스포츠 관광 활성화 개선방안에 관한 연구

조충현,김홍식,박은석,강성찬,이동헌 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.1

This study was conducted to investigate the effects of the marketing strategy based on the traditional wrestling, which affects the tour industry. The study used the simple random sampling method in the group of the Kwang-Ju district citizens. The group representatives were directly interviewed, and 277 interviewees replied with concern. The rest of the interviewees were not interested in the survey. The general characteristics of the interviewees -- gender, age, education, job, monthly salary. -- were used to analyze the items related to Sports Tourism in general. Sport Tourism in general Male interviewees had higher recognition over females in the interview. The rate of experience was low for both genders. According to their education, the satisfaction of sport tourism showed low rate. However, there were many answers where the interviewees, not depending on the age or gender, indicated that they will participate in the future. The policy recommended based upon the results of the study is as follows. There is a need for setting up a new strategy in order to increase participation of sports. Also, it is urgent to set up a sports theme center to raise professional sportsmen and to supply them to where they are needed.

Cu-Al-Ni계 형상기억리본의 결정립크기 및 미세조직에 미치는 휠 회전속도의 영향

이영수,이수홍,장우양,강조원 조선대학교 생산기술연구소 2000 生産技術硏究 Vol.22 No.1

To improve mechanical properties of Cu-Al-Ni alloy by the grain refinement, Cu-Al-Ni SMA ribbons were fabricated by melt spinning apparatus. The variations of microstructure, transformation characteristics and mechanical properties with wheel speed were investigated in Cu-Al-Ni SMA ribbons. The ribbons fabricated by melt spinning obtained around 1.5mm in width and 50∼60㎛ in thickness. With increasing wheel speed in order of 10m/s, 15m/s, 20m/s, 30m/s and 35m/s, the grain size was decreased in order of 10㎛, 6㎛, 5㎛, 3㎛ and 3㎛. M_(s) and A, temperatures were decreased with decreasing grain size By X-ray diffraction test, ordered β_1 phase was observed in all the SMA ribbons and the volume friction of it was increased with increasing wheel speed. With increasing wheel speed, strain was increased from 4.8% to 5.8% and fracture mode has changed from mixture of intergranular and dimple fracture to mixture of fiber structure and dimple fracture

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

급성 심근경색 후 심인성쇽의 발생에 관여하는 위험인자

전두수(Doo Soo Jeon),정해억(Hae Uk Chung),승기배(Ki Bae Seung),강동헌(Dong Hun Kang),김상우(Sang Wo Kim),김용주(Young Ju Kim),채장성(Jang Sung Chae),김재형(Jae Hyung Kim),홍순조(Soon Jo Hong),최규보(Kyu Bo Choi) 대한내과학회 1996 대한내과학회지 Vol.50 No.6

N/A Objectives: Cardiogenic shock resulting from acute myocardial infarction is a serious complication with high mortality. The early identification of patients at high risk of developing post-infarction cardiogenic shock might allow early intervention in an attempt to prevent cardiogenic shock and to reduce the mortality due to cardiogenic shock. The aim of the present study was to examine the risk factors of inhospital development of cardiogenic shock among patients with acute myocardial infarction. Methods: We studied 152patients with acute myocardial infarction who were admitted to Kang-Nam St. Mary's hospital within 24hours after the onset of chest pain and did not have cardiogenic shack on admission between March 1991 and May 1994. Clinical data of these patients were analyzed. Results: Of 152patients, 17(11.1%) developed cardiogenic shock during their hospital stay. Cardiogenic shock developed in 53% of cases more than 24hours after admission. 82.4% of patients with cardiogenic shock died whereas a 6.7% in-hospital mortality was found among patients without cardiogenic shock. Multivariate regression analysis that controlled for variables affecting incidence of postinfarction cardiogenic shock showed that independent risk factors for in-hospital cardiogenic shock were history of myocardial infarction (adjusted relative odds[RO]=5.294, 95% confidence interval[CI]=2.149 to 13.041); heart failure on admission (RO=3.344, 95% CI=1.738 to 6.432); hyperglycemia (>180mg/dl) in non-diabetic patients (RO=3.270, 95% CI=1,590 to 6.727); age over 70 year old (RO=2.912, 95% CI= 1.816 to 4.668); ST deviation over 4mm (RO=2.417, 95% CI=1.225 to 4.767); peak LDH level greater than 1600U/ml (RO=1.154, 95% CI=1.080 to 1.233). Patients with one independent risk factor had an estimated probability of 10.5% for developing inhospital cardiogenic shock; patients with two independent risk factors, 48.5%, patients with three risk factors, 65.0% patients with four risk factors, 65.7% patients with five risk factors, 67.2%. Conclusion: Of post-infarction cardiogenic shock during admission, 53% developed more than 24hours after admission. The more independent risk factors on admission for inhospital cardiogenic shock patients with acute myocardial infarction had, the more likely in-hospital cardiogenic shock developed.

