서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

豆乳 및 Cheese Whey를 利用한 乳酸醱酵

洪在訓,金永培,劉太鍾 建陽大學校 1992 建陽論叢 Vol.- No.1

豆乳를 이용한 乳酸醱酵時 cheese whey를 첨가함으로써 乳酸菌의 醱酵能 및 風味에 미치는 영향을 조사, 醱酵乳로서의 타당성을 검토하였다. 발효용 균주로는 L.bulgaicus와 S.thermophilus의 1:1 혼합 starter를 이용하였으며 얻어진 결과는 다음과 같았다. 유산균의 생육과 산생성, cure 형성에 있어서 가장 적당한 soy milk와 whey의 혼합비율은 9:1이었고 soy milk-whey-mixture (SWM)에 lactose 첨가에 의한 균생육 및 산생성능이 향상되었다. 본 실험조건에서 SWM, soy milk, skim milk 에서 검출된 carbonyl compounds는 acetaldehyde, aceton, tehanol, hexanal, diacetyl등 이었으며 그 중 acetaldehyde가 가장 많았다. 또한 SWM의 amino acid 含量은 glutamic acid, aspartic acid, arginine etc. 順으로 나타났으며 그 영양적 가치는 skim milk나 soy milk에 뒤지지 않았다. 官能檢査의 결과는 色에 있어서 SWM, skim milk, soy milk 사이에 유의차가 없었으며 냄새에서는 skim milk와 다른 두 시료간에 1% 유의차가 있었고 맛에서는 skim milk와 soy milk 사이에 5% 유의차가 있었다. Cheese whey was added to soy milk for lactic acid fermentation by L. bularicus + S.thermophilus and its effects on cell growth, acid production and flavor were investigated. Bacterial growth, acid production and acid formation were best in soy milk concluding 10% of whey. Acid production and bacterial growth were improved by adding of lactose to soy milk-whey mixture (SWM). As volatile carbonyl compounds of SWM< acetaldehyde, acetone, ethanol, hexanal and diacetyl were detected by gas chromatography. AMong them, the amont of acetaldehyde are the largest. The result of sensory test showed no significant difference in taste between fermented skim milk and SWM, and SWM, and SWM and soy milk.

Monte Carlo Computer Simulation에 의한 Neutron Guide의 분석

홍진태,김종율 東亞大學校附設基礎科學硏究所 1996 基礎科學硏究論文集 Vol.13 No.1

Monte Carlo 컴퓨터 시물레이션에 의하여 곡율반경이 주어진 중성자 가이드가 1차원에서 분석되었다. 선택된 가이드는 폭 4.5 mm 높이 50 mm의 단면적과 300 m의 곡율반경을 갖는 소형 가이드이다. 4 Å의 단색, 등방성 중성자원에 의하여 가이드의 입구가 조사되었을 때 가이드의 출구에서 가이드를 통과한 중성자들의 각 및 위치분포가 결정되었다. 또한 transmission 효율, transmitted intensity 및 평균반사 횟수등이 중성자 파장의 함수로 계산되었다. Monte Carlo computer simulation mathod was used to analyze the properties of a one-dimensional curved guide. A simulation code tracing the behavior of neutrons within neutron guide systems was delveloped by authors for determining the transmission characteristics of the curved-neutron gudes. Spatial and angular distributions of the neutrons transmitted along a neutron guide was calculated for a 4 Å mono-energetic isotropic neutron source, neglecting imperfect reflectivity. Transmission efficiency, transmission intensity, and average number of reflections were also calculated as a function of wavelength.

이동형 생체계측을 위한 임베디드 컴퓨팅

홍주현,진계환,박경순,조명찬,박길선,차은종,이태수 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: 초소형 정밀 기계 기술로 제작된 2차원 가속도 센서와 916 MH2 단거리 고주파 데이터 통신 기술을 응용하여 인체의 운동상태를 자동으로 감지하고 분류하는 기법을 제안 하고자 하였다. 재료 및 방법: 인체의 신호를 획득하기 위하여 미국 버클리대에서 제작한 무선 센서를 등 산용 조끼의 전면상단에 부착해서, 대상자의 흉골 부위에 위치하도록 하고, 앉은 상태에서 일어서거나 눕거나 하는 동작 및 그 역동작이 일어날 때, 가속도 센서에서 감지되는 4가지 종류의 파형 현화에 해당되는 데이터를 무선센서 네트웍을 통해 획득하였다. 결과: 획득한 신호를 주성분분석(Principal Component Analysis)과 지원벡터머신(Support Vector Machine)을 사용하여, 2차주성분까지를 도표화하고 클러스터링 함으로써, 4개의 영역으로 분할하는 것이 가능함을 말 수 있었다 결론: 소형 센서들이 작동되는 임베디드 컴퓨팅 환경에서 일상생활 중에 발생하는 인체의 4가지 동작을 자동으로 감지하고 분류하는 것이 가능함을 보였다. Purpose: New monitoring and classifying method of human motion contort was pro- posed by using 2-axial MEMS accelerometer and 916 MHz short-range data communica-tion technology. Materials and Methods: The wireless sensor of MICA mote was attached to a woman mountain vest and located close to the subject's sternum. During four types of sub-ject's motion, that is, sit-to-stand, stand-to-sit, sit-to-tying, and tying-to-sit, waveform changes of the accelerometer data were acquired by wireless sensor network. Results: The acquired signal was analyzed by Principal Component Analysis(PCA) and Support Vector Machine(SVM) technique. By clustering the first and second principal components, four regions corresponding to the four types of motion, were clearly segment-ed. Conclusion: Human motion context during daily life could be monitored and classified automatically by using small sensors in embedded computing environment

