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      • 혈중 및 호기 일산화탄소를 이용한 일산화탄소 헤모글로빈 농도간의 관련성 연구

        김형수,박태혁,손지언,정갑열,김정만,김준연 동아대학교 2001 大學院論文集 Vol.26 No.-

        This study was conducted to find a correlation between blood COHb and calculated COHb with expiratory air and related variables such as occupational and smoking factors. Author selected 69 healthy workers in 8 workplaces suspected CO exposure. Basic informations were collected by self-reported questionnaire and medical history taking. Author measured Indirect COHb concentration with expiratory air using Micro II-Smokerlyzer and blood COHb concentration using Oxymeter. The results of the study were summarized as follows : 1. In the smoker, mean blood COHb and calculated COHb with expiratory air were 2.21±0.98% and 2.27±0.97 %, and there was not a statistically significant difference. In the non-smoker, mean blood COHb and calculated COHb with expiratory air were 0.42±0.43 % and 0,65±0.30 %, and there was also not a statistically significant difference. 2. There were positive correlations between blood COHb and calculated COHb with expiratory air in both the smoker (r=0.91, p=0.0001) and non-smoker (r=0.73, p=0.0001). 3. In the smoker, the factors affected COHb were total smoking index (Pack × years) and passed time after the last smoking. 4. In the nonsmoker, the parking and driving groups had higher COHb concentration than others (p<0.05). In conclusion, there was no significant difference between indirect COHb concentration with expiratory air using Smokerlyzer and blood COHb concentration and there was a highly significant correlation between indirect and blood COHb concentrations. Therefore indirect COHb concentration with expiratory air is a useful screening method for CO exposure. Author suggest the resection of smoking during at least 90 minutes before measuring COHb concentration in order to exclude smoking effects.

      • KCI등재후보

        개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예

        윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

        A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.

      • 제2형 당뇨병 환자의 치료에서 복약순응도가 혈당 조절에 미치는 영향

        김경선,김민정,박소현,박영주,허정순,이은경,김선영,이수형,김상수,강양호,손석만,김인주,김용기 한국병원약사회 2009 병원약사회지 Vol.26 No.2

        Abstract: As known in clinical trial like DCCT, UKPDS, tight glycemic control is essential to prevent complications from diabetes mellitus(DM). In type 2 diabetes taking multiple medication, nonadherence to medications is common problem. The aim of our study is to investigate adher-ence rate of patients with type 2 DM and to evaluate association between many factors including adherence rate and HbA_(1C). 441 patients with type 2 DM who visited Busan National University Hospital endocrine internal department from Aug 13 to Sep 2, 2008(3weeks) were enrolled. We conducted a man-to-man questionnaire survey about general knowledge about diabetes mellitus, medicine and adherence, and measured HbA_(1C). Among them, 305 patients taking oral hypo-glycemic agent(OHA) were analyzed to investigate correlation between adherence rate and glycemic control. We studied 305 patients(male 126, female 179, average age 61.2±9.8 years, DM duration 8.6±6.4 years, average adherence 88.8±16.2%, average HbA_(1C) 7.03± 1.18%). HbA_(1C) showed significant relation with DM duration(r=0.137, p=0.017), number of aHA in regimen (r=0.135, p=0.018), dosage frequency(r=0.132, p=0.026), Medication Refill Adherence(MRA)(r=-0.124, p=0.030) and adherence(r=-0.168, p=0.003). Adherence had significant relation with MRA(r=0.148, p=0.010) but didn't have statical corelationship with DM duration, number of aHA and dosage frequency. Patients that their adherence rate exceed 90% took fewer OHA(p=0.011) and went on a better dietary treatment(p=0.007). In patients controlling diabetes mellitus with aHA, when adherence rate and MRA was higher, HbA_(1C) was lower. As a result, to improve adher-ence rate, it is necessary to enhance patient education, do careful consideration about prescrip-tion medicine number and dosage frequency

      • SCIESCOPUSKCI등재

        자궁경부에 발생한 배아성 횡문근육종 2예

        박정열,조준식,김대연,이동헌,김종혁,김용만,김영탁,목정은,남주현 대한부인종양 콜포스코피학회 2002 Journal of Gynecologic Oncology Vol.13 No.3

