Celay/In-Ceram, Conventional In-Ceram, Empress 2 전부도재관의 변연적합도에 관한 비교 연구

양재호,여인성,이선형,한중석,이재봉,Yang, Jae-Ho,Yeo, In-Sung,Lee, Sun-Hyung,Han, Jung-Suk,Lee, Jai-Bong 대한치과보철학회 2002 대한치과보철학회지 Vol.40 No.2

There have been many studies about marginal discrepancy of single restorations made by various systems and materials. But many of statistical inferences are not definite because of sample size, measurement number, measuring instruments. etc. The purpose of this study was to compare the marginal adaptations of the anterior single restorations made by different systems and to consider more desirable statistical methods in analysing the marginal fit. The in vitro marginal discrepancies of three different all-ceramic crown systems (Celay In-Ceram. Conventional In-Ceram. IPS Empress 2 layering technique) and one control group (PFM) were evaluated and compared. The crowns were made from one extracted maxillary central incisor prepared with a 1mm shoulder margin and $6^{\circ}$ taper walls by milling machine. 10 crowns per each system were fabricated. Measurements or a crown were recorded at 50 points that were randomly selected for marginal gap evaluation. Non-parametric statistical analysis was performed for the results. Within the limits of this study, the following conclusions were drawn: 1 Mean gap dimensions and standard deviations at the marginal opening for the maxillary incisor crowns were $98.2{\pm}40.6{\mu}m$ for PFM, $83.5{\pm}18.7{\mu}m$ for Celay In-Ceram, $104.9{\pm}44.1{\mu}m$ for conventional In-Ceram, and $45.5{\pm}11.5{\mu}m$ for IPS Empress 2 layering technique. The IPS Empress 2 system showed the smallest marginal gap (P<0.05). The marginal openings of the other three groups were not significantly different (P<0.05). 2 The marginal discrepancies found in this study were all within clinically acceptable standards ($100\sim150{\mu}m$). 3. When the variable is so controlled that the system may be the only one, mean value is interpreted to be the marginal discrepancy of a restoration which is made by each system and standard deviation is to be technique-sensitivity of each one. 4. From the standard deviations. the copy-milling technique (Celay/In-Ceram) was not considered to be technique-sensitive in comparison with other methods. 5. Parametric analysis is more reliable than non-parametric one in interpretation of the mean and standard deviation. The sample size of each group has to be more than 30 to use parametric statistics. The level of clinically acceptable marginal fit has not been established. Further studies are needed.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

