2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

농업용수 수질기준 T-N 항목 설정을 위한 벼생육 실험

최선화,김호일,윤경섭,최이송,오종민 한국물환경학회 2004 한국물환경학회지 Vol.20 No.3

The present water quality standards for agricultural were established without considering the effects of water quality on the safety, growth, yield and quality of crops. This study was carried out to investigate the effects of irrigation water quality on the growth, yield, and grain quality of rice, and to acquire basic knowledges to set up water quality standards for irrigation. The field and pot experiments were conducted with irrigation water that was previously adjusted four concentrations (control, 5, 10, 20 ㎎/L) and six concentrations (control, 5, 10, 15, 20, 30 ㎎/L) by NH₄NO₃ solution and replicated three and four times with randomized block design, respectively. The results of this study showed that the inorganic nutrient of rice plant, rice protein contents and number of panicle tended to increase as the T-N concentration in irrigation water was increased. In addition, grain yield at T-N 10 ㎎/L and 20㎎/L were significantly higher than the control at the field experiment. From the pot experiment at T-N 30 ㎎/L, the percentage of head rice was slightly lower due to the increase of green kernel and white belly/core kernel.

농업용수수질기준 제정을 위한 T-P 항목의 검증실험

최선화,김영일,김민호,이변우,오종민 경희대학교 2003 環境硏究 論文集 Vol.12 No.-

This study was carried out to nvestigate- the effects of T-P concentrations in irrigation water on the growth, yield, and grain quality of rice. It acquire fundamental knowledges to set up irrigation water quality standards. The pot experiment was conducted with 5 treatments using irrigation water. It consisted of various total phosphorus concentrations (control, 1, 2, 5, 10 mg/L) and replicated four times with randomized block design. the results of this study showed that as t-P concentrations in irrigation water increases, plant height tended to increase. Dry weight of rice plant at t-P 10 mg/L was significantly higher than the control. However, t-P in irrigation water did not affect plant height, tiller number, plant; dry weight, yield, and quality of rice.

