2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

Pd/titania 촉매에 의한 아세틸렌 Cyclotrimerization

정용화,이태진,김기석 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.1

Pd/titania 촉매에 의한 아세틸렌 cyclotrimerization의 반응성과 생성물 분포의 변화를 상압조건하의 373K에서 flow reaction 실험에 의해서 연구하였다. 주요 생성물로서 에틸렌과 벤젠이 얻어졌으나 시간이 경과함에 따라서 촉매의 피독으로 인하여 아세틸렌 전화율이 급격히 감소하였다. 일정한 반응기체 유속(공간속도 4,000hr^(-1))에서 아세틸렌 농도를 50, 25, 12.5 vol%로 감소시켰을 경우 벤젠 생성량은 감소하였으나 촉매의 피독은 완화되었다. 아세틸렌 농도 변화에 대한 벤젠 생성량의 비교에 의해서 벤젠 생성반응이 아세틸렌 농도에 대해 1차 반응임을 확인하였다. 또한 일정한 아세틸렌 농도 (25 vol%)에 대하여 공간속도를 4,000 hr^(-1)에서 6,000 hr^(-1)로 증가시켰을 경우 촉매의 피독이 완화되었으며 벤젠 생성량도 증가하였다. Flow reaction에 의한 아세틸렌 cyclotrimerization에 있어서 촉매 피독을 완화시키고 벤젠 수율을 증대시키기 위해서는 반응기체 흐름의 아세틸렌 농도와 유속의 최적화가 필요해 보인다. 본 연구에 있어서 palladium-titania 계면의 oxygen anion vacancoies와 환원된 titania 표면이 종전의 연구자들 보다 100K 낮은 온도에서의 벤젠 생성에 기여한 것으로 추정된다. Cyclotrimerization of acetylene was studied by means of atmospheric flow reaction at 373 K on Pd/titania catalyst to investigate variations of catalytic reactivity and product distribution. While ethylene and benzene were obtained as the major products, rapid decrease in acetylene conversion resulted from catalyst poisoning with the lapse of reaction time. For a fixed flow rate(space velocity 4,000hr^(-1)), as acetylene concentrations decreased from 50 to 25, to 12.5 vol%, benzene yields decreased, whereas catalyst poisoning was attenuated. Comparison of benzene evolution signals from the variation of acetylene concentrations showed that the rate of benzene formation is first-order in acetylene pressure. In addition, for a fixed concentration(25 vol%) of acetylene, as space velocity increased from 4,000 to 6,000hr^(-1), benzene yields also increased and catalyst poisoning was attenuated. Optimization of acetylene concentration and flow rate may be necessary to accomplish the attenuation of catalyst poisoning as well as enhancement of benzene yield from acetylene cyclotrimerization by flow reaction. It can be deduced from this study that oxygen anion vacancies at palladium-titania interface and reduced titania made contributions toward catalytic activity for benzene formation at the temperature 100 K lower than those reported by previous researchers.

상온스웨이징 나사 철근 이음한 철근콘크리트 인장부재의 피로거동

정영화,박용석 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.B

As material needs have been increasing with recent economic growth, it is a current tendency that the magnitude of load applied to structure has been rising. With improved technique of product materials, steel and concrete have been stranger than ever so the danger of fatigue damage increases as permanent action of repeated loads. In case of deformed steel bars widely used in reinforced concrete structure, when they are product in factory, there will exist same parts connecting the steels. Such connections are easy to be weakened by permant action of repeated loads. It is a real condition in Korea that there is lack of research of it. As a result of estimating fatigue characteristic of Pressure Welded joints with the steels that are oftenly used and producted in domestic it is showed that there are no remarkable difference in fatigue strength. Because there is no detail which is refered in Civil Specification, this paper will be the basic data being added in later Specification.

