남성 근로자들에서 간기능 검사 이상소견 발생률과 관련요인

하영애,정경동,천병렬 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 근로자의 간기능 검사 이상소견 발생률과 그 관련요인을 알아보고자 일개 화학제품 제조 사업장의 근로자 579명을 대상으로 1997년 10월과 1998년 10월, 2회에 걸쳐 혈액검사 및 설문조사를 실시하였다. 방법 : 간기능 검사 3항목(AST, ALT, γ-GTP)에 대한 2회의 검사에서 모두 이상을 보이는 경우를 간기능 검사 이상소견자로 정의하였다. 일반적 특성(연령, 결혼상태, 학력), 근무부서, 유기용제취급여부, 생활습관(음주, 흡연, 운동, 식이습관), 간질환과거력, 간질환가족력, 약물복용력, B형간염표면항원양성률, 혈당치, 총콜레스테롤치 등을 독립 변수로 처리하였다. 1년 후 간기능 검사 이상소견 발생여부를 종속변수로 사용하였다. 1년 후 추적이 완료된 근로자수는 533명 (92.1%)이었다. 결과 : 간기능 검사 이상소견 연간 조발생률은 100명당 9.6이었고. 연령 표준화 발생률은 9.5이었다. 발생률에 유의하게 관련된 변수는 체질량지수, 음주량, 간질환과거력, 육류섭취였다. (p〈0.05). 다중로지스틱 회귀분석에서는 체질량지수(미교위험도 2.70: 95 % 신뢰구간 1.41∼5.16)와 음주량(비교위험도 1.98: 95% 신뢰구간 1.08∼3.60)이 유의한 변수였다. 체질량지수와 음주량의 변화를 고려한 층화분석결과, 체질량지수가 정상-정상이고 음주량이 소량-소량인 군에 비해 체질량지수가 정상-정상이고 음주량이 과량-과량인 군의 비교위험도가 2.24(95%신뢰구간 1.09∼4.62), 체질량지수가 비만-비만이면서 음주량이 과량-과량인 군의 비교위험도가 5.66(95%신뢰구간 2.69∼11.88)이었다. 결론 : 간기능 검사 이상소견 연간 연령표준화 발생률은 100명 당 9.5이었다. 발생률을 효과적으로 감소시키기 위해서는 체질량지수를 정상으로 유지하고 음주량을 줄이기 위한 적극적인 노력이 필요할 것이다. Objectives : This study was conducted to estimate the incidence of abnormal liver function and risk factors in male employees of an industry in Ulsan City. Methods : Five hundreds and seventy nine male employees were selected as the study cohort and 533 (92.1%) of them were followed after one year. The blood sample was collected to test for AST, ALT, γ-GTP, total-cholesterol, fasting blood sugar and a self-admlnistered questionnaire on life style was done. General characteristics (age, marital status, educational level) , job department, exposure status for organic solvents, life style (alcohol, smoking, exercise, diet) , past history of liver disease, family history of liver disease, drug Intake, HBsAg, blood glucose, total-cholesterol were considered as risk factors. The result of liver function test after 1 year follow-up was treated as dependent variable. The operational definition of abnormal liver function was as follows; those who had abnormal liver functions in the two repealed tests with one month interval. Results : The annual incidence of abnormal liver function was 9.6 per 100 and age-standardized incidence was 9.5. BMI, alcohol, past history of liver disease, and meat intake were significantly related to the incidence (p(0.05) . In multiple logistic regression analysis, BMI (RR=2.70, 95% Cl=1,41-5.16) and alcohol (RR=1.98, 95% Cl=1.08-3.60) were proved as the significant variables. By stratified analysis considering changing pattern of alcohol and BMI, the relative risk of the 'BMI normal-normal and alcohol intake high-high' group was 2.24(95% Cl=7,09-4.62) and that of the 'BMI obese-obese and alcohol intake high-high' group was 5.66 (95% Cl=2.69-11.88) compared with that of 'BMI normal-normal and alcohol intake low-low' group. Conclusions : The age-standardized annual incidence of abnormal liver function was9.5 per 100 in male employees. Thus, an active effort for reducing alcohol intake and controlling BMI should be done to reduce the incidence.

산채류의보존과 일본식 절임

오영애,하귀현,박인경,김미향,김미정,김미경,정자림,이명숙,김순동 대구효성가톨릭대학교 식품과학연구소 1992 식품과학지 Vol.4 No.-

This paper showed the summarization of the preservative method of wild vegetables in the house and the precessing method of Japanese pickles. The preservative methods of wild vegetables were explained devided into long, short term, fresh state, heat treatment and drying. Salt, soybean fermented sauce, soybean fermented paste, lees of refined rice wine and residue in the preparation of bean curd were used as the materials of Japanese pickles.

