골반 내 농양 1예

조인숙,이해혁,김태희,이권해,남계현,이임순,김정식,박성진 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Pelvic inflammatory disease (PID) is a disease that affects young, sexually active, reproductive age women. Most pathogens are Chlamydia trachomatis and Neisseria Gonorrheae transmitted sexually. One of serious acute complication of PID is tubo-ovarian abscess (TOA) that involves the fallopian tube, ovary and adjacent structures (eg, bowel, pelvic peritoneum). The microbiology of TOAs is polymicrobial with anaerobic organisms and causal organisms of PID. Common anaerobic organisms are Peptostretococcus spp, Bacteriodes spp, Prevotella spp, Escherichia coli and aerobic streptococci. Treatment is necessary to admission for intravenous broad-spectrum antibiotics and surgery is often reserved for patients with suspected rupture or patients who fail to respond to antibiotics. So, we reported this case found pelvic abscess due to ruptured tube-ovarian abscess.

심초음파로 결정된 응급 심낭천자술의 천자부위

김성환,황성오,이강현,조준휘,강구현,문중범,이승환,윤정한,최경훈,김영식 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: The aim of this study was to determine whether the conventional subcostal approach is suitable for emergency pericardiocentesis in patients with cardiac tamponade or impending cardiac tamponade. Methods: This study was a prospective, observational study conducted at the emergency department of a tertiary hospital, Patients who had symptomatic pericardial effusion and who needed emergency pericardiocentesis in the emergency department were included in this study. We measured the epicardium-to-pericardium distance at the subcostal, parasternal, and apical area with two-dimensional echocardiography to determine the appropriate puncture site for pericardiocentesis. An epicardium-to-pericardium distance of more than 1.0 cm was considered as the primary safety factor in determining the Puncture site for pericardiocentesis. The skin-to-pericardium distance was considered as secondary safety factor. Results: Ninety-five consecutive patients(55 males and 40 females; total mean age: 53 year old) with cardiac tamponade or impending cardiac tamponade were enrolled in this study. The puncture site for pericardiocentesis, as determined by echocardiography, was the subcostal area in 43 patients(45%), the apical area in 40 patients(42%), the left parasternal area In 11 patients(12%), and the right parastemal area in one patient(1%). Pericardiocentesis failed in 2 patients(2%) with the subcostal approach and in one patient(1%) with the apical approach. The average epicardium-to-pericardium distance was 31 ±21 mm in patients with the subcostal approach and 21±8 mm in patients with other approaches. There were no differences in the amount of pericardial fluid and in the intraperical pressure among patient groups according to puncture site. There were two procedure related complications: a puncture of the right ventricle with the subcostal approach and a ventricular tachycardia with the apical approach.

産業間 資本構造差異에 관한 實證的 分析

朴筍植,趙成子 효성여자대학교 산업경영연구소 1990 경영경제 Vol.7 No.-

There are two perspectives about the affecting of capital structure of the value of the firm. One is irrelevancy theorem, the other is optimal capital structure theory. In irrlevancy theorem, capital structure has no effect on the value of the firm. In optimal capital structure, however, the value of the firm depends on the capital structure. In general, it is accepted that the latter is more valid under more realistic assumptions about the existence of bankruptcy costs and agency costs due to uncertainty in capital market. If optimal capital structure of individual firm exists, firms in the same industry have the same capital structure. If it is true, each industry has different capital structure by examing inter-industry differences in capital structure. For this purpose, cross-sectional analysis and time series analysis are used. The hypotheses tested in this study can be summarized as follows: <hypothesis> 1. H∧O : Firms in different industries have the same capital structure. H∧A : Firms in different industries have systematically different capital structure. 2. H∧O : The relative rankings of mean industry capital structure across time are random. H∧A : The relative rankings of mean industry capital structures across time are stable. 3. H∧O : The movement of a firm's leverage with respect to the industry mean is random. H∧A : The leverage of firms within an industry tends to converge to the mean industry leverage. For analysis, this thesis examined the capital structure of 9 industries covering 118 firms from1980 to 1987. For each industry in a given research term, the ratio of debt in the capital structure was calculated. Statistical tests methods, One-Way Analysis of Variance, Correlation Analysis, and Fisher Exact Probability test, is employed. We draw three major conclusions from these test results. First, capital structure of different industries in korea is highly significant at least between two industries, but pairwise tests which analyze the differences among various industries represent that differences between two industries is not statistically significant. Second, to analysis that the relative rankings of mean industry of capital structures across time are stable, correlation analysis is employed. As a result, the relative rankings of capital structures across time are not stable. For the third of this study, Fisher Exact Probability test is employed. The results show that the movement of capital structure of firms within an industry with respect to the industry mean is random

