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      • 보안 신뢰성 평가모델의 적용에 관한 연구

        박지미,승현우,박미영 서울여자대학교 2010 정보기술논문지 Vol.8 No.-

        The field of software engineering has been doing a new research to find out a desirable security system with its established study because the significance of information security is recently getting bigger and bigger in modern technology. As a result, a number of challenges are being attempted to devise a new method which is able to evaluate the security degree of software, like reliability estimation model that has been the criterion of software to decide whether it is trustworthy or not. In this paper, the reliability growth model, which has been previously designed to estimate the reliability of software, will be discussed. In addition, the uppermost limit and the application plan of the reliability growth model falls within the ambit of this research when this model is being applied to the reliability estimation model.

      • 자가면역 용혈빈혈의 임상적 분석

        박치영,강지은,박상곤,김상현,김형선,정춘해 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Background: Autoimmune hemolytic anemia (AIHA) is a very uncommon disorder with the incidence between one and three cases per a hundred thousans a year. There have been very few studies about AIHA in Korea because of its low incidence. Most AIHA studies in Korea were about case history. The aim of this study was to review the clinical features, therapy and outcome of AIHA patients in single institution clinic. Methods: We reviewed retrospectively the medical records of AIHA patients from December 2002 to December 2006. Results: Twelve patient with AIHA were identified, and their median age was 49 years (range 27-75). Male to female ratio is 9:3. The median hemoglobin level was 5.0 g/㎗ (range 2.5-8.2). Warm type AIHA was most common (8/12), cold type was three, and mixed type was one. There was histories of associated disease in six patients. Two patients were complicated by systemic lupus erythematosus and mycoplasma infection and one patient by idiopathic myelofibrosis and solid tumor. Oral steroid was used as the first-line treatment in nine patients. An initial response was observed in eight patients with complete response. One patient had not responded to the initial steroid treatment, and then showed complete response with rituximab. Two relapsed patients were treated with rituximab and partial splenic embolization. Conclusion: The majority of patients can be treated with steroid. Rituximab can improve the response rate in relapsed and refractory AIHA.

      • 재발된 원발성 고환림프종이 동반된 류마티스 관절염 환자에서 Rituximab으로 치료한 1예

        박열,박상민,한경택,강지인,이준,김상현 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

        Several studies have shown that patients with rheumatoid arthritis(RA) have a doubled to tripled increased risk for developing lymphomas compared with the general population, Indeed, primary testicular lymphoma accounts for about 1% of all lymphomas. We present a case of RA with primary testicular lymphoma treated with rituximab. A 67-year-o1d man was admitted due to aggravated polyarthralgia and morning stiffness. hIe was diagnosed testicular diffuse large B cell lymphoma (DLBCL) and done orchidectomy last year. There was no adjuvant chemotherapy nor radiotherapy because of patient's loss. Abdominal computed tomography (CT)scan showed about 6x4cm mass on the left adrenal gland. Malignant lymphoma (DLBCL) was proven by CT guided needle biopsy and he was treated with CHOP (cyclophosphamide, hydroxydaunorubicine, oncovin, prednisone) and rituximab (375㎎/㎡) combination regimen. After two cycle treatment, the clinical symptoms and laboratory data improved.

      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • Porocarcinoma Arising in a Ganglion Cyst: A Case Report and Review of the Literature

        Park, Ie Hyon,Kim, Tae Hoon,Kwon, Sung Tack,Park, Ji Ung The Korean Society for Microsurgery 2016 Archives of reconstructive microsurgery Vol.25 No.2

        Eccrine porocarcinoma is a rare malignant neoplasm of the eccrine sweat gland that often occurs in the lower extremities, and usually affects elderly individuals. Most cases of eccrine porocarcinoma arise de novo. We encountered a case of a large porocarcinoma arising in a pre-existing ganglion cyst in the knee. The malignant tumor was excised widely, and the defect was reconstructed using a free anterolateral thigh flap.

