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이승환,박병문,송경섭,이수건,윤상필,이재철,이범석,양봉석 대한척추외과학회 2017 대한척추외과학회지 Vol.24 No.1
Study design: Retrospective study. Objectives: The goal of this study was to evaluate the risk factors of osteoporotic vertebral fractures (OVFs) in patients with Cushing syndrome. Summary of Literature review: In most reports, vertebral fractures in Cushing syndrome have been found to be related to osteoporosis. However, few studies have analyzed the clinical risk factors for OVFs. Materials and Methods: Thirty-two patients with Cushing syndrome who visited the orthopaedic department complaining of back pain were included in this study. Standing lateral X-rays were performed to evaluate the presence of vertebral fractures, and bone mineral density (BMD) was measured. Results: Of the 32 patients with Cushing syndrome with back pain, 8 (25%) were diagnosed with OVFs using morphometric criteria. The average weight and body mass index of the vertebral fracture group (VF group) were significantly higher than the values observed in the non-vertebral fracture group (non-VF group) (p=0.004, p=0.018). Lumbar BMD was significantly lower in the VF group (p=0.006). A risk factor for OVFs in Cushing syndrome was osteoporosis (odds ratio=18.56, 95% confidence interval=1.72-200.21, p=0.016) regardless of gender, obesity, menopause, or urine free cortisol levels. Conclusions: OVFs in Cushing syndrome have been associated with overweight, and overweight is an indicator of compliance in the treatment of Cushing syndrome. Therefore, weight reduction and the prevention of osteoporosis should be emphasized in patients with Cushing syndrome to prevent OVFs. 쿠싱 증후군에서 골다공증성 척추 골절의 위험 인자이승환 • 박병문 • 송경섭 • 이수건 • 윤상필 • 이재철 • 이범석 • 양봉석광명성애병원 정형외과연구 계획: 후향적 연구목적: 쿠싱 증후군에서 증상이 있는 골다공증성 척추 골절의 유병률을 조사하고, 골다공증성 척추 골절의 위험 인자를 분석하였다. 선행문헌의 요약: 쿠싱 증후군에서 척추 골절은 대부분은 골다공증과 연관이 있었다. 그러나 척추 골절의 다른 위험 인자에 대해 분석한 연구는 거의 없었다. 대상 및 방법: 요통으로 정형외과 외래에 내원한 32명의 쿠싱 증후군 환자를 대상으로 하였다. 흉요추부 기립위 측면 방사선을 촬영하여 척추 골절을 진단하였고, 척추와 대퇴 경부의 골밀도를 측정하였다. 척추 골절 그룹과 비골절 그룹의 통계학적 차이를 paired t-test를 이용해 비교하였고, 위험인자 분석을 위해 로지스틱 회귀 분석을 사용하였다. 결과: 전체 32명의 환자중 8명(25%)의 환자에서 골다공증성 척추 골절이 확인되었다. 척추 골절군의 평균 체중과 체질량 지수가 비골절군에 비해 유의하게 높았으며(p=0.004, p=0.018), 척추 골절군의 요추부 골밀도가 비골절군에 비해 유의하게 낮았다(p=0.006). 골다공증성 척추 골절의 위험 인자는 골다공증으로 나타났다(odds ratio 18.56, 95%CI 1.72-200.21, p=0.016). 결론: 쿠싱 증후군 환자에서 척추 골절의 발생은 과체중과 관련이 있으며, 과체중은 평소 쿠싱 증후군의 부적절한 치료로 인한 상태를 반영하는 지표라고할수 있다. 그러므로, 적절한 내분비적 치료를 통계 적정 체질량을 유지하고, 골다공증의 약물 치료를 병행하는 것이 쿠싱 증후군의 척추 골절 예방에 중요하다고 하겠다. 색인 단어: 쿠싱 증후군, 척추 골절, 골다공증약칭 제목: 쿠싱 증후군과 척추 골절
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이승환 金烏工科大學校 2000 論文集 Vol.21 No.-
The needs for the installation of artificial reefs are rapidly increasing due to the change of fishery policies in Korea. Little follow-up after the setting of artificial reefs, however, had been performed and no studies were conducted to investigate the effects of releasing material from concrete-made reefs. In this study, analytical comparison for the releasing material from laboratory-scale stoney-pellet and concrete reefs was made. The sea water pH and temperature at concrete reef tank kept higher than those from stoney-pellet ones by 1.2 to 1.5 due to the continual release of Ca^2+, and by 1.0 to 3.0 oC due to hydrolysis. The release of harmful inorganic materials and heavy metals from both artificial reefs were negligible. Based on the analytical results, possible changes of ecosystem around the reefs were predicted and proposals were made for the effective management of the artificial reefs.
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유도전동기의 자속제어형 Inverter에 의한 가변속 운전
이승환,우정인,이준탁 동아대학교 공과대학 부설 한국자원개발연구소 1987 硏究報告 Vol.11 No.2
Many techniques for variable speed drives of induction motor had been introduced. Recently, all of them are replaced by PWM control techniques with transitor inverter. But the troublesome problems appeared in variable speed drives include the determination of PWM switching patterns, the generation of control signals, the minimization of torque pulsation, acoustical noises, mechnical vibrations, harmonics and etc.. Therefore, the pursuits of high performance drives and compactness in control circuits without the aids of micro-computer or micro-processor with the functions of control and simple calculations are impossible. In this paper, one technique for the digital and software processing of all control factors is introduced. The determinations of PWM switching patterns are based on the selection of flux vector equivalent to the integral value of applied voltage during every sampling period. And, the real flux vector is controlled so that the trajectory of it can be tracked to the circularform one of ideal flux vector. Also, introduction of the concept of g-u-w plane from d-p plane make digitization and quantization of all control factors convenient. Specially, the predicted control techniques in selection of differential flux vector, Δλ, have functions which can compensate the delay time due to the micro-processor processing, so the real time control system by 8086 micro-processor, simulation and experimental results are in detail compared each other.
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Topiramate의 기분안정 효과 및 체중감소 효과 : 사용 1례 A case report
이승환,정영조 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3
Topiramate is a novel antlepileptic agent with a wide spectrum mechanism of action, and recent reports indicate that it may have mood stabilizing properties in bipolar disorder. We experienced topiramate treatment of a 38 years old woman with bipolar disorder who had 5 previous hospitalizations for mood unstability during past 4 years. For the past 4 years, she had been treated with lithium, carbamazepine and valproate as well as small dosages of antipsychotics. But her treatment responses were not good enough because of weight gain and incomplete mood stabilizing effects of previous medications. We used topiramate for the recent new manic episode. During 8 weeks of trial, topiramate was well tolerated. and her mood was better stabilized than ever. The patients, now on 1000㎎/4ay of topiramate is mostly asymptomatic, and her weight was reduced from 68㎏ to 62㎏, and has functioned well for over 3 months.
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