급성기 뇌졸중에서 섬망이 기능 회복에 미치는 영향

이종민,김보람,임정훈,고성은,이인식,김종문,김한영,이종민 대한재활의학회 2010 Annals of Rehabilitation Medicine Vol.34 No.4

Objective: To investigate the risk factors for poststroke delirium and evaluate its influence on functional recovery after ischemic stroke. Method: Risk factors for delirium were investigated retrospectively in three hundred twenty nine acute ischemic stroke patients over 60 years of age. Among the 329 patients, sixty seven developed delirium. Data were analyzed between delirium group (n=22) and control group (n=22) according to age, sex, lesion location and clinical features. Korean modified Barthel index (K-MBI), Korean National Institutes of Health stroke scale (K-NIHSS) and Korean mini-mental state examination (KMMSE) were measured at second and sixth weeks after onset and compared for both groups. Results: Parameters showing statistically significant difference between two groups were age over 80, hyponatremia, sleep deprivation, cognitive impairment and cardiogenic embolism. There was no significant difference in K-MBI, K-NIHSS and K-MMSE scores at second week between the two groups. The delirium group showed significantly less improvement in K-MBI and K-NIHSS scores compared to control group (9.5±10.2 vs 18.5±11.6, p=0.011; −0.7±1.2 vs −1.8±1.3, p=0.014). There was no significant improvement in K-MMSE score. Conclusion: The possible risk factors for delirium in acute ischemic stroke are age over 80, hyponatremia, sleep deprivation, cognitive impairment and cardiogenic embolism. Stroke patients with comorbid delirium showed poorer functional outcome. Delirium seems to have detrimental effect in functional recovery after stroke. (J Korean Acad Rehab Med 2010; 34: 403-408)

韓國初期靑磁의 形成과 傳播 -塼築窯와 土築窯를 중심으로-

이종민 한국미술사학회 2003 美術史學硏究 Vol.- No.240

곧 보내겠습니다(번역중..). B4 2장 분량입니다.문의전화 이종민 016-345-2583.. 월화수는 강의중이므로 문자메시지나밤에 연락바람. 사진과 도면은 빠른 등기로 보내겠습니다.원고는 한글 97로 작업함.

고려시대 중기 청자에 대한 새로운 인식 : 장남원 저, 『고려중기 청자 연구』(혜안, 2006)

이종민 이화여자대학교 한국문화연구원 2006 한국문화연구 Vol.11 No.-

국가 대향 레이저 연구시설 소개 - 페타와트 극초단 초강력 레이저 연구시설(PULSER) 구축 및 국내 펨토과학기술 연구 현황

이종민,Lee, Jong-Min 한국광학기기산업협회 2013 光學世界 Vol.144 No.-

펨토초는 1000조 분의 1초를 말한다. $10^{-15}$를 의미하는 단위명이 펨토(Femto)이기 때문에 붙여진 이름이다. 눈을 한 번 깜박이는 시간이 약 10분의 1초, 총알이 물체를 통과하는 데 걸리는 시간이 약 100만 분의 5초인 점을 감안하면 펨토초는 상상하기도 힘들 정도로 빠른 시간인 셈이다. 이런 펨토초 동안 벌어지는 물리, 화학, 생물학적 현상을 연구하는 학문이 펨토과학이며 주로 펨토초 레이저를 이용해 관찰한다. 현재 전 세계적으로 펨토초의 극히 짧은 시간에 1000조 와트(페타와트)의 고출력 레이저를 발생시킬 수 있는 광양자빔 연구시설 구축 사업이 활발하게 진행되고 있다. 국내에서는 광주과학기술원(GIST) 고등광기술연구소가 '극초단 광양자빔 연구시설 설치 운영사업(사업책임자: 이종민 교수)'을 통해 국가 대형 레이저 연구시설인 '페타와트 극초단 초강력 레이저 연구시설(PULSER)'을 최근 구축 완료했다. 이번호에서는 21세기를 이끌 신성장동력 중 하나로 각광 받고 있는 펨토과학기술의 국내 연구 현황과 페타와트 극초단 초강력 레이저 연구시설(PULSER)에 대해 자세히 소개하고자 한다.

