노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성

유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

CD34+ 조혈 모세포 이식 2례

김정아,정현식,김원석,윤성수,이홍기,박찬형,박성규,김동욱,이종욱,한치화,민우성,김춘추,김동집 대한조혈모세포이식학회 1996 대한조혈모세포이식학회지 Vol.1 No.1

Background: In most solid tumors, the CD34 antigen has not been detected, so positive selection of CD34+ cells may reduce tumor cell contamination and the CD34+ cells are capable of reconstituting hematopoiesis. We tried CD34+ cell transplantation in two patients. Method: CD34+ cells from chemotherapy + G-CSF mobilized PBPCs or bone marrow were positively selected with an avidin-biotin immunoadsorption column (CEPRATE SC system). Case 1. One course of chemotherapy using cyclophosphamide(200㎎/㎡) and etoposide (4.2g/㎡), combined with G-CSF(5㎍/㎏) S.C. was used in a relapsed lymphoma patient. This patient responded to the induction chemotherapy. CD34+ cells from harvested bone marrow were selected by the CellPro immunoadsorption column. The total number of mononuclear cells loaded onto the CellPro was 2.4×10^(8)/㎏, with 1.1% CD34+ cells. After column separation, the total number of positively selected cells was 5.16×10^(6)/㎏. The number of CFU-GM was 76.8×10⁴/㎏. This patient was treated with melphalan (140㎎/㎡) and TBI (1200cGy) and the positively selected CD34+ cells were infused. The time to neutrophil recovery greater than 0.5×10^(9)/L was 19 days and the time to platelet recovery greater than 50×10^(9)/L was 21 days. Case 2. Two courses of mobilizing chemotherapy were given 4 weeks apart using taxol(210㎎/m2) and adriamycin(60㎎/m2), combined with G-CSF(5㎍/㎏) S.C. in a breast cancer patients with 7 axillary node metastasis. CD34+ cells from each single leukapheresis product were selected by the CellPro immunoadsorption column. In the first collection, the total number of nucleated cells was 4.4×10^(8)/kg, with 0.42% CD34+ cells. In the second collection, the total number of nucleated cell was 2.8× 10^(8)/㎏ with 0.43% CD34+ cells. After colum separation, the total numbers of collected cells were 4.0×106/kg and 4.8×10^(6)/kg, the total number of CD34+ cells were 1.2×10^(6)/㎏ and 0.82×10^(6)/㎏. Colonogenic assays of positively selected CD34+ cells gave rise to myeloid erythroid, and multilineage colonies, with a median of 190 CFU-GM, 190 BFU-E, and 164 CFU-GEMM per 1×10³ adsorbed cells, respectively. High-dose chemotherapy with cumulative doses of 40mg/㎡ mitoxantrone, 750mg/㎡ thioptepa, and 1000mg/㎡ carboplatin was administered. Positively selected CD34+ cells were rapidly infused 24 hours after the end of high-dose chemotherapy. The time to neutrophil recovery greater than 0.5×10^(9)/L was 16 days and the time to platelet recovery greater than 50×10^(9)/L was 20 days.

미드의 白我理論과 社會科敎育

韓相旭 순천대학교 사회과학연구소 1989 社會科學硏究 Vol.2 No.-

The goal of social studies is to develop the democratic citizenship of the students. And that democratic citizenship means the self of the person in a democracy. So, the goal of social studies is to make students take the role of the generatized other. According to Mead, the self arises from the social organization to which it belongs, while the social organization reflects the self. The self is not initially there, at birth, but arises in the process of social experience and activity, that is, develops in the given individual as a result of his relations to that process as a whole and to other individuals within that process. A person is a personality because he belongs to a community, because he takes over the institutions of that community into his own conduct. He takes its language as a medium by which he gets his personality, and then through a process of taking the different roles that all the others furnish he comes to get the attitude of the members of the community. He continually takes the attitudes of the others about him, especially the roles of those who in some sense control him and on whom he depends. Such Mead's Theory of self implies very important points to the social studies education. First, the teacher should make the students know that he really expects the students to be democratic and moral beings, because the students take the attitude of the teacher on whom they depend. Second, the students should continually be asked to put themselves in the place of the generalized other, because the only way to learn to take the attitude of the other is to engage in taking that of the other. Only this approach in social studies education will affect the citizenship and the self of the students.

