급성기 뇌경색 환자에서 화열 관련 증상과 증후의 변화에 관한 연구

곽승혁,박수경,우수경,이은찬,박주영,정우상,문상관,조기호,조승연,박성욱,고창남,Kwak, Seung-hyuk,Park, Su-kyung,Woo, Su-kyung,Lee, Eun-chan,Park, Joo-young,Jung, Woo-sang,Moon, Sang-kwan,Cho, Ki-ho,Cho, Seung-yeon,Park, Sung-wook,Ko, Ch 대한중풍순환신경학회 2011 대한중풍.순환신경학회지 Vol.12 No.1

Objective : Fire and heat related symptoms and signs are considered common in acute stage of diseases. The purpose of this study is to evaluate the occurrences and changes of fire and heat related symptoms and signs in acute cerebral infarction patients. Method & subjects : 40 acute cerebral infarction patients hospitalized in Oriental medicine hospital, Kyung-Hee University, who had examined and diagnosed 2 or 3 times based on oriental medical diagnosis were selected. We chose 23 as fire and heat related symptoms and signs from 94 diagnostic articles, and we added all those scores together of each patient. We analysed the scores of fire and heat related symptoms and signs as the time passed, and depending on oriental medical diagnosis. Result : In acute cerebral infarction patients of this study, 4 of fire and heat related symptoms and signs were took 1st, 2nd, 4th and 8th places in most changeable 10 articles of total 94 articles. The mean score of fire and heat related symptoms and signs of all patients were decreased significantly over the 3 times of measurements. The 8 patients diagnosed as fire and heat diagnosis at visit1 were samely diagnosed as fire and heat diagnosis at visit2, and at visit3 5 patients of them except for 3 patients excluded between visit2 and visit3, were still diagnosed as fire and heat diagnosis. At all of 3 measuring times, the scores of fire and heat related symptoms and signs of fire and heat diagnosis group were higher than non-fire and heat diagnosis group. Conclusion : This study indicated that fire and heat related symptoms and signs were very changeable phenomenon in acute cerebral infarction patients. And they decreased as time goes on.

우리나라 기업의 기술도입 특성에 관한 실증적 연구 : 미국과 일본의 기술을 중심으로 Import by Korean Firms from U.S and Japan

문희철,송우용,황경연 충남대학교 경상대학부설 경영경제연구소 1996 경영논집 Vol.12 No.1

항정신병약물을 처음으로 사용하는 초발 정신증 환자에서 나타나는 체중 및 대사성 지표의 변화 : 후향적 연구

김우진,심주철,공보금,강제욱,문정준,김정은,김민걸,박민경,김성진,김현정,정도운 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2

Objectives:This study was to identify weight & metabolic changes in first-episode psychotic patients with antipsychotics use and investigate the differences of weight & metabolic changes between first-episode psychotic patients and controls with antipsychotics use. Method:In this retrospective study, twenty eight first-episode psychotic patients and twenty eight controls with schizophrenia, schizoaffective or bipolar disorder defined by DSM-IV criteria were included. Information about demographic and clinical characteristics of the subjects was gathered from the medical records. Also body weight, sBP, dBP, fasting glucose, lipid profile and WBC count were evaluated before and after antipsychotics use. Rogistic regression was conducted to assess factors associated with weight gain. Results:First-episode psychotic patients showed more weight and BMI changes than controls after antipsychotics use, and these changes continue over 12 months. On the other hand, there were no significant factors associated with weight gain. Conclusion:The results of present study suggest that antispychotics is one of the major causes inducing weight gain of psychotic patients and antipsychotics-induced weight gain is more vulnerable to drug-naive first-episode psychotic patients.

Interleukin-1β에 의한 사람 정상 코점막 상피세포의 분비기능 및 형태 변화

김경수,윤주헌,최진우,이정권,문형진,박준호,전희선 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.11