댄스스포츠 참가자의 참여동기 분석

정용각,정은화 부산 외국어 대학교 2002 外大論叢 Vol.24 No.-

The purpose of this study was to examine and analyze the motives for participation of participants in Dance Sport by classifying with variable factors such as frequency, period, initiating reason, and so forth. The results of this analysis by various factors are as follows. First, by personal experience, there were experienced person showed higher rather than an inexperienced person in the competence, health and fitness, and affiliation factors, and an inexperienced person showed higher rather than an experienced person in amotivation. Second, by period, the period from 6 months to 1 year appeared high compared to the period from 3 to 6 months and from 1 to 2 years in the ability factor as an interior motive and the health and physical factor and the social factor as exterior motives. Third, the participation motive in the 30s by age appeared high in the ability factor as an interior motive. In case participants were younger, the ability factor more affected th participation for getting dance sport techniques. Fourth, by frequency, 3 to 4 times a week was shown higher rather than 1 to 2 times a week.

콘크리트 포장의 플라이애쉬 재활용 방안연구

정영화,최성용,윤경구,용석응,김태경 강원대학교 석재복합신소재제품연구센터 1998 석재연 논문집 Vol.3 No.-

한국 대부분의 고속도로는 콘크리트로 포장되고 있으며, 플라이애쉬를 포장용 콘크리트에서 재활용하면 콘크리트의 성능을 향상시킴과 동시에 경제적 이익과 환경보호에 큰 기여를 할 것이다. 본 연구에서는 플라이애쉬를 포장 콘크리트에 재활용하고자, 플라이애쉬 치환율, 물-시멘트비, 굵은골재 최대치수를 주요실험 변수로 하여 이들이 플라이애쉬를 혼입한 포장용 콘크리트의 역학적 특성에 미치는 영향을 살피기 위해서 실험하여 통계처리 분석하였다. 이러한 분석결과를 바탕으로 포장 콘크리트의 적정배합을 제시하였으며 결과는 다음과 같다. 플라이애쉬를 혼입한 포장콘크리트의 휨강도에 영향을 미치는 인자는 플라이애쉬 치환율이 가장 큰 것으로 나타났으며, 다음으로 굵은골재 최대치수와 물-시멘트비 순으로 영향을 미친다. 또한, 플라이애쉬 치환율과 굵은골재 최대치수의 상관관계가 가장 큰 것을 알 수 있었다. 목표압축강도를 목표 휨강도의 6배로 선택하여 적정구간을 결정하였으나, 적정배합구간이 목표압축강도에 의해서 결정되었다. 이는 플라이애쉬의 작은 수화물이 공극을 효과적으로 채움으로써 휨강도의 증진에 크게 기여하기 때문으로 판단된다. 고속도로 포장에 적용할 수 있는 32mm의 굵은골재 최대치수와 45%의 물-시멘트비를 사용하는 목표 휨강도 45kg/㎠의 적정배합에서는 5.0%까지 플라이애쉬를 치환 가능하고, 50kg/㎠의 적정배합에서는 2.5%까지 치환 가능하다. 공항 포장에 적용할 수 있는 40mm의 굵은골재 최대치수와 37%의 물-시멘트비를 사용하는 목표 휨강도 45kg/㎠의 적정배합에서는 4.5%까지 플라이애쉬를 치환 가능하고, 50kg/㎠의 적정배합에서는 2.0%까지 치환 가능하다. The most of highway in Korea have been paved by concrete since last ten years. The recycling of fly ash in pavement concrete may result in economics, the improvement of concrete quality and the reservation of environment. This paper focused on the series of experiment and statistics analysis with experimental variables such as fly ash substitute ratio, water-cement ratio and maximum size of coarse aggregate in order to investigate the feasibility of recycling of fly ash in pavement concrete, to see the strength characteristics and t propose the optimum mix design based on previous results. The results of experiments and analysis were follows; The fly ash substitute ratio affected most seriously to the flexural strength of concrete among main variables, followed by maximum size of coarse aggregate and water-cement ratio. The interaction between fly ash substitute ratio and coarse aggregate size was the biggest. The optimum mix design was determined by target compressive, which was selected as 6 times of flexural strength. This indicated that the small hydrate of fly ash in concrete filled in effectively and resulted in the enhancement of flexural strength. the optimum mix design for highway pavement concrete with 32mm of maximum size of coarse aggregate and 45% of W/C can incorporate up to 5.0% and 2.5% of fly-ash at 45 kg/cm² and 50 kg/cm² of target flexural strength, respectively. The optimum mix design for airport pavement concrete with 40mm of maximum size of coarse aggregate and 37% of W/C can incorporate up to 4.5% and 2.0% of fly ash at 45 kg/cm² and 50 kg/cm² of target flexural strength, respectively.

