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      • 고속액체크로마토그래피에 의한 나프록센 광학이성질체의 분리 및 품질관리

        정수진,진전성,이은주,이은실,강종성 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-

        Enantiomeric separation of naproxen is necessary in drug evaluation processes as the pharmacological activity of naproxen resides mainly in the (S)-enantiomer, The enantioseparation of naproxen was carried out with three different stationary phases. The methods were validated with the terms of linearity, intraday and interday precision, accuracy, selectivity and recovery. Among the selected stationary phases, ChiroSil DMB column with hexane : t-butylmethylether : acetic acid (60:40:0.1, v/v/v) as mobile phase showed the best enantioseparation of the naproxen in the commercial preparations. The wavelength for detection was 270 nm and flow rate was 2.0 mL/min. The contents of (S)-naproxen in the commercial preparations were 92.7 - 98.3%, indicating that all tested preparations were satisfactory to current regulation. However, the contents of (R)-naproxen as impurity in the commercial preparations were varied from 0.08% to 1.08%.

      • KCI등재후보

        백내장 환자의 시기능지표 : 사전 연구를 중심으로 Pilot study

        강형곤,박은철,최윤정,김한중,홍영재,조우현,손명세,임승정 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.1

        Background : There is increased recognition that rigorous approach to functional assessment will complement the assessment of clinical status. This study is to develop the appropriate visual function index in Korean patients with cataracts by the assessment of the reliability, validity of visual function indexes including VF-14. Methods : An prospective study was performed with 92 patients who had undergone either one eye or both eye cataract surgery by 3 ophthalmologists practicing at a university-hospital. Patients were interviewed, and clinical data were obtained. Doctors were questioned with self-entered questionnaire forms. Medical record was examined to understand surgery-process. The survey was conducted at 1-2 days before cataract surgery. Results : We used following measures : 7 visual function indexes, global measures of patients' trouble and satisfaction with vision, and best-corrected visual acuity (VA) in each eye. 7 visual function indexes showed a high internal consistency reliability (Cronbach's alpha coefficients ≥0.86). The better visual acuity(operated eye. better eye), the higher patient satisfaction with vision, the lower symptom score, the lower patient trouble with vision was correlated with preoperative visual function index scores. Among 7 indexes, VF-12 with the exclusion of 2 items drivings from VF-14 is a high Cronbach's alpha coefficient and correlation coefficient and the highest R². Conclusion : We conclude that VF-12 is reliable and valid in Korea. So we suggest that in Korea, all items of VF-14, the visual function index, which is in use internationally, ought to be surveyed and VF-12 which has been excluded by 2 items of drivings from VF-14 ought to beused for analysis.

      • SCOPUSSCIEKCI등재
      • KCI등재후보
      • 패션산업의 신속대응(Quick Response)시스템 도입현황 및 도입사례에 관한 연구

        강희정,고은주 창원대학교 생활과학연구소 1997 생활과학연구 Vol.- No.1

        Environmental changes (e.g., threat of imports, rivalry among existing competitiors) have increased the difficulties in operating an apparel business. To manage the environmental changes, Quick Response System (QRS) has been proposed. QRS is defined as a business strategy to speed up the information and product between business partners for maximizing consumer satisfaction by information technologies(e.g., EDI, Bar code) and partnership (Ko, 96, VICS, 1989). The purpose of this study are to review the current development of QRS(i.e., background, concepts, benefits, adoption problems), to analyze two cases (in Japan and Korean), and to suggest the future directions for the new adopters of QRS. The information from this study can be used when apparel companies do strategic planning and evaluate the adoption of QRS. Informed decision are critical when companies do make a decision for the best choice.