중이, 외이도 및 측두하와에 국한된 편평상피유두종 1예

윤병문,박성원,민경식,홍기수,조미연,양석우 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.7

운동종목에 따른 운동선수의 영양필요량 및 기호성에 준한 표준 식단의 컴퓨터 입력 프로그램 개발방법에 관한 연구

문수재,손경희,이동우,이영미 연세대학교 대학원 1986 延世論叢 Vol.22 No.1

본 연구는 각종 운동선수 대상의 설문조사를 기초로 하여 운동선수의 식생활 관리를 위한 전산화 프로그램을 제시하였다. 즉 1) 운동선수의 식기호를 통한 요구와 체급의 필요에 준한 각종 식단작성과 급식관리를 위한 전산화 프로그램을 작성하였다. 2) 이에 근거를 둔 영양상담 프로그램을 개발하기 위한 기초자료의 정리를 시도하였다. 기초자료 수집을 위해 실시한 16종목의 운동선수 232명을 대상으로 실시한 기호도 및 생활유형 분석조사의 결과는 대부분의 운동선수가 ① 규칙적인 생활을 하고 있었으며, 일일생활의 구성은 취침(7~8시간), 아침식사전 운동(1~1 1/2시간), 오전운동(2~3시간), 오후운동(2 1/2~3 1/2시간), 식사 및 휴식(5~7시간), 자유시간(1~3시간)으로 구성되어 있으며, ② 현재 식생활의 문제점은 단체급식시 급식시 제공되는 음식의 맛, 질적수준, 3끼 음식 분배량의 부적절성, 경기직전에 식사의 지나친 감량이나 증량을 지적하였다. ③ 조사대상으 88%가 장기적인 식사관리가 필요하다고 지적했으며, 경기력 향상을 위해 특별히 처방된 식사를 하는 선수는 전체의 43.5%로 처방식의 주종은 육류(단백질식품), 야채(비타민, 무기질식품), 그 이외 열량농축식품(지방, 캔디류)으로 구성되어 있었다. 처방식을 가지고 있는 주요 이유는 영양섭취를 개선시킴으로써 경기력 및 체력향상과 운동시에 condition조절이 가능하다는 점을 지적하였다. ④ 식품에 대한 기호성 조사에서는 대부분의 식품에 대해 극히 싫어하거나 기피하는 문제점은 없었다. 컴퓨터를 이용한 운동선수 대상의 식생활관리 프로그램 개발을 위해서 사용한 기기는 IBM-PC OA-16XT기종의 Personal computer였으며, 이 기기에서 이용가능한「Basic language」,「lotus」system, 「DBASE Ⅲ」를 이용하여 프로그램을 작성하였다. 프로그램 작성을 위해 선행한 연구로 ① 설문조사를 통하여 운동선수의 생활유형을 분석하여, 각 운동종목별 영양필요량 산출을 시도하였고, ② 한끼에 1,200Kcal를 공급할 수 있는 식단을 영양학적, 식품학적 견지에서 작성하였으며, ③ 식품별 자료처리가 용이하도록 식품교환단위의 설정 및 음식에 고유 번호를 부여하는 작업을 실시하였다. 프로그램은 ① 일일 섭취한 영양가 평가하는 프로그램 ② 운동종목, 체중, 성, 생활시간을 고려한 일일 필요 영양소량을 계산하는 프로그램 ③ 변화있고 다양한 식단작성 및 Recipe 제시 프로그램을 개발하였다.

Helicobacter pylori가 만성위염과 위종양에 미치는 영향에 관한 면역조직화학적 밑 초미세구조적 연구

문경래,정순봉,이미숙,이미자,서재홍,김만우,박찬국 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Helicobacter pylori (H. pylori) is accepted as a principal cause of chronic gastritis and an important factor in the pathogenesis of peptic ulcer and gastric malignancy. The aim of our studies is to investigate relationships between H. pylori and gastric epithelial cells. Materials ðods : One hundred and eighty one H. pylori positive cases of gastric biopsy specimens were studied immunohistochemically and ultrastructurally. Results : p53 positive staining exhibited foveolar epithelial hyperplasia in 1 out of 32 cases, regeneration in 2 out of 12 cases, incomplete intestinal metaplasia in 5 out of 41 cases, complete intestinal metaplasia in 3 out of 18 cases, chronic ulcer in 1 out of 9 cases, tubular adenoma in 2 out of 14 cases and intestinal type of adenocarcinoma in 16 out of 21 cases. Ultrastructurally, H. pylori was observed to be in direct contact with the microvilli of the target cells and was demolishing the surface microvilli. The organisms were in close contact with the uncoated cell membrance. Penetration into the gastric cells by a few organisms was associated with marked cell damage and ultimately to cell disintegration. Conclusion : Our results suggest that H. pylori plays a role in the pathogenesis of gastric cancer, leading a relatively slow, long lasting process that induces chronic active gastritis, intestinal metaplasia, dysplasia, and adenocarcinoma of intestinal type.

마케팅자료에서 특성점들을 이용한 군집방법

문숙경,김우성 한국품질경영학회 2004 품질경영학회지 Vol.32 No.4

We got the growth distance curve by spline smoothing method with observed marketing data and the growth velocity curve by the derivation of the growth distance curve. Using this growth velocity curve, we defined the several characteristic points which describe the variation of marketing data. In this paper, to specify several patterns of marketing data, we suggested characteristic function by using these characteristic points. In addition, we applied characteristic function to the seventeen brands of electric home products data.