        횡문근육종은 소아와 청소년기에 가장 흔한 연부조직 육종이다. 발생 부위는 일반적으로 두부 및 경부, 그 다음으로 비뇨생식계이다 조직학적으로 배아성 횡문근육종, 국화상 육종, 폐포성 횡문근육종, 다형성 횡문근육종으로 나누어진다. 횡문근육종의 약 20%가 비뇨생식기에서 발생하고, 50% 이상이 배아성 횡문근육종이다. 여성 생식기의 배아성 횡문근육종은 드문 악성 종양으로,주로 유소아의 질에서 발생하며, 자궁경부에서 발생하는 횡문근육종은 청소년기에 흔하고, 질에서 기원하는 횡문근육종이 자궁경부에 기원하는 경우보다 5배 정도 많다. 폐경기여성에서는 자궁체부에서 가장 흔히 발생한다. 비뇨생식기의 횡문근육종의 치료는 과거에는 골반장기 적출술만으로 치료를 시도하였으나. 서서히 다중 항암화학요법, 방사선요법, 근치적 절제술을 포함한 병합요법으로 바뀌어가고 있으며, 이에 따라 생존율이 현저하게 향상되었다. 이에 저자들은 최근 본원 산부인과에서 자궁경부에 발생한 배아성 횡문근육종 2예를 경험하였기에 문헌 고찰과 아울러 보고하는 바이다. Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and young adult. Genitourinary tract is the econd most common site of rhabdomyosarcoma. Rhabdomyosarcoma can be classified into one of four major types; embryonal, alveolar, pleomorphic and undifferentiated. Embryonal rhabdomyosarcoma of the female genital tract is rare malignant tumor and usually occurs during childhood in the vagina. In rare cases, rhabdomyosarcoma can originate in the uterine cervix, with a peak incidence in the second decade. Recently we have experienced two cases of embryonal rhabdomyosarcoma of the uterine cervix. These cases are presented with a brief review of the literature.

      • KCI등재
      • KCI등재

        동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

        박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

        This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

      • InStep^(TM) DfE를 이용한 에코디자인 수행사례 : Applying InStepTM DfE

        박인성,정정만,이한경,김선영 한국전과정평가학회 2004 한국전과정평가학회지 Vol.5 No.1

        개인용 컴퓨터를 대상으로 설계자용 에코디자인 소프트웨어인 InStep^(TM) DfE를 이용하여, 에코디자인을 수행한 사례를 제공한다. 에코디자인을 위하여 우선, 기준제품의 환경성을 유해물질, 재활용성, 분해성, 자원고갈, 에너지효율성, 5가지의 환경측면에 초점을 맞추어 평가하였다. 그리고 평가결과를 역추적하여 취약한 환경측면과 그 원인 부품을 규명하고 이를 개선하기 위한 대안을 개발하였다. 대안은 [납의 제거]와 [100% 재활용된 ABS사용], [ABS를 PVC로 교체] 3가지였으며, 개발된 대안과 기준제품의 환경성을 비교평가하여 최적의 에코디자인 대안을 선정하였다. Ecodesign for personal computer by applying InStep^(TM) DfE, which is a web based ecodesign software for designer, conducted in this study. In first, environmental assessment of reference product focusing on five ecodesign strategy(hazardous substance, recyclability, disassembly, resource consumption, energy efficiency) is performed. Then, identifying environmentally weak point of reference product and developing alternatives to improve it's weakness is processed. Three alternatives is considered that 'lead-free soldering', 'replacing virgin ABS to 100% recycled ABS', 'replacing ABS to PVC'. And finally, environmental comparative assessment between alternatives and reference product is preformed to determine best product design.