자성선숙어(protogynous fish)의 성전환

이정재,김형배,박인석,고환봉,이영돈 濟州大學校海洋硏究所 1993 해양과환경연구소 연구논문집 Vol.17 No.-

제주 연근해에 서식하는 자성선숙형 자웅동체어인 놀래기류와 능성이류를 대상으로 성전환에 따른 생식소의 조직학적 변화와 체색의 변화 등의 성적이형 현상을 토대로 하여 성전환 특성을 고찰하였다. 1. 용치놀래기, 어렝놀래기, 놀래기는 6월과 7월에 주산란을 하는 하계산란종인 반면에 황놀래기는 10월과 11월에 산란하는 추계산란종이였다. 2. 성전환 체장범위는 용치놀리기 13. 0-15. 0㎝, 황놀래기는 11.5-16.0㎝, 그리고 놀래기 전장 10.0-13.0㎝였다. 3. 성전환은 주로 산란기 전후로 하여 나타나고 있다. 용치놀래기, 어렝놀래기, 놀래기는 1차웅과 2차웅이 혼재하고 잇으나 어렝놀래기는 2차웅만이 출현하였다. 4. 성전환에 따른 용치놀래기, 어렝놀래기, 황놀래기 체색변화는 선홍색 또는 선황색 계통에서 색조가 다양한 녹색이나 황색계통으로 전환되고 있다. 놀래기의 경우 전반적의 체색의 변화는 미미하나 몸 가운데에 파란반점과 가로줄무늬를 띠고 있다. 어렝놀래기 경우 체색의 변화와 함께 등지느러미 제1, 2극의 돌기가 신장되고 있다. 5. 성전환 과정에 따른 놀래기류의 생식소내 조직학적 변화는 난모세포의 퇴행변성에 따라 다양한 간질세포와 혈관의 발달을 보였다. 이후 난소의 박판주위에서 정원세포와 정모세포들이 출현하기 시작하여 기능적 정소로 전환되고 있다. 6. 자바리는 전장 30.0-92.3㎝, 능성어는 전장 23.4-38.7㎝에서 생식소내 주변인기 난모세포를 갖는 암컷이었고, 붉바리는 전장 22.0-33.0㎝에서 양성생식소를 갖는 개들도이 출현하고 있다. Studies and reviews have been based on sex reversal diagnosis of histological change and body color change by sexual dimorphism on protogynous hermaphrodite fish, Labridae, Serranidae inhabited at the costal area of Cheju-do, Korea. Halichoreres poealopterus, Pteragogus flagellifera and H, tenuispinis were summer season, spawing species which mainly spawn in Jun and July, but Pseudolabrus japonicus was autumn season spawing species which mainly spawn in October and November. The standard length range of sex reversal were 13. 0-15. 0㎝ H, poecuilopterus, 9. 5-15.0㎝ P,flagellifer, 11. 5-16 0㎝ P, japonicus, and 10. 0-13 0㎝ (total length) H, tenuispinis respectively. Sex reversal mainly appeared before and after spawing season. H. Poecilopterus, H. tenuispinis and P. japonicus were composed of monandry and diantry, but P. flagellifera was diandry. By sex reversal, the body colors of Ho poecilopterus, P. flagellifera and P. japonicus change from pale red or yellow lines to brilliant green or dark yellow lines. The body colors of H. tenuispinis change slight, but containe lateral stripe pattern and blue spot in body center. In P.flagellifera, 1st, 2nd spine process of dosal fin were grown with body colour change. In sex reversal process, histological change of Labridae of inner gonad showed development of various interstitial cells and blood vessel by degeneration of oocyte. Thereafter, spermatogonia and spermatocyte begin to appear at the inner edge regions of the ovarian lamellae and then converted from ovary to functional testis. Epinephelus moara of 30. 0-92.3㎝ in TL, E.Septenfasciatus of 23. 4-38.7㎝ in TL were female with contained oocyte of perinucleolus stage. E. akaara of 22.0-33.0㎝ in TL appeared individuals of ovotestis.

자성선숙어(protogynous fish)의 성전환

이영돈,고환봉,김형배,박인석,이정재 제주대학교 해양연구소 1993 해양자원연구소연구보고 Vol.17 No.-

Studies and reviews have been based on sex reversal diagnosis of histological change and body color change by sexual dimorphism on protogynous hermaphrodite fish, Labridae, Serranidae inhabited at the costal area of Chejudo. Korea Halichorens poecilopterus, Pleragoguw flagellifera and H. teruispinis were summer season, spawing species which mainly spawn in Jun and July, but Pseudolobrus japonicus was autumn season spawing species which mainly spawn in October and November, The standard length range of sex reversal were 13.0-15.0cm H. poecilopterus 9.5-15.0cm P. flagellifer, 11.5-16.0 cm P. japonicus and 10.0-13.0cm (total length) H. teraispinis respectively. Sex reversal mainly appeared before and after spawing season. H. Poecilogterus, H. terusispirus and P. japonicus were composed of monandry and diantry, but P.flagellifera was diandry. By sex reversal, the body colors of H. poecilopterus, P.flagellifera and P. japoricus change from pale red or yellow lines to brilliant green or dark yellow lines. The body colors of H. tenurisspirnis change slight, but containe lateral stripe pattern and blue spot in body center. In P. flagellifera, 1st, 2nd spine process of dosal fin were grown with body colour change. In sex reversal process, histological change of Labridae of inner gonad showed development of various interstitial cells and blood vessel by degeneration of oocyte. Thereafter, spermatogonia and spermatocyte begin to appear at the inner edge regions of the ovarian lamellae and then converted from ovary to functional testis. Epinephelus moara of 30.0~92.3cm in TL, E. Septemfasciatus of 23.4~38.7cm in TL were female with contained oocyte of perinucleolus stage. E akaara of 22.0~33.0cm in TL appeared individuals of ovotestis.

