야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

In vitro Mammalian Chromosomal Aberration Test of Fullerene-C60

Soo Jin Kim(김수진),Kyung Taek Rim(임경택),Hae Won Cho(조해원),Jeong Hee Han(한정희),Hyeon Yeong Kim(김현영),Jeong Sun Yang(양정선) 환경독성보건학회 2009 환경독성보건학회지 Vol.24 No.1

Fullerene의 유전독성을 평가하기 위하여 Chinese hamster유래의 난소유아세포(CHO-K1 cell)를 이용하여 직접법(-S9)과 대사활성화법(+S9 mix)의 염색체이상시험을 실시하였다. 시험물질은 1% CMC 나트륨염의 현탁액(l% CMC 용액)에 희석하여 조제하였다. 대사활성화를 시키지 않은 직접법의 염색체이상시험에서 24시간 투여군은 8단계의 농도(0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)로 투여하여 실시하였다. 투여 농도 증가에 따른 염색체이상의 빈도가 증가하는 양상이 나타나지 않았다. 48시간의 투여군에서는 8단계의 농도(0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)로 투여하여 실시하였는데 투여 농도 증가에 따른 염색체이상의 빈도가 증가하는 양상이 나타나지 않았다. 배수체의 염색체이상은 직접법에서 관찰되지 않았다. 대사활성화법을 이용하여 6시간 시험물질을 투여한 시험에 있어서는 8단계의 용량단계 (0.078, 0.156, 0.313, 0.625, 1.25, 2.5, 5, 10mM)를 설정하였는데 투여 농도가 증가함에 따른 염색체이상빈도의 증가양상이 관찰되지 않았다. 이상의 결과를 종합할 때 본 시험물질은 본 시험 조건하에서 CHO-K1세포에서 대사활성화를 시켰을 때 염색체 이상을 유발하지 않는 것으로 판단된다.

산업자본재 자산의 가치평가에 있어 신뢰도 함수의 적용

조진형,이도경,김상호 금오공과대학교 산업기술개발연구원 2001 産業技術開發硏究 Vol.17 No.-

Box-Cox model by HuIten and Wykoff and T-factor method by Elfar and Whelan, adopted the assumptions of the characteristics of capital assets, and are still widely used today even though their assumptions were weak. We improve the Box-Cox model by combining the existing economic efficiency and depreciation pattern, based on the efficiency curve of marginal productivity and reliability function. Thus, Rayleigh curve which has been used for the reliability of current capital assets was chosen as m efficiency curve. As a result, it was possible to classify the efficiency curves into 4 kinds rather than the existing 3, as well as the types of depreciation curves. In this paper, therefore, the power family of the Box-Cox model which was a non-linear regression model would be identified, by utilizing the reliability functions. In addition, Box-Cox model as a linear model to measure economic depredations. Based on these result it is easy to estimate economic depreciations as well as to test depreciation rates.

The Influence of AH-26 and Zinc Oxide-Eugenol Root Canal Sealer on the Shear Bond Strength of Composite Resin to Dentin

Cho, Ju-Yeon,Jin, Myoung-Uk,Kim, Young-Kyung,Kim, Sung Kyo 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.3

AH-26 근관실러가 상아질에 대한 복합레진의 전단결합강도에 미치는 영향을 평가하기 위하여 144개의 발거된 대구치를 실린더형의 몰드에 매식한 다음 치관부의 상아질 표면을 노출시킨 후 편평하게 연마하고 AH-26을 도포한 군, ZOE paste를 도포한 군 및 실러를 도포하지 않은 대조군으로 나누어 One-step 상아질 접착제를 처리한 후에 Charisma (Heraeus Kulzer, Germany) 복합레진을 적용하고 광중합시켰다. 시편을 분리하여 37℃ 항온조에 24시간 보관후 Instron test machine (Model 4202, Instron Corp., USA)을 이용하여 시편의 전단 결합 강도를 측정하고 one-way ANOVA 및 Tukey's studentized rank test로 통계 분석하였다. AH-26 근관실러로 처리한 군과 대조군은 ZOE 근관실러 처리군에 비해 유의하게 놓은 접착강도를 나타내었다 (p<0.05). AH-26 근관실러 처리군과 아무 처리하지 않은 대조군 사이에는 결합강도에 있어 유의한 차이를 나타내지 않았다 (p>0.05). 본 연구의 조건에서는 ZOE 근관실러는 상아질에 대한 복합레진의 전단결합강도를 저하시키는 반면 AH-26 근관실러는 유의한 영향을 미치지는 않는 것으로 보인다. 따라서 임상에서 근관실러로 AH-26을 사용한 근관충전 후에는 즉시 복합레진 코어를 해 주어도 결합력에 저해가 없을 것으로 여겨진다. The purpose of this study was to evaluate the influence of the AH-26 root canal sealer on the shear bond strength of composite resin to dentin. One hundred and forty four (144) extracted, sound human molars were used. After embedding in a cylindrical mold, the occlusal part of the anatomical crown was cut away and trimmed in order to create a flat dentin surface. The teeth were randomly divided into three groups; the AH-26 sealer was applied to the AH-26 group, and zinc-oxide eugenol (ZOE) paste was applied to the ZOE group. The dentin surface of the control group did not receive any sealer. A mount jig was placed against the surface of the teeth and the One-step dentin bonding agent was applied after acid etching. Charisma composite resin was packed into the mold and light cured. After polymerization, the alignment tube and mold were removed and the specimens were placed in distilled water at 37℃ for twenty four hours. The shear bond strength was measured by an Instron testing machine. The data for each group were subjected to one-way ANOVA and Tukey's studentized rank test so as to make comparisons between the groups. The AH-26 group and the control group showed significantly higher shear bond strength than the ZOE group (p<0.05). There were no significant differences between the AH-26 group and the control one (p>0.05). Under the conditions of this study, the AH-26 root canal sealer did not seem to affect the shear bond strength of the composite resin to dentin while the ZOE sealer did. Therefore, there may be no decrease in bond strength when the composite resin core is built up immediately after a canal filling with AH-26 as a root canal sealer.

