우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

2007년 대한감염학회 권장 성인 예방접종 권장안

강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

5세 남아의 Influenza 종격동기종 및 대엽성 폐렴 1례

오희성,한유진,연은경,선동신,송준환,박경배,박준수,김영통,남해선,최영진,김용배 순천향의학연구소 2009 Journal of Soonchunhyang Medical Science Vol.14 No.3S

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15C 이탈리아 메디치家 빌라庭園의 造營實態 및 空間構成特性分析

최종희,김용기 成均館大學校 科學技術硏究所 2003 論文集 Vol.54 No.1

This study aims to discussion analysis of actual condition and spatial organization characteristics of Italian Medici villa gardens in 15th century. In this study was selected the cases of the 5 gardens that were constructed as the suburban house of Podesta Medici family in 15th century. To do this, it was studied in two ways: Analysis of the present conditions and photographing, research materials about the form of physical structure and review historical documents. The result of analysis in the sight of the location and spatial structure was good matched. At the beginning, he concept of construction of the Medici villa gardens had been expressed as intrinsic nature and an ideal of a quiet life of suburb, enjoying of nature of philosopher, poets, politician etc.. The spatial organization of the Medici Villa gardens was built the hill area where were located in a very good geographical feature with nice looking at mountains and rivers. In the exterior space patterns of the Medici Villa gardens was imported borrowed scenery of surrounding landscape and while placed arranging various constituent elements of the casino, terrace, parterre, ninfeo, grotta in trying to formalize the landscape. The result of this study, the political and social, technical phenomena which constitute the physical construction pattern affected the locational property and the spatial organization of the neighbor on Medici Villa gardens.

運動選手들의 傷害에 관한 調査硏究

崔龍魚,朴泳熙 韓國體育大學校附屬 體育科學硏究所 1983 韓國體育大學校附屬 體育科學硏究所論文集 Vol.2 No.1

The authors intended to study on the athletic injury in Korea National College of Physical Education students. A follow-up study of subjects of this note was total 504 athletes, during the one year period from july 1982 to june 1983. The result were summerized as follows: 1. The rate(%) of distribution on the incidence cases of athletic injury were Taekwondo(602.33%), Track & Field(571.88%), Badminton(478.95%), Weight-lifting(447.62%), Wrestling443.14%), Judo(431.58), Gymnastics(428.57%), Boxing(362.75%), Fencing(281.25%), Skating(258.33%), Shooting(196.43%), Cycling(178.95%), Field hockey(175.0%), Hand ball(154.55%), Table tennis(140.0%), Rowing(83.33%), Biathlon(71.43%), Archery(37.5%), respectively. 2. The morbility rate for 1.000 of athletic injury on the physical area were 908.7 of knee joint, 815.5 of lumber vertebrae, 601.2 of intertasal joint, 398.8 of shoulder joint, 299.6 of wrist joint, 190.5 of thracic vertebrae and rib, 176.6 of elbow joint, 51.6 of hip joint and 140.9 of other's, respectively. 3. Each athletes had 3.5 case injury experiences. 4. The highest incidence rate(%) of shoulder injury in athletes were swimming and weight-lifting, that of lumber vertebrae of rowing, that of thoracic vertebrae % rib of wretling, that of hip joint of rowing and taekwondo, that of wristjoint of boxing, that of knee joint of skating, that of intertasal joint of hand ball, and

