한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

유아의 기질과 기초체력과의 관계

진행미 ( Haeng Mi Jin ),고영주 ( Young Joo Koh ) 한국유아체육학회 2008 한국유아체육학회지 Vol.9 No.2

The purpose of this study was to suggest the child`s temperament is a factor on the physical fitness of the individual. This study will furnish basic bata available for teaching children to develop their physical abilities by examining the relation between the ages of 4 to 6 in D. L kindergartens, located in E, G ward of Seoul. The Instrument of Children Temperament(KOH Tea-Soon, 1997) was used as a measurement tool for temperament and The Test Of Motor Ability(OH Jin-Koo and 2) was to test physical fitness. SPSS(ver 10.0) was used for the analysis of data, t-test was used to not ify the sexual difference of temperament and physical fitness, Pearson`s correlation coefficient was used for analysing the relation between the subfactor of temperament and physical fitness. The result of this study is as follows. First, the difference(p<.05) of temperament according to the sex appeared in the adaptability and activity levels. Additionally, it was found out that male children are more adaptable to new and changeful environment and more able to adapt to new and changing environments and more physically active than female children. Second, according to the differences between male and female children in physical fitness. females scored higher than males in flexibility(p<.01), coordination(p<.001) and males scored higher than femailes in balance(p<.05). Third, the correlation between temperament and muscular endurance appeared to be positive correlation in distractibility and flexibility and negative correlation in regularity and coordination.

국내 의료종사자에서 HHV-8의 항체양성률에 대한 연구

주우철,최용준,박재은,이혜명,이진수,정문현,김수미,문지혜 대한감염학회 2008 감염과 화학요법 Vol.40 No.4

HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference, In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries, It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6% 1/164) was seropositive, six were equivocal (3.7%,6/164) and 157 people were seronegative (95.73%, 157/164). This study revealed that seroprevalence of HHV-8 in general population was. low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.

기체크로마토그래피를 이용한 산양삼,백삼,홍삼중의 농약잔류 분석

맹주양;이용구;이숙재;정진아;김정미;김선화;김송아 순천향대학교 기초과학연구소 2010 순천향자연과학연구 논문집 Vol.16 No.2

Commercial Korean ginseng-Ginseng cultivated in mountains(GCM), White Ginseng (WG), and Red Ginseng (RG) - were used, respectively, to analyze the pesticide residues in them. The selected pesticides for the analysis of residue were procymidone and tolclofos-methyl. Procymidone residue was no detected in all of them and tolclofos-methy residue was shown as follows: RG(0.270ppm)>GCM(0.0541ppm)>WG(0.007ppm).

국내에서 유행하는 HIV의 전파 경로에 따른 Subtype 분포

이주실,남정구,김성순,강춘,최병선,김옥진,박미선,성봉모,서순덕,전수경,변승옥,신영오,조해월 대한감염학회 2001 감염 Vol.33 No.5

Background : Previous data have been reported that subtype B is prevalent in South Korea, but neither the extent nor the proportion of subtypes could be evaluated. This study was designed to analyze the distribution of HIV-1 subtypes, temporal instructions and transmission dynamics between epidemiological groups. Methods : 1,280 Koreans had been diagnosed as HIV seropositive during the period 1985 to 2000. Among them, 134 individuals were selected for this molecular epidemiological study. 134 DNAs were isolated from uncultured or cultured peripheral blood mononuclear cells. V3-V5 (0.7 kb) fragment of HIV-1 env gene was amplified by nested polymerase chain reaction and was sequenced. Results : HIV-1 isolates from thirty-seven homosexuals were all subtype B (100%). On the other hand, 66 isolates from 94 heterosexuals were subtype B (70%) and 28 were non B subtypes (30% : 13 A, 4 C, 2 D, 8 E , 1 G). Only subtype B strains were isolated from 73 males who were infected with HIV inside Korea while 16 B and 20 non B subtype strains were isolated from 36 males who were HIV infected outside of Korea. However, B and non B strains were isolated half and half from females who were infected inside Korea except one. Conclusion : The HIV-1 subtype B strains are prevalent in Korea from the early HIV infection until present in both homo and heterosexuals. Non B strains have been transmitted from men who were infected outside Korea to their spouses and casual partners. So, we need further study to monitor subtype B and non B HIV transmission in epidemiological groups of Korea, (Korean J Infect Dis 33:311∼318, 2001)