      • KCI등재후보

        중환자의 욕창 예방 연구 : 욕창 예방 QI팀을 중심으로

        강소영,최은경,김진주,주미정 한국의료QA학회 1997 한국의료질향상학회지 Vol.4 No.1

        Background : A pressure sore was defined as any skin lesion caused by unrelieved pressure and resulting in damage to underlying tissue. The health care institutions in the United States were reported the incident rate of pressure sores ranging from 6 to 14%. United states were reported the incident rate of pressure sores in patients rate of pressure sore. Also, Annual expenditures for the care of pressure sores in patients in the United States have been estimated to be $7.5 billion; furthermore, 50 percent more nursing time is required to care for patients with pressure sore in comparison to the time needed to implement preventive measures against pressure sore formation. However, In Korea, there were little reliable reports, or researches, about incidence rates of pressure sore in health care institution including intensive care unit and about the integrated approach like CQI action team for risk assessment, prevention and treatment of pressure ulders. Therefore, this study was to develop pressure sore risk assessment tool and the protocol for prevention of pressure sore formation through CQI action team activities, to monitor incident rate of pressure sore and the length of sore formation for patients at high risk, and to approximately estimate nursing time for sore dressing during research period as the effect of CQI action team. Method : CQI action team in intensive care unit, launched since early 1996, reviewed the literature for the standardized risk assessment tool, developed the pressure sore assessment tool based on the Braden Scale, tested its validity, compared on statistics including incidence rate of pressure sore for patients at high risk. Throughout these activities, CQI action team was developed the protocol.called as St. Marys hospital Intensive Care Unit Pressure Sore Protocol, shifted the emphasis from wound treatment to wound prevention, After applied the protocol to patients at high risk, the incident rate and the period of prevention against pressure development were tested with those for patients who received care before implementation of protocol by Chi-square and Kaplan-Meier Method of Survival Analysis. Result : The CQI action team found that there was significant difference of incidence rate of pressure sores between patients at high risk( control group) who received care implementation of protocol (p<.05). 25% possibility of pressure sore formation was shown for the patients with 6th hospital day in ICU in control group. In experimental group, the patients with 10th hospital day had 10% possibility of pressure sore. Therefore, there was significant difference(p< .05) in survival rate between two groups. Also, nursing time for dressing on pressure sore in experimental group was deceased as much as 50% of it in control group. Conclusion : The collaborative team effort led to reduced incidence, increased the length of prevention against pressure sore, and declined nursing care times for sore dressing. However, there have had several suggestions for future study. The preventive care system for pressure sore should be appleed to patients at moderate, or low risk throughout continuous CQI team activities based on Bed sore Indicator Fact Sheet. Hospital-wide supports, such as incentives, would be offered to participants for keeping strong commitment to CQI team. Also, Quality Information System monitoring incidents and estimation cost of poor quality. like workload(full time equivalence) or financial loss, regularly in a hospital has to be developed first for supporting CQI team activities as well as empowering hospital-wide QI implementation. Being several limitations, this study would be one of the report cards for the CQI team activities in intensive care unit of an acute hospital and a trial of quality improvement of health care in Korea.

      • 미학과 사회적 이슈를 연계한 전시디스플레이 작품 연구 -저출산에 대한 인식 개선 프로젝트 "나쁜 엄마, 최고의 아빠"의 전시디자인 프로세스를 중심으로-

        강미선,박수빈,윤정원,오정은,이소원,이진민,신은별 숙명여자대학교 디자인연구소 2017 숙명디자인학 연구 Vol.23 No.-

        본 연구는 전시디스플레이 디자인 분야에 미학을 기반으로 예술적, 사회적, 디자인적 측면으로 다각적으로 접근하여 전시 디자인 분야의 색다른 코딩 프로세스를 체계화하고, 동시에 기존의 전시와는 차별화되는 새로운 전시 공간 프로세스를 제안하는데 목적이 있다. 본 연구의 대상은 2016년 9월-12월까지 15주간 숙명여자대학교 미술대학 환경디자인학과<전시디스플레이 디자인>교과목에서 진행된 프로젝트 중 일부이다. 본 연구의 과정은 총 3과정으로 이루어져 있으며, 미학적 개념과 사회적 문제, 전시관련 학문에 대한 이론적 고찰을 한 뒤 이를 전시디자인에 코딩하는 작업을 선행하였다. 두 번째로는 코딩한 작업을 바탕으로 전략적 모티브를 빛으로 선정하고, 전시디자인 전략게획을 진행하였다. 마지막으로 자료를 바탕으로 만든 스토리텔링을 기반으로 전시전개구성을 하고 이를 통해 스토리가 있는 차별화된 공간구성을 하였다. 로고디자인, 포스터디자인, 리플렛디자인, 영상 디자인 등 전시디자인 E.I작업을 통해 전시를 표현하였다. 끝으로 본 연구는 '미학 + 사회문제 + 전시디자인의 코딩'이라는새로운 창의적 전시 디자인 프로세스를 제안하였고, 이는 미학과 사회문제의 이론적 고찰을 반영한 전시디스플레이 프로세스 개발에 있어 향후 기초 자료로 활용될 것으로 기대한다.