2.5-헥산디온에 노출된 근로자에게서 발생한 말초 신경병증

조성용,장용석,최은경,김진석,유재영,우극현,최태성 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.1

목적: 영상음향장비 제조업체에서 2,5-헥산디온을 취급한 근로자에게서 발생한 다발성 말초 신경병증 환례를 보고하고, 동일 공정근로자들의 말초 신경기능을 조사하고 자 한다. 방법: 환례에 대해 방사선학적 검사, 소변 및 혈액 검사, 신경전달속도 검사, 작업환경 측정을 하였으며, 2,5-헥산디온의 노출을 중단시킨 후 5개월 후에 다시 신경전달속도 검사를 하였다. 동일공정 근로자들의 영향평가에서는 2,5-헥산디온에 노출된 13명의 남자 근로자를 노출 군으로, 해당 물질에 노출된 적이 없는 5명의 남자 근로자를 비노출군으로 선정하여 검사를 하였다. 결과: 환례의 신경전도 검사결과 양측 척골신경과 정중 신경에 이상소견을 보였으며, 호전여부를 관찰하기 위하여 5개월 후 추적검사를 실시한 결과 증상 및 신경전달속도 검사결과가 호전되었다. 동일공정 근로자들의 영향평가에서 노출군의 정중 신경과 척골신경이 비노출군에 비하여 유의하게 감소되어 있었다. 감각 신경의 진폭의 경우, 노출군의 정중 신경과 비복 신경이 감소되었으며, 운동 신경 전도속도에서는 노출군의 비골신경이 유의하게 감소되어 있었다. 말단 잠복기에서는 노출군의 정중신경, 척골신경, 비골신경, 경골신경이 비노출군에 비해서 유의하게 연장되어 있었다. 결론: 환례의 증상과 신경전달속도 검사의 이상소견은 2,5-헥산디온에 의한 말초신경병증에 부합되었다. 동일공정 근로자 건강영향평가에서 신경전달속도 검사결과 노출 군과 비노출군간의 유의한 차이가 있었는데, 이를 통해 2,5-헥산디온이 근로자들의 신경독성에 영향을 줄 수 있다는 것을 확인할 수가 있었다. Objectives: This study is a case report of 2,5-hexanedione induced occupational peripheral polyneuropathy. We also investigated the peripheral nerve function of all workers who had been exposed to 2,5-hexanedione in the same process. Methods: In June, 2006, a 2,5-hexanedione exposed worker complained of both hand numbness. He received neurologic, radiologic, laboratorial and electrophysiologic evaluation, including measurements of workplace environment. Five months after cessation of exposure to 2,5-hexanedione, a follow-up electrophysiologic examination was done. We evaluated the peripheral nerve function of 2,5-hexanedione exposed workers by comparing 13 male 2,5-hexanedione exposed workers who were in same company with the patient and 5 male workers who had not been exposed to 2,5-hexanedione. Results: Under electrophysiologic examination, there were abnormalities in sensory and motor nerve velocity, terminal latency, and F-latency of both median nerve and ulnar nerve. After 5 months, the patient symptoms and the results of follow-up electrophysiologic examinations were improved. Comparing the 2,5-hexanedione exposed group with the unexposed group, the sensory nerve velocity of the median and ulnar nerves in the exposed group was decreased. The motor nerve velocity of the peroneal nerve, and sensory nerve velocity of the median and sural nerves were decreased. Terminal latency of median, ulnar, peroneal, and tibial nerves in the exposed group were increased compared with the unexposed group(<0.05). Conclusions: 2.5-hexandione can induce peripheral polyneuropathy in male workers.

