난소 및 난소 종양 염전의 초음파 소견

오연희,이현경,이원재,이성우,박수성,윤혜원,임문환,심재철,김용탁,김성숙,김정란 동국대학교 경주대학 1993 東國論集 Vol.12 No.-

Acute torsion of the ovary and ovarian mass is a recognized surgical emergency, but rarely has the diagnosis been made preoperatively on the basis of imaging studies. The sonographic findings in 14 cases of surgically proven torsion of the ovary and ovarian mass are described. Mostly cystic ovarian mass, engorged vessel, dilated uterine tube, beak-like echo(torsion site), smooth mass wall thickening an free-fluid collection in cul-de-sac are described. More significant in terms of specificity were the demonstration in 6 cases(42.9%) of the smooth mass wall thickening and in 8 cases(57.1%) of a free fluid in the cul-de-sac. We report the sonographic findings of ovary and ovarian mass torsion that may suggest the preoperative diagnosis of this condition.

한라산 주변에 발생하는 Karman Vortex Street 재현

권지혁(Kwon Ji-hyuk·Lee),이연원(Lee Yeon-won),김영덕(Kim Young-duk),박광열(Park Kwang-yul) 한국풍공학회 2006 한국풍공학회지 Vol.10 No.1

늦가을과 초본 사이 제주도 후면에 Karman vortex street가 발생한다. 이러한 vortex가 발생하기 위해서는 기온 역전층과 5 ~ 13 m/s의 지속적인 바람이 필요하다는 것을 밝히기 위한 많은 연구들이 있었다. 이러한 vortex clouds는 발생 후 주 풍향의 방향을 이동하게 된다. Karman vortex street는 기상학에서 매우 흥미로운 주제이다. 본 연구에서는 LES 난류 모델을 이용하여 Karman vortex street에 관한 해석을 수행하고 수치해석을 통해 얻은 결과와 기상 데이터가 일치함을 보였다. From late autumn to the beginning of the spring, the phenomena of the Karman vortex street have been frequently observed in the wake of Mt. Halla in the Jeju island. Some researches revealed that the necessary conditions for development of these vortex clouds are a strong low-level inversion of temperature and a persistent wind speed of 5 to 13m/s. After the cloud is formed, the vortex clouds are shed from alternating sides of Jeju island and then move downwind with main airflow stream. The Karman vortex street in the wake of the Jeju island was one of the interesting topics in meteorology. In this study, CFD using LES turbulence model was developed to investigate the Karman vortex street and the results of CFD showed a good agreement with weather data.

Genetic Characterization of Haemagglutinin 1 Domain of Influenza B Viruses Isolated in Korea during $1988{\sim}1999$

Shin, Gu-Choul,Na, Byoung-Kuk,Lee, Joo-Yeon,Ahn, Jung-Bae,Park, Jong-Won,Lee, Jin-Soo,Kim, Jee-Hee,Kim, Woo-Joo,Kang, Chun The Korean Society for Microbiology 2003 Journal of Bacteriology and Virology Vol.33 No.4

Although Korean influenza virus isolates have been genetically associated with the vaccine strains of the corresponding year, influenza B viruses have prevailed almost every year in Korea during the past decades. We have 'analyzed the genetic characteristics and evolutionary patterns of the haemagglutinin (HA) 1 domains of influenza B viruses isolated during 1988-1999 using direct RT-PCR and sequencing. Phylogenetic analysis of influenza B viruses isolated in Korea indicated that antigenically and genetically distinguishable strains of the lineage II and lineage III variants had been cocirculated. Variants prevailed in early 1990s are represented in 1996/97 and 1998/99 and some different variants have been co circulated geographically and prevailed concurrently in Korea. All HA1s of Korean isolates have amino acid substitutions mainly in the region between position 124 and 310, which was previously proposed an immunodominant region. Insertion-deletion patterns of the HA gene revealed that Korean influenza B viruses were evolved from Lee40 with different manner between lineage II and III viruses. Lineage III viruses were also divided into two groups as conserved group and inserted group, in relation to Lee40. But lineage II viruses had evolved with directional pattern. Antigenic index proposed that influenza B isolates prevailed since 1996/97 seasons might had emerged from the antigenic variants of a Seo1697-like virus and that new variants might appear from the lineage II viruses resulting in persistent prevalence in Korea.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

