췌장 선방세포암 1예

이화정,지준호,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Acinar cell carcinoma is a rare tumor that represents 1~2% of al1 pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-o1d man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased ^(18)F-fluorodeoxyglucose (FDG) uptake Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the Pancreas The patient underwent a total gastrectomy three months later because of gastric recurrence Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabme.

원발성 후복막 점액낭샘암종 1예

지준호,이화정,박승찬,박정철,최은정,서혜진,이원식,이정림,배병조,손경락,이경희 영남대학교 의과대학 2008 Yeungnam University Journal of Medicine Vol.25 No.2

Primary retroperitoneal mucinous cystadenocarcinoma is a very rare malignancy, and little is known concerning its Pathogenesis, optimal treatment, and prognosis. A 29-year-o1d pregnant woman (21 weeks) Presented with abdominal discomfort CA 19-9, CA 125, and CEA were normal Abdominal CT scanning revealed a 19x15x13 cm retropentoneal tumor Exploratory laparotomy and tumor excision were performed. Mucinous retropentoneal implants were removed as completely as possible Histologically, the tumor showed focal areas of capsular invasion, but free resection margins The uterus and both ovaries were normal in appearance No adjuvant therapy was pursued. Six months later, Peritoneal and bilateral ovarian metastases were discovered. Hence, we report the details of this case of primary retroperitoneal mucinous Cystadeno-carcinoma and present a review of the literature.

Genetic associations of body composition, flexibility and injury risk with ACE, ACTN3and COL5A1polymorphisms in Korean ballerinas

( Jun Ho Kim ),( Eun Sun Jung ),( Chul Hyun Kim ),( Hyeon Youn ),( Hwa Rye Kim ) 한국운동영양학회 2014 Physical Activity and Nutrition (Phys Act Nutr) Vol.18 No.2

Jun Ho Kim, Eun Sun Jung, Chul-Hyun Kim, Hyeon Youn and Hwa Rye Kim. Genetic associations of body composition, flexibilityand injury risk with ACE, ACTN3and COL5A1polymorphisms in Korean ballerinas. JENB., Vol. 18, No. 2, pp.205-214, 2014[Purpose] The purpose of this study was to exam the association of body composition, flexibility, and injury risk to genetic polymorphismsincluding ACEID, ACTN3RX, and COL5A1polymorphisms in ballet dancers in Korea. [Methods]For the purpose of this study,elite ballerinas (n = 97) and normal female adults (n = 203) aged 18 to 39 were recruited and these participants were tested forbody weight, height, body fat, fat free mass, flexibility, injury risks on the joints and gene polymorphisms (ACE, ACTN3, COL5A1polymorphism). [Results]As results, the ACEDD genotype in ballerinas was associated with higher body fat and percentageof body fat than the ACEII and ID genotypes (p< 0.05). In the study on the ACTN3polymorphism and ballerinas, the XXgenotype in ballerinas had lower body weight and lower fat-free mass than the RR and RX genotype (p < 0.005). Also, the meansof sit and reach test for flexibility was lower in the ACTN3XX genotype of ballerinas than the RR and RX genotype of ballerinas(p< 0.05). Among the sports injuries, the ankle injury of the XX-genotyped ballerinas was in significantly more prevalence thanthe RR and XX-genotyped ballerinas (p< 0.05). According to the odd ratio analysis, XX-genotyped ballerinas have the injuryrisk on the ankle about 4.7 (95% CI: 1.6~13.4, p< 0.05) times more than the RR and RX-genotyped ballerinas. Meanwhile, theCOL5A1polymorphism in ballerinas has no association with any factors including flexibility and injury risks. [Conclusion]Inconclusion, ACEpolymorphism and ACTN3polymorphism were associated with ballerinas` performance capacity; COL5A1wasnot associated with any factors of performance of Ballerinas. The results suggested that the ACEDD genotype is associated withhigh body fat, the ACTN3XX genotype is associated with low fat-free mass, low flexibility, and higher risk of ankle-joint injury. [Keyword]ballet, flexibility, body composition, injury risk, ACE, ACTN3, COL5A1

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

적응관측기를 이용한 SPMSM의 속도 및 위치 센서리스 제어

정택기,이정철,이홍균,정동화 국립7개대학공동논문집간행위원회 2003 공업기술연구 Vol.3 No.-

This paper is proposed to position and speed control of a surface permanent magnet synchronous motor(SPMSM) drive without mechanical sensor. An adaptive state observer is used for the mechanical state estimation of the motor. The observer is developed based on a nonlinear model of the SPMSM, that employs a d-q rotating reference frame attached to the rotor. A adaptive observer is implemented to compute the speed and position feedback signal. The validity of the proposed sensorless scheme is confirmed by various response characteristics.

