다발성 악하선 타석

도남용 中央醫學社 1988 中央醫學 Vol.53 No.10

The author has recently experienced a case of two salivary stones in the submandibular gland on the right side. A 35 year old man visited the department of Otolaryngology Chosun University, on 4 August 1988 with complaints of walnut sized,"tender swelling on the right submandibular region and mastication difficulty. These symptoms have been graudally developed and aggrevated for past 2 years. Physical examination was not revealed fistula or inflammation on the posterior portion of the right side mouth floor. Plain A-P and right lateral mandibular X-ray views and sialography revealed a large, oval shaped radio-opaque density on the right submandibular region. Through an external approach under the general anesthesia, extirpation of the gland with stone removal was done. The removed two stones were contact with each other. Two stones were 1.5 x 1.5 x 1 cm. and 1 x 1 x 1 cm. in each size, 4.0 gm in weight, grayish-white in color, and the chemical composition of the stones were principally calcium phosphate. The extirpated gland was 3 x 2 x 2 cm in size and revealed chronic sialoadenitis on biopsy.

상부 경추 신경근 (C3 root)에서 발생한 신경초종 1례

도남용,이도용,박성용,박준희 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Neurilemmoma is a relatively rare benign tumor which may be derived from nerve sheath of the peripheral and cranial nerve, and characterized by solitary occurrence, with sharp demarcation and encapsulation. In spite of their rarity, a high proportion of these growth are situated about the head and neck. About 30% of the disease is found in the head and neck region and the most common single site of origin is known to be the acoustic nerve. Thus, described that case involving the upper cervical spine is rare. We recently had the opportunity to care for a man with a cervical spinal neurilemmoma including affected nerve root at C3 level. When the tumor is derived from a root which is assumed to be important for extremity functions, it is still controversial whether that nerve root should be totally resected. A review of the current literature and intraoperative management will be presented to further define these concepts.

일측성 악하선 무형성증 2예

도남용,조성일 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

Aplasia or agenesis of the salivary gland is an uncommon disorder. Unilateral aplasia of the submandibular gland is an extremely rare disorder. Salivary gland aplasia may occur either in isolation or in association with other developmental anomalities, such as atresia of the lacrimal pucta, mandibulofacial dysostosis or congenital malformations of the temporomandibular component. Clinically, patients may be asymptomatic or may present with dryness of the mouth, difficulty in swallowing, and dental caries. The authors experienced two cases of incidentally detected unilateral aplasia of the submandibular gland demonstrated by computed tomography. So we present this cases with review of literatures.

안와를 침범한 거대한 전두동 점액낭종 I 례 : 증례보고

도남용,박성용,박영균 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

The term mucocele was introduced by Rollet in 1896 and Onodi gave the first histologic description in 1901. Paranasal sinus mucocele is the slowly expanding benign lesion which can occur as a result of trauma and spontaneous obstruction of sinus ostium or ostial tract. Mucoceles most frequently ahse from the frontal sinus and anterior ethmoid air cells, Presenting with proptosis, frontal headaches and reduced ocular mobility, especially on upward gaze. Since it may destruct the adjacent bony structure by pressure, early diagnosis and proper treatment are necessary. Recently we experienced on huge mucocele involving frontal and anterior ethmoid sinus and expanding onto left orbit, which was treated with endoscopic surgical procedure.

비강 및 부비동에서 발생한 악성 흑색종 1례

도남용,최지윤,이홍영 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Malignant melanoma aries from melanocyte, which has the ability to synthesize the pigment melanin. Melanocytes are derivations of neural crest cells and widely distributed throughout all cutaneous and mucosal surfaces. Overall, 20% of all malignant melanomas arise in the head and neck, of which only 10% affect the mucous membranes. Less than 1% of all malignant melanomas affect the nasal cavity. The authors experienced a case of primary malignant melanoma originated in left nasal cavity and paranasal sinus, and the patient had been treated by wide excision of the tumor with Weber-Furguson approach and postoperative irradiation. We report a case of primary malignant melanoma on the nasal cavity and paranasal sinus of 49 years old female patient with review of literature.

