서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

레니텍^(�) 정(말레인산 에날라프릴, 10mg)에 대한 에나레이스 정의 생물학적 동등성

조성희,하용화,홍성제,서성훈,류재환,김동현,이경태 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.3

The purpose of present study was to evaluate the bioequivalence of two enalapril maleate tablets, Renitec^(™) (MSD Korea Ltd.) and Enalace ^(™) (Welfide Korea Ltd.), according to the guidelines of Korea Food Drug Administration (KFDA). Twenty-four normal male volunteers, 22.33±2.55 year in age and 66.54±8.30 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containint 10 ㎎ of enal-april maleate per tablet wre orally administered, blood was taken at predetermined time intervals and concentrations of enalapril in plasma were determined using LC-MS-MS. Pharmacokinetic parameters such as AUC_(t), C_(max) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t) and C_(max) untransformed T_(max). There were no sequence effects between two formulations in these parameters. The 90% confidence intervals for the log transfored data were acceptance range of log0.8 to log1.25(e.g., log1.02∼log1.14 and log1.03∼log1.19 for AUC_(t) and C_(max), respectively). The major parameters, AUC_(t) and C_(max), met the criteria of KDFA for bioequivalence indicating that Enalace^(™) tablet is bioequivalent to Renitec^(™) tablet.

다중 제어루프에 의한 자기부상용 DC-DC 전원장치에 관한 연구

조주현,조정민,전기영,이상집,이승환,오봉환,이훈구,한경희 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

The author present a modified multi-loop algorithm including feedforward for controlling a 55kW step down chopper in the power supply of Maglev. The control law for the duty cycle consists of three terms. The first is the feedforward term which compensates for variations in the input voltage. The second term consists of the difference between the slowly moving inductor current and output current. The third term consists of proportional and integral terms involving the perturbation in the output voltage. This perturvation is derived by subtracting the desired output voltage from the actual output voltage. The proportional and integral action stabilizes the system and minimizes output voltage error. In order to verify the validity of the proposed multi-loop controller, simulation study was tried using Matlab simulink.

사업장 소음 폭로에 의한 일과성 역치 상승과 회복

조수헌,하미나,한상환,주영수,성주헌,강종원,윤덕로,송동빈,이명학,김선태 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

To determine the recovery time from noise-induced temporary threshold shift(TTS), a prospective field study was conducted at three worksites where workers are known to be exposed high level of noise. Subjects were selected according to answers on a questionnaire which inquired about otological history and previous noise exposure, including avocational, military and occupational exposures. After excluding employee with past otologic problems, recent exposure to high level noise, and under medications, total 92 employees participated in the study. Among 92 participants, complete consecutive audiometric examinations were carried out at 0∼2 hours, 5∼7 hours, 14∼16 hours after worktime noise exposure on 26 participants wearing hearing protectors and 22 participants wearing no protective devices. The difference between the hearing level 0∼2 hours after noise exposure and 5∼7 hours is statistically significant by paired t-test(p<0.01). The median recovery times calculated from the data of 22 participants wearing no protective hearing devices are 15.6 hours at 4000Hz, and 7.7 hours, 10.3 hours, 8.4 hours at 1000Hz, 2000Hz and 8000Hz respectively. These data suggest that when measuring the pure tone audiometry for noise exposed workers, at least 16 hours noise-free interval is required.

연쇄상구균을 실험감염시킨 넙치치어의 병리조직학적 관찰

조성환,류시윤,김현수,박배근,김덕환,손화영,윤원기,신창호 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

Pathological observations were examined after abdominal inoculation in 7∼8㎝ sized flounder (Paralichthys olivaceus) with 1X10^7 cfu/㎖ of Streptococcus faecalis. The infected flounder were clinically observed and weighed a fish body at 0, 5, 10, 15, 20, 25, 30 days post inoculation. In infected group, mortality were 70% and feed efficiency were 7.2%. In non-infected group, mortality were 10% and feed efficiency were 18.2%. Macroscopically, the significant lesions were characterized by protrusions and opacity of the eyes and ulcer of the caudal pecuncle. Histopathologically, the lesions were observed a degeneration. necrosis and inflammatory cells in muscle of the caudal peduncle and a degeneration and necrosis of the rod cells and detached retina from the black pigmented layer

液體膜에 의한 Benzene과 n-Hexane 混合物의 分離에 있어서 界面活性劑가 미치는 影響

趙成煥,鄭泰秀 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.1

In the separation of benzene-n-hexane mixture by emulsion liquid membrane in a batch system, the effect of surfactants on the separation factor and the percentage of membrane breakup were investigated over the surfactant concentration ranging from 0.1 to 1.5 wt% at the contact time of 5 and 10 mimutes and the settling time of 5 and 10 minutes. The surfactants used were sodium lauryl sulfate, sodium laurylether sulfate and triethanolamine lauryl sulfate. The separation factor reached its maximum value at the surfactant concentration of 0.5 wt% for all surfactants. In general sodium laurylether sulfate showed larger separation factor than the other two surfactants. The separation factor reached its maximum value at the contact time of 5 minutes for sodium lauryl sulfate and sodium laurylether sulfate and 10 minutes for triethanolamine lauryl sulfate. It was found that the percentage of membrane breakup reached its minmum values and the separation factor showed its maximum values at the surfactant concentration of 0.5 wt% for all three surfactants, which confirmed that efficient separation could be effected when emulsion liquid membranes were stable because of their low membrane breakup.

