Distance Language Education Using Multimedia: A Case Study in Australia

Jung,Jae-Hoon(Jae Hoon Jung) 국제한국어교육학회 1997 한국어 교육 Vol.8 No.-

우관상정맥동에서 기시하는 단일 관상동맥 1예

정현광,김태우,조윤성,김강민,장재훈,이재우,정준훈 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Coronary artery anomalies are found incidentally in approximately 1% of all patients undergoing routine coronary angiography. Of these, an isolated single coronary artery anomaly is the rarest one. Patients with an isolated single coronary anomaly may present with symptoms such as angina pectoris, myocardial infarction, arrhythmias, syncope, sudden death, and congestive heart failure. We report a case of single coronary artery anomaly with the left anterior descending and left circumflex coronary artery originating from the right coronary artery.

2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

폐렴구균 감염증에서 항생제 내성의 임상적 의미 : Asian Network for Surveillance of Resistant Pathogens(ANSORP) Study

정숙인,기현균,손준성,고관수,김나영,장현하,오원섭,백경란,이남용,김신우,이혁,--,송재훈 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

목적 : 전 세계적으로 폐렴구균의 페니실린을 포함한 β-lactam과 마크로라이드 및 퀴놀론 계열의 항생제에 대한 내성이 급격히 증가하여 임상적으로 문제가 되고 있으나, 시험관내 내성이 실제 임상적 예후에 미치는 영향에 대해서는 아직까지 논란이 되고 있다. 본 연구는 폐렴구균의 항생제 내성률이 높은 아시아 지역에서 항생제 내성이 폐렴구균 감염증의 임상경과에 미치는 영향을 평가하기 위하여 시행되었다. 방법 : ANSORP에서 주관한 전향적 임상 연구로서 1999년 11월부터 2001년 8월까지 아시아 지역 11개국의 14개 기관에서 진단된 침습성 폐럼구균 감염증 환자를 대상으로 내성 균주 감염의 위험요인, 임상양상, 예후 등의 임상적 분석을 시행하였다. 결과 : 총 646명 환자의 평균연령은 30.1세(6일-89세)였고, 이전 3개월 내에 항생제 사용력이 있는 환자는 159명(32.4%)이었다. 질환별로는 폐렴이 377예(58.4%)로 가장 많았고, 중이염 67예, 뇌수막염 66예(10.2%), 일차성 균혈증 65예(10.1%)였다. 총 646균주 중 347균주(53.7%)가 페니실린 비감수성(중등도 내성 23.1%, 고도 내성 23.1%)이었고, 페니실린에 대한 MIC_(90)은 0.03㎍/mL에서 4㎍/mL까지의 분포를 보였다. 페니실린 비감수성 균주에 의한 감염증과 차이가 없었다. 페니실린 내성 폐렴구균 폐렴에 의한 사망률은 페니실린 감수성 폐렴구균 폐렴에 의한 사망률과 차이가 없었다(p=0.846). Erythromycin에 대한 고도 내성을 보이는 균주의 비율이 매우 높았으나, 실제 임상상이나 치사율에는 영향을 미치지 않았다(p=0.092). 페니실린 비감수성 폐렴구균에 의한 뇌수막염의 치사률도 감수성 균주에 의한 사망률과 차이가 없었다(p=0.059). 결론 : 본 연구의 결과 페니실린 및 베타 락탐 제제에 대한 시험관 내성은 폐렴구균 폐렴이나 뇌수막염의 임상상이나 치사율에 영향을 미치지 않는 것으로 확인되었다. 이는 내성의 정도와 연관될 것으로 생각되므로, 향후 고도 내성 균주가 증가할 때 추가 검증을 요한다. 아울러 macrolide 및 퀴놀론계 항생제 내성의 임상적 의미에 대한 후속 연구가 필요할 것으로 사료된다. Background : Despite the widespread emergence of antimicrobial resistance among pneumococcal strains worldwide, clinical implications of in vitro resistance still remain an open question. To evaluate the clinical impact of pneumococcal resistance in Asian countries where the prevalence of pneumococcal resistance was reported to be highest in the world, ANSORP has performed a prospective, multinational surveillance study with cases with invasive pneumococcal diseases in Asian countries. Methods : In vitro susceptibility of pneumococcal isolates was determined by broth microdilution tests with 16 antimicrobial agents. All enrolled cases of pneumococcal infections were analyzed with regard to demographic data, clinical features, risk factors and mortality. Results : A total of 646 patients with pneumococcal infections were enrolled from 14 centers in 12 countries between the period from November 1999 to August 2001. Pneumonia (58.4%) was the most common clinical disease followed by bacteremia (33.4%), otitis media (10.4%), and meningitis (10.2%). Among 646 isolates, 347 (53.7%) were penicillin non-susceptible (intermediate 23.1%, resistant 30.7%). MIG_(90)s for penicillin ranged from 0.03 (India) to 4.0 ㎍/mL (Korea, Taiwan, Vietnam, and Hong Kong). Overall mortality from pneumococcal diseases by penicillin non-susceptible strains was not different from that by susceptible strains. Pneumococcal pneumonia caused by penicillin- or erythromycin-resistant strains showed similar mortality, severity of illness, or complications to that by susceptible strains. Mortality from pneumococcal meningitis caused by penicillin non-susceptible strains was also similar to that by susceptible strains. Conclusion : Data suggest that current situation of in vitro resistance to penicillin or macrolides may not affect the mortality from pneumococal pneumonia or meningitis caused by antibiotic-resistant strains.

