서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Kim, Se-Jin,Ho Hur, Joon,Park, Channy,Kim, Hyung-Jin,Oh, Gi-Su,Lee, Joon No,Yoo, Su-Jin,Choe, Seong-Kyu,So, Hong-Seob,Lim, David J,Moon, Sung K,Park, Raekil Nature Publishing Group 2015 Experimental and molecular medicine Vol.47 No.2

<P>Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice. Cisplatin increases the catalytic activity of caspase-3 and caspase-8 proteases and the production of free radicals, which were significantly suppressed by pretreatment with bucillamine. Bucillamine induces the intranuclear translocation of Nrf2 and thereby increases the expression of γ-glutamylcysteine synthetase (γ-GCS) and glutathione synthetase (GSS), which further induces intracellular antioxidant glutathione (GSH), heme oxygenase 1 (HO-1) and superoxide dismutase 2 (SOD2). However, knockdown studies of HO-1 and SOD2 suggest that the protective effect of bucillamine against cisplatin is independent of the enzymatic activity of HO-1 and SOD. Furthermore, pretreatment with bucillamine protects sensory hair cells on organ of Corti explants from cisplatin-induced cytotoxicity concomitantly with inhibition of caspase-3 activation. The auditory-brainstem-evoked response of cisplatin-injected mice shows marked increases in hearing threshold shifts, which was markedly suppressed by pretreatment with bucillamine <I>in vivo</I>. Taken together, bucillamine protects sensory hair cells from cisplatin through a scavenging effect on itself, as well as the induction of intracellular GSH.</P>

인터넷 캐쉬를 위한 멀티미디어 데이터의 재배치 정책

홍현옥,임은지,박성호 동의공업대학 2000 論文集 Vol.26 No.1

Through the dramatic growth of Internet, it becomes easy for people to access geographically distributed vast amounts of information. But, currently Internet is suffering from problems such as server overload, network congestion and client response time. In addition, currently the number of continuous media data such as audio and video is growing rapidly. In this paper, we propose SCU(Smallest Caching Utility) proxy caching scheme that stores a portion of continuous media stream or entire stream on the Internet. The proposed scheme reduces client latency and maximizes the amount of data served directly from cache without accessing the central server. By caching the initial fraction of stream data, service startup latency can be reduced. And, by varying the size of the fraction of stream to be cached according to variation of stream popularity, we can utilize the cache space efficiently and maximize the amounts of data served directly from cache. We use the caching utility formula of each stream for the measurement of cache replacement. The way to measure popularity of continuous media stream should be different from that of traditional data such as text and image. We propose the method of measuring popularity of stream using the amounts of data played by clients. We have performed simulations to evaluate our caching policy, Simulation results show that our caching policy outperforms other caching algorithms such as LRU, LFU and SIZE in aspects of BHR(byte hit ratio), initial latency and replacement overhead.

보행시 하지체질의 내적일 분석

홍성표,이순호,김희수 忠南大學校體育科學硏究所 1995 體育科學硏究誌 Vol.13 No.1

This study is to represent basic data of biomechanical work of human body which has been data measured precisely and is to see on pathology and abnormal gaits patterns. And 5, 6th grade boys in Taejon city were attended in this experiment. Each student wore 8 landmarks on their lower leg joints and walked for 4 Km/h, 5 Km/h, and 6 Km/h on the treadmill Mechanical energy of lower extremity segment by lower joint (thigh and shank) movement were measured in stance phase and swing phase which were assessed internal work and energy of segment The conclusions were as following; 1. Increasing gait velocity cause toe off in early stage and swing of lower extremity happen early and quickly with angle of shank increasing in swing phase. 2. Children gait velocity grow rapidly above 5km/h, internal work of thigh mechanical energy showed value of work clearly and large. and internal work change represent greater in shank than in thigh 3. The stance period of gait is the period off set by two operated cocontracting muscles, and the later the speed of gait is, the lower the effect of the net torque.

프라이버시권에 있어서의 個人情報保護에 관한 硏究

洪性讚,黃寅豪 건국대학교 사회정책연구소 2001 사회과학연구 Vol.14 No.1

간질발작후 MRI 영상에서 뇌 종창을 보인 3예 보고

홍현숙,김대호,이혜경,박재성,박성진,조준희,차장규,백상현 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

We report seizure induced brain swelling in three patients. MRI revealed a cortical, subcortical(3/3), and basal ganglia(2/3) high signal intensity on T2- weighted and FLAIR images. The lesion shows low signal on T1-weighted image, and enhanced after contrast administration. Follow up study after 27 days in one case revealed complete resolution of the lesion. The reversible MRI findings may be the results of a local brain swelling, breakdown of blood-brain permeability, and a defect of cerebral autoregulation during seizure activity. The transient nature of such findings have to be considered in the differential diagnosis such as reversible ischemia, migraine, inflammation and infection.

