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Culex pipiens pallens 모기의 난황단백질 합성에 대한 Hormone의 영향
조정래,박영민,강석희 성균관대학교 기초과학연구소 1988 論文集 Vol.39 No.2
Culex pipiens pallens모기의 난황단백질 합성에 대한 brain hormone과 β-ecdysone의 영향에 대하여 조사하였다. 흡혈하지 않은 모기에게 β-ecdysone을 주사하였을 때 주사 후 12시간에 최대의 vitellogenin 합성을 나타내었다. 흡혈 후 decapitation 이나 ligation된 모기중 maturing ovary를 가진 모기의 vitellogenin 합성율은 decapitation이나 ligation이 지연될수록 증가하였다. 흡혈 후 decapitation이나 ligation된 모기중 maturing ovary를 가진 모기의 vitellin level은 decapitation이나 ligation이 지연될 수록 증가하였다. 이 결과는 C. pipiens 모기의 난황단백질 합성은 brain hormone과 β-ecdysone이 조절할 가능성을 제시해 주고 있다. Injection of β-ecdysone into unfed Culex pipiens pallens(Diptera: Culicidae) females stimulated incorporation of ^3H-leucine into proteins by the fat body in vitro. The rate of incorporation began to rise by 6 hours and reached at a maximum at 12 hours after ecdysone injection. Blood fed decapitated females produced maturing and arrested ovaries. The fat bodies of females with arrested ovaries failed to synthesize proteins, while fat bodies from females with maturing ovaries produced vitellogenin even when the females were decapitated within few minutes after a blood meal. The yolk deposition into the ovaries for females with maturing ovaries was not affected by decapitation.
조정래 광주보건대학 2004 論文集 Vol.29 No.-
We proposed and tested a scheme to segment lung image and bronchus image depicted in CT examinations. A lung segmentation scheme was proposed based on watershed algorithm and a bronchus segmentation was proposed based on threshold transform. The lung segmentation scheme includes a series of six steps. 1) reading from CT image 2) the first image segmentation 3) filtering the foreground object marker 4) filtering the background object marker 5) applying the final watershed 6) the visualization. The bronchus segmentation scheme includes a series of four steps. 1) reading from CT image 2) the low-pass filtering 3) the grayscale reconstruction 4) applying the threshold This paper can ultimately be integrated into computer schemes for quantitative analysis and diagnosis of lung disease.
天然染料에 관한 硏究(6)-치자색소에 의한 셀룰로오즈섬유의 염색
趙慶來,張貞戴 新羅大學校 1993 論文集 Vol.36 No.1
Optical behaviors and dyeing properties of color solution extracted from Cape Jasmin were investigated. The wavelength of maximum absorption of color solution differed with solvent. The amount of colors extracted was increased with extracting time. but does not concerned extracting temperature. Dye content of fibers was related to concentration of the dye in solution and dyeing time. The value of apparent diffusion coefficients(Da) increased and the value of standard affinities of dyeing(-△u°)decreased with increasing dyeing temperature. respectively. The standard heats of dyeing (△H°), variation of entropy(△S°)and activation energy(Eact) were calculated to be -3.698kcal/mol. -9.0225cal/mol·deg and 1.781kcal/mol, respectively.
Culex pipiens pallens의 난황단백질 합성에 관한 연구
강석희,박영민,조정래,문정희 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2
Anautogenous한 모기인 한국산 집모기 Culex pipiens pallens의 난황단백질 합성에 대한 hormone 들의 효과를 조사하였다. 피를 먹지않는 c. pipines 암모기의 head extract를 decapitation한 Aedes atropalpus에게 주사하였을 때 난성숙이 재유발되었으며, 난성숙의 재유발 정도는 우화 후 주사시기가 지연될수록 증가하여 우화 후 24시간에 주사하였을 때 최고에 도달하였다. 피먹은 C. pipiens를 흡혈 즉시 decapitation 또는 abdominal ligation하여도 난성숙이 저지되지 않았다. 이러한 결과는 C. pipiens의 brain hormone은 헙혈 즉시 방축되기 시작하여 난성숙의 시작을 자극하는 것으로 여겨진다. 피를 먹지않은 C. pipiens 암모기에게 β-ecdysone을 주사하거나 또는 head extract 주사 후 JHI을 처리하였을 때 fat body가 합성하는 vitellogenin의 양이 증가하였다. The effect of brain hormone, Juvenile hormone and β-ecdysone on the synthesis of vitellogenin in the anautogenous mosquito, Culex pipiens pallens, has been examined. Head extract from non-blood fed C. pipiens females, when injected into the decapitated Aedes atropalpus females, stimulated egg maturation. The ovarian development in C. pipiens was not completely blocked by decapitation or abdominal ligation performed immediately following a blood feeding. These results suggested that the release of brain hormone in this mosquito may be triggered by a feeding activity. Injection of β-ecdysone or head extract followed by topical application of JH into non-blood fed C. pipiens females stimulated vitellogenin synthesis. These results supported the previous work in Aedes aegypti that brain hormone, JH and ecdysone, in that sequence, are required for the egg maturation.