2000년 부산광역시 서구에서 발생한 세균성이질 역학조사 평가

홍상기,김정규,전진호,손혜숙,이종태 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Purposes : Bacillary Dysentery is one of the representative infectious disease that widely occurred in recent years, Korea. This study was performed to propose the helpful advices for control of Bacillary Dysentery outbreak based on an assessment of the results of epidemiological survey for Bacillary Dysentery outbreak on May 16, 2000 in Busan. Methods : Subjects were 7,188 peoples who showed diarrhea and contacted with active participants in a religious meeting and suspected cases surveyed from May 16 to May 31, 2000. Direct interview about participation, presence of diarrhea, and history of spring water drinking, and rectal swab on the patients who had diarrhea were done. Results : Among 7,188 peoples, 458 patients had simple diarrhea, and 135 patients confirmed infected with Shigella sonnei. Among confirmed cases. 94.8% had actively participated the religious meeting. The first case occurred on May 10, and consecutive outbreak was concentrated on May 12 and 13. Elementary school children(40.7%) and their parents(35.6%), and women(65.2%) were majority of the confirmed cases. Drinking history of the spring water during the meeting was highly suspected as a cause of this outbreak(odds ratio=3.29, 95% confidence interval=1.59∼6.82). Food intake history was not checked because with low possibility of causing factor. Conclusions : This outbreak appear to be closely related to drinking not sterilized spring water when participating in a religious meeting. However, actual route of transmission was not defined because the epidemiological survey was started six days after the first attack, and, could not find the causative agent in the spring water. The prompt epidemiological survey thought to be essential and important when occurred episode. And also, cooperation with the corresponding health authorities would be very important when the outbreak occurred distant area as this episode. Personal and public concerns and efforts should be sustained to prevent the outbreak and spread-out of Bacillary dysentery.

생물변환 천연식용색소 생산공정기술 개발 : Ⅰ. 홍화 황색소의 안정성에 미치는 pH 및 온도의 영향 Ⅰ. Effect of pH and Temperature on the Stability of the Yellow Pigment from Carthamus tinctorious L.

홍성현,박성길,이종민,한태룡,백영숙,정인식 경희대학교 생명자원과학연구원 1999 硏究論文集 Vol.20 No.-

홍화로부터 열에 의한 안정성을 검토하였다. 황색소의 분해반응은 산성, 중성, 염기성 조건에서 UV/Vis spectral measurement에 의해 조사되었다. 시간변화에 다른 흡광도를 측정해 본 결과 온도가 상승함에 따라 황색소의 분해되는 정도가 점차적으로 증가하는 것을 확인 할 수 있었다. 40℃에서 황색소의 분해 반감기는 pH3.0, pH7.0, 그리고 pH12.0에서 각각 112.1, 39.3 과 25.3 시간이었다. 이것은 황색소가 pH3.0에서 비교적 더 안정함을 말한다. pH3.0, 7.0 그리고 12.0에서 황색소의 activation energy는 각각 519, 15.0 그리고 12.3 kJ/mol이었다 We investigated thermal stability of yellow pigment from Carthamus tinctorious L. Decomposition reactions of yellow pigment were monitored at acidic, neutral and alkaline conditions by UV/Vis spectral measurement. Decomposition of yellow pigment increased as temperature increased Decomposition half lives of yellow pigment at 40℃ were 112.1 39.3, and 25.3 hrs at pH 3.0 , pH 7.0, and pH 12.0, respectively, indicating that yellow pigment is more stable at pH 3.0. The activation energies of yellow pigment at pH 3.0, pH 7.0, and pH 12.0 were 51.9, 15.0, and 12. 3 kJ/mol, respectively.