정신분열병의 임상적 고위험군의 특징 : '서울청년클리닉'의 자연 추적 관찰 예비연구

유소영,이경진,강도형,이승재,하태현,위휘,이애라,송지연,김성년,권준수 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.1

Objectives : The aims of this study were to identify the intake and following process for subjects at high risk of transition to schizophrenia and to examine the neurocognitive, social, and emotional functions of the subjects compared with healthy controls. Methods : Symptomatic individuals judged at high risk for schizophrenia ('clinical high risk') within Youth Clinic were assessed and followed up. They performed a neurocognitive function test, a social function test and an affective function test. Twenty healthy controls were recruited in this study. Results : Among eighty-two subjects contacted through the Youth clinic, sixteen subjects were judged as the clinical high risk group. Fourteen subjects among the clinical high risk group showed deficits in several domains of neurocognitive functions, such as visual recall memory, verbal short term memory and executive function. Social and affective functions are also impaired in the Cli-nical high risk group compared with healthy controls. Two of 15 subjects (13%) developed a psychotic disorder within 6 months. Conclusion : This study illustrates the state of follow-up study for a clinical high risk group. Despite low numbers and short durations, some impairment of several functions in the clinical high risk group suggests possible predictors of psychosis.

확률논리와 조합논리 미형성 학생의 논리지도에 대한 연구

김영신,박애련,임수민,정재훈,김수완,송하영 경북대학교 과학교육연구소 2009 科學敎育硏究誌 Vol.33 No.1

Probabilistic reasoning and combinational reasoning are essential to build a logical thinking and a process of thinking dealing with everyday life as well as scientific knowledge. This research aims at finding the optimal period to teach reasoning to the students who haven't developed probabilistic reasoning and combinational reasoning. The treatment program was performed for 20 students from each grade who couldn't develop two parts of reasoning. The treatment program using baduk stones and cards was performed repeatedly, focusing on the specific activities. After four weeks of treatment program, the test to check the development of probabilistic reasoning and combinational reasoning was performed again and the changes of reasoning development were identified. After giving treatment program for reasoning development, 15.0%, 25.0% and 40.0% of improvement in the 4th, the 5th, the 6th graders respectively were shown. With regard to the combinational reasoning, the results showed the improvement of 20.0% in the 4th grades, 25.0% in the 5th graders and 63.2% in the 6th graders. As a result of research in the above, students, who were not formed probabilistic reasoning and combinational reasoning, could be known to be enhanced through learning, but to fail to be formed the qualitative change like the cognitive development. It is expected that this research can contribute to the improvement of students' cognitive level and there would be more active researches in different fields to improve the cognitive level of the 6th graders who are in their optimal periods to learn two parts of reasoning. 이 연구의 목적은 확률 논리와 조합 논리가 형성되지 않은 학생들에게 논리 지도를 위한 최적의 시기를 찾고자 하는 것이다. 초등학교 4, 5, 6학년 학생 430명을 대상으로 논리의 형성정도를 사전에 검사하였다. 검사도구는 GALT를 참고하여 개발하였고, 이는 과학 교육 전문가에게 타당도를 검증 받았다. 처리프로그램은 두 가지 논리가 모두 형성되지 않은 각 학년 20명의 학생을 대상으로 수행하였다. 이는 바둑돌과 카드를 반복적으로 수행하는 검사도구이다. 4주 뒤 사후검사에서 확률논리와 조합논리의 발달정도를 알아보는 검사를 다시 수행하였고 그 변화는 확인되었다. 확률논리의 경우 4, 5, 6학년에서 형성율이 각각 15%, 25%, 40% 증가하였고, 평균도 .15, .30, .50 증가하였다. T-검증에 의한 의미있는 결과는 6학년 중에서 얻어졌다. 그러나 과도기 학생 비율(21.7%)를 제외하면 형성 학생의 비율은 5.0%로 여전히 저조하였고, 다수의 학생(73.3%)은 미형성 상태를 유지하였다. 조합논리의 경우 4, 5, 6학년에서 형성율이 각각 20%, 25%, 63.2% 증가하였고, 평균도 .20, .25, .63 증가하였다. T-검증에 의한 의미있는 결과는 역시 6학년 중에서 얻어졌다. 그러나 처치 후 논리 형성 학생으로의 전이는 없었으며, 과도기 학생의 비율만 35% 증가하였다. 위의 연구결과, 확률논리와 조합논리가 형성되지 않은 학생들은 학습을 통한 향상은 이루어 졌지만, 인지발달과 같은 질적인 변화는 이루어지지 않았다. 이 연구로 인하여 확률논리와 조합논리의 학습 효과가 큰 6학년 학생들의 인지수준 개선을 위한 여러 분야에서의 더 활발한 연구가 이루어지길 기대한다.