간호실무에서 신봉이론(Espoused theories)에 대한 탐색적 연구

서문자,김혜숙,이은희,박영숙,조경숙,강현숙,임난영,김주현,이소우,조복희,이명하,지성애,하양숙,손영희,권성복,김희진,추진아 성인간호학회 2001 성인간호학회지 Vol.13 No.1

As a nursing practice involves nurses' actions in a specific context of health care, this study has focused on exploring the espoused theories in nursing practice within the action science perspectives, Espoused theories are the belief, principles, and rationale expressed by the practitioner as guiding her/his actions in a situation of practice. The data were analysed qualitatively and 25 elements of espoused theories of nursing action were identified and clustered into 6 categories. The 25 elements of espoused theories are as follows: The clinical nurse worked in wholistic and individual nursing, focussed on the patient's needed, comfort and supportive nursing (5 theories of nursing goal) ; excellent skills, knowledge based, assessment and data collection, explaining, educating or a scientific basis(6 theories of nursing intervention): advocacy, value oriented, treatment, account- ability and commitment(4 theories of nursing ethics) ; human respect. partnership, trust(3 theories of patient-nurse relationship) : knowledgable, accumulated clinical experiences and personally lived experiences. positive perspectives(4 theories of nurse), role of intervention. rewarding peer relationship(3 theories of situations) The above mentioned espoused theories are similar to that of nursing textbooks which students learned through basic nursing education and almost the same as the Acts ofa Nurse in Korean. However, we are doubtful whether nurses actually do as they think. Therefore. it is recommended to review the theories-in-use in order to and any discrepancies between the espoused theories and the reality of nursing actions

차아염소산나트륨과 클로르헥시딘의 반응침전물 형성방지를 위한 여러 가지 근관세척 방법의 비교

최문선,박세희,조경모,김진우 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.2

The purpose of this study was to compare the different canal irrigation methods to prevent the formation of precipitate between sodium hypochlorite (NaOCl) and chlorhexidine (CHX). Extracted 50 human single-rooted teeth were used. The root canals were instrumented using NiTi rotary file (Profile .04/#40) with 2.5% NaOCl and 17% EDTA as irrigants. Teeth were randomly divided into four experimental groups and one control group as follows; Control group: 2.5% NaOCl only, Group 1: 2.5% NaOCl + 2% CHX, Group 2: 2.5% NaOCl + paper points + 2% CHX, Group 3: 2.5% NaOCl + preparation with one large sized-file + 2% CHX, Group 4: 2.5% NaOCl +95% alcohol+ 2% CHX. The teeth were split in bucco-lingual aspect and the specimens were observed using Field Emission Scanning Electron Microscope. The percentages of remaining debris and patent dentinal tubules were determined. Statistical analysis was performed with one-way analysis of variance (ANOVA). Energy Dispersive x-ray Spectroscopy was used for analyzing the occluded materials in dentinal tubule for elementary analysis. There were no significant differences in percentage of remaining debris and patent tubules between all experimental groups at all levels (p > .05). In elementary analysis, the most occluded materials in dentinal tubule were dentin debris. NaOCl/CHX precipitate was detected in one tooth specimen of Group 1. In conclusion, there were no significant precipitate on root canal, but suspected material was detected on Group 1. The irrigation system used in this study could be prevent the precipitate formation. 이 실험의 목적은 NaOCl과 CHX의 혼합사용 시, 발생하는 침전물의 형성을 막기 위해 두 용액간의 접촉을 줄일 수 있는 여러 가지 방법을 비교하고, 관찰된 침전물의 원소를 분석하는 것이다. 발거된 50개의 단근치를 사용하였으며 2.5% NaOCl을 이용하여 .04 taper ProFile #40까지 근관형성 하였다. 치아는 다음과 같은 근관세척 방법에 따라 4개의 실험군과 1개의 대조군으로 나누었다; 대조군: 2.5% NaOCl, 1군: 2.5% NaOCl + 2% CHX, 2군: 2.5% NaOCl + paper points + 2% CHX, 3군: 2.5% NaOCl + .04/#45 근관확대 + 2% CHX, 4군: 2.5% NaOCl +95% alcohol+ 2% CHX. 근관세척 후 치아를 양분하고 치관부, 중간부, 치근부 세부위로 나누어 전계 방사형 주사 전자현미경을 통하여 잔사 비율, 개방 상아세관 비율, 상아세관 내 물질의 원소분석을 시행하였다. 실험결과, 실험군 사이에 잔사비율과 개방된 상아세관 비율 비교에서 통계학적으로 유의할 만한 차이는 나타나지 않았다. 1 군의 한 시편에서 C의 함유량이 높게 나타났으며 N과 Cl도 함께 검출되어 para-chloraniline으로 추정되며, 1 군의 다른 시편과 나머지 실험군에서는 O, P, C, Ca의 순으로 함유량이 높은 것으로 나타나 수산화인회석으로 추정된다. NaOCl 세척 후 바로 CHX 세척을 한 군에서 PCA로 의심되는 물질이 검출된 바, 두 용액의 직접적인 접촉을 피하기 위해 주의가 필요하며, 본 실험에 사용된 여러 근관 세척방법 이용 시 침전물의 형성을 예방할 수 있을 것이다.