레미콘 타설 작업 중 발생한 피부 궤양 1례

조수헌,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

The case was described of a 43 year old male who developed burns of the both shins as a result of handling wet cement. After wet cement was spilled into the rubber boots he was wearing, he experienced painful erythema of both lower legs. Several weeks later, medical examination revealed dirty and granulated ulceration of the both shins. The largest ulcer, about 18 by 10 centimeters, was located on the anterior aspect of left lower leg. We concluded that this skin problem resulted from the extreme alkalinity of calcium hydroxide in wet cement, combined with the effects of pressure and occlusion against the skin.

밤나무 耐寒性品種 選拔에 관한 硏究 : 耐霜性을 中心으로 Castanea crenata S. et Z.

趙台煥,洪性珏 건국대학교 1980 學術誌 Vol.24 No.2

Seasonal change in freezing resistance of buds and xylem parenchyma of 32 chestnut cultivars (Castanea crenata S. et Z.) were studied during winter of 1977 to 1978. Dehardening responses of the hardened twigs in mid-winter were examined by being exposed to high temperature of 20℃ for 3 to 15 days. Rehardening responses of the artificially or naturally dehardened twigs were tested by being exposed to short or long-term low temperatures of 7℃ or -10℃. The freezing resistance of graft unions of two cultivars was compared to that of the upper and lower parts of twigs of the seedlings at mid winter and early spring. Variation in freezing resistance among 32 chestnut cultivars at the late fall of 1977 and the early spring of 1978 were much greater than that of the early and mid-winter. The little variation in freezing resistance at mid-winter suggested that in selecting most cold hardy cultivar the speed of hardening and dehardening in cold and warm condition respectively are more important factors than the magnitude of maximum freezing resistance which could have been obtained during mid-winter or by artificial hardening, The warm temperature of 20℃ for 3 to 15 days decreased freezing resistance of the fully hardened twigs at mid-winter. The low temperature of 7 or -10℃ in short or long term increased freezing resistance of the twigs which had been dehardened either by artificial high temperature treatment or by natural conditions in early spring. The difference in freezing resistance in early spring among cultivars coincided with the difference in the sensitivity in hardening by the low temperature treatment and/or in delaying dehardening by warm temperature treatment. In the late fall and the early spring buds of all cultivars showed less freezing resistance than xylem parenchyma. In the contrast the xylem parenchyma became less hardy than the buds as the cold acelimation progreesed toward mid-winter and as the rehardening occurred on the dehardened twigs at early spring by low temperature treatment. In graft unions the upper parts of twigs showed more freezing resistance than graft parts in mid-winter. But in early spring the cold hardiness of the two parts are conversely changed each other. This phenomena frill be a good index for distinguishing midwinter from late frost damage.

대명천 유수지의 식생유형 및 생태적 특성에 관한 연구

조현제,오승환 대구산업정보대학 2001 논문집 Vol.15 No.-

The present vegetation established on Daemyongcheon wetland, were studied phytosociologically, with special reference to its ecological conservation and management. Vegetation types of this area were classified into two higher units(community level), six lower units and five lowest units, giving twenty management areas. Phragmites communis occupied the highest ecological niche. The species diversity(H'), the evenness(J') and the maximum of species diversity(H'max) were showed 3.03±0.38, 0.90±0.06 and 3.42±0.52, respectively. According to the constancy diagram of the component species, the lower classes(< I) have 84.5% in the plant species occurring to this area and the higher classes(> III) only 3.6%. The ratio of naturalized plants showed 40%, which was much higher than the nearby wetland(Dalseong wetland 19.4% and Daelim wetland 15.3%).

개에서 관찰된 모기질세포종의 증례보고

조성환,손화영,김혜성,최종윤,류시윤,박배근,윤원기,홍성혁,김덕환 충남대학교 수의과대학 동물의과학연구소 2002 動物醫科學硏究誌 Vol.10 No.-

Pilomatricoma was histopathologically diagnosed in a 2.5-year-old male Alaskan malamute. The patient was referred to Chungnam National University, Veterinary Medical Teaching Hospital with solitary, firm and well-circumscribed mass at shoulder. Grossly, the mass was dome shaped to tumor like and 10 x 8 x 5㎝ in size. Some lesions had gritty or bony consistency and was chalky when sectioned Histopathologic feature included mumerous clusters of tightly arranged, basaloid cells with evenly distributed chromatin and ghost cells were characterized by a central unstained zone. The ghost cells often become calcified and osseous metaplasia was also present.