Agrobacterium tumefaciens를 이용한 bialaphos 저항성 형질전환 벼의 개발

이효연,이춘환,김호일,한원동,최지은,김진호,임용표 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

비선택성 제초제인 bialaphos는 고등식물에 있어서 glutamine 합성을 억제하여 식물체를 고사시킨다. Acetyltransferase에 의해 encoding된 bialaphos 저항성 유전자는 세균 Streptomyces hygroscopicus SF1239로부터 cloning된 것을 사용하였다. Bialaphose 저항성 유전자를 Agrobacterium 감염법을 이용하여 국내에서 재배되는 벼(동진)에 도입한 결과 약 30%정도의 형질전환 식물체를 얻을 수 있었다. T_1세대의 17개체는 hygromycin과 bialaphos에 대한 저항성 유전형질이 3 : 1로 분리되었다. 또한 Southern 분석을 실시한 결과 wild type의 식물체에서는 Bar 유전자의 검출을 볼 수 없었으나 형질전환 식물체의 경우 Bar 유전자의 검출이 가능하였다. T_3 세대의 형질전환 식물체와 wild type의 식물체를 포장상태에서 비선택성 제초제인 바스타를 살포하고 3주 후에 관찰한 결과 형질전환 식물체는 외형적으로 아무런 피해를 받지 않고 정상적으로 생장하였으나, wild type의 식물체와 잡초는 모두 고사하였다. 이상의 결과를 종합해보면 hygromycin과 bialaphos 저항성 유전자는 Agrobacterium 감염법을 이용하여 단자엽 식물인 벼에 도입할 수 있다는 것을 보여준 것이며, 또한 bialaphos 저항성 유전자가 식물에 도입됨으로써 비선택성 제초제에 대한 저항성 식물을 개발 할 수 있다는 것을 보여 주었다. The bialaphos is a potent inhibitor of glutamine synthease in higher plants and is used as a non-selective herbicide. We have used the bialaphos resistant gene (Bar) encoding for an acetyltransferase isloated from Streptomyces hygroscopicus SF1293. Callus derived from mature seeds of rice (Oryza sativa L. cv. Dong Jin) were co-cultivated with Agrobacterium tumefacieus EHA101 carring a plasmid pGPTV-HB containing genes for hygromycin resistance (HygR) and Bar. Transgenic plants showing in vitro resistance to 50 mg/L hygromycin and 10 mg/L bialaphos were obtained by using a two-step selection/regeneration procedure. Transformation efficiency of rice was about 30% which was as high as reported in other dicotyledons. Progenies (T_1 generation) derived from primary transformant of 17 lines were segreagated with a 3 resistant:1 sensitive ratio in medium containing hygromycin and bialaphos. Stable integration of Bar gene into chromosomal DNA was proven by Southern blot analysis of genomic DNA isolated from T_2 progenies. Transgenic plants (T_3) grown in the field were resistant to bialaphos (Basta) at a dosage lethal to wild type plants.