금속담지 촉매를 이용한 아세틸렌의 삼합체 고리화 반응

정용화,박노국,김기석,이태진 한국공업화학회 2003 응용화학 Vol.7 No.2

Cyclotrimerization of acetylene to benzene was investigated on Pd/titania as a means to utilize acetylene as the feedstock for synthesis of valuable hydrocarbons. Literature indicated Pd and titania posses the activity for the reaction with relation to the density of Pd (111) plane and reduced titanium ions. Study of catalytic activity, product selectivity, and catalyst stability under varying catalyst specification and reaction condition has to be further conducted to develop a competitive process for the reaction. Our research investigated the effect of Pd loading, additional metal oxide, and reduction treatment upon the catalytic behavior of Pd/titania for the reaction in the laboratory scale.

Dense Kondo 계인 CeTe의 광학적 성질

정명화,김재민,권용성 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.1

Dense Kondo계인 CeTe와 정상금속인 LaTe의 크기 양질인 단결정을 개선된 Bridgeman방법으로 성장시켰다. 이 단결정을 이용하여 0.05∼8eV의 광범위한 에너지 영역에서 반사율을 측정하여, Kramers-Kronig변환을 통해 광학전도도를 얻었다. 광학전도도의 스펙트럼을 분석한 결과, CeTe와 LaTe의 경우 모두 p-d 전이에 의한 두 개의 피크가 3.6eV와 5.1eV에서 발견되었다. 이 두 피크의 형성 mechanism은 5d-band의 입방결정장에 의한 것임을 알았다. 그리고 CeTe의 경우는 LaTe에 없었던 4f-5d전이에 의한 피크가 0.4eV에서 발견되었다. 이는 XPS 스펙트럼으로부터 얻은 bare 4f-전자의 binding 에너지(약 1.5eV)에 비해 매우 작은 값이다. 이 편차는 local field를 고려한 Lorentz모델을 적용함으로서 잘 설명되었다. 또한, localization의 정도로 약 0.4의 값을 얻었다. 끝으로, 띠내전이의 해석으로부터 LaTe의 경우보다 CeTe의 경우가 전도전자의 유효질량이 무겁다는 사실을 얻었다. 이것으로부터 CeTe의 여기상태인 Γ_8와 전도전자 간의 Kondo 교환상호작용의 에너지가 매우 크다는 것을 알았다. We had grown the high quality single crystals of dense Kondo system CeTe and normal metal LaTe by using the advanced Bridgeman method. The reflectivities of the single crystals were measured in wide energy range from 0.05 to 8eV, and their optical conductivities were obtained using Kramers-Kronig transformation. By the result of their optical conductivity spectra, two peaks due to p-d transition were discovered at about 3.6 and 5.1eV, respectively. The double peaks were explained by cubic crystalline electric field. And in case of CeTe, extraordinary peak due to f-d transition, which LaTe had not, was appeared around 0.4eV. This value was well explained by the Lorentz model considering the local field. The degree of screening due to conduction electrons was evaluated to be about 0.4. The effective mass of conduction electron of CeTe was large compared with that of LaTe. From this, we could obtain the fact that in CeTe, Kondo exchange energy between conduction electron and excited Γ_8 state was very large

FDTD 기법을 이용한 도파관과 공동의 결합 해석

鄭白鎬,李華鎔,李範雨 호서대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.19 No.-

In this paper, an investigation of microwave coupling between waveguide and cavity with a lossy dielectric material by the Finite- Difference Time-Domain (FDTD) method is undertaken. We have assumed that the waveguide is excited by the magnetron which is modeled as a monopole with a delta gap source or frill generator. Numerical simulation indicates that the shape of cavity becomes very important when predicting the dissipated power distribution for a lossy dielectric material inside a cavity.