Extraordinarily selective adsorption of CO₂ over N₂ in a polyethyleneimine-impregnated NU-1000 material

Kang, Jo Hong,Yoon, Tae-Ung,Kim, Seo-Yul,Kim, Min-Bum,Kim, Hyung-Ju,Yang, Hee-Chul,Bae, Youn-Sang Elsevier 2019 Microporous and mesoporous materials Vol.281 No.-

<P><B>Abstract</B></P> <P>Developing an efficient adsorbent for selective separation and capture of CO<SUB>2</SUB> from CO<SUB>2</SUB>/N<SUB>2</SUB> mixture is an important and challenging issue for mitigating global warming. In this study, we posited that high CO<SUB>2</SUB>/N<SUB>2</SUB> selectivity could be obtained by impregnating polyethyleneimine (PEI) within the pores of NU-1000, a zirconium-based metal-organic framework (MOF), since it has a high surface area (∼2320 m<SUP>2</SUP>/g) and free and exposed OH groups but does not have unsaturated metal sites possibly having strong interactions with N<SUB>2</SUB> molecules. A series of PEI-impregnated NU-1000 (PEI(x)@NU-1000) materials with varied PEI loadings have been successfully prepared. As reasoned, PEI(50)@NU-1000 showed the highest CO<SUB>2</SUB>/N<SUB>2</SUB> selectivity among the PEI-loaded adsorbents in the literature under similar conditions. Remarkably, it exhibited extremely high CO<SUB>2</SUB>/N<SUB>2</SUB> selectivities (∼8000) at low pressures and a very high CO<SUB>2</SUB>/N<SUB>2</SUB> selectivity (661) at a typical pressure of flue gas (1 bar). Furthermore, PEI(50)@NU-1000 could efficiently separate CO<SUB>2</SUB>/N<SUB>2</SUB> mixture under a dynamic flow condition and maintained its CO<SUB>2</SUB> uptakes during three consecutive adsorption and desorption.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PEI was loaded in a MOF without open metal site to enhance CO<SUB>2</SUB>/N<SUB>2</SUB> selectivity. </LI> <LI> PEI species were loaded into a MOF through a wet impregnation method. </LI> <LI> PEI(50)@NU-1000 exhibits extremely high CO<SUB>2</SUB>/N<SUB>2</SUB> selectivity. </LI> <LI> PEI(50)@NU-1000 shows good CO<SUB>2</SUB>/N<SUB>2</SUB> separation under mixture flow condition. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

A Study on the Hydrodynamic Performance of Small Sized Fixed and Floating-moored OWC Wave Energy Converters by CFD and Experiment

HONG-GOO KANG(강홍구),CHAN JOO KIM(김찬주),HYODONG KANG(강효동),YEONG KYU KIM(김영규),HYO-JAE JO(조효제) 한국신재생에너지학회 2020 한국신재생에너지학회 학술대회논문집 Vol.2020 No.8

Fast and background-free three-dimensional (3D) live-cell imaging with lanthanide-doped upconverting nanoparticles

Jo, Hong Li,Song, Yo Han,Park, Jinho,Jo, Eun-Jung,Goh, Yeongchang,Shin, Kyujin,Kim, Min-Gon,Lee, Kang Taek The Royal Society of Chemistry 2015 Nanoscale Vol.7 No.46

The inhibitory function of Fc-ST2 depends on cell type; IL-1RAcP and ST2 are necessary but insufficient for IL-33 activity.