施肥量 및 施肥方法이 黃色種 담배 初期生育 및 收量에 미치는 影響

卞珠燮,趙成鎭,盧載榮,申周植 충북대학교 엽연초연구소 1984 煙草硏究 Vol.11 No.-

This experiment was carried out to study the effects of different amount of nitrogen and potassium applied and dressing methods on the growth and yield components of flue-cured tobacco The results are summarized as follows. 1.Growth was promoted by increased nitrogen level in the plot of high potassium application. 2.In the low level of nitrogen applications early growth was good in the plot of planting hole application, but there were little differences of growth among the treatments after middle part of maximum growth stage. 3.Weight per leaf area decreased by the increasing level of nitrogen with high potassium application. 4.Except the highest level of nitrogen (15㎏/10a), the weight per cured leaf was larder in the plot applied basal application 33 : first top dressing 33 : second top dressing 33 than in the plot applied 50 : 25 : 25. 5.Increased amount of potassium application made the leaf area contract ion ratio low and specific leaf weight high.

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

소아에서 나타난 비구개관낭의 치험례

모정희,정현구,조태식,김효석,박성규,이난영 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

The nasopalatine duct cyst is the most common non-odontogenic cyst in the oral area and is thought to be originated from the epithelial remnants of the nasopalatine duct. The nasopalatine duct cyst have been mentioned to be an overall incidence of 1.7-11.9% of all jaw cyst. More males than females are affected by that. It could occur all around the age, and especially in their 40th and 60th it happens the most and in childhood it is very rare. Proper treatment for nasopalatine duct cyst is enucleation. In the case of very large cysts, it is likely to be a risk of naso-oral or antral-oral fistulas or of devitalization of teeth, marsupialization is indicated. The purpose of case report is that a nasopalatine duct cyst in is very rare in childhood. A 9-year-old boy was referred to the chosun university pedodontics clinic that this child who has anterior palatal swelling is in routine check. The size of the cyst was so big that the marsupialization was committed and obturator was put. This patient is on the continuous observation. we treated the nasopalatine duct cyst with obturator.

주파수 선택성 레일리 페이딩 환경에서 부호화 기법을 이용한 직교 멀티캐리어 시스템의 오율 해석

정재필,박기식,한성운,조성준 한국항공대학교 1997 論文集 Vol.35 No.-

본 논문에서는 주파수 선택성 레일리 페이딩 환경에서 RS부호화, 컨벌루션 부호화, 연접부화를 이용하는 직교 멀티캐리어 BDPSK시스템과 QDPSK시스템의 오율특성을 구하였다. 오율특성은 정규화된 지연시간(??), 비트에너지 대 잡음전력 스펙트럼 밀도비(??), 희망 신호전력 대 지연되 비희망 신호전력비(D/U)를 파라미터로 하여 나타내었다. 검토한 결과, BDPSK 신호인 경우 D/U가 20[dB]일 대 오율을 ??으로 유지하기 위해 필요한 Eb/No는 Rs부호화, 컨벌루션 부호화 및 연접부호화에서느 각각 대략 20.8[dB], 16.0[dB], 14.5 [dB]가 필요하며, QDPSK신호인 경우 Rs부호화, 컨벌루션 부호화 및 연접부호화에서 각각 대략 24.0[dB], 18.9[dB], 13.5[dB]가 필요함을 알 수 있었다. This paper has evaluated the error performance of orthogonal multicarrier BDPSK and QDPSK systems which use Reed Solomon coding, convolutional coding, and concatenated coding technique in a frequency selective Rayleigh fading environment. The results show that when D/U (desired wave's power to undesired delayed wave's power ratio)=20dB at error rate of ??, Reed Solomeon coded BDPSK signal, convolutional coded BDPSK signal, and concatenated coded BDPSK signal need about 20.8[dB], 16.0[dB], 14.5[dB] respectively in terms of Eb/No, and Reed Solomon coded QDPSK signal, convolutional coded QDPSK signal, and concatenated coded QDPSK signal need about 24.0[dB], 18.9[dB], 13.5[dB] respectively.