용접공들의 면역능에 관한 연구

이수일,조봉수,김영욱,고광욱,조원근,김영실,강수용,황인경,조병만,김돈균 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.1

The authors examined human immunity indicators such as CD4, CD8, Natural Killer(NK) cell, IgG, IgA, and IgM, and heavy metals such as Pb, Cr, Cd to evaluate the health hazard of welders. We selected total 126 male subjects, 60 welders who had more than 5 year working history as an exposure group, and 66 office workers and medical college students as a control group. This immunity evaluation approach is the first newly designed study that has never been tried in past studies on welder's heath evaluation. And the results were as follows. 1. Total lymphocyte count of peripheral blood was significantly higher in welder group, 2,615±650 ea/㎕ compared with 2,368±681 ea/㎕ in control group(p>0.05). 2. The proportion of CD4, CD8, NK cell in welder group was 37.5±9.4%, 24.0±8.8%, and 21.0±9.5%, respectively, and 35.5±6.5%, 25.0±6.9%, and 19.6±8.8% in control group. CD4 and NK cell were slightly higher, and CD8 was slightly lower in welder group. but there was no statistical significance between two groups(p≥0.05). 3. IgG, IgA, and IgM in welder group were 15.9㎎/㎗, 2.7㎎/㎗ and 1.5㎎/㎗, respectively, and 15.6㎎/㎗, 2.9㎎/㎗ and 1.7㎎/㎗ in control group. There was no statistical significance between two groups(p≥0.05). 4. Blood lead, cadmium and chromium concentrations were 4.2±1.8㎍/㎗, 0.4±0.38㎍/㎗, 1.2±0.6㎍/㎗ in welder group and 3.2±1.7㎍/㎗, 0.44±0.29㎍/㎗, 1.1±0.6㎍/㎗ in control group, respectively, and these value were within normal ranges.

In-vitro and in-vivo anti-inflammatory and antinociceptive effects of the methanol extract of the roots of Morinda officinalis

Kim, In-Tae,Park, Hee-Juhn,Nam, Jung-Hwan,Park, Young-Mi,Won, Jong-Heon,Choi, Jong-Won,Choe, Bong-Keun,Lee, Kyung-Tae EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The anti-inflammatory effects of the methanol extract of the roots of Morinda officinalis (MEMO) (Rubiaceae) were evaluated in-vitro and in-vivo. The effects of MEMO on lipopolysaccharide (LPS)induced responses in the murine macrophage cell line RAW 264.7 were examined. MEMO potently inhibited the production of nitric oxide (NO), prostaglandin E₂and tumour necrosis factor-α (TNF-α) in LPS-stimulated RAW 264.7 macrophages. Consistent with these results, the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) at the protein level, and of iNOS, COX-2 and TNF-α at the mRNA level, was also inhibited by MEMO in a concentration-dependent manner. Furthermore, MEMO inhibited the nuclear factor kappa B (NF-κB) activation induced by LPS, and this was associated with the prevention of degradation of the inhibitor κB (IκB), and subsequently with attenuated p65 protein in the nucleus. The anti-inflammatory effect of MEMO was examined in rats using the carrageenan-induced oedema model. The antinociceptive effects of MEMO were assessed in mice using the acetic acid-induced abdominal constriction test and the hot-plate test. MEMO (100, 200㎎㎏^(-1) per day, p.o.) exhibited anti-inflammatory and antinociceptive effects in these animal models. Taken together, the data demonstrate that MEMO has anti-inflammatory and antinociceptive activity, inhibiting iNOS, COX-2 and TNF-α expression by down-regulating NF-κB binding activity.

골퍼의 기능수준에 따른 운동상해요인 비교 분석

이석인,박봉섭,김재훈 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

The purpose of this study is to provide professional and amateur golfers with the basic guide to prevent injuries when playing golf. In order for that, the researcher has first researched the individual background of golfers and the parts, forms, and causes of injuries that they have according to their level of function. And also the researcher has taken a survey from professional and amateur golfers living in Seoul, Kyung-gi, and In-cheon in 2003. In order to compare and analyse these information gathered from each golfers about the injuries, questionnaires have been arranged on the basis of the studies of Batt(1992), Lee(1996), Roh(1996), Lee(1997), and Park(1998), Lee(2002). The appropriateness and validity of the contents of these questionnaires were verified after taking a preliminary test choosing each 20 of the professional and amateur golfers. Therefore, this source of questionnaires is believable with its high reliability. The statistic method in this study is frequency Analysis and x test. The results are as the followings. Injuries occur more to professional golfers than amateur golfers. And also they often have the skin injury and muscular injury because of the pressure they get to win the game doing over-exercise.