      • KCI등재후보

        Korean EFL Learners' Politeness Strategies in Their Complaints

        Park, Ji Hyon 대한언어학회 2001 언어학 Vol.9 No.1

        Park, Jihyon. 2001. Korean EFL Learners' Politeness Strategies in Their Complaints. The Linguistic Association f Korea Journal 9(1), 185-209. In this study, the speech act set of complaint produced by Korean EFL learners was analyzed. Of interest is to see their pragmatic transfer in their complaints from their native language (Korean) to English. The participants in the study are Korean college students enrolled in College English classes at Chonnam National University in Korea. The channel of the communication is electronic mail (e-mail) and the context of the speech act is students complaining about their grades to their instructors. 38 emails written in English and 20 emails in Korean were analyzed with focus on their varying politeness strategies in complaining. The findings suggest that participants performance of speech act reflects their interlanguage pragmatics, which they established in their L2 independent of their Ll. Pedagogical implications and limitations are also discussed. (University of Arizona)

      • Role of STAT3 as a Molecular Adaptor in Cell Growth Signaling: Interaction with Ras and other STAT Proteins

        Song, Ji-Hyon,Park, Hyon-Hee,Park, Hee-Jeong,Han, Mi-Young,Kim, Sung-Hoon,Lee, Choong-Eun Korean Society for Biochemistry and Molecular Biol 2001 Journal of biochemistry and molecular biology Vol.34 No.5

        STATs are proteins with a dual function: signal transducers in the cytoplasm and transcriptional activators in the nucleus. Among the six known major STATs (STAT1-6), STAT3 has been implicated in the widest range of signaling pathways that regulate cell growth and differentiation. As a part of our on-going investigation on the pleiotropic functions of STAT proteins, we examined the role of STAT3 as a molecular adaptor that links diverse cell growth signaling pathways. We observed that STAT3 can be specifically activated by multiple cytokines, such as IL-3, in transformed fibroblasts and IL-4 or IFN-$\gamma$ in primary immune cells, respectively. The selective activation of STAT3 in H-ras-transformed NIH3T3 cells is associated with an increased expression of phosphoserioe STAT3 in these cells, compared to the parental cells. Notably phosphoresine-STAT3 interacts with oncogenic ras, shown by immunoprecipitation and Western blots. The results suggest the role of STAT3 in rasinduced cellular transformation as a molecular adaptor linking the Jak/STAT and Ras/MAPK pathways. In primary immune cells, IL-4 and IFN-$\gamma$ each induced (in addition to the characteristic STAT6 and STAT1 homodimers) the formation of STAT3-containing complexes that bind to GAS probes, which correspond to the $Fe{\varepsilon}$ Rll and $Fe{\gamma}$ RI promoter sequences, respectively. Since IL-4 and IFN-$\gamma$ are known to counter-regulate the expression of these genes, the ability of STAT3 to form heterodimeric complexes with STAT6 or STAT1 implies its role in the fine-tuned control of genes that are regulated by IL-4 and IFN-$\gamma$.

      • KCI우수등재

        가격결정요인분석을 통한 미술품 온라인 경매 특성 연구

        박지현(Ji Hyon Park),신형덕(Hyung Deok Shin) 한국경영학회 2012 經營學硏究 Vol.41 No.4

        As the interests of arts market and the investment increases, the artwork auction market is growing very quickly. The global artwork auction market has grown from $3.6 billion in 2004 to $13 billion in 2010, and so did the domestic artwork auction market. With this expansion, a new area emerged: the online artwork auction market. Since 2006, as the offline artwork auction market grew very quickly, the online artwork auction market also grew quickly. Previous studies have suggested that the online artwork auction would be a reasonable alternative to offline artwork auction market. This study empirically shows if online artwork auctions could be better in mitigating winner`s curse problems than traditional offline artwork auctions in Korea. In this study, we used action fetching price data of 3,108 paintings by Korean artists which have been sold over the period from June 2010 to March 2011 provided by Korean Art Price Appraise Association. We analyzed the impacts of price determinants that were found in previous studies on the fetching price. The price determinants include artists` reputation, material of paintings, and size of paintings. We also controlled artists` survival status, types of objects paintings, and timing of the sales of the paintings. First, artists` reputations have positive and significant influence on both online and offline auction fetching prices. To see the different impacts between online and offline action prices, we conducted t-test and found that the t-value of online auction(t-value= 6.737) was lower than that of offline auction(t-value=16.103). So we confirmed that online auction price is less affected by artist`s reputation than offline auction price is. Second, material of paintings had different impacts on fetching prices of online and offline auctions. We found all positive and significant relationships between types of materials and offline auction fetching prices, but no relationships were found to online prices. Thus, material of paintings does have different impacts on online and offline fetching prices as expected. Third, size of the paintings have significant impacts on both online and offline auction fetching prices. We couldn`t find any difference between size impacts on fetching price of two auctions. Thus, the hypothesis on this was not supported. Next, we investigated if there are differences in the fetching prices compared to the estimate prices between online and offline auctions. We found that the average of online artwork auction fetching prices over estimate prices was 0.724, which was significantly lower than the average of offline fetching/estimate prices of 1.996. This means online bidders buy paintings at far lower price than offline bidders do. We could figure out that the online art auctions have many differences compare to offline art auctions. The difference may come from the fact that online art auctions have more accessibility without space and time limitations than offline ones, and online buyers would be more sensitive to price due to the lack of first-hand looking. The fact that online fetching prices compared to estimate prices are lower that offline cases would imply that online buyers could collect information actively not only from the information that auction company provides but also from other sources. It can be interpreted that online buyers would show more reasonable and rational behaviors than offline buyers. This may imply that online artwork auction market could be a proper alternative to offline artwork auction market where winner`s curse problems exist. Thus, we empirically show and support the rational of the online artwork auction market.