스코폴라민의 흰쥐 피부투과에 대한 투과촉진제들의 영향

정재영,감성훈,김건남,지상철,박은석 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

The transdermal therapeutic system (TTS) of scopolamine has various advantages over its oral dosage forms. The ideal scopolamine TTS requires high skin permeation rate in short time after it is applied on the skin. In order to increase the initial skin permeation rate of scopolamine from TTS, various permeation enhancers were employed. Enhancers employed were fatty acids(oleic and linolenic acids), cyclic monoterpenes(menthol, camphor, cineole and limonene) and others(isopropyl myristate, sodium lauryl sulfate and glyceryl monostearate). The concentration of enhancers in the base were fixed to 5% (w/w). While fatty acids had little enhancing effect on the skin permeation of scopolamine, cyclic monoterpenes, isopropyl myristate and sodium lauryl sulfate resulted in 1.5∼2.36-fold higher skin permeation rate of the drug compared to the control. However, lag time was not affected by enhancers studied.

禮山地方의 사과産業 發展 方案에 關한 硏究

鄭載薰 公州大學校 資源科學硏究所 1996 資源科學硏究論文集 Vol.4 No.-

This study was investigated a real management condition and the development of apple industry in Yesan region. The generate a few possible alternative for raising and the present condition of cultivation from free inportation of Agiricultural product in Yesan region. The results obtained un this study were summarized as follows; 1.The present condition of cultivation was 1,995 apple culture farms and the farms of average cultivated land was 2,184 Pyeong. 2.The farm of cultivated land was that 1ha under 361 farms, 1-2ha size cultivated land was 1,214 farms, 2ha over size was 390 farms. 3.The apple product quantity was 37,000M/T, the amount of production was 35,000million won and the amount of consumption per a man was 16.1kg. 4.The apple expert quantity was 28M/T and the amount of export was 40 million won. 5.The size for height of trees were in the order of steady, thinning-out only (T pruning) <steady, short, heading-back only (H pruning) < steady, long heading-back with thinning-out only (H+T pruning)=three years short heading-back only then thinning-out only (3HT pruning). 6.The proper cultivated land and magnifying of labor-saving culture were.

기관지석으로 발현한 기관지성 방선균증 1예

정숙인,천정학,홍종락,고영민,정만표,권오정,이종헌,백경란,송재훈 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

기관지성 방선균증은 매우 예외적이고 드물며 임상양상이 다양하여 폐암과의 감별이 어렵기도 하지만 기관지내시경 검사를 통해 진단할 수 있고 항생제 투여로 완치될 수 있는 질환이다. 저자들은 기관지석과 함께 발현한 기관지성 방선균증을 장기간의 경구 항생제 요법으로 완치한 1례를 경험하였기에 보고하는 바이다. Endobronchial actmomycosis is considered as an exceptional event. We report a case of a 49-year-old woman who presented with cough and exertional dyspnea for 20 months. Her chest X-ray showed calcified lymph nodes in the right lower paratracheal and subcarinal area and consolidation in the right middle lobe. Bronchoscopic examination demonstrated whitish broncholithiasis with mucosal nodularity in the bronchus intermedius obstructing the lumen near-completely. The biopsy specimen revealed sulfur granules and calcified material which were consistent with actmomycosis. Prolonged oral antibiotic treatment resulted in complete recovery, without need for surgical resection.