동일한 혈관 내에 발생한 이식형 약제 주입기 카테터의 위치이상
오대석,김영재,김명훈,조광래,임세훈,이정한,이근무,정순호,신치만 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-
저자들은 56세 여성 환자의 왼쪽 쇄골 하 정맥에 시행한 이식형 약제주입기 카테터의 삽입 후 발생한 비정상 위치에 대한 증례를 보고하고자 한다. 카테터의 끝은 환자의 늘 어진 가슴, 체위, 신체의 움직임, 카테터의 유동성 등의 영향으로 천자된 정맥 내에서 견인되고 뒤쪽으로 이동하였다. 환자는 어떠한 증상도 호소하지 않았지만 비정상 위치의 카테터는 심각한 합병증을 유발할 수 있기 때문에 제거되었다. 따라서 시술자는 약제주입기 삽입 전에 환자의 신체 상태와 단순 흉부 촬영상을 확인하고 카테터의 비정상 위치가 발생할 수 있는 위험 징후를 알아차려야 하겠다.
Rocuronium의 애별투여방법이 모지내전근의 이완에 미치는 영향
최영균,김승수,이원진,조광래,이상은,김영환,임세훈,이정한,이근무,정순호,김영재,신치만 인제대학교 2009 仁濟醫學 Vol.30 No.-
Objective : There are controversies in pnmmg technique of rocuronium whether it can or can't shorten the onset time. We want to compare the effects of two different priming doses and intervals of rocuronium. Materials and Methods : After giving propofol, 50 patients were randomly assigned to 5 groups. Group I received a placebo, followed 3 min later by rocuronium 0.6 mg/kg. Priming doses and intervals of Group II, Ill, N, V were 0.06 rng/kg and 2 min, 0.12 mg/kg and 2 min, 0.06 rug/kg and 3 min, 0.12 mg/kg and 3 min, respectively. Total dose of rocuronium was 0.6mg/kg. Train of four (TOF) count or ratio and 1st twitch height of TOF (T1) were monitored with 15 secondsintervals. TOF ratio of each groups just before bolus injection, duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were compared. Results : Duration for TOF count to reach zero and duration for Tl to reach 95% depression after bolus injection were decreased in priming groups compared to Group 1 (P < 0.01) In group V, significant depression of TOF ratio just before bolus injection was seen (P < 0.05). Conclusion : Priming technique with rocuronium is effective method to shorten the onset of neuromuscular block. But priming dose of rocuronium itself could cause hypoxia and aspiration in awake patients and should be used carefully. Priming dose of rocuronium 0.06 mg/kg and 2 minutes interval maybe relatively safe method.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
필라델피아 염색체 양성 급성골수성백혈병에서 Imatinib Mesylate로 분자학적 관해를 유도한 후 성공적인 자가 말초혈액 조혈모세포이식이 시행되었던 1예
김여경,이제중,이병환,변정래,조덕,이일권,정익주,양동욱,김형준 대한조혈모세포이식학회 2003 대한조혈모세포이식학회지 Vol.8 No.1
저자들은 필라델피아 염색체 양성 급성골수성백혈병 환자에서 복합항암화학요법으로 혈액학적 완전관해를 유도하고, imatinib mesylate를 이용하여 분자학적 관해를 유도한 후, 성공적으로 자가 말초혈액조혈모세포이식을 시행하였던 1예를 경험하였기에 이를 보고하는 바이다. Philadelphia chromosome (Ph¹)-positive acute myeloid leukemia (AML) is very rare disease, comprising 3~4% of the AML, and is a clinically distinct entity with poor clinical outcome with conventional chemotherapy. We report a case of Ph¹-positive AML who underwent successful autologous peripheral blood stem cell transplantation after achieving a molecular remission with imatinib mesylate.
극단 저체중 신생아에서의 동맥관 개존증 결찰술을 위한 진정맥 마취 경험 2례
최영균,고명진,이상은,조광래,김영환,임세훈,이정한,이근무,정순호,김영재,신치만 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-
Running title: Cases of anesthesia for extremely low birth weight infant. Extremely low birth weight infants (birth weight < 1000 g) are prone to various morbidities such as respiratory distress syndrome, intraventricular hemorrhage, periventricular leukomalacia, patent ductus arteriosus, necrotizing enterocolitis and retinopathy. To accomplish successful anesthetic management, many precautions must be continuously taken during the operation. First, inspired oxygen concentration should be adjusted to avoid oxygen toxicity. Second, body temperature must be maintained adequately. Third, hemodynamic parameters should be kept stable. We report 2 cases of successful anesthetic management for extremely low birth weight infant who underwent ligation of patent ductus arteriosus at the neonatal intensive care unit.