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나병곤,배학연,조현진,김권천 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.3
Purpose: Papillary thyroid microcarcinoma (PTMC) is increasing in incidence because of ultrasound-guided fine-needle aspiration cyology (FNA). According to WHO, PTMC is defined as a papillary thyroid cancer of 1 cm or less in diameter. Within the group of patients with PTMC, prognosis is known to be very favorable. This study was carried out to evaluate the clinicohistological characteristics of PTMC and to determine a reasonable extent of surgery for them. Methods: From Mar. 2002 to Dec. 2007, 610 patients with thyroid diseases underwent thyroidectomy at Chosun University hospital. Among these patients, 205 patients (33%) had a thyroid papillary carcinoma less than or equal to 1 cm in great diameter. The clinicopathologic features and treatment outcome of these patients were evaluated retrospectively. Results: In the period 2002-2007, PTMC incidence rate in our institution increased from 10% to 20%. There were 19 men and 186 women with a median age of 46 years (range; 16-74). PTMC diameter ranged from 0.1 to 1 cm. (mean 0.54 cm) 15.7% of patients with PTMC presented with preoperative symptoms (palpable mass, fatigue, pain, hoarseness). Preoperatively 84.3% of these 205 cases were diagnosed by ultrasonography. We performed unilateral lobectomy (41%), near total thyroidectomy (44%), and total thyroidectomy (11%) with or without central compartment neck node dissection. During a mean follow-up of 36 months, 5 patients (2.4%) developed locoregional recurrence with no distant metastasis. There were no significant difference on recurrence rate by size, capsular invasion. But multiplicity of primary tumor has a higher locoregional recurrence rate (p= 0.04). The detection rate of PTMC is increasing due to FNA technique in our hospital. This study shows that PTMC may have capsular invasion, lymph node involvement, multiplicity and locoregional recurrence likely to larger (>1 cm) papillary carcinoma. Conclusion: We suggest that total or near total thyroidectomy with central compartment neck dissection is proper therapeutic operation for PTMC and modified neck dissection shoud be performed if lateral neck lymph node are enlarged or diagnosed as metastatic tumor.
이상형 스테인레스강의 크롬질화물 석출과 상 방위관계 연구
최병학,김진우,고석민,조용석,김상식,이재현 국립7개대학공동논문집간행위원회 2002 공업기술연구 Vol.2 No.-
Microstructures in the directionally solidified duplex stainless steels were investigated in order to understand the effect of nitrogen addition and its precipitation in the α phase. It was found that the addition of nitrogen causes the formation of fine precipitates in α matrix and segregation phases of nitrogen in the α/γ interface. Both the fine precipitates and the segregation phases were identified as CrN(fcc, a=4.18Å), as a coherent phase related to the α-bcc matrix with crystal relationship of (200) CrN//(01 ̄1)α and (1 ̄1 ̄1)CrN//(3 ̄2 ̄1)α.
船舶용 알루미늄合金材의 腐蝕疲勞龜裂 傳播特性에 미치는 腐蝕傳立의 影響
朴炳學,李鐘樂,曺義一,林祐助 여수대학교 1990 論文集 Vol.4 No.-
Recently, with the tendency of more lightening, high-strength and high-speed in the marine industries such as marine structures, ships and chemical plants, it is rapidly enlarged the use of AL-Alloy and there occurs much interest in the study of corrosion fatigue crack characteristics. Those ships were encountered the corrosion fatigue fracture because of the repeated stress by ship vibration and wave on the voyage under the marine environmentes. In this paper, the occurance of corrosion fatigue crack and the propagation behavior of the 5086-H112 Al-Alloy was tetsted by use of a rotary bending tester and was investigated, on condition of changing corrosion potential (-540, -762, -781 and -794mv/SCE) and air. The experimental constants of Paris'rule was examined in the various corrosion potential, and the enfluence of load and corrosion affected with the crack growth rate was compared with. The retardation effect of corrosion fatigue crack propagation in E=-794mv(SCE) was quantitatively studied.
민병무,김용백,박근성,송규상,양준묵,이성복,조항진,길숙종,김승영,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
An improved retinal tack can be used to fix the retina in complicated retinal detachment and proliferative vitreoretinopathy. We used the retinal tack made by biodegradable polyglycolic acid, polylactic acid and copolymers. The tacks with polyglycolic acid were placed in the retina the right eyes of 10 rabbits as group 1, with polylactic-polyglycolic acid copolymers as group 2 in each left eyes. We examined the absorption rates and degree of intraocular inflammation at 1 day, 1, 2, 4, and 8 weeks and compared both eyes. The tacks were absorbed with time in both eyes, but more rapid in copolymers. And there was no inflammation in both eyes. Now, this study will be a base on the drug delivery system in intraocular pharmacological and surgical management.