      • 韓國産 싸리屬의 形態學的 硏究

        朴鍾烈,金鍾萬,朴正德 慶尙大學校 1972 論文集 Vol.11 No.-

        우리나라에 널리 자라고 있는 지피조성용, 사료, 밀원, 공예, 섬유, 관상자원으로서 중요한 싸리속 식물의 몇가지 특성을 관찰하여 그의 분류상의 식별점을 조사 하였다. 본실험을 통하여 구명된 결과를 요약하면 다음 검색표와 같다. 1. 花粉의 型은 3-colporate 6B??, 小網狀紋이며 크기가 20μ이상 이다…2 1. 花粉의 型은 3-colporate 6B??, 小網狀紋이며 크기가 20μ이하 이다…6 2. 잎은 녹색이다.…3 2. 잎은 농록색이다…4 3. 꽃은 홍자색이고 크기는 S>K>W, 꼬투리는 表面에 有毛, 망맥이 있으며 난상타원형이고 뿌리의 색깔은 흑색이다.…Lespedeza bicolor Turcz(싸리) 3. 꽃은 赤紫色이고 크기는 S>W>K, 꼬투리는 表面에 有毛, 망맥이 있으며 타원형이고 뿌리의 색깔은 黑紫色이다.…Lespedeza bicolor var. melanantha(Nakai) T. Lee(쇠싸리) 4. 꽃의 크기는 S>K>W의 순이다…5 4. 꽃의 크기는 S>W>K의 순서이고 꼬투리는 난형이고 表面에는 털이 있고 망맥이 있으며 뿌리의 색깔은 황색이다.…Lespedeza cyrtoborya Miq.(참싸리) 5. 꼬투리는 광란형이고 암갈색이며 表面에 有毛이고 뿌리의 색깔은 흰색이다.…Lespedeza cuneata G. Don(비수리) 5. 꼬투리는 난상타원형, 담갈색, 表面에 有毛, 망맥이 있으며 뿌리의 색깔은 적색이다…Lespedeza japonica var. intermedia Nakai(풀싸리) 6. 뿌리의 색갈은 Yellowish white 이며 꼬투리는 장타원형으로서 꽃의 크기가 K>W>S의 순서로 된다…7 6. 뿌리의 색깔은 yellowish white 이며 꼬투리는 광타원형, 꽃의 크기가 S>K>W의 순서이다…Lespedaez maximowicxii Schneider(조록싸리) 7. 小化梗의 길이가 1.17∼1.97mm이고 종자는 신장형으로 황록색이고 반점이 없다…Lespedeza maximowiczii var. tomentella Nakai(털조록싸리) 7. 小化梗의 길이가 2.43∼2.79mm이고 종자는 신장형으로 암갈색이고 반점이 있다…Lespedeza maximowiczii var. tricolor Nakai(삼색싸리) It was intended to identify the members of the Genus Lespedeza in Korea by the investigation of morphologycal characteristics, i.e., leaf length and width, stomata size and density, flower size, pod type and colour, seed type and colour, pedicel length and root colour. The following 5 species were used in this experiment. ① Lespedeza bicolor Turcz ② Lespedeza bicolor var. melanantha(Nakai) T. Lee ③ Lespedeza cuneata G. Don ④ Lespedeza cyrtobolrya Miq. ⑤ Lespedeza japonica var. intermedia Nakai ⑥ Lespedeza maximowiczii Schneider ⑦ Lespedeza maximowiczii var. tomentella Nakai ⑧ Lespedeza maximowiczii var. tricolor Nakai The results can be summarized as the following key; 1. Pollen type of 3-colpolate 6B??, subre; pollen size larger than 20 microns…2 1. Pollen type of 3-colpolate 6B??, subre; pollen size less than 20 microns…6 2. Leaves green colour…3 2. Leaves deep green colour…4 3. Flower size standard> keel> wing, reddish purple;pods shaped ovate-elliptic, pubescent, the reticulum faint; roots dark colour… Lespedeza bicolor Turcz 3. Flower size standard> wing> keel, red purple; pods elliptic, pubescent, the reticulum faint; roots dark purple…Lespedeza bicotor var. melanantha(Nakai)T. Lee 4. Flower size standard> keel> wing…5 4. Flower size standard> wing> keel; pods ovate, pubescent, the reticulum faint; roots' yellow…Lerpedeza cyrfobotrya Miq. 5. Pods broadly ovate, dark reddish brown, pubezcent across the top and along the sides; roots white…Lespedeza cuneata G. Don 5. Pods pilous ovate-elliptic, light bown, pubescent, the reticulum faint; roots red…Lespedeza japonica var. intermedia Nakai 6. Roots yellowish white; pods oblong; flower size keel> wing> standard…7 6. Roots yellowish white; pods broadly elliptic; flower size standard>keel>wing…Lespedeza maximowiczii Schneider 7. Pedicels 1.17mm.∼1.93mm. length; seeds kindney shaped, yellowish grenn.…Lespedeza maximowiczii var. tomentella Nakai 7. Pedicels 2.43∼2.79mm. length; seeds kidney shaped, dark brown spots on the greenish brown coat…Lespedeza maximowiczii var. tricolor Nakai

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