황국균과 백국균의 대두 코지제조중 키토산의 효과

정순택,문길만,조건식,강성국,김설희 木浦大學校 工業技術硏究所 1998 工業技術硏究誌 Vol.8 No.-

The effect of chitosan in soybean koji preparation and characteristics of chitosan-koji were investigated. Aspergillus oryzae KCTC 6096 and Aspergillus kawachii KCCM 11458 was used for koji preparation. a-Amylase activity of soybean koji prepared with 0.25% 10cp chitosan was excellent relative to 30 cp chitosan and 1.6 times higher than non-added soybean koji. Acid and neutral protease activities of soybean koji prepared with 0.25%, 10 cp chitosan were showed simillary higher value than non-chitosna added koji. The period of koji preperation was reduced 30% by adding chitosan.

마우스 EAE, GVHD 질환에서 CTLA4Ig 융합단백의 면역치료 효과

장성옥,홍수종,조훈식,정용훈,Jang, Seong-Ok,Hong, Soo-Jong,Cho, Hoon-Sik,Chung, Yong-Hoon 대한면역학회 2003 Immune Network Vol.3 No.4

Background: CTLA4 (CD152), which is expressed on the surface of T cells following activation, has a much higher affinity for B7 molecules comparing to CD28, and is a negative regulator of T cell activation. In contrast to stimulating and agonistic capabilities of monoclonal antibodies specific to CTLA-4, CTLA4Ig fusion protein appears to act as CD28 antagonist and inhibits in vitro and in vivo T cell priming in variety of immunological conditions. We've set out to confirm whether inhibition of the CD28-B7 costimulatory response using a soluble form of human CTLA4Ig fusion protein would lead to persistent inhibition of alloreactive T cell activation. Methods: We have used CHO-$dhfr^-$ cell-line to produce CTLA4Ig fusion protein. After serum free culture of transfected cell line we purified this recombinant molecule by using protein A column. To confirm characterization of fusion protein, we carried out a series of Western blot, SDS-PAGE and silver staining analyses. We have also investigated the efficacy of CTLA4Ig in vitro such as mixed lymphocyte reaction (MLR) & cytotoxic T lymphocyte (CTL) response and in vivo such as experimental autoimmune encephalomyelitis (EAE), graft versus host disease (GVHD) and skin-graft whether this fusion protein could inhibit alloreactive T cell activation and lead to immunosuppression of activated T cell. Results: In vitro assay, CTLA4Ig fusion protein inhibited immune response in T cell-specific manner: 1) Human CTLA4Ig inhibited allogeneic stimulation in murine MLR; 2) CTLA4Ig prevented the specific killing activity of CTL. In vivo assay, human CTLA4Ig revealed the capacities to induce alloantigen-specific hyporesponsiveness in mouse model: 1) GVHD was efficiently blocked by dose-dependent manner; 2) Clinical score of EAE was significantly decreased compared to nomal control; 3) The time of skin-graft rejection was not different between CTLA4Ig treated and control group. Conclusion: Human CTLA4Ig suppress the T cell-mediated immune response and efficiently inhibit the EAE, GVHD in mouse model. The mechanism of T cell suppression by human CTLA4Ig fusion protein may be originated from the suppression of activity of cytotoxic T cell. Human CTLA4Ig could not suppress the rejection in mouse skin-graft, this finding suggests that other mechanism except the suppression of cytotoxic T cell may exist on the suppression of graft rejection.

생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구

김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.