근관장 측정시 구내 디지털 방사선 시스템인 Digora System의 정확도에 관한 연구

한상욱,홍찬의,조용범 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.1

이중관 기포탑에서의 비뉴튼류의 기-액간 물질이동

한승환,김상렬,최재욱,최일곤 東亞大學校 1991 東亞論叢 Vol.28 No.1

The effect of draught tube dimension, properties of CMC aqueous solution and gas velocity on the gas holdup, ??, and the volumetric liquidphase masstransfer coefficient, ??, in a bubble column with draught tube were measured in highly viscous-pseudo plastic carboxymethylcellulose aqueous solution. The results were as follows : 1. ?? and ?? increase with increasing gas velocity and decrease with increasing concentration of CMC aqueous solution. 2. ?? and ?? increase with being enlarged diameter ratio of draught tube but specially ?? decreases to some degree in the CMC concentration of 0.05∼0.7wt%. 3. Correlations among various parameters having an influence on ?? and ?? were expressed by Eq. (16) and Eq. (17), respectively. ??

Dioxin류의 반응에 대한 분자궤도함수론적 연구 : dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran, 2,8-dichlorodibenzofuran 중심으로

한성욱,이길준,김복조 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(B)

Molecular orbital studies for dibenzo-p-dioxin, 2,7-dichlorodibenzo-p-dioxin, dibenzofuran and 2,8-dichlorodibenzofuran were carried out by semiempirical PM3 method. Reaction sites for nucleophilic, electrophilic and radical reaction of dioxins were predicted and discussed by MO studies. The values of approximated superdelocalizability were 0.7802, 0.2686, 0.3104, 0.1982 for the above dioxins, respectively. And reported rate constant for the reaction of dioxins with OH radical (Eitzer et. al.. Environ, Sci. Technol. 1989, 23, 1389) was well correlated with approximated superdelocalizability.

유기리간드를 포함하는 팔라듐(Ⅱ), 니켈(Ⅱ), 착물의 trans-영향 및 안정성

한성욱,정맹준 경운대학교 산업기술연구소 1998 産業技術硏究論文誌 Vol.1 No.1(A)

The trans-influence and stability of the Pb(L)Cl₂ and Ni(L)X₂(X=Cl, Br, I) wherein L is 1,2-bis{(diphenylphosphino)amino}ethane were studied by spectroscopic methods. The complexes were prepared and characterized by elemental analysis, IR, UV, ¹H, and ^31P NMR spectroscopy. The [Ni(L)I₂] is tetrahedral, where [Pb(L)Cl₂] and [Ni(L)X₂](X=Cl, Br) are square planar. From the IR and δ^31P(ppm) data, it is appeared that the M-Cl bond strength were different inorder to metal(Ⅱ) ion in the [M(L)Cl₂] (M=Pb, Ni) system and the M-P bond strength were different inorder to halogen atom in the [Ni(L)X₂](X=Cl, Br, I) system. The complexes, [Ni(L)X₂](X=Cl, Br) become tetrahedral as they react with methyl iodide.

