기존단독주택지의 도로변 주차에 관한 연구 : 목포시 산정 1동을 중심으로 Focused on the Detached Housing Area Sangjung 1 Dong in Mokpo City

박정현,조용준 조선대학교 국토개발연구소 1997 국토개발연구 Vol.17 No.1

This study examines parking types, methods and hours on existing detached housing areas at Sanjung 1 dong, Mokpo-city, carried out the questionnaire of class characteristics, possession of vehicle and using pattern of parking space for the residents and then the following conclusions are obtained. 1. 60% of respoding households posses the car, but the cases with parking lot are just 2.0% and over of car owners parked their cars illegally on the road, and the most sinificant reason of illegal parking is the lack of parking facilities(74%). 2. On the possession of car by that of house, homeowers of respoding households are 0.63 car/households and lessees are 0.65 car/households. 3. On the parking conditions on the road of housing area, there is a difference by a day of the week, but it begins to be decreased from 07:00, increased from 18:00 and it is the peak on 23:00. 4. most of the respondents (90%) agree to the contruction of paid parking iot and in this case, the appropriate distance to houses is within 50m and in the opinion of enforcement of car shed certification and of double taxation of two cars per households, 60% of the respondents (60%) agree to this. To sum up the above conclusions, the road of existings detached house is the stage of the conflicts among neighbors as well as the violation of walking right due to illegal parking cars on the roda and it is urgent to secure the parking space due to the construction of multi-household houses. However, since it is difficult for existing detached housing area to secure the security of parking space due to the narrow housing area and the unclear road limit in housing area, the methods which use the common parking facilities by developing surrounding idle area, idle space of public agencies and existing housing site should be examined and for this, the various incentive system should be arranged and operated

개 아토피성 피부염 장기치료 1례

박은정,윤기영,박정호,이왕희,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2011 動物醫科學硏究誌 Vol.18 No.1

A 7-year-old male castrated Shih-tzu dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University for severe pruritus. On physical examination were confirmed systemic erythema and alopecia, crust on the neck and flank region. Tape strip test identified numerous degenerative neutrophils and severe Malassezia infection. Treatment for severe pruritus was applied with systemic antihistamine therapy and topical therapy with antimicrobial shampoos. For the finding of appropriate treatment of atopic dermatitis, it was chosen six immune-related treatments. And clinical sign scores were evaluated by investigator with CADESI-03 after each application of six treatments. Application of human immunoglobulin G and leflunomide showed the remarkable regression of lesions.

개에서 이중 결찰법을 통한 동맥관 개존증의 완치 예

윤헌영,정순욱,박희명,박철,정만복,김준영,한현정,황민,노병국,박상혁,장하영,박정윤 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

A ten months old, female Yorkshire terrier weighing 2.88 kg referred to veterinary teaching hospital of college of veterinary medicine, Konkuk University because of syncope, cough and dyspnea. First hematological and serum chemical test revealed thrombocytopenia, mild anemia, and increase of concentration of ALP (195 U/L). On 57 days later, second hematological and serum chemical test revealed polycythemia, increase of concentration of ALP (211 U/L), and Tchol (387 mg/dl). Right atrium enlargement, main pulmonary artery bulge and cardiomegaly (VHS = 11.5) were observed in radiographic findings. Ultrasonographic images showed both right and left ventricular dilation and turbulent flow between the descending aorta and the main pulmonary artery in color Doppler imaging. ECG showed left ventricular enlargement, SA block, and electrical alternant. Thoracotomy was performed through left fourth intercostal incision under isoflurane anesthesia. Patent ductus arteriosus was double ligated with 1-0 silk. Cough and dyspnea disappeared on 5 days after operation. Turbulent flow was not found in color doppler imaging of ultrasonography on 10 days after operation. Ten months later after the operation, syncope could not exist any more.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1

Ko, Yeon Uk,Kim, Su-Jeong,Lee, Juhyung,Song, Min-Young,Park, Kang-Sik,Park, Jun Bae,Cho, Hyun-Soo,Oh, Young J. Elsevier 2019 Parkinsonism & related disorders Vol.66 No.-

