정신보건관련시설 입원(소)자의 주요 정신장애 유병률 : 전국 20개 시설의 입원(소)자를 대상으로

조성진,조맹제,서동우,함봉진,홍진표,배재남,이준영,이동우,박종익,전홍진,김성주,김용익 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

Objectives : One of the objectives of this study is to estimate the prevalence rates of psychiatric diagnoses in the combined populations of psychiatric hospitals, psychiatric nursing facilities and homeless asylums using the Korean version of the Composite International Diagnostic Interview (K-CIDI), which is a comprehensive and fully standardized interview schedule to assess psychiatric disorders for diagnosis. The Other objective is to compare with previously studied prevalence rates of Psy-chiatric diagnoses using the results of this study. Methods : The study subjects, aged from 181o 64 years, were randomly selected from 64,582 institutionalized population of psychiatric hospitals, Psychiatric nursing facilities and homeless asylums as of 30, June, 2001. Twelve trained interviewers administered the K-CIDI to the selected respondents. A total of 1,875 respondents (male 1,194, female 681) completed the interview. Results : The lifetime and one year prevalences of any diagnosis excluding nicotine dependence · withdrawal, anxiety disorder, eating disorder, somatoform disorder were 88.2% (male 88.1%, female 88.3%), and 65.8% (male 62.7%, female 73.7%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were 78.5% (male 75.3%, female 83.7%), and 56.8% (male 51.9%, female 64.8%), respectively. The lifetime and one year prevalences of alcohol use disorder (dependence/abuse) were 26.7% (male 37.9%, female 8.3%), and 8.7% (male 12.8%, female 2.1%), respectively. The lifetime and one year prevalences of mood disorder were 18.1% (male 13.5%, female 25.8%), and 10.4% (male 7.2%,female 16.9%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were comparable with the 2001 community survey by 1.19% to 1.32%, and 0.51% to 0.61%, respectively. The lifetime and one year prevalences of schizophrenia were also comparable by 0.16% to 0.28%, and 0.16% to 0.25%, respectively. There were no significant changes of prevalence rates when correction were applied to other psychiatric diagnosis. Conclusion : The results of this study could be used for evaluating the distribution of psychiatric diagnoses in mental health related facilities and for planning mental health policies.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

老齡者의 建康을 위한 生活習慣 實態調査

申東敏,長鳳愚,李揆文,金賢俊,金昌範,崔宗洙,崔鍾晥,李鍾珏,金圭碩,趙庚旭,金鍾聲,朴鍾振 平生體育硏究所 論文集 1987 平生體育硏究所 論文集 Vol.2 No.-

With a view to examining the habit and method in which old people maintain and improve their health, we consulted 551 men and 444 women who were over 65 years old, and concluded as follows: 1. Habit of eating It's been revealed that most of the old people keep a regular eating hour, control the quantity of meal or eat a little food, and prefer vegetables to meat. 2. Mental health Old people feel the necessity for mental health and most of them (about 80%) keep good mental health without becoming pessimistic. Their chief concenrs have turned out to be about their sons and daughters and their own health and finance. 3. Managing Good Health It has been revelaed that old people do not possess any special kind of secret to keep good health but taking plenty of rest, regular meal, and proper exercise, and many of them (about 60%) have been shown to eat invigorant food that they can easily get around their living area. 4. Physical Functions It has been revealed that many old people are conscious of some symptoms about their parts of body and about to percent of them suffers from neuralgia. Some measures like medical aid especially for old people need to be taken as soon as possible. As we have found that the health-keeping method of old people consists plenty of rest, proper exercise, and appropriate nutrition, we can conclude that the recreatonal and culture facilities and programs for keeping old people in good health should be developed. It is also necessary to study food that contribute to their health and develop ways to get rid of the stresses to which they are exposed in their daily life. Presides, it is natural that government found an administrative department to deal with these matters effectively.