      • KCI등재

        기업지배구조와 기업의 사회적 책임 적합성에 관한 연구

        박지현(Ji Hyon Park),신형덕(Hyung-Deok Shin) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.6

        본 연구는 기업지배구조와 CSR(Corporate Social Responsibility, 기업의 사회적 책임)적합성 간의 관계를 분석한 연구이다. 사회공헌활동의 CSR적합성을 결정하는 요인은 다양함에도 불구하고 아직 그에 관한 연구가 많이 진행되지 않았다. 따라서 본 연구는 기업지배구조가 CSR에 영향을 미치는 주요 요인 중 하나라는 선행연구 결과를 바탕으로 기업지배구조와 CSR적합성 간의 관계에 대해 알아보고자 하였다. 이를 위해 본 연구는 2009년부터 2012년까지의 전국 경제인연합회 사회공헌백서 데이터와 동 기간 한국기업지배구조원이 평가한 기업지배구조 결과를 바탕으로 회귀분석을 진행하였다. 그 결과 기업지배구조와 CSR적합성 사이에는 유의한 부(-)의 관계(β=-.023, p<.05)가 존재한다는 것을 발견하였다. 또한 CSR적합성을 기능, 타겟, 규모적합성 요인으로 나누어 분석한 회귀분석을 통해 기능적합성과 타겟적합성은 기업지배구조와 유의한 부(-)의 관계(β=-.021, p<.05; β=-.016, p<.1)를 가지나 규모적합성은 기업지배구조와 유의한 관계를 갖지 않음을 발견하였다(β=-.005, p=.511). 본 연구는 기업지배구조와 CSR적합성과의 관계에 대해 실증분석하여 그 이유에 대해 새로운 논의의 틀을 제공했다는 점에서 의의를 찾을 수 있다. 또한 CSR적합성의 다양한 유형에 따르는 상이한 의미가 있음을 발견하여 기업에서 CSR적합성을 활용한 전략을 수립할 때 그 목적에 맞는 체계적 접근이 필요하다는 실무적 시사점을 도출하였다. This study has empirically analyzed how far corporate governance and CSR(Corporate Social Responsibility) fit are related based on prior research indicating that corporate governance is one of the primary factors. Previous research suggested that there may be different types of CSR fit, but there have been only limited number of empirical studies. This study filled this gap by categorizing CSR fit into three types (functional fit, target fit, and size fit) and investigating whether different types have different effects. We used data from the Corporate Social Responsibility White Paper for the 2009-2012 period, as well as the Korea Corporate Governance Service (KCGS) index. As a result, we found that there is a negative (-) relationship between corporate governance and CSR fit(β=-.023, p<.05). This can be interpreted that companies with weak corporate governance are attempting to increase the trust level of stakeholders and to reduce the uncertainty of CSR through high-CSR-fitted programs. The test results showed that functional fit and target fit both had negative (-) relationships with corporate governance (β=-.021, p<.05; β=-.016, p<.1), while size fit did not have a significant correlation with corporate governance (β=-.005, p=.511). The results of this study supported the previous studies’ suggestions that CSR fit has different effects on each type, indicating a need for further reflection on the relationship between corporate governance and CSR fit. Also, the results of this study showed that corporations should take a strategic approach to operating CSR fit.

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