소아에서 발생한 골수이형성 증후군 2례

홍성진,윤석중,김성우,조형구,오명호,김기혁,이인성 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Myelodysplastic syndrome(MDS) is a group of acquired conditions characterized by progressive bone marrow failure associated with normocellular or hypercellular bone marrow that cannot be attributed to nutritional deficiency, chronic infection, or other chronic systemic illness, and cannot be reversed by the successful treatment of those conditions. Whereas the cases of secondary MDS occur at all ages, primary MDS is essentially a disease of elderly, though no age group is exempt and predomonant in men. The MDS is fundamentally clonal disorders at the level of the haemopoietic totipotent stem cell. Clinically, they are characterized by varing degrees of peripheral cytopenia(s) with morphological and functional abnormalities of blood elements. We have experienced two unrelated pediatric cases, who showed pancytopenia on admission and the characteristic marrow findings of MDS. The first case, a 12 months-old girl, showed increased reticulin with abnormal localization of immature precursor cells(ALIP) in her bone marrow, in addition to dysplastic features such as bi-and multi-nucleation of late normoblasts and internuclear bridging. She also showed 22% of blasts in her bone marrow cells thus classified in the category of RAEB-t after FAB classification. Also found were a chromosomal abnormality namely 46 XX t(14q21q), which was an unusual one. Her family brought her home and, 4 month later, she deceased. The second case, a 12 year-old boy, showed pancytopenia with Pseudo-Pelger-Huet anomaly in neutrophils but no blasts in the peripheral blood. Bone marrow of this case also showed the picture of dyserythropoiesis with binuclearity, internuclear bridging, nuclear fragments, multinuclearity of late normoblasts, in addition to megaloblastoid change in the normoblasts and increased mitosis in granulocytic series. No chromosomal abnormality was found. Classified as RA after FAB classification of MDS. Showed good response to conservative management for anemia for more than one year.

진동감쇠 장치를 부착한 트레일러의 3축진동

홍종호,이성범,김성엽 한경대학교 2003 論文集 Vol.35 No.-

This study was aimed to find out the basic information for reducing damage of agricultural products during transportation. The vibration absorption system, consisted of suspension at wheel mounting and coil spring & rubber at hitch part, was developed and tested for the vibration characteristics. The 3-dimensional acceleration levels were measured at engine and trailer part according to the low(500rpm), medium(1000rpm), and high(1200rpm) engine speed. The results of this research could be summarized as follows; (1) For low engine speed of 500rpm, the average accelerations of engine part were 0.0085 m/s², 0.0238m/s². and 0.0182 m/s² for X-, Y-, Z-direction, respectively. Those of trailer part were 0.0162 m/s², 0.013 m/s². and 0.0l06 m/s² for X-, Y-, Z-direction respectively. And the peak accelerations of trailer part were 0.19 m/s², 0.34 m/s², and 0.18 m/s² for X-, Y-, Z-direction, respectively at 80Hz of frequency. (2) For medium engine speed of 1,000rpm, the average accelerations of trailer part were 0.0164 m/s², 0.011 m/s². and 0.0104 m/s² for X-, Y-, Z-direction, respectively. And the peak accelerations were 0.31 m/s² at 100Hz, 0.29 m/s² at 70Hz, and 0.28 m/s² at 100Hz for X-, Y-, Z-direction, respectively. (3) For high engine speed of 1,200rpm, the average accelerations of trailer part were 0.0293 m/s², 0.0194 m/s². and 0.022 m/s² for X-, Y-, Z-direction, respectively. And the peak accelerations were 1.2 m/s², 1.1 m/s², and 1.9 m/s² for X-, Y-, Z-direction, respectively at 60Hz of frequency. (4) For the driving of power tiller at speed of 0.35m/s on the controlled road, the average accelerations of trailer part were 0.018 m/s², 0.031 m/s². and 0.027 m/s² for X-, Y-, Z-direction, respectively. And the peak accelerations were 0.13 m/s², 0.24 m/s², and 0.29 m/s² for X-, Y-, Z-direction, respectively.

미국의 씬시내티 정수장에 대하여

홍성호 대한상하수도학회 2002 상하수도학회지 Vol.16 No.3

CMP 폐액의 고액분리에서 응집제의 영향에 관한 연구

홍성호,오석환 대한상하수도학회 2002 상하수도학회지 Vol.16 No.2

A coagulation was applied to separate the solid and liquid from waste CMP generated from the CMP process. Three different coagulants - PACl, MgCl_2 and Ca(OH)^2 was used to find the best coagulant and optimum condition of each coagulant for water and solid recovery. When the solid content was 0.lwt%, the adequate flocculation speed was 10 to 30 rpm for PACl. However, the flocculation speed was not critical for MgCl_2 and Ca(OH)_2 at any dosage. Minimum sedimentation time was 30 minutes to get less than 1NTU of turbidity, the sludge volume was 10 to 15% and 50 to 55% for 0.1wt% and 0.5wt% of waste CMP slurry, respectively. According to the experimental results such as turbidity, zeta potential and heavy metal concentration in the supernatant PACl was the best coagulant for water recovery.