누구를 위한 POCT인가?

조경진,이창규,이승관,정희천,김미숙,남경미,전주임 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Patient-oriented minds and Bill of Rights have brought a lot of POCTs or Waived Tests, which can obviously be threats to the medical technology profession. However, we cannot help but admit the realities and should take some necessary measures to meet the situation. Accordingly we took a survey to find what opinions medical scientists or nurses have against the POCTs. Most of the scientists worried about the reliabilites of test results while nurses were concerned about the ambiguity of their job entities. Taking account of the POCT nature, the scientists should lead the development of POCT menus and have the primanry responsibility to educate or train the POCT perfomers maitaining periodic QCs on all the procedures or equimpments, not paying much attention to the issues who might be the performers.

길안천(경북 안동)의 저서성대형무척추동물 군집변동 및 생물학적 수질평가

조희욱,김경호,노상은,박진영,서을원,이종은 7개 국립대학교 환경연구 논문집 공동발행 위원회 2004 공업기술연구 Vol.4 No.-

A biological assessment of water quality was carried out in Giran stream from May 203 to January 2004. The benthic macroinvertebrates collected seasonally from 5 field sites were identified mostly up to species level. The benthic macroinvertebrates collected from the surveyed sites were composed of 88 species, 68 genera,42 families, 14 orders, 5 class and 4 phyla. The dominance index (DI) showed the high-est as 0.802 at site 5 and the lowest as 1.643 at site 3. Ecological score of benthic macroinvertebrate (ESB) showed the highest as 103 at site 2 and the lowest as 63 at site 3. All surveyed sites were Oligosaprobic that the water quality estimated by ecological score of benthic macroinvertebratc community.

전자의무기록의 충실성 검토를 통한 미비기록 개선 활동

조윤정,김경숙,이향숙,이진영,김태민,김민순 한국의료QA학회 2008 한국의료질향상학회지 Vol.14 No.1

문제: 전자의무기록(EMR) 시행 후 의무기록 정리율의 저하와 질적인 측면에서의 충실성과 정확성에 대한 문제점이제기되었다. 목적: 전자의무기록의 정리율과 충실성 검토를 통하여 문제점을 파악하고개선점 찾아 의무기록 정리율을 향상시키고 충실성을 높이고자 하였다. 의료기관: 서울시에 소재한대학병원 의무기록과 질 향상 활동: 전자의무기록의 문제점을 개선히키 위하여 사용자 편의를 위한 EMR프로그램 수정 및 보완, 진단·수술 관련 작업, 업무개선, 교육, 홍보 등의 활동을실시하였다. 개선효과: 의무기록 정리율, 전자인증미비, 경과기록 기재일수, 퇴원요약주진단적합률, 기록지별 필수항목기 재율, 충실성에서 향상이 이루어졌다.

일기상자료에 의한 읍면별 벼 작황진단 및 쌀 생산량 예측

조경숙,윤진일 한국농림기상학회 1999 한국농림기상학회지 Vol.1 No.1

CERES - rice, a rice growth simulation model, was used in conjunction with daily weather data to figure out the spatial variation of the phenology and yields of paddy rice at 168 rice cultivation zone units(CZU) of Kyunggi Province in 1997. Two sets of cultivar specific coefficients, which represent early and mid - season maturing varieties, were derived from field experiments conducted at two crop experiment stations. The minimum data set to run the model for each CZU (daily maximum and minimum temperature, solar irradiance, and rainfall) was obtained by spatial averaging of existing "Digital Map of Korean Climate"(Shin et al., 1999). Soil characteristics and management information at each CZU were available from the Rural Development Administration. According to a preliminary test using 5 to 9 years field data, trends of the phasic development (heading and physiological maturity ), which were obtained from the model adjusted for these coefficients, were in good agreement with the observed data. However, the simulated inter - annual variation was somewhat greater than the reported variation. Rough rice yields of the early maturing cultivar calculated by the model were comparable with the reported data in terms of both absolute value and inter - annual variation. But those of the mid season cultivar showed over estimation. After running the simulation model runs with 1997 weather data for 168 CZU's, rough rice yields of the 168 CZU's calculated by the model were aggregated into corresponding 33 counties by acreage - weighting to facilitate direct comparison with the reported statistics from the Ministry of Agriculture and Forestry. The simulation results were good at 22 out of the 26 counties with reportedly increasing yield trend with respect to the past 9 years average.

서방형 Diltiazem제제의 개발을 위한 약동학/약력학적 특성 검토

유경상,배균섭,조주연,장인진,신상구 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2