송파농산 기본계획

서주환,변성진,김상범,최미진 경희대학교 디자인연구원 2000 예술· 디자인학연구 Vol.3 No.1

As the standard of living rises and spare time grows, the demand Pattern to the leisure tends, which are on the variety, a high life and a wide area, is changing into total recreation form. As a result, we are so willing to build up sightseeing-leisure site elevating the standard of living in accordance with faciiities and program satisfying desire of new sightseeing form that can contribute development of local society and residents earnings. And according to using the maximum local resource, we are to propose model of minimum-damaged tourist site.

대장암의 예후 인자로서 Thymidylate Synthase 유전자 다형성의 의의

김주형,김영배,최진혁,김정미,정수현,서광욱 대한대장항문학회 2004 Annals of Coloproctolgy Vol.20 No.3

간경변증 환자에서의 위 배출 시간

기주영,채희복,박선미,윤세진,정현용 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

간경변증 환자에서 소화기 증상의 정도와 울혈성 위염, 복수의 유무가 위 배출 시간의 지연과 관련이 있는지 알아보고자 하였다. 대상 환자는 2001년 3월 1일부터 2002년 5월 31일까지 간경변증으로 진단 받은 33명의 환자를 대상(평균연령 54.3세)으로 하였고, 정상 대조군을 위 장관 질환의 과거력이 없고 소화 장애등의 자각증상이 전혀 없으며 위 배출등에 영향을 줄 수 있는 약물 복용이나 전신 질환이 없었던 15명을 대상(평균 연령 30세)으로 하였다. 위 배출 시간검사는 50gm의 달걀 1개에 Tc^(99m)-tincolloid lmCi를혼합하여 고형질화 시킨 TC^(99m)-tin-colloid-steamed egg를 섭취한 후부터 single-head-gamma camera(Picker Co,. USA)을 이용하여 위 배출 시간 반감기(T1/2)를 찾아냈으며 위배출 시간은 T1/2의 평균±표준편차로 표시하였다. 위 배출 시간의 지연은 정상 대조군 T1/2의 mean±1 SD(45.0+12.7분) 이상으로 하였다. 정상 대조군(n=15)의 위 배출 시간은 42.64±16.80분이었고, 간경변증 환자군(n=33)은 42.54±20.80분으로 두 군 사이에 유의한 차이가 없었고, 울형성 위염 및 복수의 유무, 증상점수 4점을 기준으로 하였을 때 위 배출 시간은 두 군 사이에 유의한 차이가 없었다. 식도 정맥류가 있는 군(n=26)과 없는 군(n=7)의 위 배출시간은 각각 49.27±16.80분, 31.71±10.61분이었고, 위 정맥류가 있는 군(n=7)과 없는 군(n=26)의 위 배출 시간은 각각 53.14±11.71분, 43.50±5.85분으로 정맥류가 있는 군에서 위 배출 시간의 지연을 보였으나 통계적으로 유의하지는 않았다(식도 정맥류 p=0.654, 위 정맥류 p=0.991). 혈청 알부민 수치와 위 배출 시간 반감기는 서로 유의한 상관관계가 없었다(p=0.177). 결론적으로, 간경변증 환자에서의 소화불량 증상의 정도와 울혈성 위염, 복수의 유무에 따라 위배출 시간에 차이가 없었다. The purpose of this study was to evaluate whether delayed gastric emptying time(GET) was associated with the degree of gastrointestinal discomfort, congestive gastropathy, and ascites in patients with liver cirrohsis. Thirty three patients, aged 54.3 years, with liver cirrhosis and fifteen control subjects, aged 30 years, without gastrointestinal symptoms and history of gastrointestinal disease were participated from the first of March in 2001 to the 31st of May in 2002. For GET, solid phase gastric emptying was done with radionuclide scintigraphy using single-head gamma camera after ingestion of Tc99m tin-colloid-steamed egg. Delayed GET was defined as the half time period in GET(T1/2) longer than the mean value plus 1SD of controls (45.0+12.7min). GET between Control group and patients with liver cirrhosis was 42.64±16.80min, 42.54+20.80, respectively. Therefore, there is no significant difference. On the base of congestive gastropathy, symptom score '4', and cirrhosis, there is no difference statistically between two groups. GET measured in the group with esophageal varix(n=26) or without esophageal varix(n=7), was 49.27±16.80min, 31.71±10.61min, respectively. GET measured in group with gastric varix or without varix, was 3.14±11.71min and 43.50±5.85min, respectively. But, there is no difference statically between two groups. There was no significant correlation between serum albumin level and T1/2 of GET(p=0.177). This study shows that there is with no apparent clinical difference between gastric emptying time and liver cirrohtic patients with gastrointestinal discomfort, congestive gastropathy, and ascites.

