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오소희,권순원,김종수,김용기,임헌송 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2
Ectodermal dysplasia(외배엽 이형성증)은 외배엽성 기관에 한가지 이상의 선천적 이상소견을 특징으로 하는 질환이다. Ectodermal dysplasia는 약 120종류 이상이 보고되고 있고, 이 중 Hypohidrotic ectodermal dysplasia가 가장 잘 알려져 있으며 이는 성염색체 열성인자에 의해 유전되며 남성에서 호발한다고 한다. 임상증상으로는 무한증, 감모증, 무치증 혹은 핍지증이 가장 특징적이다. 이외에도 무피지증, 손톱이형성증, 가늘고 성긴 머리카락, 두드러진 이마, 안장코, 돌출된 안와상부, 입술의 돌출과 함께 피부가 건조하고 땀샘이 결핍되어 있어서 더위를 참지 못하고 발열이 일어나기 쉽다. 본 증례의 환자는 단국대학교 치과병원 소아치과에 내원한 6세 6개월된 남아로써 무치증을 보이는 Hypohidrotic ectodermal dysplasia로 진단되었고 환자의 심미적, 기능적 결함을 해소하기 위해 총의치로 치료를 시행하는 동안 다소의 지견을 얻어 이를 보고하는 바이다. 주요어 : 외배엽 이형성증, 무치증, 총의치
임태규,한승기,남현우,이상건,오종배 한국뇌학회 2001 한국뇌학회지 Vol.1 No.1
본 연구에서는 내측두엽 간질(medial Temporal Lobe Epilepsy, m-TLE) 환자의 발작기 뇌파(ictal electroencephalogram; ictal EEG)를 ICA(independent component analysis)로 처리하여, 근육잡파(muscle artifact)를 비롯한 여러 잡파들의 영향이 제거된 원래의 두뇌신경계에 의한 뇌파를 재구성할 수 있음을 보였다. 또한, ICA로 추출된 4∼6Hz의 발작리듬(ictal rhythm)에 해당하는 독립성분들이 환자군에 따라서 좌우 측두엽으로 편측화된 결과를 얻었다. 이 결과를 이용하여, 좌우 측두엽에서 θ파의 파워를 편측화의 지표로서 사용할 수 있음을 보였다. In this paper, we show that various artifacts due to muscle activity or eye movement could be removed from the ictal electro-encephalogram(EEG) of medial temporal lobe epilepsy(TLE) patients using the independent component analysis(ICA). The ictal rhythms in the 4°≠6Hz are obtained, with the topographic maps localized to the left or right side temporal lobe according to the patient group. Using the power spectral density of the ictal rhythms, we show that the lateralization of m TLE is possible.
양성렬,최기오,박종근,류문희,홍석노,김수한,안봉환,이제혁,이민화 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.4
Protective effects of human cerebrospinal fluid antioxidants against enzyme inactivation caused by metal-catalyzed oxidation systems were investigated. When purified glutamine synthetase(GS) was incubated with human cerebrospinal fluid(CSF), the enzyme was progressively inactivated. Catalase and EDTA could inhibit the enzyme inactivation by 50-80%. Small-molecular(Mr< -10,000) fraction of CSF inactivated the exogenous GS, but large-molecular(Mr> -10,000) fraction did not. The GS inactivation by the small-molecular fraction was also markedly inhibited by catalase and EDTA. These results suggested that metal-catalyzed oxidation is involved in the GS inactivation by the small-molecular fraction of CSF. Dithiothreitol(DTT) was shown to inhibit almost completely the oxidative inactivation of GS by CSF. However, DTT inhibited only partially the oxidative inactivation of GS caused by small-molecular fraction of CSF. When large-molecular fraction of CSF was separated by anion-exchange HPLC chromatogrpahy, there was a peak of antioxidant activity inhibiting the small-molecular fraction-induced GS inactivation in the presence of DTT. The antioxidant activity was neutralized by monoclonal antibodies to transthyretin. Purified transthyretin was found to efficiently inhibit ascorbate/Cu^(2+)-induced GS inactivation in the presence of DTT. Uric acid and glucose did not show any protective effect on the GS inactivation in the same condition. The above results suggest that metal-catalyzed oxidation occurs normally in human CSF, and that transthyretin may play an important role as a CSF antioxidant in protecting proteins from metal-catalyzed oxidation.