하이테크 벤처기업의 국제화 요인에 대한 연구 : 정보보호업체를 중심으로 focused on the Korean information security industry

홍성태,전종근,강명수 한국인터넷비즈니스학회 2001 인터넷비지니스연구 Vol.2 No.2

본 연구는 자원의 제약이라는 중소기업이 안고 있는 특성을 갖고 있는 벤처기업의 국제화에 영향을 미치는 요인에는 어떤 것이 있는가를 한국의 정보보호 업체들에 대한 실증 조사를 통해서 살펴보았다. 연구 결과에 의하면, 첨단산업에 종사하고 있는 하이테크 벤처기업의 국제화는 경영자의 주관적 상황인식에 의해 영향을 받으며, 해외진출시 경쟁 양상은 자원의 한계로 인해 가격 경쟁 보다는 기술, 품질 경쟁에 의존하는 경향이 있다고 밝혀졌다. 그 외에도 기존의 국제화와 관련된 여러 요인에서 중요한 변수라고 할 수 있는 국제기업의 규모, 시장의 성숙도, 경쟁강도 등과 같은 요인에 대해서도 고찰하여, 자본금 규모와 경쟁의 강도에 대한 경영자의 기대도 영향을 미치는 것을 알 수 있었다. 연구 대상 기업을 정보보호업체로 한정하여 기업 국제화의 영향요인을 살펴봄으로써 산업특성요인을 제거하였으나 표본 수가 적고 대부분의 기업이 아직도 신생기업의 수준을 벗어나지 못하고 있어 실종분석 결과가 만족스럽지는 못하지만 전체적인 방향은 연구 가설에서 크게 벗어나지 않는다고 할 수 있다. 향후 다른 분야의 벤처기업으로 확장하고 기술적 학습, 다양성 및 진출방식 둥과 같은 다양한 변수를 포함시키는 연구로 발전시켜야 할 것이다. This study examines the factors of venture businesses' internationalization. We conduct empirical research on Korean information security industry which has the weaknesses resulting from the lack of resources like many other small-sized enterprises. As an increasing number of new venture firms arc internationalizing their business operations early in their life cycles, the analysis of the international expansion process of small technology-13ase0 firms is getting more important. Results identif4ed in this study suggest that the internationalization of high-tech venture businesses is influenced by the management attitude to the foreign market and they have a tendency to depend on the competition based on technology or product quality rather than price. Analyzing many other variables such as the size of the firm, the maturity of the market and the competition intensity, we found that the variable like the size in terms of capital and the expectation of the management to the competition intensity are also affecting high-tech ventures' going abroad. This finding has the implication that the venture businesses international expansion relate to environmental conditions like the booming of capital market and the specific circumstance of Korean venture industry.

Treatment of Radioactive Liquid Waste by the Forced-AirCirculation System

Tae-κuk Kim,IL Sik Kang,Jong-Sik Shon,Young-Gerl Ryu,Won-Hyuk Jang,Sang-Min Bae,Young-Yong Ji,Dae-Seok Hong,Kyung-Kil Kwak 한국방사성폐기물학회 2011 한국방사성폐기물학회 학술논문요약집 Vol.9 No.2

국산 알벨다졸(안젠탈^(�))의 臟內線蟲類에 대한 驅蟲效果

蔡鐘一,洪性台,孫運睦,李純炯 대한화학요법학회 1986 대한화학요법학회지 Vol.4 No.1

An anthelmintic trial of albendazole was carried out an total of 186 inhabitants of Namhaegun, Kyongsangnam-do. For this purpose they were examined for their intestinal parasites, by cellophane thick smear and/or anal swab techniques before and 2 weeks after anthelmintic treatment. The examinations revealed A. lumbricoides 5.9%, T. trichiura 26.9%, E. vermicularis 52.4%, Echinostomia sp. 0.02% and Taenia sp. 0.01%. The infected cases were treated with 400㎎ single dose of albendazola. The egg negative conversion rate(NCR) and the egg reduction rate(ERR) were calculated based upon the results of pre and post-fecal examinations. For Ascaris, NCR was 87.5%, ERR 97.1%, and NCR 51.1% and ERR 78.6% for Trichuris. NCR was 100% for Enterobius. Albendazole(Alzental) is regarded as one of recommendable anthelmintics for the nationwide mass treatment programme of intestinal nematodes especially for ascariasis.

공기청정기의 일부 실내공기 오염물질 제거효율에 관한 연구

이태형,김윤신,홍승철,이철민,김종철,전형진,김중호 한국환경과학회 2005 한국환경과학회지 Vol.14 No.5

In this study, we investigated PM_(10), NO₂, and 1-hydroxypyrene(1-OHP) in urine at indoor environments which are 35 houses and 20 hospitals for using air cleaner and non-using air cleaner in Seoul metropolitan area and Kyoung-gi province from April, 2003 to February, 2004. Moreover, we examined effect of improvement for indoor air quality and health effect by concentration of 1-OHP also we investigated removal efficiency by air cleaner for PM_(10), NO₂, and 1-OHP that were 28.5%, 27.4%, and 42.1% respectively. Concentration of PM_(10), NO₂, and 1-OHP were 19.02±18.14μg/m³, 8.66±3.06ppb, and 0.19±0.18μg/g creatinine when air cleaner was no worked. The concentration for PM_(10), NO₂ and 1-OHP were 13.60+10.79μg/m³, 6.29±2.71ppb, and 0.11±0.10μg/g creatinine, respectively. It was significant statistically. Therefore, it is considered using the air cleaner to remove the partial pollutants in indoor environment and is positive effect for health.