      • 한국 수출제조기업의 마케팅역량이 수출성과에 미치는 영향 : 시장지향성과 인터넷 마케팅 효과를 중심으로

        강낙중,송은주 국제무역학회 2003 국제무역연구 Vol.9 No.2

        시장지향성과 성과와의 관계를 고찰한 문헌은 묵시적으로 시장지향성이 강한 기업이 그렇지 않은 기업에 비해 상대적으로 마케팅 역량이 뛰어날 것으로 전제하고 있다. 그러나 시장지향성과 성과와의 관계속에 내생변수로 존재하는 마케팅 역량을 고려한 연구는 국내에서 거의 전무한 실정이다. 이러한 사실에 착안하여 본 연구는 수출제조기업의 시장지향성이 수출성과에 미치는 영향을 분석함에 있어 마케팅 역량을 내생변수로 하는 모형을 검증하면서, 최근 새롭게 대두된 인터넷 마케팅과 기업규모의 영향을 고려한 연구모델을 설정하였다. 60개 한국 수출제조업체들을 대상으로 한 분석결과, 시장지향성은 마케팅 역량에 정의영향을 미치는 것으로 나타났으며 인터넷 마케팅은 이러한 관계를 강화시키는 것으로 나타났다. 한편 마케팅 역량은 수출성과에 정의 영향을 미치는 것으로 나타났으나 기업규모의 중재역할은 유의하지 않은 것으로 분석되었다. Despite the recognition of the importance of international operations for firms' survival and growth, almost no empirical research has been devoted to examining the relationships between market orientation and export performance. In addition, although firms have been rapidly integrating the internet into their marketing activities, no empirical research has focused on the potential mediating role of internet marketing on the consequences of market orientation. Also, although some research has related finns' distinctive marketing competencies to their strategic typology, none has attempted to relate marketing competencies to market orientation. Under these circumstances, this study construct a synthesized model of market orientation, marketing competence, and export performance, focusing on the mediating roles of internet marketing and firm size m these relationships. Then data for this study were collected from 60 export manufacturing finns in Korea and suitable statistical methodologies were employed for analysis.

      • 교량 기초부의 세굴에 관한 연구

        강정훈,이은태,이도훈 경희대학교 산학협력기술연구원 2000 산학협력기술연구논문집 Vol.6 No.-

        The most common cause of bridge failure stems from floods. The scouring of bridge foundation is the most common cause of flood damsge to bridges. The need to minimize future flood damage to the nation's bridges requires that additional attention be devoted to developing and implementing improved procedures for designing and inspecting bridges for scour. Statistically, we can expect thousands of bridges to experience floods on the order of magnitude of 100-year flood or greater each year. Because it is not economically feasible to construct all bridges to resist all conceivable floods or to install scour countermeasures at all existing bridges to ensure absolute invulnerability from scour damage, some risks of failure may have to be accepted from future floods. However, every bridge over a stream, whether existing or under design, should be assessed as to its vulnerability to floods in order to determine the prudent measure to be taken. The added cost of making a bridge less vulnerable to scour is small when compared to the total cost of a failure which can easily be two or three times the cost of the bridge itself. Moreover, the need to ensure public safety and to minimize the adverse effects resulting from bridge closures requires our best efforts to improve the state-of-practice for designing and maintaining bridge foundation to resist the efforts of scour.

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