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이경엽,백승찬,김성호,한동로,배장호,고삼규,김오룡,지용철,최병연,조수호,신현진 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.7
일상생활에서 피폭될 수 있는 전자기파로 뇌세포 손상 여부를 측정하기 위하여 2.45GHz 대역의 주파수를 이용하여 피폭량(10분-2.4joule, 20분-4.8joule, 30분-7.2joule)과 피폭후 시간경과(피폭 즉시, 1주, 2주, 4주후)에 따라서, 가토 36마리에서 전자기파를 조사한 후 가토의 뇌조직 손상정도를 측정한 바, 전자기파 조사후 신경 세포체, 수초신경섬유 및 무수초신경섬유에 일어난 변화는 사립체의 종창, 신경세포체와 신경섬유의 종창 및 공포형성이 나타났으며 이들 변화는 피폭량에 따라 비례하여 조직 변성이 심하였으나, 피폭후 시간이 흐름에 따라 대부분 가역성 변화를 나타내었다. 그러나 무수초신경섬유에서는 조사량에 따른 조직의 변화가 더욱 현저하게 나타났으며, 시간경과에 따라 가역성 변화 즉 회복의 정도는 역시 가장 미미하였다. 본 실험에서 전자기파의 피폭으로 신경세포의 손상을 확인 할 수 있었고, 이는 전자기파의 피폭양에 따라 뇌실질의 변화가 심하게 나타났으며, 특히 무수초신경섬유에서 손상의 정도가 심한 것을 밝혀졌다. 이들 변화는 대부분 시간경과에 따라서 세포자체의 가역성으로 회복되는 것을 증명할 수 있었다. The author measured the serverity of brain damage of 36 rabbits irradiated 2.45 GHz microwave for 10 minutes, 20 minutes and 30 minutes, respectively. Electromicroscopic and light microscopic findings of just after, Lweek, 2 weeks and 4 weeks after irradiated brain were compared in each time. Swelling and vacualization of nerve cell and mitochondria were noted. Also these changes tend to increased seventy along amount of radiation, but revealed reversible changes with time. Myelinated and unmyelinated nerve fibers were examined as same manner. These nerve fibers also revealed swelling and vascuolization, these findings also tend to increase severity with irradiation power and more prominent at unmyelinated nerve fibers. Reversability of these findings after each time period were more prominent in myelinated nerve fibers than unmyelinated nerve fibers.
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3,913례 요추간판탈출증 환자의 외과적치료에 대한 임상분석
최창락,박성찬,박해관,조경근,박영섭,이길송 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.6
Lately, surgical treatment for lumbar disc herniations has advanced markedly with new improvements of neurosurgical procedures using microscope and microinstruments. The following is the authors' report of the surgical outcomes of 3.913 consecutive patients with lumbar disc herniations treated during a 23-year period. These patients received treatments of laminectomy, hemilaminectomy or partial laminectomy with or without discectomy. After 1987, we also performed microdiscectomies using microscopes and microinstruments. The ratio of male to female was 71% to 29% and the fourth and fifth decades were most common with respect to age distribution. The causes of herniated discs include lifting, traffic accidents, falls or slipping, and sports. Almost all patients had complained of low back pain and leg pain(99%), and 81% had radicular pain or sensory abnormality in a dermatomal distribution. The diagnosis was made by lumbar myelogram, CT scan and/or MRI. Complications were developed in 6.2% of the surgical cases. Several conclusions can be drawn from the above indicated results of this series : 1) male patients predominate in the lumbar disc herniation which are most common in the fourth and fifth decades ; 2) the incomplete herniation of disc was common ; 3) MRI had the highest specificity as a single diagnostic tool, while the combination of myelogram. CT scan and MRI seems to be the best diagnostic method ; 4) almost all patients had low back pain and leg pain and 90% of the patients were positive in Laseque test ; 5) microdiscectomy is the most recomended treatment for lumbar disc herniations ; 6) The complication rate was 6.2% and the failed back surgery syndrome was most common.
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척주와 흉곽을 침범한 악성 종양에 대한 흉곽절제술과 일괄 척추체 절제술
노태훈,김긍년,윤도흠,하윤,이성 대한척추신경외과학회 2009 대한척추신경외과학회지 Vol.6 No.3
We performed combined spondylectomy for 2 patients of malignant tumors invading spinal column and chest wall. For one patient with Pancoast tumor, anterolateral thoracotomy, apical lobectomy, chest wall resection, and hemispondylectomy were performed. For another patient with solitary metastatic tumor from nasopharyngeal cancer, posterolateral thoracotomy, chest wall resection, and total en bloc spondylectomy were performed with anterior and posterior instrumentation. The tumor including invaded chest wall and spinal column werewas removed completely in both patients. No local recurrence was found at 18 months follow-up evaluation in both patients. We performed combined spondylectomy for 2 patients of malignant tumors invading spinal column and chest wall. For one patient with Pancoast tumor, anterolateral thoracotomy, apical lobectomy, chest wall resection, and hemispondylectomy were performed. For another patient with solitary metastatic tumor from nasopharyngeal cancer, posterolateral thoracotomy, chest wall resection, and total en bloc spondylectomy were performed with anterior and posterior instrumentation. The tumor including invaded chest wall and spinal column werewas removed completely in both patients. No local recurrence was found at 18 months follow-up evaluation in both patients.