<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>Most cases of Parkinson's disease (PD) are sporadic, but genetic variations have been discovered in PD patients. PARK7/DJ-1 is a known cause of early-onset autosomal-recessive PD and is implicated in neuroprotection against oxidative stress. Although several post-translational modifications of DJ-1 have been proposed, phospho-modification of DJ-1 and its functional consequences have been less studied.</P> <P><B>Methods</B></P> <P>Putative phosphorylation sites of DJ-1 were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS analysis). Subsequently, phosphorylation site of DJ-1 was confirmed by <I>in vitro</I> kinase assay and cell-based pull-down assay. Impaired dimer formation of phospho-null mutant was measured using DSS crosslinking assay and immunoprecipitation assay. To evaluate physiological consequences of this event, protein stability of DJ-1 WT and DJ-1 phospho-null mutant were compared using cycloheximide chase assay and ubiquitination assay.</P> <P><B>Results</B></P> <P>Here, we showed that DJ-1 directly bound to the catalytic subunit of protein kinase A (PKAcα). We found that PKAcα is responsible for phosphorylation of DJ-1 at the T154 residue. Interestingly, dimerization of DJ-1 was not detected in a DJ-1 T154A mutant. Furthermore, stability of the DJ-1 T154A mutant was dramatically reduced compared with that of wild-type DJ-1. We found that DJ-1 T154A was prone to degradation by the ubiquitin proteasome system (UPS).</P> <P><B>Conclusion</B></P> <P>We identified a novel phosphorylation site of DJ-1. Furthermore, we determined protein kinase A that is responsible for this posttranslational modification. Finally, we demonstrated physiological consequences of this event focusing on dimerization and protein stability of DJ-1.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PKAcα phosphorylates PARK7/DJ1 at the Thr154 residue. </LI> <LI> Disruption of Thr154 phosphorylation is linked to a lower stability. </LI> </UL> </P>

설악산국립공원 설악폭포 분비나무와 잣나무 1 m 수고생장 기간 조사

최은비(En-Bi Choi),박준희(Jun-Hui Park),김진원(Jin-Won Kim),김요정(Yojung Kim),서정욱(Jeong-Wook Seo) 국립공원연구원 2021 국립공원연구지 Vol.12 No.2

설악산국립공원 설악폭포에 위치한 아고산대 침엽수인 분비나무와 잣나무의 수고생장 기간을 조사하기 위해 본 연구를 수행하였다. 조사를 위해 분비나무 고사목 2본(SAPPAND01, 02)과 잣나무 고사목 1본(SAPPPKD03)을 선발하였다. 높이별 수고생장 기간을 조사하기 위해 뿌리와 줄기 경계를 기준으로 높이 0, 10, 20, 30, 40, 50, 60, 80, 100 cm에서 디스크를 채취하여 나이테(이하, 연륜) 분석을 실시하였다. 또한 고사연도 분석을 위해 생육중인 분비나무 15본에서 생장편을 채취하여, 연구지를 대표하는 연륜폭연대기를 작성하였다. 연륜 분석 결과, 분비나무인 SAPPAND01과 02의 생육 기간은 각각 102년(1915-2016)과 97년(1918-2014)이었으며, 잣나무인 SAPPPKD03은 62년(1926-1987)이었다. SAPPAND01과 02의 고사 시기는 각각 2016년 가을-2017년 봄과 2015년 여름-가을이었으며, SAPPPKD03의 고사 시기는 1987년 가을-1988년 봄이었다. 100 cm까지 수고생장을 하는데 소요되는 기간은 SAPPAND01이 41년으로 가장 길었으며, SAPPAND02와 SAPPPKD03은 각각 17년과 18년으로 조사되어 수종보다는 개체 간 차이가 큰 것으로 확인되었다. 하지만, 대상목 모두에서 수고 20 cm 전후까지 생장하는데 소요되는 기간은 공통적으로 긴 것으로 나타났다. 본 결과는 향후 우리나라 아고산대 침엽수 수령조사의 정확성을 향상 시키는데 중요한 기초자료가 될 것이다. This study aimed at investigating the height-growth duration of Abies nephrolepis and Pinus koraiensis which are the tree species growing in the subalpine area at Seorak Falls of the Seoraksan National Park. For the study, two dead Abies nephrolepis (SAPPAND01, 02) and one dead Pinus koraiensis were selected. To investigate the height-growth duration, 9 disks were collected at the height of 0, 10, 20, 30, 40, 50, 60, 80, 100 cm height from the collar to upward from the sample trees, and then their ring-width were measured. The site master chronology used to the reference to date the death years of the sampled trees was established using the increment cores from 15 living Abies nephrolepis. Through the tree-ring analysis, the ages of SAPPAND01 and 02, and SAPPPKD03 were verified 102 (1915-2016), 97 (1918-2014), and 62 years (1926-1987) years, respectively. The death seasons and years of SAPPAND01 and 02, and SAPPPKD03 were autumn in 2016 - spring in 2017, summer - autumn in 2015, and autumn in 1987 and spring in 1988, respectively. The height-growth durations up to 100 cm from the collars of SAPPAND01 and 02 and SAPPPKD03 were -41, 17, and 18 years, respectively, so that it was verified that the height-growth duration was not changing depending on tree species but individual trees. During the juvenile periods growing up to approximately 20 cm from the collar, however, all sample trees showed relatively taking long times. All results obtained from this study would be fundamental data to improve the accuracy of examining the age of conifers in the subalpine areas.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