일부 미용업사자의 건강증진행위 실천도와 관련요인

임진주,유선미,류소연,박종 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.1

Background and Objectives:This study identified the performance degree of health promotion behaviors of the workers who are engaged in beauty business, and related factors in order to obtain basic data for development of health promotion program and health education. Method: This study targeted 103 hair dressers and 100 skin specialists who work in Gwangju, and they were interviewed using questionnaire with short answer questions in October 2003. The data collected were analysed using the following devices: descriptive statistics, t-test, ANOVA, Pearson's correlation analysis, and multiple-regression analysis. Results: 1. Health promotion behaviors had 2.76±0.95 when total score was four, which indicated that they had a relatively good management of health promotion behaviors. When specified health promotion behaviors were examined, self-realization had the highest score(2.98±0.58), and exercise had the lowest score(2.03±0.75). 2. When health promotion behaviors of the subjects were examined, there was a statistically significant difference depending on age(P=.025), marriage (P=.000), Position(P=.027), smoking(P=.041), and dhnking(P=.006). 3. It was found that the lower occupational stress of the subjects(r=-0.22, P=.001), the higher the social support(r=0.24, P=.001), and the higher se1f-efficacy(r=0.39, P=.000), the better health promotion behaviors. 4. The predicting factors of health promotion behaviors were smoking, drinking, social support, and self-efficacy, and they explained for 38.1% of health promotion behaviors, Conclusion: Health promotion behaviors of the workers who are engaged in beauty business were affected by various factors. Therefore, in developing future health promotion programs, a careful consideration to reduce stress caused by work and behaviors harmful to health should be given. And to encourage health promotion behaviors, socio-psychological approach through enrichment of social support and self-efficacy should be applied.

마약길항제의 방출 제어형 제제 (제2보) : 나록손 이식제제의 생체적합성 및 약물속도론적 평가 Biocompatibility and Pharmacokinetics of Naloxone Implant

문미란,박주애,이승진,김형국,김길수 梨花女子大學校 藥學硏究所 1995 藥學硏究論文集 Vol.- No.5

For the effective administration of narcotic antagonist, the application of sustained release implantable systems with biodegradable polyphosphazene was examined. Using poly[(diethyl glutamate)-co-(ethyl glycinate) phosphazene]. the implantable devices containing naloxone hydrochloride were prepared and in vivo implantation studies were carried out subcutaneously in rat and rabbit with this preparation for the biocompatibility and pharmacokinetics. The histological finding in rats at initial time period was the inflammation that occurred focally around the implants, but they were showed subsequent mild and limited chronic inflammations and the irreversible changes such as necrosis and degeneration of the muscle or connective tissues were not observed. Therefore the placebo and naloxone implants are considered to be biocompatible formulations histologically. In pharmacokinetic studies, the release of naloxone from the naloxone implants into blood plasma was maintained in 192 hours, but the initial burst effect was observed. If this problem was solved, the application for the narcotic antagonist sustained release systems can be expected.