高麗時代 寺址 出土 磁器의 器種과 性格 : 생산과 소비의 관점에서 Variety and the Characteristics

이종민 용인대학교 박물관 2004 丹豪文化硏究 Vol.- No.8

Since 1990s, the major achievement in Korean Archaelogical studies includes the excavations of temple sites, where a lot of ceramics has been dug up as their major specimens. The excavations from temple sites reflect the consumptive trend of the monks, the largest consumer group in the times when Buddhism was the dominant religion. Goryeo monks consisted of the social elites and cultural leaders in the hierachical society, so we can say their consumptive trend had a lot of influence on making of the celadon porcelain. It can be summarized briefly according to the data from excavations: porcelain excavations from temple sites can be categorised in celadon, white porcelain, and imported porcelain; historic temples seemed to have consumed common items from the early Goryeo to later times. Among these items, Korean celadons were found in the form of bowl and tea vessels even in the earliest stage. In the Middle Goryeo Dynasty, various everyday vessels appeared in place of bowl and tea vessels; and in later Goryeo celadon items were simplified, usually in the forms of food vessels. Celadons were circulated nationwide if they were in high quality, but if they were in low quality, they came from the kiln near the temples. Compared to this, white porcelain was found in the temples near the workshops, which signified the consumptive pattern different from the ones of the high quality celadon. The import porcelain such as Yaozhouyao-type(燿州窯系 celadon(靑磁), Dingyao-type(定窯系) white porcelain(白磁), Jingdezhenyao-type(景德鎭窯系) qingbaiporcelain(靑白磁, porcelain with bluish-white glaze), Jianyao-type(建窯系) tenmoku(天目, stoneware with black-glaze), Jizhouyao-type(吉州窯系) tenmoku(天目) were found as many as the high quality celadon in proportion and numbers, which was related to the conditions for domestic porcelain production. Especially the celadons with molded design and hard white porcelains in good quality, and black glazed tea bowls were the major imports, which could not be produced found in Goryeo dynasty (高麗) Porcelains from the temple sites consistently corresponded to the products from kilns in each age. This implies most of the kiln products were consumed in temples. As time passed by, the items changed in types, and this might be because the new forms of porcelain from China accelerated the change. Also it was partly due to the gradual change in social institutions. It is not certain how much the temples have contributed to the change, but it is for certain that since the active majority who accepted the new culture of ceramics gathered around the temples. thus playing an important role the change of the types in Goryeo celadon.

게임과 미술치료가 뇌졸중 노인의 인지기능에 미치는 영향

이종민,류성현,박수진 대구대학교 특수교육재활과학연구소 2015 특수교육재활과학연구 Vol.54 No.1

To purpose of the this study was to investigate the effect of game and art therapy on cognitive function for elderly with stroke. 40 elderly stroke patients were randomly allocated to the game program (experiment) group consisting of 14 and the art therapy program(experiment) group consisting of 13, the control group also consisting of 13. The cognitive function of all groups was assessed using a MMSE- K. The result of the present study was the game program (experiment) group and the art therapy program (experiment) group presented significant differences before and after intervention on cognitive function. Therefore, when applying a game program and art therapy program for therapeutic activities for elderly stroke patients, they are believe to help resolve cognitive function impairment of the patients, it is deemed that game program and art therapy program can be usefully applied to improve cognitive unction for elderly with stroke. 본 연구는 게임 프로그램과 미술치료 프로그램이 뇌졸중 노인의 인지기능에 미치는 영향을 알아보고자 실시되었다. 뇌졸중 노인 40명을 게임 프로그램 적용집단에 14명,미술치료 프로그램 적용집단에 13명,대조집단에 13명으로 무작위로 배정하였고, 세 단의 치료 전 • 후 MMSE-K를 실시하여 인지기능을 비교하였다. 그 결과, 게임 프로그램과 미술치료 프로그램을 적용한 집단에서 인지기능이 향상되었다. 따라서 뇌졸중 노인을 위한 치료적 활동으로 게임을 적용한다면 환자의 인지기능 장애를 해결하는데 도움이 될 것이라 사료되고,게임 프로그램과 미술치료 프로그램이 뇌졸중 노인의 인지기능 향상을 위한 중재방법으로서 유용한 것으로 보인다.

Neural Stem Cell Death Mechanisms Induced by Amyloid Beta

이종민,박현희,고성호,최호진 대한치매학회 2017 Dementia and Neurocognitive Disorders Vol.16 No.4

Background and Purpose Amyloid beta (Aβ) is the main component of amyloid plaques, which are deposited in the brains of patients with Alzheimer’s disease (AD). Biochemical and animal studies support the central role of Aβ in AD pathogenesis. Despite several investigations focused on the pathogenic mechanisms of Aβ, it is still unclear how Aβ accumulates in the central nervous system and subsequently initiates the disease at the cellular level. In this study, we investigated the pathogenic mechanisms of Aβ using proteomics and antibody microarrays. Methods To evaluate the effect of Aβ on neural stem cells (NSCs), we treated primary cultured cortical NSCs with several doses of Aβ for 48 h. A 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay, trypan blue staining, and bromodeoxyuridine cell proliferation assay were performed. We detected several intracellular proteins that may be associated with Aβ by proteomics and Western blotting analysis. Results Various viability tests showed that Aβ decreased NSCs viability and cell proliferation in a concentration-dependent manner. Aβ treatment significantly decreased lactate dehydrogenase B, high-mobility group box 1, aldolase C, Ezrin, and survival signals including phosphorylated phosphoinositide 3-kinase, Akt, and glycogen synthase kinase-3β. Conclusions These results suggest that several factors determined by proteomics and Western blot hold the clue to Aβ pathogenesis. Further studies are required to investigate the role of these factors.