Widely tunable multichannel grating cavity laser
Oh Kee Kwon,Jong Hoi Kim,Kang Ho Kim,Eun Deok Sim,Kwang Ryong Oh IEEE 2006 IEEE photonics technology letters Vol.18 No.16
<P>A widely tunable grating cavity laser based on the Rowland circle construction for a concave grating is proposed and demonstrated. The device is implemented by employing multichannel array structure in a Littman configuration and fabricated by integrating all elements in an InP substrate. Only one channel is turned on at a time, with coarse tuning realized by selecting the appropriate element in the channel array and fine tuning by controlling the beam deflection provided by dispersive element. An overall tuning range of 50 nm with a sidemode suppression ratio of more than 30 dB has been achieved for the six-channel device.</P>
조백기,박종갑,김형옥,김성욱,백승철,김진우,김시용,안규중,전재복,오지원,김낙인,이규석,오칠환,김수남,김상태,손숙자,신용우,김동석,이원우,권경술,서대헌,황규왕,이종석,고재경,강원형,정기양,최응호,김기홍,박석돈,강승주,함정희,명기범,김방순,구상완,김병수,원영호,김한욱,송은섭,정병수,노병인,홍창권,박장규,한지윤,김광중,구대원,김종민,김재홍,유희준,양경미 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2
Background: Onychomycosis, especially toenail onychomycosis has become one of the common fungal infection and has historically been regarded as a cosmetic rather than medical problem by many patients, even by physicians. Recently, however, there are several reports that is a refractory disease which may cause a deleterious effect on patiets quality of life (QOL). Objective: The purpose of this study was to investigate the impact of toenail onychomycosis on QOL in Korea and to assess the chandes of QOL after treatment. Methods: Total 1004 patients with toenail onychomycosis which was confirmed by clinical findings and KOH preparation were were enrolled at 47 dermatologic centers in Korea, and interviewed with standardized QOL questionnaire before and after sytemic antifungal treatment. Responses to the questionnaire were scored by 5-point scale (1∼4) and averaged, and were analyzed for 5 dimensions of emotional impact, social impact, symptorn and functional impact, patients views concerning treatment, and relationship with doctor. Results: 1. Before and after treatment, the most serious impact was emotional dimension showing 1.90 and 1.30 in average score (AS), and social (AS: 1.14 and 0.83) and symptom and functional impact (AS: 1.05 and 0.92) was also affected. 2. In female rather than male, statistically more significant impact on patients QOL was observed in all dimensions. 3. After treatment, 3 of 5 dimensions were improved significantly - emotional dimension (AS : from 1.90 to 1.30), social dimension (AS: from 1.14 to 0.83), patients view concerning treatment (AS: from 1.34 to 1.02). 4. The drgree of patients satisfaction at the therapeutic effect was very high- 62.4% (immediately after treatment) and 65.8% (9 months affer initiation of treatment) of patients answered excellent or good. Conclusion: This study confirms that toenail onychomycosis has significant impact on the overall QOL of patients. Also the effect of antifungal therapy on patients QOL were watisfactory. Therefore, both doctor and patient should pay more attention to the treatment of onychomycosis. [Kor J Med Mycol 3(1): 115∼124]
오정근 ( Jung-keun Oh ),박선오 ( Seon-oh Park ),김기헌 ( Ki-heon Kim ),이영기 ( Young-kee Lee ),오길종 ( Gil-jong Oh ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 한국폐기물자원순환학회지 Vol.36 No.2
The Ministry of the Environment Notification on the conversion of loading boxes for waste collection and transportation vehicles to a sealed form (MOE, Notice No. 2016-237). This has been enacted to keep boxes from being blown off by wind or from leaking, during the course of collection, transportation, or storage of waste. This Notification also includes specific gravity criteria by loading mode of waste collection and transportation vehicle with the function of dumping. The specific gravities of compressed and non-compressed mode vehicles are 0.300 and 0.200, respectively. However, the recycling business has a significant issue with regard to the collection or transportation of some recyclable material, e.g., plastic waste, which has small apparent specific gravity and uses a non-compressed mode vehicle, making it difficult to meet the criteria of the Notification. Therefore, it is important to establish a standard based on the actual measurement data by waste item. The aim of this study is to suggest practical specific gravity criteria for different loading modes in household waste collection and transportation vehicles by not only investigating the current situation of waste collection and transportation but also calculating the apparent specific gravity of recyclable materials when subjected to collection and transportation vehicles. In this study’s results, the apparent specific gravities of mixed recyclable materials within compressed and non-compressed mode vehicles are 0.230 and 0.082, respectively, indicating that the existing criteria in this Notification are set too high.