酵母細胞의 인산대사 및 유기물 합성에 미치는 무기인산 화합물의 영향

崔榮吉,이기성,李鍾三,趙善姬 漢陽大學校 環境科學硏究所 1983 環境科學論文集 Vol.4 No.-

효모의 개체군 생장에 미치는 인산 화합물(??) 및 ??, ?? 양이온의 영향을 측정한 결과, ??는 Knopp씨 배지수준의 1배, 10배, 50배 처리의 전구간에 걸쳐서 개체군 생장에 유의한 촉진효과를 볼 수 없었다. ?? 처리구에서는, ?? 의 1배 처리구에서 대조구에 비하여 뚜렷한 생장촉진효과를 볼 수 있었으나, 10배, 50배의 처리구에서는 오히려 생장이 감소함을 나타내었다. 또한 ?? 처리구는 전 구간에 걸쳐서 대조구에 비하여 뚜렷한 억제가 관찰되었다. 한편, 효모의 인산화합물 합성에 미치는 영향을 측정하여 본 결과, ??의 경우는 산 가용성 Total-P 가 전 구간에 걸쳐 배양 처리후 6일째에, 대조구에 비하여 증가하였으며, ??처리구는 전처리구에서 산가용성 Total-P가 감소하였으나 ortho-P만은 증가하였음을 보였다. ??의 처리구에서도 Total-P는 역시 대조구에 비하여 감소하고 ortho-P는 대조구와 비슷한 경향을 보였다. poly-P "A", "B", "C", type 의 소장 관계를 측정한 결과, poly-p-A 와 B는 인산농도 및 양이온의 농도가 높을수록 많은 생성량을 나타내었으며, 특히 ?? ×50 처리구에서 poly-p-"B" 의 최대 합성량을 볼 수 있었다. 또한 여러 배양조건하에서도, 여러가지 poly-P 전환과정은 모든 시험구에서 동일한 것으로 나타났다. 그리고 특히 ?? 이온에 의해 영향받는 poly-P의 유기물합성에 이용되는 전환경로와 poly-P 상호 전환경로는 다음의 관계가 성립하는 것으로 추론된다. ?? 한편, 효모세포의 단백질, 핵산, 인지질, 탄수화물 합성에 미치는, 이들 인산 화합물의 양적 동태를 고찰한 결과, 핵산의 경우, ?? 처리구는 모든 구간에서 핵산 합성에 유의한 효과를 찾을 수 없었으며, ??처리구는 1배농도의 처리구에서는, 핵산의 합성증가를, 그외의 처리구에서는 합성량이 낮았다. ?? 처리구에서는 전체적으로 현저한 유기물의 합성억제를 나타내었다. 단백질 합성의 경우는 ??×1처리구를 제외한 모든 처리구에서 대조구와 비교하여 비슷한 경향을 나타내거나 억제효과를 보여주었을 뿐,촉진효과를 관찰할 수 없었다. 인지질 합성시 ??는 촉진효과를 나타내었으나 ?? 와 ?? 는 유의한 효과를 볼 수 없었다. 효모의 탄수화물 합성에 있어 ?? 는 대체로 대조구의 합성량과 유사하며, ?? 의 경우와 ??의 경우는 전 처리구간에서 대조구에 비하여 배양초기에 억제효과를 나타내었으나, 배양후기에는 오히려 증가되었다. 한편 poly-P와 유기물 합성과의 상관관계에서, Polysaccharide,lipid-p, DNA 합성에는 Poly-P-B가, nucleotidic-labile-P 생성에는 poly-P-C 가 상호 연관된 것으로 추정되었다. Examined the effect on the growth of yeast population by treating medium with phosphate compounds such as ??, ?? and ?? ion as the the concentration of Knopp's level, tenfold concentration and of fiftyfold, respectively, it could be recognized as the following facts; in case of ??, it showed no significant effect on the growth of yeast population in all treatmemt. And in case of ?? treatment replaced K? of KH₂PO₄in knopp's medium it showed the stimulating effect in the culture as comparing with those of control, but on the contrary, it was revealed the inhibition effect in the culture of tenfold and fifty fold treatment. However, the addition of ?? compounds showed the clear evidence of inhibition effect in population growth. Measuring the effect on the synthesis of phosphate compounds of yeast cell by treating the above chemicals, the amount of acid soluble-total phosphate was increased in all ?? teatment on 6th day after treatment. On the contraty, in case of ?? treatment, the amount of acid soluble-total phosphate was decreased in all treatment comparing with that of control, but the amount of ortho-phosphste was increased in all cultures. These similar tendencies were also found in the cultures of As?? compound treatment. The amount of acid soluble-total phosphate was decresed comparing with that of control and ortho-phosphate was as of control level. The accumulation amount of each type of polyphosphate(A,B and C) seemed to have a relationship between each other. It seemed that the amounts of polyphosphate A and B in yeast cell are increased in accordance with high cation concentration and phosphate concentration in culture medium. Especially, the culture in fiftyfold concentration of ?? ion synthesized the highest amount of polyphosphate B. However, the trun-over patterns of each polyphosphate under various conditions showed similar tendencies with each other. But the patterns utilizing in synthesis of cellular organic matter are belived to be affected by ?? ion as the direction in the following figure. ?? The synthesis of cellular organic matter, such as protein, nucleic acid, phospholipid , and polysaccharide was also belived to have a relation to cellular nutritional conditions. Any treatment of ?? showed no significant effect in synthesis of nucleic acid . The treatment of ?? compounds was resulted in decreased of nucleic acid generally, but increase in the culture replaced ?? of KH₂PO₄of Knopp's medium by ??. However, all the treatment of ??) compounds to medium showed strong inbibition effect in synthesis of nucleic acid. The synthesis of cellular protein is promoted by treating ?? compounds as Knopp's level. but in case of tenfold and fiftyfold concentration, the amount of protein is equivalent to or below to that of control. Referring to synthesis of phospholipid, ?? treatment was effective, but ?? and ?? compounds showed inbibition effect. The amount of carbohydrate in yeast cell treated by ?? is similar to those of control, however, in the cell treated by ?? or ?? compounds, the amount was increased just after decreasing in early stages of incubation. The relationship between each polyphosphate and synthesis of cellular organic matter could be interpretated that polyphosphate B is utilized mainly in synthesis of polysaccharide, phospholipid and DNA, and that polyphosphate C is also related in formation of nucleotidic labile phosphate.