하악 대구치에서 근관세척방법에 따른 잔사제거효과에 대한 평가

이소영,손원준,이우철,금기연,배광식,백승호 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.3

본 연구의 목적은 isthmus가 존재하는 하악 대구치의 근심 근관에서 근관세척방법에 따른 잔사제거효과를 평가하는 것이다. 45개의 하악 대구치의 근심근관을 #30 Profile .06까지 확대하였다. 각 근관을 3개의 군으로 나누고 conventional irrigation syringe와 초음파, RinsEndo를 사용하여 1분간 최종 세척하였다. 조직표본을 제작한 후, 광학현미경으로 치근단 1, 3, 5 mm 부위의 단면을 관찰하였다. 근관과 isthmus의 잔사 양으로 청결도를 계산하고 Mann-Whitney U test로 검정하였다. 1. 초음파 군과 syringe 군은 5 mm 부위의 isthmus를 제외한 나머지 부위에서 청결도의 유의한 차이가 없었다. 2. RinsEndo군은 syringe 군에 비해 1 mm, 3 mm 부위의 근관과, 모든 부위의 isthmus에서 유의하게 높은 청결도를 나타내었다(p<0.05). 3. 초음파 군과 RinsEndo 군은 3 mm 부위의 근관을 제외한 나머지 부위에서 청결도의 유의한 차이가 없었다. 임상적으로 RinsEndo를 이용한 근관세척방법의 부가적인 적용이 하악 대구치의 근심근관의 잔사제거에 효과가 있을 것으로 사료된다. The aim of this in vitro study was to evaluate the cleaning efficacy of various irrigation methods in the mandibular mesial roots. The forty five mesial root canals were shaped by Profile .06 instruments to apical size #30 and irrigated with 5 ml of 3.5% NaOCl. The teeth were divided into 3 groups and irrigated finally for 1 minute; Group 1: syringe irrigation, Group 2: ultrasonic irrigation, Group 3: RinsEndo irrigation. After histological processing, the cross sections of apical 1, 3, and 5 mm level were examined with an optical microscope. The cleanliness values of canals and isthmuses were calculated and analyzed by Mann-Whitney U test. 1. There were no significant differences in both canal and isthmus cleanliness between syringe irrigation and ultrasonic irrigation except 5 mm level of isthmus. 2. RinsEndo irrigation had significantly higher canal cleanliness values than syringe irrigation at 1 mm and 3 mm levels (p<0.05). Also, RinsEndo irrigation had significantly higher isthmus cleanliness VaIues than syringe irrigation at all levels evaluated (p<0.05). 3. There were no statistical differences in both canal and isthmus cleanliness between ultrasonic irrigation and RinsEndo irrigation except 3 mm level of canal. From this study, RinsEndo irrigation can be useful as an additional irrigation procedure.

8.3% Carbamide Peroxide 함유 펜 형 자가미백제인 BIancTis Forte의 색조개선 및 안전성에 관한 임상연구

이진경,민선홍,홍성태,오소람,정신혜,황영혜,유성엽,배광식,백승호,이우철,손원준,금기연 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.2

This clinical study evaluated the whitening effect and safety of polymer based-pen type BlancTis Forte(NIBEC) containing 8.3% carbamide peroxide. Twenty volunteers used the BlancTis Forte whitening agent for 2 hours twice a day for 4 weeks As a control. Whitening Effect Pen (LG) containing 3% hydrogen peroxide was used by 20 volunteers using the same protocol. The change in shade (ΔE^(*) color difference) was measured using Shadepilot™ (DeguDent) before, during and after bleaching (2 weeks, 4 weeks and postbleaching 4 weeks). A clinical examination for any side effects (tooth hypersensitivity or soft tissue complications) was also performed at each check-up. The following results were obtained. 1 Both the experimental and control groups displayed a noticeable change in shade (ΔE) of over 2 No significant differences were found between the two group (p>0.05) implying that the two agents have a similar whitening effect. 2 The whitening effect was mainly due to changes in a and b values rather than in L value (brightness). The experimental group showed a significantly higher change in b value thus yellow shade than the control(p < 0.05) 3 None of the participants complained of tooth hypersensitivity or soft tissue complications confirming the safety of both whitening agents 8.3%의 carbamide peroxide를 함유한 펜형 코팅용 미백제인 BlancTis Forte (NIBEC, Seosul & JinCheon)를 실험군으로, 3% hydrogen peroxide를 함유한글 Whitening Effect Pen (LG. Seoul) 제재를 대조군으로 각각 피험자 20명에게 2시간씩 1일 2회 제조사의 지시대로 치아표면에 4주간 적용하도록 지시하고 색조개선 효능과 안전성을 평가하였다. 미백 효과는 미백 전 및 미백 2주, 4주 및 미백 종료 4주 후에 Shadopilot™을 이용하여 색 변화를 측정하였고, 매 내원시기마다 모든 환자는 치수생활력 검사와 치주 및 치태 검사를 통해 부작용 여부 (치아과민증 및 구감 내 연조직의 부작용)를 기록한 후 다음과 같은 결과를 얻었다. 1.실험군 및 대조군의 색 변화량 (ΔE)은 2이상으로 인지할 수 있는 색 변화를 보였으며, 두 제품 간에는 통계적으로 유의한 차이를 보이지 않아 (p > 0.05) 유사한 미백효능을 나타냄을 알 수 있었다. 2,미백효과는 명도의 개선보다는 주로 a. b값의 변화에 의한 것으로 특히 실험군에서 b값의 변화, 즉 황색조의 개선효과가 대조군에 비해 유의성 있게 높은 것으로 나타났다 (p <0.05). 3.치아나 치은의 과민증이나 이상증상을 호소하는 피험자는 없어 두 제품 모두 안전성을 확인할 수 있었다.