남부 평야지 자운영재배답에서 논유형과 질소수준이 벼 생육 및 토양 화학성에 미치는 영향

윤봉기,김병호,이인,최형국,박인진,김용웅 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.3

녹비작물로서 자운영을 재배한 논에 벼를 재배할 때 질소비료의 절감기준을 구명하고자 평야지인 전남 나주의 보통답과 사질답에서 관행, 자운영+질소 70%, 자운영+질소 50%, 자운영+질소 30%, 자운영+무질소의 5처리로 1999년부터 2001년까지 3년동안 시험한 결과는 다음과 같다. 1. 자운영의 개화성기 생육은 초장 43.6~43.9㎝, 생초중 21.79~24.99Mg ha^(-1)이였으며 무기성분 함량은 T-N 2.40~2.64%, P₂O_(5) 0.42~0.46%, K₂O 1.83~2.01%였다. 자운영의 생육은 보통답이 사질답에 비하여 생초중이 많았고 T-N, T-C, P₂O_(5), CaO, MgO의 함량도 높았다. 2. 토양중 NH₄-N함량의 경시적 변화는 이앙후 7일에 20.7~47.4㎎ kg^(-1)으로 점차 감소하였는데 처리에 따라서는 자운영+질소 70%, 자운영+질소 50% 시용구에서 높았다. 3. 벼의 생육은 사질답이 보통답에 비하여 초장 및 간장이 크고 ㎡당경수가 많았고 처리에 따라서는 자운영+질소 50%, 자운영+질소 30%시용구에서 생육이 좋았다. 식물체중의 T-N, P₂O_(5), K₂O함량도 자운영+질소 70%, 자운영+질소 50%시용구에서 많은 편이었다. 4. 시험후 토양의 화학성은 관행에 비하여 보통답의 자운영 시용구에서 OM, CEC, Ava, P₂O_(5)함량이 증가하였고 사질답에서는 CEC가 증가하였다. 5. 벼의 수량은 관행(보통답 5.15Mg ha^(-1), 사질답 5.16Mg ha^(-1))에 비하여 보통답에서는 자운영+질소 70%, 50%, 30%시용구에서 각각 3, 6, 4% 증수되었고, 사질답에서는 자운영+질소 70%, 50%시용구에서 각각 3, 5%증수되었다. 6. 남부 평야지에서 자운영을 재배하여 생초 20Mg ha^(-1)를 녹비로 투입하면 벼를 재배시 질수시용 적정량을 보통답에서는 관행시비량의 30%, 사질답에서는 관행시비량의 50%이였다. This study was conducted to find out an amount of N fertilizer for rice culture followed after milk vetch(MV) cultivated at normal and sandy paddy field in Naju which lies to southern plain region from 1999 to 2001. The amounts of N fertilizer were 110(normal paddy) and 130(sandy paddy)㎏ ha^(-1) at control and 0, 30, 50, 70% of control. At flowering stage of MV, Plant height was 43.6~43.9㎝ and fresh weight was more than that of sandy paddy field. Also, the contents of T-N, T-C, P₂O_(5), CaO, MgO in MV plant cultivated normal paddy field were higher than those of sandy paddy field. Content of NH₄-N in soil was 20.7~47.4㎎ ㎏^(-1) at 7days after transplanting and 6.1~8.1㎎ ㎏^(-1) at 70days after transplanting of rice plant. Content of NH₄-N in soil was high at the treatments of MV+N50% and MV+N70%. Rice plant height, culm length and the number of tiller per ㎡ in sandy paddy field were higher than those of normal paddy field. Growth of rice plant in MV+N70% and MV+N50% was higher than that in others. And the content of T-N, P₂O_(5) and K₂O of rice plant in MV+N70% and MV+N50% were higher than those in others. Chemical properties of soil after experiment were pH 5.1~5.9, OM 15.6~20.9g ㎏^(-1). CEC 10.1~13.8cmol ㎏^(-1) and Ava. P₂O_(5) 152~244㎎ ㎏^(-1). The contents of OM. CEC and Ava. P₂O_(5) in soil applied MV at normal paddy field were higher than those of the control, and the content of CEC in soil applied MV at flowering stage, rice yields of MV+N70%, 50%, MV+N30% were increased 3, 6, 4% more than that of control (5.15Mg ha^(-1)) at normal paddy field. Rice yields of MV+N70%, MV+N50% were increased 3, 5% higher than that of control(5.16Mg ha^(-1)) at sandy paddy field. Nitrogen application rate of normal paddy field was 30%, and sandy paddy field was 50% of conventional fertilization rate when 20Mg ha^(-1) MV cultivated paddy field was inputed for rice culture in the southern plains.