Hong, Kwangwon,Lee, Youngmin,Lee, Siyoung,Hong, Sungnoh,Bae, Suyoung,Hong, Jaewoo,Choi, Jida,Jhun, Hyunjhung,Kwak, Areum,Kim, Eunsom,Jo, Seunghyun,Kang, Taebong,Cho, You Sook,Kim, Yong-Gil,Kim, Soohyu S. Karger 2013 Immunologic research Vol.56 No.1

<P>IL-33 (IL-1F11) is a member of IL-1 family ligand, which stimulates the production of inflammatory cytokines. IL-33 receptor complex is comprised of IL-1 receptor accessory protein (IL-1RAcP) and ST2 that are activated by IL-33 ligand binding. ST2 is a ligand-binding chain of the IL-33 receptor component, and the soluble ST2 form possesses antagonistic activity. Here, we expressed the extracellular domain of ST2-fused to the immunoglobulin of IgG1 constant region in order to generate a soluble recombinant Fc-ST2. Human and mouse recombinant Fc-ST2 protein were expressed in Chinese hamster ovary cells and purified using a mini-protein A affinity chromatography. The recombinant Fc-ST2 protein was used to examine inhibitory function in IL-33-induced cytokine production in different cell types. The human Fc-ST2 abolished IL-33-induced IL-8 production in human mast cells, but mouse Fc-ST2 failed to inhibit IL-33-induced TNFα production in mouse Raw 264.7 macrophage cells. We further investigated the expression of IL-33 receptor component with various cell lines. IL-33 receptors expression pattern and Fc-ST2 inhibitory activity in different cell types suggest that IL-1RAcP and ST2 are necessary but insufficient for IL-33 activity. Our results suggest that an additional receptor component may participate in the biological activity of IL-33.</P>

산업미세먼지저감을 위한 막접촉기 탈황 스크러버 시스템 연구

강조홍(Jo Hong Kang),이강우(Gang-woo Lee),조성수(Sung-Su Cho),김병환,박진원(Jinwon Park),송호준(Hojun Song) 대한기계학회 2019 대한기계학회 춘추학술대회 Vol.2019 No.5

Molecular fingerprinting and tree-map of the Elytra Color Patterns of Harmonia axyridis, using AFLP analyses

Lee, Dae Hong,Eun Jin Kang,Hee Jin Lee,Hee Bong Seok,Chang Wook Jo,Cho Rong Park,Myoung Gi Kang,Mi Ja Seo,Young Nam Youn 한국응용곤충학회 2008 한국응용곤충학회 학술대회논문집 Vol.2008 No.05

The multicolored Asian ladybird beetle, Harmonia axyridis, which demonstrates typical genetic polymorphism in its elytra color patterns. Early studies have color polymorphism in terms of geographical clines while a few investigated temporal populations in Coccinellidae. Nevertheless, note that geographical and temporal morph variation does not always correspond to what is expected from thermal and industrial adaption theories. A recent study of transformation and RNAi of the ladybird beetle, however, there is yet no evidence to indicate the variation is genetic or environmental factors. Here we describe a relatively new molecular fingerprinting technique, amplified fragment length polymorphism (AFLP). Because we think that color polymorphism in Coccinellidae is affected by genetic polymorphism. In total 38 markers were scored from which some markers were polymorphic. Supsequent UPGMA cluster analysis revealed 3 major group of Harmonia axyridis populations. But for strains that are more genetically similar, different primer combinations may be need to generate enough polymorphic marker.