한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

한국어 판 구조화 임상면담도구 개발 : 신뢰도 연구

한오수,안준호,송선희,조맹제,김장규,배재남,조성진,정범수,서동우,함봉진,이동우,박종익,홍진표 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 정신장애의 정확한 진단과 평가는 임상에서뿐만 아니라 신뢰성 있는 연구를 위해서도 매우 중요하다. Structured Clinical Interview for DSM-IV(SCID)는 임상전문가들이 사용하는 진단도구로서, 비교적 짧은 시간에 정확한 진단을 내릴 수 있다. 본 연구는 한국어판SCID를 개발하고 그 신뢰도를 평가하기 위해 수행되었다. 방법: 국문학자가 포함된 번역위원회를 통하여 연구용판 SCID를 번역한 후, 정신과 의사 2인과 임상심리학자 1인에게 한국어판SCID 실시방법을 교육시킨 뒤 한국어판SCID를 이용한 면담의 평가자간 신뢰도 (interrater reliability)를 검증하였다. 면담 대상은 1999년 2월에서 3월까지 2개 병원 정신과에 치료중인 환자 90명(남:41명, 여:29명)이었다. 결과: 현재 장애(current disorder) 평가에서 주요 우울장애, 기분부전장애, 정신분열병, 알코올 남용 및 의존, 기타 물질 남용 또는 의존, 여러 불안장애들 및 섭식장애 등과 같은 대부분 장애의 kappa값은 .70이상으로 매우 높았다. 그 이외의 양극성 장애, 망상장애, 광장공포증, 감별 불능 신체화 장애 및 건강염려증의 kappa값도 .69에서 .40사이로 수용할 수 있는 정도였다. 평생 장애(lifetime disorder)에서는 양극성 장애(k=.69)와 감별 불능 신체화장애(k=.59)를 제외한 다른 모든 장애의 kappa값이 .70이상이었다. K-SCID 면담시 Ⅰ축 질환에 대하여 흔하게 다중 진단이 내려졌으며, 평균 진단 수는 1.5∼1.7개로 나타났다. 결론: 한국어판 SCID는 신뢰도가 높은 진단도구로 생각되며, 향후 정신질환의 정확한 진단과 임상연구에 유용하게 사용될 수 있다. Objectives: Accurate diagnosis and assessment for psychiatric disorders is crucial for research, as well as for clinical practice. Structured Clinical Interview for DSM-Ⅳ(SCID-RV) is a less time-consumimg and more accurate structured diagnostic interview form. It can be used by clinical professions and is known for a reliable diagnostic tool. Present study was conducted to develop Korean version of SCID-RV and to test the inter-rater reliability. Methods: The authors have translated original SCID-RV into Korean, and revised in parallel with sociocultural background of Korea. Ninety patients from two psychiatric hospitals, both outpatient and inpatient, were interviewed and rated independently by three raters. Results: The kappa coefficients for most of illnesses, such as major depressive disorder, dysthymia, schizophrenia, alcohol abuse and dependency, anxiety disorder and eating disorder were excellent(>0.70) in the evaluation of current disorders. And the kappa coefficients for bipolar disorder, delusional disorder, agoraphobia, undifferentiated somatoform disorder, and hypochondriasis were acceptable(>0.40) in the evaluation of current disorders. In the evalua-tion of lifetime disorders, the concordant rates of all the diagnoses except bipolar disorder and undifferentiated somatoform disorder were excellent. Lack of hierarchy in DSM-Ⅳ allows for multiple Axis I diagnoses. Mean numbers of Axis I diagnoses per subject assigned by the three raters were 1.5-1.7. Conclusions: Our findings confirm that SCID-RV yields highly reliable diagnoses. SCID-RV is recommended for accurate diagnosis in clinical practice and research on psychiatric disorders.

백서에서 Sodium Taurocholate 투여로 유발시킨 급성 췌장염의 형태학적 연구

우종철,김창진,강상균 순천향대학교 1992 논문집 Vol.15 No.2

Acute pancreatitis is relatively common, as the incidence of which is 11 to 22 per 100,000. Recent studies suggest that both the incidence and prevalence may be increasing, particularly among middle-aged elderly women. Usually the disease has benign course, but 25%∼60% patients dies of the early and late complications as shock, acute renal failure and ARDS. The causes of the disease are diverse; cholelithiasis, pancreatic duct obstruction, viral infection, pancreatic post-poeration, hypercalcemia, post renal transplantation, some drugs as azathioprine, thiazide and sulfonamide. Among these, bile reflux to pancreatic duct by gallstone impaction in the opening of a common anatomic channel between the bile duct and pancreatic duct is considerd to be the most common cause of acute panereatitis. As the acute pancreatitic tissue is not available easily, most of the morphological stydies depend on animal models caused by artificial reflux of bile and duodenal contents by loop, infusion of biles in biliopancreatic duct and choline deficient diet supplemented with 0.5% methionine. This study is conducted by light microscopic, transmission and scanning electron micorscopic examinations of the pancreas to see the morphological changes of acute pancreatitis induced by taurocholate infusion in the bilio-pancreatic duct in rats. The results were as follow : 1. The taurocholate infusion in bilio-pancreatic duct caused elevation of amylase in the blood, which is the sign of acute pan creatitis. 2. Grossly, the pancreas showed interstitial and peripancreatic edema at 30 minutes after infusion. Focal pancreatic necrosis and hemor-rhage are noted at 1 hour after infusion, and hemorrhage and fat necresis are seen at 3 hours after infusion. 3. Light microscopically, the pancreatic acinar cells focally degenerated, accompanied with interacinar edema at 30 minutes after infusion. Severe interstitial edema, acute inflam matory cells infiltration and hemorrhage appeared at 1 hour after infusion. massive fat and pancreatic necresis with iterstitial hemorrhages are noted at 3 hours after infusion. 4. Trasmission electron microscopical examinations revealed dilatation of rough endoplasmic reticulum, decreased zymogen granules with heterogeneus both in size and shape and lysis of basement memebrane at 30 minutes after infusion.Some zymogen granules were devoid of membrane and others showed halo and fusion. The ultrastructural changes are progressive accoding to the lapse of time after infusion. 5. Scanning electron microscopocally, the normal pancreas acinar cells showed numererous zymogen granules, which were round with smooth surface and homogenous in size and shape. Thirty minutes after infusion, the zymogen granules are decreased in number, irregular in size and shape, and fine granular debris were attached on the surface of granules. The intercellular spaces were widened. Three hours after infusion, some fine fibrillary materials are noted around wrinkled irregular granules. Above results suggest that taurocholate infusior in bilio-pancreatic ducts might induce acute hemorragic pancreatitis in rats by toxie effect to plasma membranes and zymogen granular membranes, and in part by acitvation of some proenzymes, but further studies are necessory to clucidate pathogenetic mechanisms of acute hemorrhagic pancreatitis.

