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      • KCI등재

        RELATIONSHIP BETWEEN THE WIENER INTEGRAL AND THE ANALYTIC FEYNMAN INTEGRAL OF CYLINDER FUNCTION

        Kim, Byoung Soo Chungcheong Mathematical Society 2014 충청수학회지 Vol.27 No.2

        Cameron and Storvick discovered a change of scale formula for Wiener integral of functionals in a Banach algebra $\mathcal{S}$ on classical Wiener space. We express the analytic Feynman integral of cylinder function as a limit of Wiener integrals. Moreover we obtain the same change of scale formula as Cameron and Storvick's result for Wiener integral of cylinder function. Our result cover a restricted version of the change of scale formula by Kim.

      • KCI등재

        RELATIONSHIP BETWEEN THE WIENER INTEGRAL AND THE ANALYTIC FEYNMAN INTEGRAL OF CYLINDER FUNCTION

        Byoung Soo Kim 충청수학회 2014 충청수학회지 Vol.27 No.2

        Cameron and Storvick discovered a change of scale for-mula for Wiener integral of functionals in a Banach algebra S on classical Wiener space. We express the analytic Feynman integral of cylinder function as a limit of Wiener integrals. Moreover we obtain the same change of scale formula as Cameron and Storvick s result for Wiener integral of cylinder function. Our result cover a restricted version of the change of scale formula by Kim.

      • KCI등재

        정신분열병에 대한 리스페리돈의 효과 및 안정성

        이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

        연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

      • KCI등재

        階段 오르기에 있어서 계단의 段 높이 差異에 따른 身體的 變化에 관한 硏究 : 血壓과 脈搏의 변화를 중심으로 Focus on the changing of pulse and blood Pressure

        김영수,강병근 대한건축학회 2003 대한건축학회논문집 Vol.19 No.4

        Now the stair height in building design is considered to comply with the building law and be applied to made to general detail plan s measure. However, Stair in modern building is very important as its complex function as well as simple function plays great role helping people stay physical balance and especially going up stairs in exercise concept. Although lots of study about stair has been making considering human physical features partially, it is not enough to satisfy the better stair environment conditions for people to use it yet. Therefore this is an experimental study about changing of pulse and blood pressure according to human physical fatigue in going up stairs because in case exceeding maximum blood pressure and pulse scope it can be able to work more dangerously in life than physical balance. Consequently the aim of this study is to consider about stairs table measure and offer fundamental materials for better nice stair space plan, based on survey about changing of pulse and blood pressure according to the difference of stair height in going up stairs of building. 1) When the experiment is progressed stepwise divided objects of the experiment into infants, elementary students, secondary school students, adults and the old, it is possible to calculate the appropriate measure about the stair height and stair width to each user for all kinds of buildings. 2) While exercising especially, continued diverse trial for calculating the appropriate measure of stairs considered the change scope of pulse and blood pressure, it is thought that we can gain fresh space constitution regarding the human technological aspect. 3) Form including going up stairs og buildings in the range of exercise, it come to the conclusion to be able to use for material, based on this.

      • 여드름 환자에서 adapalene 겔과 tretinoin 크림의 split-face 비교 연구

        김영조,선정우,정병수,최규철 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

        Background : Adapalene is a new synthetic naphtholic acid derivative with potent retinoid and antiinflammatory properties, developed for the topical treatment of acne vulgaris. Objective : This study was designed to compare the efficacy and safety of 0.1% adapalene gel with tretinoin cream(0.025% and 0.05%) in the treatment of grade I to V facial acne vulgaris. Methods : Forty acne patient volunteers were enrolled in this investigatormasked, left-right comparison, randomized, controlled, intraindividual study. 0.1% adapalene gel and tretinoin cream(0.025% or 0.05%) were applied once a day to one halfface by the volunteers for 30 consecutive days. Efficacy and cutaneous tolerance were accessed at baseline and week 1, 2, 3, and 4. Efficacy was determined by investigator counts of inflammatory papules and pustules, and non-inflammatory open and closed comedones, as well as global improvement. Clinical signs(erythema, desquamation, dryness) and subjective symptoms(pruritus, burning) were evaluated and scored weekly. Result : 0.1% Adapalene gel was more effective in treating acne lesions than tretinoin cream(p<0.05). Cutaneous side effect was limited to a mild retinoid dermatitis occurring in all treatment groups. However, patients treated with adapalene gel tolerated this therapy significantly better than those treated with tretinoin cream. Conclusion : 0.1% adapalene gel applied once daily was significantly more effective in reducing acne lesions and was better tolerated than tretinoin cream in the treatment of acne vulgaris.

