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A Case Report of Gynecomastia Due to Rosuvastatin
정준훈,김윤성,이상권 대한가정의학회 2019 Korean Journal of Family Practice Vol.9 No.5
Gynecomastia is a common benign disease characterized by the progressive enlargement of the glandular tissue of the male breast due to an imbalance between the levels of estrogen and androgen in the blood. The etiology may vary and may be physiological, pharmacological, pathological, or even idiopathic. Among men, drug-induced gynecomastia may account for 10% to 20% of cases. The literature contains six case reports of rosuvastatin-induced gynecomastia. Withdrawal of statin or switching to a less potent statin can lead to symptom improvement and avoidance of unnecessary tests and patient anxiety. A 62-year-old male patient developed unilateral gynecomastia after 13 months of rosuvastatin therapy. After switching to a different statin (pravastatin), his symptoms improved within 2 months. Thus, clinicians should be aware of the possibility of occurrence of gynecomastia when statins are prescribed.
정준훈,박용현,김윤성 대한가정의학회 2023 Korean Journal of Family Practice Vol.13 No.3
Heat stroke is a life-threatening illness characterized by an elevated core temperature of >40℃ and dysfunction of the central nervous system, resulting in delirium, convulsions, or coma. Stress cardiomyopathy is characterized by transient regional systolic dysfunction of the left ventricle mimicking myocardial infarction in the absence of angiographic evidence of obstructive coronary artery disease or acute plaque rupture. A 63-year-old man with a history of hypertension visited the emergency room because of convulsions and fever. On arrival, he was in a stupor with a rectal temperature of 40.6℃. A rapid infusion of 1.5 liters of cold isotonic sodium chloride solution was initiated, as was surface cooling with an ice pack. An electrocardiogram revealed ST-segment depression in leads V4–6. Echocardiography revealed a reduced left ventricular ejection fraction (LVEF) of 30% and basal wall hypokinesia. Coronary angiography revealed no obstruction in both coronary arteries. Fourteen days later, follow-up echocardiography showed complete recovery of the LV wall motion with an EF of 64%. We report a rare case of inverted stress cardiomyopathy due to heat stroke.