당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

유아 그림동화책에 나타난 성 역할 분석

조한숙,문혁준 가톨릭대학교 생활과학연구소 2002 생활과학연구논집 Vol.22 No.1

The purpose of study is to analyse the sex-role stereotyping for male and female character in the picture fairy tale, and to supply a fundamental data to help the early childhood have an equal sex-role character. The results are as follows: First, among the characters in the picture fairy tales, the most popular gender is neuter and the next one is female, and male in sentences, but male, neuter and female in the picture. Second, the most popular gender for the main character is male and the next one is neuter and female. Third, as a result of the analysis on the subjects for gender with the sentences and the picture stories in the fairy tales, 「Problem-solving capability·Creativity」, 「Wisdom·Knowledge」, 「Nature·Love of animals」 are emphasized for male and female in the sentences, but 「Problem-solving capability·Creativity」 for male and 「Nature·Love of animals」 for female in the picture book. Forth, as a result of analysis on the job tendency of male and female adults in the picture fairy tales, males appears to engage in various kinds of jobs. On the other hand, female is usually described as mostly house wives in the limited jobs. Fifth, in the picture fairy tales, male adults often appear to engage in social jobs, but female adults in household affairs. Male children usually do dynamic activities, but female children do static work. Sixth, as a result of analysis on the activity place outdoors and indoor for the main character, hero tends to act outdoor more often than heroine.

콘크리트 포장의 하부 지지력계수 산정식 개발

조윤호,한상기,김준형 중앙대학교 기술과학연구소 1999 기술과학연구소 논문집 Vol.29 No.-

외국의 설계 지침을 근간으로 콘크리트 포장을 설계하고 있는 국내 포장 기술자들은 흙의 지지력 계수 추정에 어려움을 겪고 있다. 길바탕흙(Roadbed Soil)의 평판재하실험 결과(??)를 선택층 및 하나 혹은 여러 층위의 지지력계수(??)로 변환하는 것은 현 설계 지침에 상세한 과정이 없으므로 혼란이 가중되고 있다. 이에 대하여 본 논문은 흙의 지지력계수 산정과정 전반에 걸쳐 국내의 문제점을 살펴보고, 바람직한 설계 방향을 제시하였다. 국내에 존재하는 포장의 형식을 조사하여 대표적인 보조기층재료와 두께 따라 ??값에서 ??값을 추정하는 설계 입력변수 변환 모형을 제시하였는데, 포장 거동 해석 모형은 AASHTO 추정식에 사용했던 다탄성 해석이론인 ELSYM5가 사용되었다. 역학적 모형 해석에 어려움을 겪는 기술자들이 간편하게 사용할 모형을 개발였는데 기층 및 보조 기층의 두께 및 재료 물성에 따라 총 990회의 거동 해석이 진행되었고, 회귀 분석을 이용하여 추정모형을 선정하였다. 또한 제시된 회귀식은 기존의 개발 모형과 비교를 통해 실무 적용이 타당하다고 판단하였다. Design of concrete pavement in Korea is mainly based on the guide developed from the AASHTO. However, many input parameters were not calibrated for the materials used in the highway. Subgrade modulus for the rigid pavement could not be correctly estimated due to lack of procedure to transfer modulus of subgrade reaction(??) to composite modulus of subgrade reaction(??), for example. This paper describes the way how to develop transforming equation and the model for estimating ??. Typical concrete sections were selected from the survey of pavement constructed in airport and highway. A layered elastic model, ELSYM5, that shows the behavior of concrete pavement under traffic loading was adapted for calculation of theoretical subgrade modules. Total 990 of calculation were performed. Regression model was suggested for the design based purely on analytical work so that further research work to verify the model from the field should be carried out.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

장기간 댄스스포츠가 호흡순환 기능 및 심폐지구력에 미치는 효과

조현철,김준희,한주희 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

The purpose of this study was to evaluate the effects in respire-circulatory function and cadio-pulmonary endurance capacity. Twelve females(trained 6, untrained 6) participated in dancesport program that is 90min/day, 2day/week for 20weeks. The results were obtained as follow : 1. No significant difference was found in heart rate, ventilation and respiration rate among pretest, after 10 weeks and 20 weeks of dance program and between trained and untrained group. 2. Significant differenced was found in VCO₂between pretest and 20Weeks later in untrained group. 3. There was significantly increased VO₂max in 20 weeks dance program later compared with pretest and significant difference between groups. 4. There was no significant difference in ventilatory threshold and exercise time was not significant difference among trials and between groups. Conclusively, respiro-circulatory function and cardio-pulmonary endurance capacity were not changed at submaximal stage of excise test but those were significantly increased at maximal of exercise test during 20 weeks. Therefore, it is suggested that long term dancesport exercise program is expected more effective on the repiro-circulation function and cardio-pulmonary endurance capacity.

