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민병무,김용백,박근성,송규상,양준묵,이성복,조항진,길숙종,김승영,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
An improved retinal tack can be used to fix the retina in complicated retinal detachment and proliferative vitreoretinopathy. We used the retinal tack made by biodegradable polyglycolic acid, polylactic acid and copolymers. The tacks with polyglycolic acid were placed in the retina the right eyes of 10 rabbits as group 1, with polylactic-polyglycolic acid copolymers as group 2 in each left eyes. We examined the absorption rates and degree of intraocular inflammation at 1 day, 1, 2, 4, and 8 weeks and compared both eyes. The tacks were absorbed with time in both eyes, but more rapid in copolymers. And there was no inflammation in both eyes. Now, this study will be a base on the drug delivery system in intraocular pharmacological and surgical management.
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염화제1구리를 함침시킨 활성탄 고정 흡착층의 CO 및 CO2 흡착특성
민병무,유기풍,김성현 ( Byoung Moo Min,Ki Pung Yoo,Sung Hyun Kim ) 한국화학공학회 1994 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.32 No.2
Adsorption characteristics of CO and CO₂ gases for a fixed-bed adsorber filled with 37 wt% CuCl-impregnated activated carbon were measured. We found that the amount of equilibrium adsorption of CO₂ is less than that of CO on the adsorbent. Accordingly, the breakthrough point of CO₂ was reached earlier than the case of CO. As a result, we concluded that the adsorbent prepared in this work can possibly be used to selectively separate CO from the mixture of CO and CO₂ gases. Also, the experiment showed that the behavior of breakthroughs mainly depend on bed temperature and gas flowrate rather than the concentration of component to be adsorbed. Finally, a method that can calculate adsorption characteristics of the bed was proposed based on the theory of FH-VSM equilibrium isotherm. The calculated adsorption behaviors agree well with the experiment.
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Indomethacin과 Dexamethasone이 Lipopolysaccharide에 의한 골흡수에 미치는 영향
민병무,정동균,김정근 대한구강생물학회 1985 International Journal of Oral Biology Vol.9 No.1
Present study ws undertaken to determine the inhibitory effects of indomethacin and dexamethasone on LPS-induced bone resorption. Bone resorption was assessed in the period of 24, 48 and 72 hours by the release of previously incorporated ^45Ca from the shafts of radii and ulnae of 20 day fetal rats after 200μCi of ^45CaCl_2 was injected subcutaneously into the mothers on the 18th day gestation. The shafts were pre-cultured for 24 hours in BGJb media supplemented with bovine surum albumine (1㎎/ml)in a atmosphere of 5% CO_2 in air at 37℃. One pair of bones were used for drug effects while the other pair from the same fetus served as control. The experimental bones were then transfered to the LPS-containing (1μg/ml) media to which one of these drugs was added (10^-7 or 10^-5M)and control bones to the only LPS-containing media and cultured for 72 hours. Two concentrations of indomethacin inhibited LPS-induced ^45Ca release after 48 and 72 hours, and in dexamethasone, only 10^-5M concentration inhibited it after 48 and 72 hours. It is speculated that the inhibitory effect fo indomethacin or dexamethasone on LPS-induced bone resorption may be due to the inhibition of prostaglandin synthesis induced by LPS.
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