일개 대학병원에서 경험한 방선균증의 임상상

정숙인,김연숙,기현균,김춘관,김신우,이혁,김성민,백경란,송재훈 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.3

배경 : 방선균증은 혐기성의 그람양성 간균에 의한 만성 화농성 감염으로, 경안면부, 흉부, 복부, 골반부 등을 주로 침범한다. 최근 구강 위생의 향상과 항생제의 사용으로 인해 방선균증의 빈도의 감소와 함께 그 임상양상 또한 크게 변화하였다. 저자들은 국내에서의 방선균증의 임상상을 분석하기 위해 본 연구를 시행하였다. 방법 : 1995년 5월부터 1998년 9월까지 삼성서울병원에서 방선균증으로 진단받은 환자를 대상으로 임상기록지를 토대로 감염병소와 임상경과 등을 후향적으로 조사하였다. 결과 : 방선균증 환자는 모두 12명으로 경안면부 1례, 흉부 3례, 복부 3례, 골반부 5례였다. 임상양상은 주로 종괴의 형태로 나타나 진단을 내리기까지 종양과의 감별에 어려웠으며 진단은 모두 조직검사나 흡인액에서 유황과립을 확인함으로써 이루어졌다. 방선균증으로 진단된 환자는 모두 호전소견을 보였다. 결론 : 국내에서도 방선균증이 드물지 않게 발생하고 있으며 임상양상이 다양하여 가장 많이 오진되는 질환 중의 하나이다. 방선균증은 조직검사나 균배양검사를 통해 진단하고 항생제를 통해 완치될 수 있는 질환이므로 환자 진단에 관심을 가지면 불필요한 수술을 피할 수 있을 것으로 생각된다. Background: Actinomycosis is an indolent, slowly progressive bacterial infection, caused by Actinomyces. a gram-positive, non-spore-forming anaerobic or microaerophilic rod. Actinomycosis affects nearly every organ and body site. The disease is classically divided into four types, depending on the anatomic sites involved: cervicofacial, thoracic, abdominal, and pelvic. It has been considered as a rare disease, and only several cases have been reported in Korea. We performed this study to analyse the clinical manifestations of actinomycosis in Korea. Method: We retrospectively reviewed the medical records of patients with actinomycosis at the Samsung Medical Center from May 1995 to December 1998. Results: During the study period, actinomycosis was diagnosed in 12 patients: 1 patient had cervicofacial lesion, 3 thoracic, 3 abdominal, and 5 pelvic. The male and female ratio was 1 : 2 and the mean age was 47.2 years. Sulfur granule was observed in the pathologic specimens from all cases, but organism did not grow at all. It was very difficult to differentiate actinomycosis from tumorous conditions without pathologic diagnosis. All patients were clinically improved with antibiotics or surgical procedures. Conclusion: Actinomycosis is not a rare disease nowadays and has various clinical manifestations. It can be diagnosed by pathologic examination or culture and cured by antibiotics without surgical management.

