S-470 Relationships between blood pressure and clinico-pathological findings in IgA nephropathy

( Hyung-seok Ihm ),( Da-rae Kim ),( Jin-sug Kim ),( Kyung-hwan Jeoung ),( Tae-won Lee ),( Chun-gyoo Ihm ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Objective: Several factors contribute to the development of hypertension in patients with IgA nephropathy (IgAN). This study was conducted to find the relationships between baseline blood pressure (BP) and clinico-pathological findings in patients with IgAN and normal renal function. Design and Method: Clinico-pathological findings were analyzed in a total of 163 patients with IgAN and serum creatinine ￡ 1.1 mg/dL from The Kyung-Hee Cohort of Glomerulonephritis. The glomerular surface area (GSA) was determined using imaging analysis software. The serum and urine angiotensinogen (AGT) concentrations were measured using human ELISA kits.?Results: Mean serum creatinine concentration was 0.86 (0.5~1.1) mg/dL. Systolic BP was ≥ 130 mmHg in 72 patients (44%) and ≥ 140 mmHg in 42 (26%). Patients with systolic BP ≥ 130 mmHg as compared with those <130 mmHg had higher GSA and tubulointerstitial fibrosis and showed worse follow-up clinical findings: higher concentrations of serum creatinine, larger amount of proteinuria and lower levels of GFR. Systolic BP was positively correlated with age, baseline and follow-up proteinuria, serum uric acid concentrations and IgM deposit and negatively with follow-up GFR and the slope of change in 1/serum creatinine for 2 years, while it has no significant relationships with serum and urine AGT and 24 hour urinary sodium excretion. Conclusions: This study showed that systolic BP was associated with renal progression and pathological findings, glomerulomegaly and tubulointerstitial fibrosis, in patients with IgAN.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

Korean speech sound development in children from bilingual Japanese-Korean environments

Kim, Jeoung-Suk,Lee, Jun-Ho,Choi, Yoon-Mi,Kim, Hyun-Gi,Kim, Sung-Hwan,Lee, Min-Kyung,Kim, Sun-Jun The Korean Pediatric Society 2010 Clinical and Experimental Pediatrics (CEP) Vol.53 No.9

Purpose: This study investigates Korean speech sound development, including articulatory error patterns, among the Japanese-Korean children whose mothers are Japanese immigrants to Korea. Methods: The subjects were 28 Japanese-Korean children with normal development born to Japanese women immigrants who lived in Jeonbuk province, Korea. They were assessed through Computerized Speech Lab 4500. The control group consisted of 15 Korean children who lived in the same area. Results: The values of the voice onset time of consonants /$p^h$/, /t/, /$t^h$/, and/$k^*$/ among the children were prolonged. The children replaced the lenis sounds with aspirated or fortis sounds rather than replacing the fortis sounds with lenis or aspirated sounds, which are typical among Japanese immigrants. The children showed numerous articulatory errors for /c/ and /I/ sounds (similar to Koreans) rather than errors on /p/ sounds, which are more frequent among Japanese immigrants. The vowel formants of the children showed a significantly prolonged vowel /o/ as compared to that of Korean children ($P$<0.05). The Japanese immigrants and their children showed a similar substitution /n/ for /ɧ/ [Japanese immigrants (62.5%) vs Japanese-Korean children (14.3%)], which is rarely seen among Koreans. Conclusion: The findings suggest that Korean speech sound development among Japanese-Korean children is influenced not only by the Korean language environment but also by their maternal language. Therefore, appropriate language education programs may be warranted not only or immigrant women but also for their children.

담도 낭선종에서 기원한 담도 낭선암 1예

이현경,서기열,신태림,김승정,이선영,문일환 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.2

담도 낭선종에서 기원한 담도 낭선암 1예

이현경,문일환,이선영,서기열,신태림,김승정 대한소화기학회 1998 대한소화기학회지 Vol.32 No.2

Biliary cystadenocarcinoma is a rare malignancy and occurs predominantly in middle aged woman. Its clinical manifestation is nonspecific and not distinctive from benign cystic lesion. Sonography and computed tomography usually show a septated, multiloculated cystic mass with varying degrees of mural and septal thiekening. Ultrasonography and/or CT have been used for guidance in the percutaneous aspiration of the cystic fluid and needle biopsy. We report one case of biliary cystadenocarcinoma, which arised from cystadenoma in a 67-year-old man, with a review of literature.