1~2기 본태성 고혈압 환자들에서 Imidapril 대 Enalapril의 항고혈압 효과를 평가하기 위한 무작위, 이중맹검 임상시험

최영진,손대원,김용진,이홍자,채인호,김효수,김철호,오병희,이명묵,박영배,채윤식,이영우 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.11

마르크스主義 社會正義論에 關한批判的 硏究

최일성,홍용희,노병철 忠州大學校 2003 한국교통대학교 논문집 Vol.38 No.1

This dissertation attempts to examine the theories of social justice in Marxism. The Marxist critique of justice requires us to raise the issue of whether justice has a distinctive meaning beyond conformity to established rules and practices and, if so, if this can be distinguished from and related to other social and political ideals. Marx's contention is that rights and justice are essentially bourgeois ideas which impress the ideology of capitalist economic organization. If justice is indeed an intrinsically capitalist concept, then it is predictable that those who propound a normative theory of justice will express the values of bourgeois individualism. There is a good deal of textual evidence for Marx's theoretical amoralism and his anti-justice and anti-rights stances. Certainly Marx did not think that juridical concepts like justice have any significant role to play in the explanation of social structure and social change. Nevertheless Marx's radically different starting-point implies that a socialist theory of justice must differ from liberal theories not only in the content of its principles but also in the function which it allots to justice discourse. Marx rejected Mill's choice criterion of value and Rawls' conception of deliberative rationality as individualistic abstractions. Especially the concept of exploitation plays a key role in Marx's attack on capitalism. Marx's views on justice and rights rejected the idea that juridical conceptions are the most fundamental conceptions for explaining social phenomena. This rejection of the juridical model is, of course, an inference from Marx's materialist views on the relation between the base and the superstructure of a given society. Marx concludes that juridical conceptions of justice and rights play neither a major explanatory nor a major critical role. Marx is committed to a very radical position on the state and social justice. We argue that this radical evaluative perspective is more epistemological than moral in any traditional sence.