矮性사과나무 樹體生長 果實의 收量과 品質에 對한 몇가지 다른 剪定方法間의 比較 硏究

鄭載薰 公州大學校 資源科學硏究所 1993 資源科學硏究論文集 Vol.1 No.-

A series of experiment was carried out to contribute in establishing a model of pruning through investigating in relation to the tree form, tree vigour, yield and fruit quality in 4-examplary orchards practising unique pruning methods. The major results can be summarized as follows. 1. Sizes for height of trees were in the order of steady, thinning-out only("T" pruning)<steady, short, heading-back only("H" pruning)< steady, long heading-back with thinning-out only("H+T" pruning)=three years short heading-back only then thinning-out only("3HT" pruning). 2. The number of flower buds per 10a of branch was in the of three years short, heading-back only then thinning-out only> steady, thinning-out only> steady, short, heading-back only> steady, long heading-back with thinning-out only. Also, the size of flower bud for 6-year old 'Fuji' apple tree was in the order of steady, thinning-out only> three years short, heading-back only then thinning-out then thinning-out only> steady, short, heading-back only = steady, long heading-back with thinning-out only. 3. The carbohydrate/nitrogen(C/N) ratio in bark of one-year-old shoot was high in steady, thinning-out only and was low on the other three pruning treatments. 4. In accumulated yield for 8 years of cropping, the fruit number per 10a was in the order of steady, thinning-out only=steady, short, heading-back only>three years' short, heading-back only then thinning-out only. Also the yield per 10a was in the order of steady, thinning-out only > steady, short, heading-back > steady, long heading-back with thinning-out only = three years' short, heading-back 5. The percentage of incident light intensity, relative to the outer canopy, into the innermost part of the canopy belonging 1.0m-1.5m abvoe the ground and within the radius of 0.5m around the main stem, was in the order of steady, thinning-out only > three years' short, heading-back only then thinning-out only > steady, short, heading-back only = steady, long heading-back with thinning-out only. 6. The distribution percentages of fruits coloured with 60% and over were in the order of steady, thinning-out only > three years' short, heading-back only then thinning-out then only = steady, long heading-back with thinning-out only > steady, short, heading-back only. While the distribution percentages of fruits weighting over 300g each were in the order of steady, long heading-back with thinning-out only = steady, thinning-out only;> three years' short, heading-back only then thinning-out only = steady, long heading-back with thinning-out only. 7. The content of chlorophyll b in fruit skin from steady, thinning-out only pruning treatment was less while the content of anthocyanin in fruit skin from steady, thinning-out only pruning treatment was compared with the other three pruning teatment, respectively. 8. The soluble solid contents of fruits were in the order of steady, thinning-out only > three years' short, heading-back only then thinning-out only> steady, long heading-back with thinning-out only. While the titratable acidity content was higher in steady, thinning-out pruning then the other three pruning treatments.

상악전치부 심미에 대한 인식도 평가

정재훈,오상천 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

This study was undertaken to determine the Korean perception of the altered anterior dental esthetics including the lack of symmetry, the midline deviation, the gingival exposure, the inclination of incisal plane, the type of incisal plane, and the type of gingival line. 670 subjects were participated in this survey. A questionnaire accompanied by 12 sets of computer-manipulated images using 3D MAX 4.2 software was used to record the ranking of the geometric preference related to the anterior esthetic discrepancies in three or four degrees of alteration. The statistical significance of the differences between the groups was determined by a one-way ANOVA and a t-test. The results obtained were as follows: 1. The Korean perception of the anterior dental esthetics according to the subjects' occupation, sex, and age was most affected by occupation. 2. The masked image emphasizing the dentition and lips appeared stranger than the non-masked image at the same alteration. 3. The lack of symmetry, which was expressed as a unilateral discoloration of the tooth, showed incongruity in any teeth of the anterior dentition. The incongruity was more severe as the degree occurred closer to the midline, 4. The deviation of midline was showed more severe strangeness as the degree of deviation increased. However, more than half of the subjects did not perceive a deviation of 5mm. 5. During smiling, the exposure of the upper gingiva showed more severe incongruity as the degree of gingival exposure increased. 77% of the subjects perceived strangeness at the gingival exposure of 4.5mm. 6. The inclination of the incisal plane appeared stranger as the degree of inclination increased. 62% of subjects perceived strangeness at the 7.5˚ inclination of the incisal plane. 7. The type of incisal plane showed increasing strangeness in the order of convex/downward, straight/horizontal, and concave/upward. 80% of subjects perceied strangeness at concave/upward. 8. The type of gingival line was showed increasing incongruity in the order of the same, a little above, and a little under the zenith of the lateral incisor to the line joining the zenith of the central incisor and the canine. However, less than half the subjects did not perceive strangeness at any alteration of the gingival line.