産業災害로 인한 手脂切斷 患者의 療養期間과 診療費의 變異

이종호,이종영,손지연,하영애,박순우,감신,이영숙,김건엽,강윤식 大韓産業醫學會 1997 대한직업환경의학회지 Vol.9 No.3

This study was conducted to analyze variation in patient days and medical care benefits among finger-amputated patients due to industrial injury. The 242 personal data on medical care for finger-amputated patients due to industrial injury(131 in 1994, 111 in 1995) of Regional Labor Office were analyzed. The major results of this study were as follows: Patient days per case were 69. And the ratio of the maximum and the minimum among patient days for case was 26.6. Patient days per case in university hospital were 134.8 and the longest than other medical facilites. The ratio of the maximum and the minimum among the patient days per case was higher in hospital(24.7) than in other medical facilities. Benefits per case were 1,258,000 Won. And the ratio of the maximum and the minimum among benefits of case was 232.0. Case benefits was higher in university hospital (2,685,000 Won) than in other medicl facilities. The ratio of the maximum and the minimum among the benefits per case was higher in hospital(232.0) than in other medical facilities. Variation in patient days and medical care benefits per finger-amputated patient in industrial injury was large. This study results indicated need for a new industrial injury compensation insurance policy initiative for efficient utilization of medical resources and quality assurance. And the author thought that the results of this study would influence the policy for the industrial injury compensation insurance policy.

오감(五感)적 요소를 접목한 브랜드 스페이스 연출 계획 -마임 화장품 프레쉬가든을 중심으로-

김소현,임하영,장효실,최혜원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

인간이 갖고 있는 감각 기관은 시각, 청각, 후각, 촉각, 미각의 총 다섯 가지로, 이를 모두 활용 할 때 이상적 공간 상호작용이 가능하다. 본 연구는 화장품의 공간 연출 계획 시 오감적 요소를 접목하여 브랜드 이미지를 구축하는 일련의 프로세스를 밝히는데 목적이 있다. 이에 본 연구는 2017년 3월~6월 15주간 숙명여대 환경디자인학과 <융합연출디자인> 수업에서 진행된 수업의 결과물로서 작업물을 정리하였다. 그 결과 본 연구는 제품이나 서비스를 직접 경험할 수 있도록 다양한 엔터테인먼트적 요소를 결합하여 기능적 만족감과 더불어 체험적 만족감 제공하는 오감적 디스플레이를 제안하였다. 본 연구는 오감을 활 용한 뷰티 쇼룸으로 감각을 공간에 어떠한 방식으로 적용할 것인지에 대한 정립을 했다는 데에 의의가 있다. 아울러 다양한 매체와 공간의 개념이 일반화 되어 가는 오늘날 기업 환경 속에서 오감적 체험을 기반으로 한 공간연출은 가상의 공간속에서도 유연하게 적용 가능한 디스플레이 요소로 확인되었다. 또한 본 연구는 향후 이와 관련된 쇼룸 공간 개발에 있어서 기초 자료로 활용될 것으로 기대된다.

정신분열병의 유전적 고위험군에서 인지, 정서 및 사회기능 연구

이경진,위휘,유소영,이애라,송지연,하태현,홍경수,김명선,권준수 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.1

Objectives : Vulnerability marker in biological relatives of schizophrenia may be very useful in identifying the propensity for the development of schizophrenia. This study suggests that the relatives at risk for genetically developing schizophrenia have impairments in several domains of cognition, social function and affective function as a vulnerability marker. Methods : A neurocognitive function test, a social function test and an affective function test were administered to fifteen healthy relatives from families with two or more patients with schizophrenia (geneticallly high risk subjects). Fifteen healthy controls matched for age and gender were recruited in this study. Results : Compared to the control subject, the genetic high risk subjects performed significantly more poorly in the selective attention and recall memory of neurocognitive function. The high dsk subjects also had lower scores in independence-performance and independence-competence of the social function test and emotion control of the affective function test. Conclusion : Selective attention, recall memory, independence-performance, independence-competence and emotion control ability may be a valuable marker for genetic study of schizophrenia.

피질이형성증과 동반된 난치성 간질의 외과적 치료

김형일,김연희,이민철,정애자,권지현,최하영,Andre Palmini 啓明大學校 醫科大學 1995 계명의대학술지 Vol.14 No.2

The advent of neuroimaging technique has enabled the accurate diagnosis of structural abnormalities associated with intractable epilepsy. Among these, neuronal migration disorders(NMDs) or cortical dysplasias(CDs) involving cerebral cortex are increasingly recognized as a major cause of intractable epilepsy. CDs are expressed as variety of forms depending upon the time of injury to the developing nervous system. CDs are highly and intrinsically epileptogenic. It is crucial to completely resect the epileptogenic zone in focal CDs for better seizure outcome. Hemispherectomy or multilobar resection is preferred for hemimegalencephaly. Callosotomy can be chosen in the diffuse CDs who have intractable drop attacks. However, resective surgery can benefit the selected patients with diffuse CDs if localizing information persists.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

A Model of NGO activity for family peace and brighter society

Ha, Young-Ae Center for the Reconstruction of Human Socity, Kyu 1999 OUGHTOPIA Vol.14 No.1