CRP* 의존성 maltose 대사 촉진 유전자 sfs4의 클로닝 및 염기배열 결정

최용락,정희태,조무제,정수열 東亞大學校附設遺傳工學硏究所 1996 遺傳工學硏究 Vol.- No.3

CRP (cAMP receptor protein)은 cAMP와 결합하여 cAMP-CRP 복합체를 형성하여 전사조절의 조절인자로서 작용한다. crp 유전자에 변이를 도입하여 cAMP의 비존재 상태에서 cAMP-CRP와 비슷한 기능을 가진 crp* 유전자가 도입된 대장균 MK2001 (crp*¹, cya::km)을 숙주로 사용하여 cAMP 혹은 cGMP의 비존재하에서도 mal 유전자의 발현을 촉진시키는 유전자 sfs (sugar fermentation stimulation) 수 종을 클로닝하였다. 본 실험에서는 이미 밝혀진 nlp (Ner like protein) 유전자와 같이, sfs의 새로운 유전자를 탐색하여, 그 중 sfs4의 2126bp 전 염기배열을 결정하고, 잠정적인 sfs4의 promoter 영역에는 CRP 단백질과의 결합 DNA 공통 염기배열(5' AAT TGTGA ACACCA TCACC CGT 3')이 존재함을 확인했다. lacZ 융합 유전자를 작성하여 TP2010R1과 MK2001의 균주에서 cAMP를 첨가할 경우 각각 2.3배, 1.8배의 β-galactosidase 활성이 증가 하는 것으로 보아 sfs4는 cAMP-CRP에 의해 발현 조절을 받는 것으로 나타났다 In Escherichia coli, CRP forms a complex with cAMP and acts as a transcriptional regulator of many genes, including sugar metabolism operons. The E. coli MK2001, which is introduced the altered crp*¹, is functional in the expression of lac, ara and man, in the absence of cAMP. However, the expression of mal gene is fully activated by the addition of cAMP or cGMP. The object of the study is cloning of the sfs (sugar fermentation stimulation) genes, which was involved in regulation of mal gene expression with the altered crp*¹gene, and structural analysis and characterization of the genes at the molecular level. We have cloned 5 different E. coli genes which stimulate the maltose metabolism in a crp*¹, cya::km (MK2001) background. Newly identified genes were designated as sfs. One of the sfs genes (pPC1), located at the 53.2 min map position in the E. coli chromosome, was further analyzed. Expression of the genes, which is involved in maltose metabolism, malQ (amylomaltase), was increased to 5.8-fold in the presence of a plasmid, pAP5, containing the subcloned sfs4 gene. The nucleotide sequence of a common 2,126bp segment of the pPCM1 was determined and two open reading frames (ORF1 and ORF2) were detected. The ORF1 encodes the sfs4 gene and ORF2 encodes a truncated protein. Potential CRP binding site is located in the upstream of the putative promoter in the regulatory region. Expression of the cloned sfs4 gene was positively regulated by the cAMP-CRP complex.

팥의 RAPD 분석 조건 최적화 연구

이충열,박현철,박진철,김성만,김용철,최재희,최인수 밀양대학교 농업기술개발연구소 2000 農業技術開發硏究所報 Vol.4 No.1

The object of this study was to optimize PCR condition for RAPD analysis in adzuki bean. The best template DNA concentration was 20ng(0.25unit taq polymerase and 2.5mM MgCl2), 40ng(1unit taq polymerase and 2.5mM MgCl2, 1unit taq polymerase and 4.5mM MgCl2 and lunit taq polymerase and 7.0mM MgCl2), and 60ng(0.5unit taq polymerase and 2.5mM MgCl2, 0.5unit taq polymerase and 4.5mM MgCl2, 1unit taq polymerase and 2.5mM MgCl2, and 1unit taq polymerase and 4.5mM MgCl2) The best MgCl2 concentration was 2.5mM(40ng template DNA and 1unit taq polymerase, 60ng template DNA and 0.5unit taq polymerase, and 60ng template DNA and 1unit taq polymerase), 4.5mM(20ng template DNA and 0.25unit taq polymerase, 60ng template DNA and 0.5unit taq polymerase, and 60ng template DNA and 1unit taq polymerase), and 7.0mM(40ng template DNA and 1unit taq polymerase). Amount of taq polymerase was 0.25unit(20ng template DNA and 2.5mM MgCl2), 0.5unit(60ng template DNA and 2.5mM MgCl2, 60ng template DNA and 4.5mM MgCl2) and 1unit(40ng template DNA and 2.5mM MgCl2, 40ng template DNA and 4.5mM MgCl2, 40ng template DNA and 7.0mM MgCl2, 60ng template DNA and 2.5mM MgCl2, 60ng template DNA and 4.5mM MgCl2, and 60ng template DNA and 7.0mM MgCl2). When we consider results from template DNA concentration, MgCl2 concentration, and amount of taq polymerase, the best condition for PCR optimization was 60ng template DNA, 4.5mM MgCl2, and 1unit taq polymerase. Reaction temperatures for the optimal PCR condition were 84℃, 32℃, 62℃; 90℃, 40℃, 72℃; and 92℃, 36℃, 72℃.