우리나라 연 작업자들의 연폭로 수준에 관한 연구

조인숙,김용배,리갑수,김화성,황규윤,장봉기,이성수,안규동,이병국 순천향대학교 산업의학연구소 1999 순천향산업의학 Vol.5 No.1

To assess lead exposure in Korean lead workers, 2047 male lead workers in 17 lead using industries were studied. Study population were divided into 4 occupation categories such as storage battery industry(type 1), secondary smelting and litharge making industries(type 2), PVC stabilizer making industries(type 3) and primary smelting and related industries (type 4). Blood lead and zinc protoporphyrin in whole blood (ZPP) were selected as an index of lead exposure. Hemoglobin and hematocrit were also checked. Fifteen questionnaires of lead related symptoms were provided to all lead workers and filled up by themselves and confirmed by medical doctors. Personal variables such as age, work duration, smoking and drinking habits were also collected. the results were as follows. 1) The mean blood lead, ZPP and hemoglobin of all lead workers were 29.7+12.6㎍/100㎖, 56.5+38.6㎍/100㎖ and 14.6+1.3 gm/100㎖ respectively. 2) While the mean blood lead of lead workers in type 1, 2, 3 and 4 were 28.6+11.6㎍/100㎖, 46.2+15.3 ㎍/100㎖, 46.8+12.1 ㎍/100㎖ and 26.2+10.2 ㎍/100㎖, the mean value of blood ZPP of those workers were 53.6+32.6 ㎍/100㎖, 108.1+87.1 ㎍/100㎖, 98.9 +54.9 ㎍/100㎖ and 45.8+19.5 ㎍/100㎖ respectively. 3) The percents of lead workers whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 17.6% and 2.1% respectively. Those whose blood lead were 40-59.9 ㎍/100㎖ and over 60.0 ㎍/100㎖ were 15.18% and 0.96% for type 1, 43.59% and 21.79% for type 2, 58.89% and 12.22% for type 3 and 11.82% and 0% for type 4 respectively. 4) The percents of lead workers whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 5.17% and 3.17% respectively. Those whose blood ZPP were 100-149 ㎍/100㎖ and over 150 ㎍/100㎖ were 4.66% and 2.04% for type 1, 10.26% and 25.64% for type 2, 23.33 and 13.33% for type 3 and 1.28% and 0.32% for type 4 respectively. 5) The prevalence rate of smoking and drinking of male lead workers in all lead industries were 70.8% and 71.0% respectively. While the mean blood lead of smoker, non-smoker, drinker and non-drinker were 30.24+12.58 ㎍/100㎖, 28.35+12.7 ㎍/100㎖, 30.24 ㎍/100㎖ and 28.74 ㎍/100㎖ respectively, the mean blood ZPP of those were 55.7+37.1 ㎍/100㎖, 58.4+41.9 ㎍/100㎖, 55.7+36.5 ㎍/100㎖ and 58.4+43.3 ㎍/100㎖ respectively. 6) While the correlation of hematocrit corrected blood lead with other lead exposure variables were higher than non-corrected blood lead, the correlation of log-transformed ZPP with other lead exposure variables were higher than non-corrected blood ZPP. 7) The most frequent symptom among 15 lead related symptom questionnaires was 'general fatigue' and the next one was 'feeling irritated with disturbance' and least one was 'acute abdominal pain around the umbilicus' in all lead workers. The overall prevalence of lead workers in storage battery industry and primary lead smelting industry were higher than secondary lead smelting and PVC stabilizer making industries. 8) The prevalence of lead related symptoms was a little higher in 13 symptoms in smokers than non-smokers and in 14 symptoms in drinker than non-drinkers, but they were not statistically significant. 9) Stepwise multiple regression analysis, using overall symptom prevalence as a dependent variable blood lead, blood ZPP, hemoglobin, age, work duration, drinking and smoking habits as independent variables, indicated that smoking habit, drinking habit and age were significantly contributed to the dependent variable. 10) The slopes of simple linear regression of blood lead (independent variable) with blood ZPP and log-transformed ZPP as dependent variable were different among 4 types of lead industries. The slope of lead industries with low mean blood lead were less steeper than those with high mean blood lead.