HAI를 이용한 IPMSM의 속도 추정 및 제어

정동화,이정철,이홍균 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

This paper presents hybrid artificial intelligent(HAI) controller based on the vector controlled IPMSM drive system. And it is based on artificial technologies that adaptive neural network fuzzy(A-NNF) is to speed control and artificial neural network(ANN) is to speed estimation. The salient feature of this technique is the HAI controller. The hybrid action tolerates any inaccuracies in the fuzzy logic assignment rules or in the neural network stationary weights. Speed estimators using feedforward multilayer and artificial neural network(ANN) are compared. The back-propagation algorithm is easy to derived the estimated speed tracks precisely the actual motor speed. This paper presents the theoretical analysis as well as the simulation results to verify the effectiveness of the new hybrid intelligent control

석탄회 및 석고첨가가 퇴비화에 미치는 영향

유현철,김정섭,곽명화,윤철종,이희인,박승조 동아대학교 환경문제연구소 2001 硏究報告 Vol.24 No.1

Problems of wastes that pigs produce are increasing rapidly in the hog raising industry nowadays. consequently, the generation volume of excreta also is increasing but most of that is not disposed appropriately and exposed in eco-system therefore the disposal of stock excreta is becoming more and more serious. considering the physical and chemical characteristics of livestock excreta, the pollution loading rate - BOD, COD etc. - is very high. as alternative plan, that is, as one method kind of composisting, the utilization of the soil reformation agent will become one solution in managing the upper problems. also, the flyash of 3.7 million tons are producing every year and about 32.2% of that, 1.18 million ton is recycled as concrete, cement, cementassistance, road etc. consequently, the discharged flyash is not abandoned and a plan of recycling is needed acutely. gypsum of 4.16 million tons in 1998 presently was produced and about 57.2% of that, 2.38 million tons was recycled as cement, construction materials. the present stock is 25 million tons. therefore, in this study, because organic materials can be obtained in pig excreta and calciums can be obtained in gypsum, the small amount of elements can be acquired in flyash for the soil reformation agents, mixing the three materials - pig excreta, gypsum, flyash - adequately, investigated technique of making the soil reformation agents and described below in comparrision with the changes of temperature, PH TOC, T-N, TOC/T-N ratio etc.

화학기상증착 반응기 시뮬레이션 연구

서화일,장호정,장영철,석창길,이은호,임장규 호서대학교반도체제조장비국산화 연구센터 2000 반도체 장비기술 논문집 Vol.2000 No.-

컨버터로 제어되는 유도전동기 드라이브 시스템의 손실 모델링

정동화,이정철,박기태,이홍균 순천대학교 1999 순천대학교 자연과학논문집 Vol.18 No.2

An accurate loss model of induction motor drive controlled by the converter is proposed. Steady state fundamental and hamonics loss characteristics, besides the dynamics of the machine are analyzed and incorporated in the model, resulting in a new synchronous frame dynamics d-q equivalent circuit. The converter system has been modeled accurately for condition and switching losses.

약계자 영역에서 SynRM의 최대 토크제어를 위한 센서리스 벡터제어

이정철,정동화 한국산업안전학회 2002 한국안전학회지 Vol.17 No.2

In this paper, a new approach for the SynRM(Synchronous Reluctance Motor) control which ensures producing MTPA(Maximum Torque per Ampere) over the entire field weakening region is presented. In addition, this paper presents a speed sensorless control scheme of SynRM using flux observer. Also, by adjusting the base speed for the field weakening operation according to the flux level, the current and voltage limit, the smooth and precise transition into the field weakening operation can be achieved. The validity of the proposed scheme is verified through simulation.