특별프로그램 : 대학생프로젝트 경진대회-구두발표 ; 유,공압 실린더 공장의 프로세스 개선을 통한 생산성 향상 연구

이종민,김시성 대한산업공학회 2010 대한산업공학회 추계학술대회논문집 Vol.2010 No.-

Cone Beam Computed Tomography의 두부계측분석을 통한 골격성 제3급 부정교합 환자에서 악교정 수술 후 입술과 주위 연조직의 수직적 변화

이종민,강주완,이종호,김창현,박재억,Lee, Jong-Min,Kang, Joo-Wan,Lee, Jong-Ho,Kim, Chang-Hyen,Park, Je Uk 대한악안면성형재건외과학회 2012 Maxillofacial Plastic Reconstructive Surgery Vol.34 No.5

Purpose: The aim of this study is to evaluate the vertical changes of the lip and perioral soft tissue, following orthognathic surgery in skeletal class III patients by a cephalometric analysis of a cone beam computed tomography (CBCT). Methods: A total of 20 skeletal class III patients, who had bimaxillary surgery with Le Fort 1 osteotomy and bilateral sagittal split ramus osteotomy, were included in this study. The surgical plan for maxilla was posterosuperior impaction with the anterior nasal spine, as the rotation center. Further, the surgical plan for mandible was also posterosuperior movement. The soft tissue changes between lateral cephalogram and CBCT were compared. And the correlations between independent variables and dependent variables were evaluated. Results: There were no significant differences of the soft tissues changes between lateral cephalogram and CBCT. Upper lip philtrum length (SnLs), nasolabial angle increased and upper lip vermilion length (LsStms), lower lip length (StmiB'), lower lip vermilion length (StmiLi), lower lip philtrum length (LiB') and soft tissue lower facial height (SnMe') decreased after surgery. Change of SnLs (${\Delta}$SnLs) was influenced by vertical change of menton (${\Delta}$MeV), and change of LsStms (${\Delta}$LsStms) was influenced by upper lip thickness (ULT). Change of StmiLi' (${\Delta}$StmiLi') were influenced by preoperative overjet. Change of StmiB' (${\Delta}$StmiB') were influenced by preoperative overjet, vertical change of lower incisor (${\Delta}$L1V) and horizontal change of posterior nasal spine (${\Delta}$PNSH). Change of LiB' (${\Delta}$LiB') was influenced by ${\Delta}$L1V and ${\Delta}$PNSH. Change of SnMe' (${\Delta}$SnMe') was influenced by ${\Delta}$MeV, horizontal change of upper incisor (${\Delta}$U1H) and horizontal change of lower incisor (${\Delta}$L1H). ${\Delta}$Nasolabial angle was influenced by change of ULT (${\Delta}$ULT). Conclusion: Both soft tissues and hard tissues can be evaluated by CBCT. Posterosuperior rotation of maxillomandibular complex resulted in increase of upper lip philtrum length and nasolabial angle, while the upper lip vermilion length, lower lip philtrum length, lower lip vermilion length, and soft tissue lower facial height showed a decrease.

Abbe-Estlander 피판을 이용한 하순 결손의 치험례

이종민,오정환,Lee, Jong-Min,Oh, Jung-Hwan 대한악안면성형재건외과학회 2007 Maxillofacial Plastic Reconstructive Surgery Vol.29 No.4

The reconstruction of perioral defects following resection of cancer on the perioral region has been a challenge for oral and maxillofacial surgeons. Surgical management of oral squamous cell carcinoma (SCC) typically involves resection of the carcinoma with a 1cm margin of normal appearing tissue. A large surgical defect is often encountered. The goals of perioral reconstruction are esthetics and function, with oral competence and good lip control. Abbe described the operation that bears his name in 1898, when he reported on the repair of a "conspicuous deformity" in a 21-year-old man born with bilateral cleft lip and palate. Since that time, Abbe flap reconstruction has been used more frequently for repair following resection of malignancies. Large defects of the lips have been repaired with recent modifications of the Abbe flap. The technique has been popularized by Estlander for reconstruction of the lower lip. We have treated 70-year-old male patient with SCC on lower lip using Abbe-Estlander flap. Postoperatively the results showed good prognosis. So we report the result of its treatment and case with review of literatures.