Passive Sampler를 이용한 진주시 NO_2 농도 분포

박정호,전기일,서정민 진주산업대학교 농업기술연구소 2000 農業技術硏究所報 Vol.13 No.-

In 1996, about 80 % of total emission in Chinju was emitted from mobile source, with about 26.9 % of nitrogen dioxide (NO_2) coming from mobile source. In this study, the distributions of NO_2 concentrations were investigated with Passive Sampler in Chinju. Passive Sampler can be a useful method to evaluate distribution of a detailed concentration in large area. The concentrations of NO_2 in downtown Chinju were appeared in the rage of 0.0046∼0.0285 ppm. And the concentrations of NO_2 in rural areas were appeared in the rage of 0.0018∼0.0176 ppm at the road side and 0.0014∼0.0064 ppm at the green zone. The mean concentration of NO_2 was appeared to be about 0.0043(±0.0020) ppm in Chinju. The NO_2 concentrations at the downtown site were about 21∼98 times higher than in rural areas.

실비우스 수도를 경유한 뇌낭미충 낭종의 이주 -증례 보고-

김정훈,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

충수염의 임상적 고찰과 초음파의 유용성

박정배,양혁준,김형수,황성연,박철완,이근 대한응급의학회 1995 대한응급의학회지 Vol.6 No.2

Appendicitis is the most common acute abdomen in Emergency Medical Center & outpatient department. But sometimes, it is difficult for us to diagnose because of clinically variable symptoms. We reviewed the ultrasonographic findings and analyse 521 cases of appendectomy patients about its distribution of sex and age, seasonal prevalence, clinical symptom and signs, laboratory findings, duration from onset of symptom to arrival at hospital, duration from arrival at hospital to operation, vital signs, operative results, and associated diseases, which were treated at the department of General Surgery & Emergency Medical Center in Chung Ang Gil Hospital from July, 1994 to June, 1995. The results were as follows : 1. The most common age group was second decade. And male to female ratio was 1.43:1. Seasonal variation was not significant. 2. Of 521 cases, 141 cases(27.1%) visited the hospital within 24 hours from the onset of symptom, and 259 cases(49.7%) visited between 24 to 48 hours. 3. In duration from arrival to operation, the cases within 6 hours were 263 (50.5%), the cases between 6 and 12 hours were 131(25..1%). 4. In systolic blood pressure, cases below 90mmHg were 19(3.6%), cases above 160mmHg were 23(4.4%). Below 60mmHg diastolic pressure were 55 cases(10.6%), cases above 110mmHg were 9(1.7%). In pulse rate, above 90 rate/min were 171(32.8%). 5. On admission leukocytosis was found in 413 cases(79.3%) and 342 cases of them were pathologic appendicitis. 6. Ultrasoundgraphy was performed in the 87 cases, but 23 cases were suggested appendicitis. Among 23 cases, 22(95.7%) revealed pathologic appendicitis at ooperation and labortatory examination. Of the 64 cases which were normal on ultrasonography, only 2 cases(3.1%) were proved to be appendicitis. 7. The results of 496 operations without ultrasonography were appendicitis in 390 cases(78.6%), mesenteric lymphadenopathy 36(7.3%), pelvic inflammatory disease 28(5.6%), fecalith 15(3.0%), terminal ileitis 8(1.6%), diverticulitis 7(1.4%), urinary tract stones 5(1.0%), cecal cancer 2 cases, right ovarian tumor 2 cases, tubo-ovarian abscess 2 cases, grater omentum internal hernia 1 case. Our results showed that the sensitivity of ultrasonohraphy was 95.8% and the specificity 98.4% in the diagnosis of appendicitis, It suggests that the ultrasonography is very helpful in the diagnosis & differential diagnosis of acute appeendiditis.