공급체인 관리 관점에서 대량 고객 맞춤화의 핵심성공요인 도출에 대한 연구 : ANP 접근법을 기반으로 ANP-based Approach
임병학,조호현 釜山外國語大學校 2005 外大論叢 Vol.31 No.-
본 연구는 분석적 네트웍 프로세스을 이용하여 공급체인 관리 관점에서 대량 고객 맞춤화의 핵심성공요인을 도출하는 구조적 프레임웍을 제안했다. 본 프레임웍은 크게 네 단계로 구성되어 있다. 첫째 단계는 공급체인관리의 전략 유형 도출이다. 둘째 단계는 대량 고객 맞춤화 전략 유형 도출이며, 세째 단계는 대량 고객 맞춤화의 성공요인 및 촉진자의 도출이다. 네째단계는 위단계에서 도출된 특성에 의한 분석적 네트웍 계층 모형의 설계 및 그 모형을 기반으로 대량 고객 맞춤화의 핵심 성공 요인을 결정하는 것이다. 본 연구는 공급체인 전략과 대량 고객 맞춤화 전략간 관계를 고려한 핵심 성공요인 도출을 좀더 현실적으로 과학적인 핵심 성공요인을 도출하여 핵심 요인의 전략적 관리를 할 수 있도록 했다는데 의의가 있다. This paper provides a structural framework of determining critical success factors for mass customization in supply chain management perspective. This framework consists of four steps. First of all, types of suppy chain strategies are derived, and then the second step is to determine the types of mass customizations. Third step is to design and analyze determinants and enablers for mass customization. Final step is to design an analytic network hierarchy model and to then determine critical success factors for mass customization. This study is to consider the relationship between supply chain strategies and mass customization strategies and determine the more realistic and scientific critical success factors on the relationship.
생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구
민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.
위암환자의 복강내에 투여한 Mitomycin C-Carbon Particle의 Mitomycin 용출에 관한 연구
노승무,조영훈,정경수,오정연,김진향,양준묵,강대영,송규상,조준식,최선웅,이진호,민병무,김용백,김창식,박근성,인현빈,정현용,김학용 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1
Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherpy seems a logical choice for cancer chemotherapy. The Mitomycin C(MMC) adsorbed by the activated charcoal particles(CH) is relatively released when the drug concentration surrounding the carbon particles becomes low in the peritoneum of the peritoneal cavity. For the intraperitoneal chemotherapy on the advanced gastric adenocarcnoma, mitomycin C adsorbed on activated carbon particles was administered in the peritoneal cavity just before abdominal wall closure. The closed drainage tubes were inserted in the peritoneal cavity and clamped for tuo hours after completion of operation. MMC concentrations were serially measured in peritoneal fluid, plasma and urine at 2hour, 48 hour, 72 hour and 168 hour following its administration in order to study the efficacy of the MMC-CH as a drug delivery system. There were minimal toxicities in born marrow, liver, and gastrointestinal system after intraperitoneal MMC-CH administration. The data of this study suggested that MMC-CH may have a somewhat more beneficial effect than surgery alone when administered in optimal dose and schedules, but the MMC concentration of the peritoneal fluid was not sufficient to eradicate remnant cancer cells, and effective duration of maintenance was only below 24 hours in the peritoneal fluid and plasma.
20주간의 혼합운동프로그램이 정신지체 성인의 신체조성과 체력에 미치는 효과
전종귀,염동삼,조병준,이상기,박희근,한동수,장학영 한국특수체육학회 2004 한국특수체육학회지 Vol.12 No.3
The purpose of this study was to figure out the effects of participation in a combined exercise program on the body composition and physical fitness of adults with mental retardation. Fifteen adults with mental retardation in a special institute took part in aerobic and strength , combined exercise at 55 - 69%HRmax at least one hour a day, 3 times a week for 20 weeks. The body composition and physical fitness profiles of subjects were measured before and after training period, respectively. Dependent t-test was used to analyze the statistical significance. The results were as follows; First, participants showed more favorable % body fat, lean body mass, fat mass, WHR after training. Second, participants showed more improved upper body strength and balance after training. The findings imply that the combined exercise program for long duration had significant effects on the health promotion of adults with mental retardation.