개량제 종류 및 혼합조건이 탈수특성에 미치는 영향

李元鎬,元聖淵 충주대 산업과학기술연구소 1999 産業科學論文集 Vol.7 No.2

본 연구에서는 슬러지의 탈수효율을 증대시키기 위한 슬러지 개량시 물리 ·화학적 인자들의 영향을 검토하였다. CST는 슬러지의 탈수성을 측정하기 위한 유용한 도구로 기존 탈수성 측정 방법인 SRF와 상관성이 높아 간단하며 신속하고 경제적인 측정이 가능하였다. 바닷물로 응집된 슬러지는 pH가 중성으로 조정되는 경우 슬러지 입자가 해체되어 재결합하기 위해 요구되는 화학약품 요구량은 증대되었다. 탈수 공정에서 혼합은 매우 중요하며 혼합에 의해 슬러지 입자의 크기가 증대 되었다. 하지만, 매우 큰 혼합강도 및 시간에서는 응집물이 파괴되었다. 양이온성 개량제의 이용시 최적 혼합조건은 약 20,000(Gtd)이하에서 관찰되었으며, 슬러지의 성상 및 개량제 주입량에 따라 차이를 보이고 있다. 바닷물 응집 슬러지의 최적 혼합조건은 개량제의 충분 조건에서는 20,000-100,000이었다. 이는 개량제의 충분 조건이 충분치 못한 조건에서 보다 전단력이 증가되었음을 의미한다. 또한 미세 입자가 증가된 조건에서는 최적 혼합 조건이 50,000-300,000으로 증가되었다. 따라서 혼합 조건은 슬러지 탈수를 위한 개량시 중요한 인자이며, 슬러지 개량은 최적의 혼합조건에서 운영함이 바람직하다. In this study, the effect of physo-chemical variables on sludge conditioning of waste sludge was determined to enhance dewaterability of sludges. The Capillary Suction Time (CST) apparatus was observed to provide the first simple, rapid, and inexpensive means for measuring the dewaterability potential of wastewater sludge. Good correlation was also observed between CST and the specific resistance to filtration(SRF). The dewaterability of seawater flocculated sludge was deteriorated with pH adjustment to neutral. pH adjustment of seawater flocculated sludge seems to cause disaggregation of sludge particles, which increase demand for chemicals that recoagulate the fractured aggregates. The mixing characteristics of both the condition and dewatering steps seem to be important in the optimization of the sludge dewatering process. Mixing enhanced initially to increase particle size. However, floc particles were breakup with high mixing intensity and mixing duration. Optimum Gtd values for the seawater flocculated sludge was below 20,000 with use of cationic polyeletrolytes. Optimum Gtd values were varied with dosage of sludge conditioner with sufficient dosage of sludge conditioner With sufficient sludge conditioner, Optimum Gtd value for seawater flocculated tannery sludge ranged from 20,000 - 100,000. This indicates that sludge strength with sufficient dosage of sludge conditioner was enough to stand higher shear force than that with insufficient dose. Also, it was found that optimum Gtd values were significantly increased for dewatering deflocculated sludge of fine particles. In this case, optimum Gtd was ranged from 50,000 - 300,000. Since Gtd was important parameter to improve the dewaterability of conditioned sludge, sludge conditioning process should be operated at optimum range of Gtd.