Poly(2-hydroxyethyl methacrylate-co-γ-methacryloxypropyl triethyl silane) 및 Poly(2-hydroxyethyl methacrylate-co-γ-methacryloxypropylmethyl bistrimethyl siloxysilane)의 반응성과 열적 성질

성용길,정태화,이상영 동국대학교 1986 論文集 Vol.25 No.-

Hydrophilic poly(2-hydroxyethyl methacrylate) has been accepted as biocompatible material for medical applications. Some of its relatively poor physical property are still remained as problems to be improved. In order to improve its physical property, new copolymers of 2-nhydroxyethyl methacrylate(HEMA) with silane monomers have been developed and synthesized. The silane monomers are γ-methacryloxypropyl triethyl silane(MPTS) and γ-methacryloxypropyl methyl bistrimethyl siloxysilane(MPMBSS). The compositions of unreacted monomers in the copolymers were separated and determined by the intensity of each peak by gas chromatographic analysis. The monomer reactivity ratios determined by the Kelen-Tu¨dos method are as follows; r_1=0.80 and r_2=0.71 for poly(HEMA-co-MPTS), r_1=1.22 and r_2=0.21 for poly(HEMA=co-MPMBSS). The tendency of alternating copolymerization and the relative reactivty of MPTS and MPMBSS with HEMA were investigated. The Q and e values were also calculated by the Alfrey-Price equation. The synthesized monomers and copolymers were identified by infrared spectroscopy and nuclear magnetic resonance spectroscopy. The thermal properties of the copolymers were also measured by thermogravimetry and differential scanning calorimetry.

抗癌丹을 投與한 大腸癌 患者 83例에 대한 臨床報告

이용연,서상훈,유화승,최우진,조정효,이연월,손창규,조종관 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

Climical studies were carried out 83 cases of patients with colorectal cancer treated bv Hangamdan(抗癌丹) from January lth 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by colorectal cancer, by sex, showed that Male is more then Female, by age, showed that the numbber of fifties is majorith. 2. distribution of diagnostic stage, in descending order; stage Ⅲ(53%, top), stagew Ⅵ(45.8%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(83.3%) and combined treatment of westem and oriental therapy(92.1%)were boserved. The effects of the symptoms were as folows: diarrhea(37.3%),abdominal pain (25.3%), general body weakness(22.9%), nausea(20.5%) and etc. in orders. 4. Analysis of hematology attached by colorectal cancer, maintenance and increasing of WBC(89.9%), RBC(74.7%), Hgb(81.1%), Platelet(92.4%) were Observed. After taken Hangamdan, the satety of the liver and kidney were as follows; maintenance and decreasting of AST(85.9%), ALT(94.8%) , GTP(87.5%), Creatinine(90.9%) were observed. 5. of IL-12 and IFN-λ attached by colorectal cancer, increasing of IL-12(53.3%), IFN-λ(80%) were observedl. 6. Analysis of QOL attached by colorectal cancer, maintenance and improvement of combined treatment of western and oniental therapy(89.6%), traditional oriental therapy(83.3%) were observed. 7. Analysis of survival in patients with Ⅳ stage of colorectal cancer, above 7 months(18.4%), 12 months(65.8%). 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(83.3%) and maintenance and improvement of combined treatment of western and oriental therapy(80.5%) were observed. Analysis of tumor marker attached by colorectal cancer, maintenance and decreasing of CEA(78.8%) were boserved 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(83.3%), combined treatment of westem and oriental therapy(72.7%) were observed.