효율적인 현장체험학습을 위한 암남공원의 지질에 관한 연구

한영욱,김상권,유병태 부산교육대학교 과학교육연구소 2004 科學敎育硏究 Vol.29 No.-

The purpose of this study is to find out the study of the effective field experience learning method through the geological survey of the Amnam Park. The field experience learning has been used in the general subjects and in that case data supply is common. But the data supply is lack in the programs of the earth science especially in Busan , it is rare to learn geological matters with topography of Busan. With the results of this study it is possible to maximize the learning effect by using the outdoor environments. The Amnam Park which is accessible to students with convenient transportations has the effective stratum outcrops for the different rocks, faults, folds, intrusion of magma, metamorphic-contact transformation rocks what show the various lithosphere change phenomenon and the lithosphere leveling. With the results of the concentrative survey of the Amnam Park, this study proposes the localization of the text of the local environment of nature, application and shows the way of the teaching and learning effects. As the results are as follows. First the Amnam Park specifies the geological history of Busan observing the stratum outcrops of that place which was consist of terrestrial deposit(accumulative layer) in the Lake or swamp environments. Second the Amnam Park shows the topographical characteristics formed by the lithosphere leveling and the movement of seawater and various topographical facts for example weathering, erosions, coast terrace, erosion by seawater caves. Third the Park has the variety of the stratum outcrops and evidences of lithosphere transformation relatively in the Small space. It has the advantage for the worthy geological learning place owing to accessible location. Using the field experience learning relating the geological unit in the Elementary School has effective learning for the students. The field experience learning with the text of localization provides the students with the love for their own place and the spirit for the preservation of nature as the accessory effects.

가금티푸스 저항성 계통 선발을 위한 산란종계의 경제능력 검정에 관한 연구

한성욱,이봉덕,전익수 충남대학교 농업과학연구소 2001 농업과학연구 Vol.28 No.2

가금티푸스에 저항성을 가진 합성종을 생산하기 위하여 갈색계통인 이사(ISA), 하이라인(Hyline), 로만(Lohman) 3 계통과, 백색계통인 인사 (ISA) 및 로만(Lohman) 2 계통의 종계(PS)에 대한 생존율, 사료섭취량, 체중, 성성숙일령, 시산 난중, 및 난질을 조사하였다. 성계 암컷 생존율(34주∼66주)은 갈색계통과 백색계통에서 각각 93.3%, 93.5%로 차이가 없었고, 수컷 생존율에도 차이가 없었다(P>0.05). 수당사료 섭취량(21∼66주)은 암컷에서 갈색계통과 백색계통이 각각 113.9g과 114.3g으로 비슷한 수준이었으며, 수컷에서도 차이가 없었다. 성계 체중은 암·수 공히 갈색 산란종계 3계통 및 백색 산란종계 2계통간에 유의한 차이가 없었다. 갈색과 백색 산란종계의 체중을 비교해 보면, 갈색 산란종계가 암컷과 수컷 모두 백색 산란종계 에 비하여 무거웠으나, 반복간에 변이가 워낙 커서 유의성은 검출되지 않았다. 성성숙일령은 갈색계통과 백색계통이 각각 147.8일과 140.5일로 갈색계통이 7일정도 늦었다(P<0.05). 산란율은 23-66주에서 갈색과 백색계통이 각각 75.0% 및 81.4%로 백색계통이 약 6% 높았다(P<0.05). 39주령에 갈색란과 백색란의 난질 성적을 비교해보면 Haugh Unit, 난형계수, 난황색, 난중에 있어서는 유의한 차이가 검출되지 않았다. 그러나 난각두께는 갈색 산란계통의 계란이 더 두꺼웠고, 난각강도도 유의하게 강한 것으로 나타났다. A preliminary experiment was conducted to produce fowl-typhoid resistant egg type breeds, using three brown egg layer breeders (ISA, Hyline, and Lohman) and two white egg layer breeders (ISA and Lohman). Various economic parameters were measured from day-old to mature stages using parent stocks of each breed. No significant difference in viabilities of mature hens from 34 to 66 wk of ages was found between brown(93.3%) and white(93.5%) egg layer breeders (P>0.05). Also, there was no difference in viabilities of mature cockerels. Although not significant the mature body weights of brown egg layer breeders tended to be heavier than those of the white egg layer breeders both in hens and cockerels. No difference in feed intakes of mature brown and white hens were detected. Ages of sexual maturity of white and brown egg layer hens were 147.7 and 140.5 d, respectively (P<0.05). Egg production of white egg layer hens during 23-66 weeks age was significantly higher than their counterpart (81.4% vs. 75.0%). Comparisons of Haugh Unit, egg shape index, yolk color, and egg weight between brown and white eggs were not significantly different, however, the brown eggshells were thicker and stronger than those of white eggs (P<0.05).