruht darauf daβ die deutschen Morpheme verschiedene Funktionen haben. Beispielsweise kann ein Verbzusatzmorphem sowohl als Verbstamm, als auch als Grundverb fungieren. Dieses Merkmal bezieht sich auf fast dem gleichen Prozentsatz der durchschnittlichen Produktivitat der deutschen Verben wie beim Englischen. 5. Die Verbaffixe beider Sprachen ahneln sich fast nicht in ihrer Formen. Die Ahnlichkeit der Verbformen von dem Englischen und dem Deutschen betragt 20%, wobei der Prozentsatz der Affinitat zwischen englischen und franzosischen Verben doppelt hoch ist. Aus der Untersuchung konnen wir sagen, daβ sich die englische Sprache auf der lexikalischen Ebene dem Deutschen unahnlich entwickelt hat und daβ diese Tatsache zum Unterricht des Deutschen als zweiter Fremdsprache im Rahmen des Transfers des Englischen auf das Deusche erkannt werden muβ.

      • KCI등재

        민들레 잎과 뿌리 분말을 첨가한 설기떡의 품질 특성

        유경미,김세희,장정화,황인경,김경임,김성수,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

        In order to develop a dandelion (Taraxacum officinale) with natural food applications, the effects of dandelion leaves and roots powder content on the physical, textural and sensory properties of sulggidduk were examined. Dandelion powders of leaves and roots at 0, 1, 2 and 3% were added to the dandelion sulgidduk. In the dandelion roots powder in sulgidduk, the color intensity of L values and the values and moisture content decreased however, the sensory color intensity, dandelion flavor and overall acceptability increased with increasing the dandelion powder content. The sensory overall acceptability indicated the dandelion roots powder content at 3% had the highest overall and flavor scores. As the dandelion leaves content was increased, the moisture contents, lightness, adhesiveness and cohesiveness of sulggidduk decreased, while the sensory color intensity, sensory hardness, hardness of texture properties and dandelion flavor increased. The addition at 1% of the dandelion leaves powder content with the dandelion sulggidduk and the addition at 3% of the dandelion roots powder content with the dandelion sulggidduk showed the highest overall acceptability.

      • 이질아메바에 의한 인체 대장상피세포주 HT-29에서의 interleukin-8 유전자의 발현

        김정목,정현채,임경일,조양자,김정룡 INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1995 YONSEI REPORTS ON TROPICAL MEDICINE Vol.26 No.1

        이질아메바에 의한 장염 환자의 조직 또는 이질아메바를 실험적으로 감염시킨 동물의 조직 검사에서 호중구의 침윤이 특징적으로 관찰된다. 그러나 이와같은 호중구의 침윤을 설명할 수 있는 기전에 대한 연구는 매우 미흡하다. 따라서 본 연구자들은 아메바 감염 초기에 인체 대장상피세포에서 interleukin-8(IL-8)이 유도되어 호중구 침윤과 같은 염증반응이 유발될 것이라는 가설을 설정하였다. 이를 위하여 인체 대장상피세포주인 HT-29에 이질아메바 영양형을 실험적으로 노출시킨 뒤 발현되는 IL-8 mRNA를 역전사 중합효소법(reverse transcriptional polymerase chain reaction, RT-PCR)으로 검사함과 동시에 발현된 IL-8 mRNA를 인공적으로 합성시킨 표준 RNA와 RT-PCR법을 이용하여 정량하였다. 실험 결과 이질아메바 영양형에 노출된 30분 후 부터 IL-8 mRNA가 발현되기 시작하였다. 그리고 그 발현 분자수는 노출 시간의 증가에 따라 계속 증가하여 3시간 대에는 3.1×10(7) molecules/㎍ total RNA를 나타내었다. 동시에 IL-8 mRNA의 발현은 노출시킨 이질아메바 영양형의 수에 비례하였다. 즉, HT-29/아메바 영양형의 비율이 10:1인 경우 IL-8 mRNA의 발현 분자수는 1.2×10(7) molecules/㎍ total RNA로 나타났다. 이와같은 IL-8 mRNA의 발현은 IL-8 단백질 분비로 이어짐을 ELISA 검사로 확인할 수 있었다. 한편 이질아메바 파쇄액(lysate)도 대장상피세포주인 Caco-2에서 IL-8 mRNA발현을 유도하였다. 결론적으로 본 실험은 이질아메바 감염 초기에 대장상피세포로 부터 IL-8이 발현되며 이에 의하여 염증반응이 촉발될 가능성이 있음을 시사해 준다. The protozoan parasite, Entamoeba histolytica, is one of major causative agents of intestinal disease all over the world. In acute experimental infection, the early host response to E. histolytica is characterized by an infiltration of neutrophils. However, the chemotactic signal for this response is not well known. Based on the finding that human epithelial cells produce the potent neutrophil chemoattractant and activator, interlukin-8 (IL-8), IL-8 gene expression was examined thoroughly in human colon epithelial cells exposed to E. histolytica trophozoites. Cellular RNAs were extracted from HT-29 or Caco-2 human colon epithelial cells exposed to E. histolytica trophozoities for 30 minutes. 1 and 3 hours. IL-8 mRNA transcripts were measured by reverse transcriptional polymerase chain reaction (RT-PCR) using synthetic standard RNA. The number of IL-8 mRNA molecules increased from 30 minutes to 3 hours of exposure period, reaching 3.1×10(7) molecules/㎍ of total RNA. Expression pattern of IL-8 mRNA transcripts was parallel to the amounts of IL-8 protein measured by enzyme-linked immunosorbent assay (ELISA). Lysates of E. histolytica also induced expression of mRNA for IL-8 in colon epithelial cells. These results suggest that acute inflammatory reaction by E. hisstolytica may be initially triggered by proinflammatory cytokines such as IL-8 secreted from epithelial cells of the colon.