Aspergillus oryzae를 이용한 캡슐형 메주의 품질특성

최재훈,권선화,이상원,남상해,최상도,박석규 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

전통메주의 표면에서 발행하는 야생곰팡이 착생, 유해곰팡이에 대한 mycotoxin 생성 및 메주 표면의 과도한 건조 등을 해결하기 위하여 메주 외층에 Aspergillus oryzae로 만든 쌀 종국(0.3%, w/w)을 혼합시킨 증자 검정콩으로 얇게 코팅한 후, 25℃, 상대습도 80%에서 14일간 발효시킨 캡슐형 메주를 개발하였다. 캡슐형 메주의 표면에서 야생곰팡이의 오염은 발견되지 않았으나, 대조구 메주는 12일 이후에 푸른곰팡이가 많이 관찰되었다. 메주의 수분 함량은 평균 32.7%로서 34.7~29.4%의 범위를 나타내었다. 적정산도는 캡슐형 메주가 대조구 메주보다 높게 나타났으며, 대두 캡슐형 메주와 검정콩 캡슐형 메주는 비슷하게 나타났다. 유리당의 함량은 검정콩 캡슐형 메주가 123.98㎎%로 대조구 메주 15.02㎎%와 대두 캡슐형 메주 59.85㎎%보다 각각 10배, 2.1배, 높게 나타났다. 아미노산성 질소의 함량은 대조구 메주에서 147.00㎎%였으며, 검정콩 캡슐형 메주는 255.50㎎%로서 대두 캡슐형 메주 187.25㎎%보다 약 1.37배 높은 함량을 나타내었다. 총 유기산의 함량은 캡슐형 메주(대두 119.98㎎%, 검정콩 95.94㎎%)가 대조두 메주(26.44㎎%)보다 함량이 높게 나타났으며, 캡슐화에 따라 lactic acid와 malic acid 가 가장 큰 변화를 나타내었다. 색차계 색도는 검정콩 캡슐형 메주가 대두 캡슐형 메주보다 명도값(L)이 크게 나타났으며 지방산 조성은 메주의 종류에 따라 큰 차이를 나타내지 않았다. 총 유리 아미노산의 함량은 검정콩 캡슐형 메주(1039.70㎎%)가 대두 캡슐형 메주 (556.07㎎%)와 대조구 메주(236.45㎎%) 비하여 각각 2.4배, 4.4배 높았다. In order to improve some problems such as contamination of undersirable mold, mycotoxin production and excessive drying on the surface of traditional meju, we developed a capsule type-meju(CM) coated with steamed black bean and Aspergillus oryzae - rice koji(0.3%, w/w) mixture to surface of traditional meju and fermented at 25℃ for 14 days under 80% relative hunmidity. Contamination of undersirable mold on the surface of CM was not detected within 2 weeks and some genus Penicillium molds on control meju without koji were found naturally after 12 days of fermentation. The moisture content of meju was showed to be in the range of 34.7 - 29.4% being 32.7(w/w) of mean value. Titratable acidities in CMs prepared with black bean(BCM) and soybean(SCM) were much higher than that in control meju, and BCM was similar to SCM. Free sugar content in BCM(123.98 ㎎%) was 10 times and 2.1 times higher than that in control meju(15.02 ㎎%) and SCM(59.85㎎%), respectively. Amino type nitrogen content in control meju was 147.00 ㎎% and its content in BCM(255.50㎎%) was 1.37 times higher than that in SCM(187.25 mg%). Total organic acid content in BCM(95.98㎎%) and SCM(119.98㎎%) were much higher than that in control meju(26.44 ㎎%), and then latic and malic acid contents were markedly changed according to capsulation of meju. Lightness value(l) of Hunter color index was much higher in BCM than in SCM. Fatty acid composition of CM was not different as compared to control meju. Total free amino acid content in BCM(1039.70 ㎎%) was 4.4 times and 2.4 times higher than that in control meju(236.45 ㎎%) and SCM(556.07 ㎎%), respectively.

TCP 트래픽의 성능 측정

최우철,송화선,정영준 강원대학교 정보통신연구소 2003 정보통신논문지 Vol.7 No.-

The performance evaluation of Internet traffics has been performed by factors such as RTT and packet loss. This individual evaluation method has some difficulties in determining service quality due to interoperations between those factors. This paper presents a hybrid performance evaluation formula for TCP traffics, which uses both RTT and packet loss. The formula has been defined by an interpretation model, which is derived from a TCP throughtput rate in congestion environment and a packet retransmission mechanism. The proposed formula has been applied to a data set collected from the KREN performance measure, and then has been shown to easily determine TCP performance variations. Thus, the proposed scheme can be used for a SLA monitoring system.

만경강 상류 유역의 수질 및 오염부하량 특성

최선화,이광야,오종민 경희대학교 2005 環境硏究 論文集 Vol.14 No.-

This study is to analyze characteristics of pollutant load on the upper Mankyeong river watershed with combined urban and rural area during the irrigation season. The magnitude of the runoff and the BOD were by order of Daechon, Jeonju stream, Gosan stream and Soyang stream. The amount of organic matter in the downstream was higher than the one in the upstream. The magnitude of the T-N was by order of Daechon, Jeonju, Soyang and Gosan. And T-P was by order of Daechon, Jeonju, Gosan and Soyang. As for T-N, 92% of the Jeonju stream transferred into the Daechon. On the other hand, T-P in Daechon decreased by 40% in comparison with the Jeonju stream, which is due to dilution and deposition while transferring. While period of irrigation, it was found that the quality of water at upstream of Mankyeong river in Gosan and Soyang were good, but a decline of water quality can be seen after joining with Jeonju. The ratio Jeonju to Daechon of BOD, T-N, and T-P were 55%, 92%, 163% respectively. Water quality at Jeonju stream get deteriorating and at Daechon point expect to get worse. From the concentration and load of pollution, Daechon point is more serious than Gosan and Soyan stream point.