[논문]토사터널 굴착시 발생하는 구조물의 부등침하 억제용 마이크로파일의 효과에 관한 연구

박진우,권정근,임종철 釜山大學校生産技術硏究所 2007 生産技術硏究所論文集 Vol.66 No.-

도심지에서 건설되는 각종 터널 시공시 현장여건 동 그 특수성에 따라 지중 및 지상에 존재하는 각종 인접구조물에 대한 안정성 확보가 필수적인 요건으로 대두되고 있다. 따라서 이같은 문제를 극복하면서 깊은 기초로서의 역학적 특성을 가지며, 현장의 적용성 및 시공성/ 경제성 등 여러 가지 장점을 가진 마이크로파일을 적용함에 있어서,선행연구에서 규명되어진 역학적 특성을 통해 파일의 적절한 보강형식과 현장의 적용성 및 보강의 효율성을 높이기 위한 수치해석을 실시하고/ 터널 인접구조물의 부등침하 안정검토 해석결과와 현장여건을 고려한 마이크로파일의 보강각도와 길이에 대한 효율적인 보강대책을 제시 하고자 한다.

알지네이트 비드를 이용한 메틸 오렌지의 봉입 및 방출에 미치는 키토산의 영향

변종찬, 이상은. 장우석, 이은주, 최진석, 박정숙 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

In this study, methyl orange-loaded alginate beads were prepared and compared to investigate the effect of chitosan on the encapsulation and release of hydrophilic methyl orange in alginate beads. Particle size and encapsulation efficiency of alginated beads were determined. Swelling ratio and disintegration of al-ginate beads were investigated in gastrointestinal environment. Particle size of beads was 1.1-1.5 mm and shape was spherical. Weight of beads was increased depending on the content of chitosan. Content of chitosan affected on the encapsulation of methyl orange. Encapsulation of methyl orange in alginate beads without chitosan was 15%, while encapsulation efficiency was increased with addition of chitosan. Beads were not disintegrated in HCl solution (pH 1.2) within 4 h, with floating and swelling. Swelling ratio of beads was in-creased to 222%. Release of methyl orange from alginate beads without chitosan was up to 70% within 2 h in HCl solution (pH 1.2). When chitosan was added to the alginate beads, release of methyl range from beads was significantly reduced. It is supposed that release of methyl orange from beads is resulted from diffusion and erosion of beads, which is pH-dependent. In condusion, chitosan-alginate beads have potentials to control release of small hydrophilic drugs by the addition of chitosan.

과학교사에 관한 선행연구 분석

우종옥,정진우,홍성일 한국교원대학교 과학교육연구소 1995 청람과학교육연구논총 Vol.5 No.1

There were many studies on the science teacher. Also, there were many researches on the science teacher education. What seems to be needed is more analysis and synthesis of these results. In this study, the results of preceding-research were analyzed and categorized. The study subjects were preceding-researches published on the 'Journal of the Korean Association for Research in Science Education' and the 'Science Education' of America. The results of this study were as follows: The trend of research on science teacher and teacher education became more various and diverse. The domain of research were categorized in three: (1) Teacher Character(of Cognitive and Affective), (2) Teacher Education(of in-service and pre-service), (3) Professional Practice (of Teaching). The implication of this study was that it was more necessary to investigate on the teacher's teaching strategies.