Corynebacterium sp. K-199가 생산하는 단백질성 생물용집제

김영준,최양문,조홍연,양한철 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

미생물응집제를 개발하기 위하여 자연계로부터 방선균 600여 균주와 보관균주를 대상으로 응집활성이 우수한 균주를 선별하고 동정한 결과 corynebacteium 속으로 동정되었다. 응집제 생산을 위한 최적조건은 2% glycerol, 0.4% peptone, 0.1% yeast extract, 0.3% K_2HPO_4, 0.1% CaCO_3, 0.05% NaCl, 0.1% MgSO_4·7H_2O, pH 7.5의 배지 100 ml을 500ml baffle flask에 넣고 96시간 회전진탕배양할 때였으며 상기의 조건으로 jar fermentor 배양시 96시간에서 780 units/ml의 응집활성을 나타내었다. 응집물질은 pronase 처리와 periodate 산화에 의해 각각 무처리구와 13%와 106%의 활성을 나타냄으로써 응집활성은 주로 단백질에 기이함을 알 수 있다. About 600 microorganisms isolated form soil, marsh, compost, etc. were examined for their flocculating ability in the kaolin suspension and swine wastewater. Among them, K-199 was the best producer of flocculant and was identified to be a species belong to the genus corynebacteium. The maximum production of the flocculant from Corynebacterium sp. K-199 was observed in culture medium containing 2% glycerol, 0.4% peptone, 0.3% K_2HPO_4, 0.1% CaCO_3, 0.05% NaCl, 0.1% yeast extract, 0.1% MgSO_4·7H_2O and initial pH 7.5 when cultured with rotary shaker controlled at 25℃ and 150 rpm. Under the optimal culture condition with jar fermentor, the maximum production was reached to flocculating activity of 780 units/ml after 4 days. From the results of the activity be fully maintained by periodate oxidization, it suggests that the activity is due to the protein.

만성 부비동염에서 수술전후 후각변화

이준한,조성일,허준 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.3

Background and Objectives: Recently, there has been an increase of olfactory disorders due to many etiologies and chronic paranasal sinusitis is the most common etiology of olfactory dysfunction. Functional endoscopic sinus surgery(FESS) is now the surgical procedure of choice for treating chronic sinusitis in patients of all ages. We studied the effect of the surgery on olfaction of patients with chronic paranasal sinusitis. Materials and Methods: In order to study the effect of age, as well as the influence of smoking on olfaction in clinical states, we examined olfactory ability using the T&T olfactometer. A preoperative and postoperative evaluation of the olfactory function was carried out in 47 patients. According to the preoperative recognition threshold, olfactory function of all patients were divided into five groups. Results: The group 1 was normal, group 2 was mild decreased, group 3 was moderate decreased, group 4 was severe decreased and group 5 was anosmia. Almost patients were improved on olfaction in the postoperative state. However, 7 patients who were more than 40 years old at the time of surgery, and currently smoking, had a significant deficit of olfaction in the preoperative stage and even in the postoperative stage. Conclusion: These results indicate that smoking has adverse effects on olfactory ability, especially for older patients.

비중격에 발생한 골수외 형질세포종 1예

이준한,도남용,조성일 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Plasmacytoma is an uncommon tumor that arises from malignant proliferation of a type of B-cell lymphocyte. Most plasma cell tumors present as multiple myeloma. Solitary plasmacytomas are classified as medullary or extramedullary. Among them, extramedullary plasmacytoma consists of 4% of all plasma cell tumors and is found predominantly in the head and neck region. The most frequent sites are the paranasal sinus, nasal cavity, and nasopharynx but, extramedullary plasmacytoma originated from nasal septum is rare. If histologic diagnosis of plasmacytoma is confirmed, all screening tests are necessary to rule out multiple myeloma. The primary treatment is radiotherapy, but surgery may also be required. We experienced a case of extramedullary plasmacytoma that originated from the nasal septum in a 62-year-old woman. She was treated with combined therapy. Systemic evaluations were done and there was no evidence of systemic involvement. After treatment, she is now well without any symptoms and evidence of recurrence. So we report this case with a review of the literature.

열대 지역에서 통일형 초다수성 벼 품종의 생육 및 수량성 비교

이지윤,준현,성환,손영보,송유천,한상익,박동수,권영업,이철원,이종희 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2