일부 한국인의 혈청 ceruloplasmin 정상 참고치 설정 및 질환별 비교 : Comparison of Its Level among Various Diseases

이동수,박애자,박정덕,장임원,홍연표 중앙대학교 의과대학 의과학연구소 1999 中央醫大誌 Vol.24 No.1

Ceruloplasmin has been investigated as one of the useful biologic index for early diagnosis of atherolsclerosis. However, there was no normal reference value taking into account the confounders in Korea. This study was performed to estimate the normal reference values and present the confounders of ceruloplasmin. Also we compared of serum ceruloplasmin levels among normal reference group and three abnormal groups: 475 healthy subjects, 53 liver dysfunctions, 72 positive test of chronic inflammatory diseases, and 89 hypercholesterolemias. Mean serum ceruloplasmin level of healthy subjects were 41.6±7.6㎎/㎗ in males and 42.1±7.2㎎/㎗ in females, respectively. It was tend to increase of ceruloplasmin by age in both sexes. However, the statistical difference was not found by age group between both sexes. Statistically significant correlations were found between serum ceruloplasmin and age, body mass index(BMI), white blood cell(WBC) and triglyceride(TG) in males and age, BMI, WBC and total cholestrol(TG) in females. After adjustment for age, BMI,WBC and TG in males and age, BMI, WBC and TG in females, significant elevations of serum ceruloplasmin were found in liver dysfunction(p=0.0077) and positive test of chonic inflammatory disease(p=0.0217) in males and in oisitive test of chronic inflammatory disease(p=0.0023) and hypercholestolemia(p=0.0124) in females relative to healthy reference subjects. There is no statistical difference among liver dysfunction, postive test of chronic inflammatory disease, and hypercholesterolemia.

HBsAg양성 원발성간암에 있어서 HBV-DNA표지자의 PCR성적

이원길,김재식,김정철,서장수,강은자,이중원,김기연,송경은,양정선 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

목적 : HBV-DNA를 정성적 그리고 정량적으로 검출함으로써 강한 전염성과 높은 유병율로 인해 사회적으로 문제가 되는 B형 간염과 원발성간암의 연관성을 알아보고자 하였다. 대상 및 방법 : B형 간염 표면항원(HBsAg)이 양성을 보이는 원발성간암 환자 38명을 대상으로 하였으며 HBV-DNA 중합효소연쇄반응법을 이용하여 정성적 검출 그리고 luminometry법을 이용하여 정량적 검출을 하였다. 결과 : HBV-DNA 중합효소연쇄반응법과 luminometry법의 양성율은 각각 57.9%, 39.5%를 보였다. 그리고 HBsAg과 HBeAg가 동시에 양성을 보인 11명에서는 HBV-DNA 양성율이 81.8%를 보였다. 결론: HBV-DNA 중합효소연쇄반응법의 양성율이 luminometry법에 의한 양성율보다 높은 결과를 보였고 HBV-DNA 검사는 B형 간염을 조기 발견하고 치료하여 만성간질환으로의 진행을 예방하고 특히 원발성간암의 병율을 낮추는데 많이 기여할 것으로 사료되었다. Background : Primary hepatocellular carcinoma(PHCC) is the most common malignant neoplasm in most countries of Asia and Africa. Hepatitis B virus is known to be strongly related to the pathogenesis of PHCC. HBV-DNA PCR and HBV-DNA quantitation assay were attempted to apply to 38 cases of HBsAg positive PHCC. Methods : The ordinary HBV markers(HBsAg, anti-HBs, anti-HBc(Ig-G and -M), HBeAg and anti-HBe) were examined with ELISA. Qualitative screening of HBV-DNA PCR and HBV-DNA quantitation-luminometric measurement were performed. Results : Among 38 cases of HBsAg positive PHCC, positive rates for HBV DNA-PCR and HBV DNA-quantitation were 57.9% and 39.5%, respectively. And 11 cases which were positive for both HBsAg and HBeAg showed 81.8% positive rate in HBV-DNA PCR. Conclusion : For 38 cases of HBsAg positive PHCC, the positive rate for HBV DNA-PCR was higher than HBV-DNA quantitation-luminometry. In HBV-DNA PCR, both HBsAg and HBeAg positive cases showed high positive rate.