급성 부비동염과 동반된 안와 합병증

도남용,임태승,김종희,김성렬 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3

Acute paranasal sinusitis is frequently encountered in medical practice and is managed without complication in the majority of cases. But, paranasal sinus inflammation may invade the orbit because paranasal sinuses are close to the orbital wall. Orbital inflammation is the most common complication of acute paranasal sinusitis and lead to blindness, intracranial complications, and death. Orbital complications of acute paranasal sinusitis are thought to arise when the infection spreads to the orbit by direct extension, local thrombophlebitis, or less commonly infected thromboemboli along valveless venous connections. Diagnosis of orbital complication requires a thorough history and physical examination, including an ophthalmologic evaluation. Computed tomography is frequently required as an adjunct in assessing the clinical manifestations of advanced disease, and it can assist the physician in surgical planning if required. Most orbital infections respond to medical therapy. Some cases require surgical intervention. We report three cases that have required surgical intervention, with a review of related literatures.

비두부형 모균증의 임상적 고찰

도남용,이준한,동근우 대한이비인후과학회 2005 대한이비인후과학회지 두경부외과학 Vol.48 No.10

Background and Objectives:Rhinocerebral mucormycosis is recognized as a potentially aggressive and commonly fatal fungal infection. The classic presentation involves nasal mucosa and the invasion of the paranasal sinuses and orbit. Treatment includes aggressive debridement, systemic antifungal therapy, and control of underlying comorbid factors. This study aimed to investigate the clinical feature of rhinocerebral mucormycosis and to determine relationships among the underlying disease, extent of mucormycosis, initial time of surgical intervention and prognosis. Subjects and Method:Five cases of mucormycosis were retrospectively reviewed. Prognosis was analyzed according to predisposing factors including the underlying disease, extent of disease and intial time of surgical intervention. Resuits:A 5-year overall survival rate of the patients with mucormycosis was 60%. There was significant survival gain in the group for which the underlying disease was well controlled and extent of disease was limited, No significant difference in survival was observed according to duration between symptom onset and surgical intervention. Conclusion:Survival is usually determined at the very early period of treatment. The most important prognostic factor is optimal control of the underlying disease and extent of disease.

비·부비동 종양의 신생혈관 형성에서 COX-2 및 VEGF의 역할

도남용,박성용,조성일,윤혁수,박선홍,박영균,권대승,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : COX-2, the inducible form of cyclooxygenase(COX), is upregulated in transformed cells and in malignant cells, which have important roles in promotion of colorectal carcinogenesis, invasiveness and angiogenesis. Vascular endothelial growth factor(VEGF) may act as endothelial cell mitogen in various cancer tissues. It will increase tumor growth and angiogenesis. Aims of this study were to asses COX-2/VEGF expression and it's clinical correlation in sinonasal tumors and to investigate the effects on angiogenesis also. Materials and Method : The study samples were obtained from surgical removal of 27 cases of inverted papilloma(IPs), 5 cases of IP with malignant transformation(IP-MT), 16 cases of Squamous cell carcinoma(SCC) in sinonasal cavity COX-2 and VEGF expressions were assessed by immunohistochemical staining. Synchronism of COX-2/VEGF expression in one tumor cell was demonstrated with double immunofluorescence technique. Results : The expression rates of COX-2 were 37% in IP, 80% in IP-MT and 100% in SCC. The positive rates of VEGF were 29 6% in IP, 100% in IP-MT and SCC. COX-2 and VEGF expressions were increased as tumor progressed, and there is a positive correlation between COX-2 &EGF expressions. All clinical features which were compared are not associated with COX-2 &EGF expressions except malignant change in IP(p=0 028). Synchronism of COX-2/VEGF expressions was noted in all positive immunostaining samples. Conclusion : These findings suggest the role of COX-2 pathway could be involved in sinonasal tumor angiogenesis, which is modulated by VEGF COX-2 may act as autocrine factor in VEGF expression. There is a potential role for selective COX-2 inhibitors in the treatment of these lesions.

삼출성중이염의 임상적 고찰

도남용 中央醫學社 1988 中央醫學 Vol.53 No.12

The author experienced 110 patients of otitis media with effusion from Jan., 1985 to Dec., 1987 and the results were as follows; 1) The sex distribution showed 64 male cases and 46 female cases and bilateral effusion was more frequent than one side. 2) The 67 patients were attacked in spring and winter (61 %). 3) In the preoperative tympanogram, there were 10 %with type A, 77 %with type B and 13 % with type C. 4) The rhinitis and sinusitis (56 %) were considered as the main preceeding diseases. 5) Drum retraction was seen in 53 % and turbid drum without retraction in 18 %. 6) The nature of middle ear fluid was 48 % serous exudate, 36 % mucoid exudate, 2 % purulent exudate and 14 % scanty or no fluid. 7) The 56 patients were treated with myringotomy and ventilation tube insertion.

특강 : 상악동 질환의 진단과 치료

도남용 대한치주과학회 2005 대한치주과학회 학술대회자료집 Vol.2005 No.1