      • 단독주택의 용도별 에너지 소비에 관한 연구

        김병수,장문석,박효순,송인춘 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1

        The purpose of this study is to analyze the situation of energy consumption and its characteristics in detached houses. The survey is carried out in detached houses to investigate the energy consumption and energy use trend in according to three different climate zones. Building energy simulation by DOE-2 computer program was undertaken for detailed analysis of the energy use characteristic in detached houses. Also, The room temperature and the energy use of the year were also calculated. Finally, The energy consumption characteristics of heating, cooling, cooking and electric equipments in detached houses depends on life style of resident such as room temperature, occupancy type and equipment operating schedule and etc. And also, the results of this study will be to provide basic data concerned with total energy consumption in detached houses.

      • 원형 비강진 1예

        김영조,박홍표,정병수,최규철 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

        Pityriasis rotunda is an uncommon cutaneous disorder consisting of asymptomatic, strikingly circular, scaly lesions on the trunk and extremities, with the histologic appearance of ichthyosis vulgaris. A case of pityriasis rotunda in a 35-year-old woman in whom no diagnosable disorder could be demonstrated is presented.

      • 폐비닐 재활용 여재를 이용한 소규모 오수종말처리장의 효율검증

        김병욱,임재명,구본수 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

        This study was conducted to use dicused vinly as biofilm for biological sewage treatment. Efficiency verification was performed on laboratory and on-site plant. In laboratory study, total biochemical oxygen demand(TBOD) removal rate was ranged 94.8~97 % in each hydraulic retention tim(HRT), 12, 16, 20, 24 hr, respectively. At that time, filling rate was 50%. And effluent TBOD concentration was low ranged 3.64~6.28hg/L. In on-site plant, TBOD removal rate was ranged 88.2~96.8% and effluent TBOD concentration wa s4.8~17.7mg/L. This concentration was lower than disign effluent concentration, 30mg/L. Total kjeldhal nitrogen (TKN)removal efficiency was ranged 56.8~90.9%. This was resulted higher than Lab. scale treatment efficency.

      • 가동보 설치에 따른 하상변동 예측에 관한 연구

        김운중,문수회,김영균,민병무 朝鮮大學校 建設技術硏究所 2007 建設技術硏究 Vol.27 No.1

        To estimate the change of riverbed geography by the operation of movable weir, two-dimensional RMA-2 and SED-2D were used in this study. Hydraulic elements like flowrate or depth were simulated by RMA-2 and the change of riverbed geography according to sediment transport was simulated by SED-2D. Suktop stream was chosen as a project river for the simulation. Under the condition of 50-year rainfall frequency, the estimated flood of Suktop was 123cms. At the points of movable weir the simulation results showed that the difference of high water level from the result of HEC-RAS was less than 0.64m. And the difference of water velocity was less than 0.21m/sec. Based on the sediment simulation by SED-2D, predicted riverbed elevation was 29.70-30.22m at the point of ST1 and 28.26~28.82m at the point of ST2. Measured riverbed elevation was 29.70-30.16m, 28.28-28.69m, respectively. So, the predicted elevations are closely similar to the measured elevation. At the point of ST1, sediment transport simulation results showed that erosion of riverbed was predicted by the operation of movable weir. This erosion was ranged up to 200m upstream and the riverbed would be eroded away as much as 0.07m for one year. At the point of ST2, upstream of movable weir would be eroded and the erosion depth was estimated 0.261m. The erosion was higher at the point of movable weir and the erosion depth was estimated 0.310m. But the sediment would be deposit downstream of the movable weir. SED-2D followed by RMA-2 is well applicable to the stream which has movable weirs and can estimate not only hydraulic parameters such as flowrate or depth but also riverbed elevation change caused by erosion or deposit of fluvial sediment.

      • RESEARCH INSTITUTE OF INDUSTRIAL TECHNOLOGY CHUNGNAM NATIONAL UNIVERSITY

        김병수,박상래,김기세,송인춘 忠南大學校 産業技術硏究所 1997 산업기술연구논문집 Vol.12 No.2

        As the use of hot water in multifamily housing in Korea increases, it is desirable to apply solar hot water(SHW) system into apartments to save energy used for hot water. The study aims to evaluate the energy saving sffect of the solar hot water collectors in multifamily housing. First, the energy costs for hot water in selected 31 pyung apartment were surveyed. Actual SHW system were installed and then the their performance in terms of water temperature and flow rate was monitored. Form the survey and the experiment it found that the use of the solar hot water system applied in the apartments contributes to the enegy saving ofabout over 10%

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