      • KCI등재
      • 표면 플라즈몬 공명 신호의 증폭을 위한 새로운 금 콜로이드 센서칩 제조와 특성 연구

        임정혁,이경호,고광락,강신원,김재호 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        New gold colloidal film sensor chips were employed to enhance the sensitivity of the Surface Plasmon Resonce (SPR). Au collodal solutions were synthesized, and Au colloidal films were fabricated by immobilization of colloid on vacuum deposited Au film through the coupling agent of 1,8-diaminooctane. Specific interaction of human IgG antibody to human antigen was monitored by in situ SPR measurement from both a smooth and a Au colloidal films. Au colloidal film sensor chips resulted in 27 % enhancements effect for the same reaction on SPR angle shifts compared to a smooth Au film.

      • 소의 受精卵 移植에 관한 硏究 : II. 性成熟 過程의 처녀우의 多排卵 誘起와 受胎에 관한 硏究

        任京淳,李用斌,鄭丘敏,金鍾國 서울大學校 農科大學 1986 서울대농학연구지 Vol.11 No.1

        This experiment was carried out to investigate the effects of superovulation on the ovarian response and embryo production of young and matured heifers. The possibility of mon-surgical recovery from the young heifers and transfer of recovered embryos to the mature recipients was also investigated. A total of 8 heifers(5 heads of Holstein, 2 Heads of Korean Native Cattle(KNC)and one head of Angus×Hereford crossbreed)were devided into 2 groups by their age. Young heifers(Group I)were 7∼10 months old and mature heifers(Group II)were 12∼18 months old. Group I and II were superovulated with muscular injection of 1,000 or 2,000 IU Pregnant Mare's Serum Gonadotrophin(PMSG)on day 10∼12 of estrus cycle followed by muscular injecion of 25mg Prostaglandin F ₂α(PGF₂α) 48 hours later. Heifers were artificially inseminated or copulated 2∼3 times with the interval of 12 hours while they were in heat. The embryos were collected non-surgically on day 6 of estrus cycle. The results obtained from this study were summarized as follows: 1. The average number of corpus lutea(CL) by the superovulation treatment was much greater in Group 11(9.2)than in Group 1(3.2) 2. The average number of unruptured follicles by the superovulation treatment was much greater in Group II(6.8)than Group I(1.0) 3. The interval to onset of estrus after PGF₂αinjection was longer in Group I(44.2 hours)than in Group II(31.8 hours).

      • KCI등재후보
      • 현대 실내건축에 나타나는 역동적 디자인에 관한 연구

        김영숙,배경임 대구보건대학 2002 대구보건대학 論文集 Vol.22 No.-

        Depart from the past uniform and conventional frame, a space in the contemporary interior architecture makes interior space more dynamic through various dimension of space perception. The purpose of this study is to analyze the correlation of space perception and space form as a matter of dynamics, to understand a meaning of dynamics and dynamic element of design, and also to study a characteristic of dynamic design focused on space of contemporary interior design after 1980's. The results of this study can be summarized as follows. For characteristic of dynamic design, it was expressed in oblique and curved line in case of formative factor of mass; in transparency, immateriality, directionality and visual expandability in case of material factor; in transience and flexibility in case of concept of space-time, and in indeterminacy and continuity in case of program.

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