사상성 조류매트 고속산화지의 수질정화효율 평가

최선화,안열,오종민 경희대학교 2005 環境硏究 論文集 Vol.14 No.-

This study was carried out to evaluate of water purification in oxidation pond with filaments algae mat. It is the water treatment process in the small rural streams to remove the organic materials and nutrients. We used the filaments algae mat(FAM) which selectively predominate to prevent the additional contamination by algae outflow. The removal efficiencies of COD, SS, T-N and T-P in oxidation pond with filaments algae mat were -2.5%, 84.7%, 63.9% and 89.2%, respectively. The removal efficiencies of T-N and T-P which are nutrients index were high. Results of this study would help us to determine the possibility of using the water treatment on the contaminated small rural streams.

Head-Space SPME에 의한 생체시료 중 메스암페타민류 분석(Ⅱ)

최화경,양원경,한은영,최상길,정희선 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

무도 종목별 스포츠 적성 체력 판별에 영향을 미치는 체력 요인 분석

최종삼,윤익선,봉화선 龍仁大學校 武道硏究所 2004 武道硏究所誌 Vol.15 No.1

The standard of value of winning in sports has become much important and the standard of physical strength improvement serves as the most important conformity for assessment of players, thus, it is required to identify what are the major factors for performance of play to improve the technique of Yongmoodo, Taekwondo and Kumdo athletes. Accordingly, researchers, scientists, and leaders of sports analyse the factors for performance of play focussed on how to improve the performance of play, and anticipate to analyse, to be informed of, and to assess the players and training result based on the result of play. Thus, the study is designed to find out the physical factors for decision of records of play in university students Yongmoodo, Taekwondo and Kumdo athletes under planned training and to identify physical factors of play performance of Yongmoodo, Taekwondo and Kumdo athletes. SPSS V11.0 ststistic program was used in processing of data in this study. Stepwise discriminant analysis was applied in identification of major assessment items showing the difference between the groups, and partial F-test statistic was utilized, on the assumption that contribution ratios of each variable are the difference between the groups, to assess their statistical significance and to make decision whether to select the variables. 1. In determination of Yongmoodo, Taekwondo and Kumdo athletes by physical strength, statistic showed statistical significance with 5% of significance level. 2. The order of contribution of variables that determine the performance of play as well as run to 100m, back strength, abdominal muscular endurance, flexibility, muscular endurance of upper arms are Yongmoodo athletes, thus, grip strength, agility and 1 mile run are Taekwondo and Kumdo athletes. 3. In therms of accuracy of the reclassification of determination factors as sports talent fitness of martial-arts event style, the reclassification into Yongmoodo(78.8%) and Taekwondo(86.8%) was higher compare that of Kumdo(37.7%). In therms of accuracy of the reclassification of determination factors as sports talent fitness of all martial-arts event style, the reclassification into Yongmoodo, Taekwondo and Kumdo were 69.8%.

Coumarin을 포함하는 새로운 형광 크라운 에테르의 합성(3)

최선화,장승현 한국공업화학회 2004 응용화학 Vol.8 No.2

We report herein synthetic results obtained new types of crown ethers containing coumarin group. Crown ethers containing coumarin group 1~3 are hydroxymethyl-15-crown-5-ether linked with 4-hydroxy coumarin-4-acetic acid byesterification reaction. Crown ethers containing coumarin group 1~3 have different cavity in each crown ether rings. The 12-crown-4 ether with coumarin 1 has the smallest cavity size. The 15-crown-5 ether with coumarine 2 has the medium cavity size. The 18-crown-6 ether with coumarin 3 has the largest cavity size. Therefore each crown ether with coumarin group will recognize different ionic radius metal. Because of different hole size in crown ethers, these crown ethers seem to be had different selectivity in luminescent sensors. The crown ethers with coumarine 1~3 synthesized hydroxymethyl-15-crown-5-ether and 4-hydroxy coumarin-4-acetic acid same ratio at one to one. The synthesized crown ethers were characterized respectively by IR, NMR. GC-Mass.