원문 : 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향

조봉오 ( Bong Oh Cho ),이인녕 ( In Yeong Lee ),정균근 ( Gyun Geun Jeong ),장창현 ( Chang Hyun Jang ) 한국운동생리학회(구 한국운동과학회) 2014 운동과학 Vol.23 No.3

조봉오, 이인녕, 정균근, 장창현. 좌업 시간과 알코올 섭취가 30대 남자 사무직 근로자의 혈압과 혈관탄성에 미치는 영향. 운동과학, 제23권 3호, 241-248, 2014. 본 연구의 목적은 일과 중 대부분을 좌업근무 형태로 업무를 수행하고, 스트레스로 인해 음주가 잦고, 운동이 부족한 30대 남자 사무직 음주자 15명을 대상으로 좌업 시간과 알코올 섭취가 혈압과 혈관탄성에 미치는 영향을 분석하여 사무직 근로자에게 건강관리에 필요한 정보를 제공하는데 있다. S대학 운동 생리학 실험실에서 사전 인적 사항과 설문을 작성하고, 신장, 체중, 채혈, 혈압, 혈관탄성, BMI를 측정하였다. 알코올 섭취 횟수, 섭취량, 좌업 시간, 그리고 음주 섭취 전과 후 및 시간대별 (10분, 40분, 60분) 혈압과 혈관탄성의 변화를 측정 분석한 결과를 요약하면 다음과 같다. 1) 평균 좌업시간이 9.87시간, 음주횟수 및 음주량은 월 평균 9.13회와 12.47잔 이였다. 2) 알코올 섭취횟수 및 섭취량에 따른 BMI, TC, LDL-C, HDL-C, 혈압과 혈관탄성 비교에서 알코올 섭취횟수에서 좌상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 3) 알코올 섭취 전, 후 비교 분석 결과 우상지와 좌상지의 혈관탄성에서 통계적으로 유의한 차이가 나타났다(p<.05). 4) 알코올 섭취 후 시간대별 우상지 혈관탄성은 통계적으로 유의한 차이를 나타냈다(p<.05). 이상의 결과를 종합해 볼 때, 좌업 시간이 혈압과 혈관탄성에 미치는 영향은 통계적으로 유의하게 나타나지 않았고, 알코올 섭취는 혈관탄성에 통계적으로 유의한 차이를 나타냄을 알 수 있었다. 따라서 이는 직장생활의 스트레스를 음주로 해소하는 경향이 있음을 보여주며 건강에 부정적인 영향을 주고 있음을 알 수 있었다. 또한, 신체가 음주에 적응되어 실험 시 섭취한 적은 양(1/2병)은 1회 12.47잔에 비해 혈압과 혈관탄성에 큰 영향을 미치지 못한 것으로 사료된다. Cho, Bong-Oh, Lee, In-Yeong, Jeong, Gyun-Geun, Jang, Chang-Hyun. Effects of Sedentary Occupation Time and Alcohol Intake on Blood Pressure and Vascular Compliance in 30s Male White-Collar Workers. Exercise Science, 23(3): 241-248. 2014. The purpose of this study was to examine effects of duration of sedentary office work and alcohol intake on blood pressure and vascular compliance in male subjects who were office workers aged between 30 to 39 and frequently drink alcoholic beverages to cope with their stress without exercising for health. The study was to provide health-related information necessary for white-collar workers. We collected data of demographic information, height, weight, blood sample, blood pressure, vascular compliance, and BMI from 15 subjects in S University`s Exercise Physiology Laboratory, and analyzed the frequency and amount of alcohol intake, duration of sedentary work, and changes in blood pressure and vascular compliance at diffident time points (10, 40, and 60 minutes post drinking) from baseline. I t was found that the average time of sedentary work was 9.87 hours, drinking 9.13 times a month on average, 12.47 glasses of alcohol beverages per drink. In comparison of BMI, TC, LDL-C, HDL-C, blood pressure and vascular compliance upon the frequency and amount of alcohol intake, the upper left limb`s vascular compliance had a statistically significant difference (p<.05). In the result of the comparative analysis of pre-and post-drinking, vascular compliance was significantly different in the upper right and left limbs (p<.05). Vascular compliance in the upper right limb after drinking significantly changed (p<.05). As a result, the duration of sedentary work had no statistically significant difference in blood pressure and vascular compliance. T he vascular compliance after drinking h ad a statistically significant difference. This suggested that the result was an index that shows the trend of the office workers releasing their work stress by drinking alcoholic beverages, and that drinking had negative impacts on them. In addition, a small amount of intake (a half bottle) at the test time, after the body was adjusted to drinking, compared with 12.47 glasses per intake, had no great impacts on blood pressure and vascular compliance.