자기 베어링을 사용한 고온 히트펌프용 무급유 원심 압축기의 성능평가를 위한 실험장치 구성

고희환(Hee-Hwan Ko),정동진(Dong-Jin Jeoung),김경엽(Kyung-Yup Kim) 한국유체기계학회 2018 한국유체기계학회 학술대회 논문집 Vol.2018 No.7

메타분석을 활용한 프로스포츠 구단 및 기업의 사회적 책임(CSR)활동이 이미지에 미치는 영향력의 효과검증 : 구단, 기업 이미지를 중점으로

최경환(Choi, Kyung-Hwan),김소영(Kim, So-Yung),이정학(Lee, Jeoung-Hak) 한국체육과학회 2021 한국체육과학회지 Vol.30 No.4

This study found that social responsibility (CSR) activities of professional sports teams and companies are important lawyers who positively influence public perception. At a time when Corona 19 is facing difficulties in economic, social, and sports fields, we hope that it will lead to a change in the image of domestic demand, sports welfare, community cooperation, and problem solving is as follows. In order to objectively and comprehensively examine the social responsibility (CSR) activities of professional sports teams and companies, eight Korean academic journals and six academic papers were selected according to the selection criteria. Excel 2016, R program, and CMA3 are used for analysis, and the conclusion is as follows. Firstly, it was confirmed that the overall effect of social responsibility activities of professional sports teams and companies on the image is very large. Secondly, the impact on the image of social responsibility activities on the sub-factors (economy, charity, ethics, law) was greatest, followed by charitable, ethical, and legal factors. Third, there was a significant difference in the influence of social responsibility activities in the form of publication on the image. Fourth, there was a significant difference in the effectiveness of socially responsible activities by image type (company, baseball team, brand, team).

태권도 경기장 서비스품질이 지역이미지 및 재방문의도에 미치는 영향 : 지역이미지의 매개효과 검증을 중심으로

이정학(Lee, Jeoung-Hak),최경환(Choi, Kyung-Hwan),김욱기(Kim, Wook-Ki) 한국체육과학회 2019 한국체육과학회지 Vol.28 No.3

The purpose of this study is to identify the influence of Taekwondo stadium’s service quality on regional image and intention to revisit by focusing on the mediating effect of regional image. For the research target, this study conducted survey on audiences who visited the stadium to watch Taekwondo match. The questionnaires were distributed to the audiences and total of 337 questionnaires were used on the result analysis. For data processing, this study used SPSS 22.0, SPSS MACRO (model no.4), frequency analysis, factor analysis, reliability analysis, multiple regression analysis, and mediating effect verification. The research results were as follows. First, among the service quality factors at Taekwondo stadium, tangibility, reliability, and sympathy had significant influence on the regional image. Second, among the service quality factors at Taekwondo stadium, sympathy, responsiveness, certainty, tangibility, and reliability had significant influence on intention to revisit. Third, The regional image life style and convenience factor had a significant influence on the revisit inquiry. Fourth, in the relationship between the Taekwondo stadium’s service quality and intention to revisit, the regional image had significant mediating effect. This study analyzed the regional image and intention to revisit focusing on the Taekwondo stadium’s service quality. This study holds meaning for suggesting the marketing strategy for increasing audiences for Taekwondo match, enhancing regional image, and promotion revisiting.

메타분석을 활용한 스포츠 마케팅믹스(4P)요인이 소비자행동에 미치는 영향 : 관람만족, 이용만족 영향력을 중심으로

이정학(Lee, Jeoung-Hak),최경환(Choi, Kyung-Hwan),조혜경(Cho, Hye-Kyung) 한국체육과학회 2021 한국체육과학회지 Vol.30 No.1

The study was conducted on domestic academic journals and degree papers published from 2000 to April 2020 to objectively and comprehensively grasp the impact of marketing mixes in the sports sector on satisfaction factors. According to the selection criteria of this study,, 12 dissertations and 9 academic journals were selected as the final analysis subjects, and the conclusions based on the results are as follows. First, the overall effect size of the sports marketing mix on satisfaction was identified at a moderate level. Second, the effect size was the highest for the satisfaction according to the sub-factor of the sports marketing mix, and the effect size was shown in the order of location, price, and facilitation factors. Third, there was no significant difference in the influence of sports marketing mix on satisfaction according to the type of publication. Fourth, The size of marketing 4Pmix by type of satisfaction was found to be satisfactory for viewing and using.

스포츠 가상현실(VR)을 체험한 척수 장애인의 프레즌스(Presence)가 몰입 및 스포츠 관여도에 미치는 영향

이정학(Lee, Jeoung-Hak),최경환(Choi, Kyung-Hwan),조혜경(Cho, Hye-Kyung) 한국체육과학회 2021 한국체육과학회지 Vol.30 No.2

This study was conducted as an experimental study for people with spinal cord disabilities to find out the impact of Presence on immersion and sports involvement due to sports virtual reality (VR) experiences. So we selected 33 people with spinal cord disabilities as the population, and we use SPSS 21.0 for data processing. Frequency analysis, factor analysis, reliability analysis, correlation analysis, and multiple regression analysis were used, and the following conclusions were drawn based on the results. First, the factors of realism and mobility among the factors of Presence caused by sports virtual reality experience had a positive effect on the factors of immersion. Second, among the factors of Presence caused by sports virtual reality experience, the factors of realism and self-esteem had a positive influence on the factors of sports involvement (cognitive). Third, among the factors of Presence caused by sports virtual reality experience, the factors of realism, self-reliance and self-esteem had a positive influence on the factors of sports involvement (behavioral). Fourth, the immersion caused by the sports virtual reality experience had a positive effect on the factors of sports involvement (cognitive). Fifth, immersion due to the sports virtual reality experience had a positive effect on sports involvement (behavioral) factors.